Understanding and interpreting a PRRS diagnosis in the context of “disease stages”

The article discusses issues related to the effectiveness of diagnostics of persistent infections. Using PRRS as an example, the relationship between “disease stages” and “diagnostic stages” is discussed on the basis of a meta-analysis of data from diagnostic studies (n = 4307 results) presented in refereed scientific papers to understand the key points. Despite the ongoing improvement of diagnostic methods, none of them individually can be recognized as the only correct decision: the choice of the type of sample and test for research depends on the specific task. In most cases, to establish the true picture of an epizootic, it is necessary to use several research methods and / or types of samples.

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Research methods and evidence-based medicine

Oxford Textbook of Global Health of Women, Newborns, Children, and Adolescents ◽

10.1093/med/9780198794684.003.0004 ◽

2018 ◽

pp. 19-24

Author(s):

Tim Colbourn

Keyword(s):

Research Methods ◽

Meta Analysis ◽

Research Question ◽

Secondary Data ◽

Evidence Base ◽

Primary Data ◽

Key Points ◽

Study Type ◽

Based Medicine ◽

And Child Health

This chapter provides an overview of research methods used to build the evidence base for global maternal and child health. It covers primary data collection, secondary data analysis, systematic reviews, and meta-analysis, and provides tips on how to interpret the scientific literature. This chapter should be read in conjunction with Chapters 1–3, Chapter 5 on economic evaluation, and Chapter 4 on converting research into policy to put the use of research evidence into context. The three key points from this chapter are: (1) you need to clearly define a research question before deciding what study type is best suited to answer it; (2) designing a research study involves detailed attention to practical details, including how groups are going to be defined; and (3) scientific studies are sometimes published with incorrect conclusions. Critically appraise each study, and define appropriate conclusions that are based on the data and methodology.

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Meta-analysis of corporate governance in Asia

Investment Management and Financial Innovations ◽

10.21511/imfi.15(2).2018.24 ◽

2018 ◽

Vol 15 (2) ◽

pp. 267-280 ◽

Cited By ~ 2

Author(s):

Niki Lukviarman ◽

Arief Prima Johan

Keyword(s):

Corporate Governance ◽

Negative Impact ◽

Meta Analysis ◽

Research Process ◽

Inconsistent Result ◽

Rigorous Research ◽

Scientific Papers ◽

Outside Director ◽

Relationship Of ◽

The Relationship

Research on corporate governance has been conducted extensively over the past few decades. However, the result of various studies failed to produce conclusive insight. This study is aimed at identifying, classifying, analyzing and interpreting previous research on corporate governance in Asia by using meta-analytical approach. By using the HOMA (Hedges-Olkin Meta-Analytical) procedures, the current study collected eighty articles from journals ranging from 1999 until 2017. Data were gathered from empirical scientific papers. Through rigorous research process, the current study found that most previous research on corporate governance in Asia observed the patterns of influence of various types of ownership structure and board characteristics on corporate performance. Ownership by family, government, and management tend to have a negative impact on performance, whilst institutional ownership and foreign ownership show positive effect on performance. The study reveals inconsistent result for frequency of board meetings, existence of family members on board, outside director, and board independence towards performance. Similar finding appeared for the relationship of performance to women on board and CEO duality. CGPI as the Corporate Governance Perception index and board size were found to have a positive consistency on performance. Apart from limitations of the study, the result suggests that there exists institutional and environmental specificity in the study of corporate governance in Asia that may be different from other context of study so that future researcher need to take a precaution of this matter.

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Relationship between total plasma homocysteine and the risk of aneurysms – a meta-analysis

VASA ◽

10.1024/0301-1526/a000891 ◽

2020 ◽

pp. 1-6

Author(s):

Hanji Zhang ◽

Dexin Yin ◽

Yue Zhao ◽

Yezhou Li ◽

Dejiang Yao ◽

...

Keyword(s):

Large Scale ◽

Meta Analysis ◽

Single Species ◽

Total Plasma ◽

Control Groups ◽

Randomized Controlled ◽

Randomized Controlled Studies ◽

The Difference ◽

The Relationship ◽

Healthy Participants

Summary: Our meta-analysis focused on the relationship between homocysteine (Hcy) level and the incidence of aneurysms and looked at the relationship between smoking, hypertension and aneurysms. A systematic literature search of Pubmed, Web of Science, and Embase databases (up to March 31, 2020) resulted in the identification of 19 studies, including 2,629 aneurysm patients and 6,497 healthy participants. Combined analysis of the included studies showed that number of smoking, hypertension and hyperhomocysteinemia (HHcy) in aneurysm patients was higher than that in the control groups, and the total plasma Hcy level in aneurysm patients was also higher. These findings suggest that smoking, hypertension and HHcy may be risk factors for the development and progression of aneurysms. Although the heterogeneity of meta-analysis was significant, it was found that the heterogeneity might come from the difference between race and disease species through subgroup analysis. Large-scale randomized controlled studies of single species and single disease species are needed in the future to supplement the accuracy of the results.

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Staring Down Death

Crisis ◽

10.1027/0227-5910/a000367 ◽

2016 ◽

Vol 37 (3) ◽

pp. 212-217 ◽

Cited By ~ 7

Author(s):

Thomas E. Joiner ◽

Melanie A. Hom ◽

Megan L. Rogers ◽

Carol Chu ◽

Ian H. Stanley ◽

...

Keyword(s):

Suicide Risk ◽

Clinical Utility ◽

Blink Rate ◽

Specific Task ◽

Careful Planning ◽

Eye Blink ◽

Eye Blinks ◽

Potential Clinical Utility ◽

The Relationship

Abstract. Background: Lowered eye blink rate may be a clinically useful indicator of acute, imminent, and severe suicide risk. Diminished eye blink rates are often seen among individuals engaged in heightened concentration on a specific task that requires careful planning and attention. Indeed, overcoming one’s biological instinct for survival through suicide necessitates premeditation and concentration; thus, a diminished eye blink rate may signal imminent suicidality. Aims: This article aims to spur research and clinical inquiry into the role of eye blinks as an indicator of acute suicide risk. Method: Literature relevant to the potential connection between eye blink rate and suicidality was reviewed and synthesized. Results: Anecdotal, cognitive, neurological, and conceptual support for the relationship between decreased blink rate and suicide risk is outlined. Conclusion: Given that eye blinks are a highly observable behavior, the potential clinical utility of using eye blink rate as a marker of suicide risk is immense. Research is warranted to explore the association between eye blink rate and acute suicide risk.

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A Meta-Analysis of Interviews and Cognitive Ability

Journal of Personnel Psychology ◽

10.1027/1866-5888/a000091 ◽

2013 ◽

Vol 12 (4) ◽

pp. 157-169 ◽

Cited By ~ 7

Author(s):

Philip L. Roth ◽

Allen I. Huffcutt

Keyword(s):

Cognitive Ability ◽

Meta Analysis ◽

Incremental Validity ◽

Employment Interviews ◽

Moderator Analysis ◽

The Future ◽

Research Questions ◽

Meta Analyses ◽

The Relationship

The topic of what interviews measure has received a great deal of attention over the years. One line of research has investigated the relationship between interviews and the construct of cognitive ability. A previous meta-analysis reported an overall corrected correlation of .40 ( Huffcutt, Roth, & McDaniel, 1996 ). A more recent meta-analysis reported a noticeably lower corrected correlation of .27 ( Berry, Sackett, & Landers, 2007 ). After reviewing both meta-analyses, it appears that the two studies posed different research questions. Further, there were a number of coding judgments in Berry et al. that merit review, and there was no moderator analysis for educational versus employment interviews. As a result, we reanalyzed the work by Berry et al. and found a corrected correlation of .42 for employment interviews (.15 higher than Berry et al., a 56% increase). Further, educational interviews were associated with a corrected correlation of .21, supporting their influence as a moderator. We suggest a better estimate of the correlation between employment interviews and cognitive ability is .42, and this takes us “back to the future” in that the better overall estimate of the employment interviews – cognitive ability relationship is roughly .40. This difference has implications for what is being measured by interviews and their incremental validity.

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The Relationship Between Immorality and Cleansing

Social Psychology ◽

10.1027/1864-9335/a000349 ◽

2018 ◽

Vol 49 (5) ◽

pp. 303-309 ◽

Cited By ~ 3

Author(s):

Jedidiah Siev ◽

Shelby E. Zuckerman ◽

Joseph J. Siev

Keyword(s):

Effect Size ◽

Meta Analysis ◽

Weighted Mean ◽

The Relationship

Abstract. In a widely publicized set of studies, participants who were primed to consider unethical events preferred cleansing products more than did those primed with ethical events ( Zhong & Liljenquist, 2006 ). This tendency to respond to moral threat with physical cleansing is known as the Macbeth Effect. Several subsequent efforts, however, did not replicate this relationship. The present manuscript reports the results of a meta-analysis of 15 studies testing this relationship. The weighted mean effect size was small across all studies (g = 0.17, 95% CI [0.04, 0.31]), and nonsignificant across studies conducted in independent laboratories (g = 0.07, 95% CI [−0.04, 0.19]). We conclude that there is little evidence for an overall Macbeth Effect; however, there may be a Macbeth Effect under certain conditions.

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