scholarly journals Unmasking of miliary tuberculosis in COVID-19: A case report

2021 ◽  
pp. 458-460
Author(s):  
Astha Guliani ◽  
Lokesh Kumar Lalwani ◽  
Krishan Bihari Gupta ◽  
Prem Parkash Gupta ◽  
Vishal Raj
Keyword(s):  
Tertiary Care ◽  
Miliary Tuberculosis ◽  
North India ◽  
Mantoux Test ◽  
Chest Roentgenogram ◽  
Family Welfare ◽  
Care Hospital ◽  
Early Recovery ◽  
Loss Of Weight ◽  
Anti Tubercular Therapy

Both coronavirus disease-19 (COVID-19) and pulmonary tuberculosis (PTB) are transmitted through the respiratory route and are related to various risk factors. The index case was a 45-year-old female who presented to a tertiary care hospital in North India with complaints of dry cough, loss of weight, and appetite for twenty days followed by fever and dyspnea for five days. RT-PCR for COVID-19 turned out positive. Chest-roentgenogram revealed bilateral homogenous micronodules. She was started on COVID-19 treatment according to the Ministry of Health and Family Welfare guidelines. She was not clinically improved so CECT-thorax was performed which revealed bilateral homogenous millet-shaped micronodular opacities. Mantoux test was twenty-five millimeters in size but sputum analysis for acid-fast bacilli was negative. The patient was started on anti-tubercular-therapy (ATT). The patient got improved clinically and is being followed. This case focuses on the need for prompt diagnosis of PTB in COVID patients for the appropriate management and early recovery.

Diagnostic Role of Serum Adenosine Deaminase in Miliary Tuberculosis: Experience From a Tertiary Care Hospital in North India

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 264A
Author(s):  
Prasanta Mohapatra ◽  
Deepak Aggarwal ◽  
Rahul Katyal ◽  
C. Prashanth ◽  
Deepak Tekke ◽  
...  
Keyword(s):  
Adenosine Deaminase ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Miliary Tuberculosis ◽  
North India ◽  
Care Hospital ◽  
Diagnostic Role

The Spectrum of Skin Biopsies from a Tertiary Care Hospital in North India

2016 ◽  
Vol 2 (5) ◽  
Author(s):  
Abhilasha Williams ◽  
Anuradha Bhatia ◽  
EmyAbi Thomas ◽  
Clarence J Samuel
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Skin Biopsies

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

Epidemiology and clinical outcome of ventilator-associated events at a tertiary care hospital from North India

2020 ◽  
pp. 004947552098245
Author(s):  
Pooja Kumari ◽  
Priya Datta ◽  
Satinder Gombar ◽  
Deepak Sharma ◽  
Jagdish Chander
Keyword(s):  
Mechanical Ventilation ◽  
Tertiary Care Hospital ◽  
Late Onset ◽  
Tertiary Care ◽  
Control Measures ◽  
North India ◽  
Ventilator Associated Pneumonia ◽  
Care Hospital ◽  
Infection Control Measures ◽  
Utilisation Rate

The aim of our study was to determine the incidence, microbiological profile, risk factors and outcomes of patients diagnosed with ventilator-associated events in our tertiary care hospital. In this prospective study, intensive care patients put on mechanical ventilation for >48 h were enrolled and monitored daily for ventilator-associated event according to Disease Centre Control guidelines. A ventilator-associated event developed in 33/250 (13.2%); its incidence was 3.5/100 mechanical ventilation days. The device utilisation rate was 0.86, 36.4% of patients had early and 63.6% late-onset ventilator-associated pneumonia whose most common causative pathogen was Acinetobacter sp. (63.6%). Various factors were significantly associated with a ventilator-associated event: male gender, COPD, smoking, >2 underlying diseases, chronic kidney disease and elevated acute physiological and chronic health evaluation II scores. Therefore, stringent implementation of infection control measures is necessary to control ventilator-associated pneumonia in critical care units.

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