scholarly journals Tuberculous osteomyelitis of proximal fibula: An unusual presentation of tuberculosis

2021 ◽  
pp. 402-404
Author(s):  
Gunjar Jain ◽  
Asjad Mahmood ◽  
Hira Lal Nag ◽  
Pranav Gupta ◽  
Vikram Raj Gopinathan ◽  
...  
Keyword(s):  
Needle Aspiration ◽  
Resonance Imaging ◽  
Chain Reaction ◽  
Aspiration Cytology ◽  
Proximal Fibula ◽  
Tuberculous Osteomyelitis ◽  
Rare Site ◽  
Polymerase Chain ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

Tubercular involvement of the proximal fibula is rare. We present a case of tuberculosis of proximal fibula in an immunocompetent 22-year-old female. She was diagnosed clinically as a case of cellulitis. Radiological investigations, including magnetic resonance imaging revealed a destructive lesion in her right proximal fibula. Finally, by fine-needle aspiration cytology and GeneXpert polymerase chain reaction, a diagnosis of tuberculous osteomyelitis of proximal fibula was established. She was managed non-operatively with multidrug antitubercular chemotherapy. A high index of suspicion is required to make a diagnosis of musculoskeletal tuberculosis of such a rare site in the early stages.

scholarly journals Tubercular mastitis: An institutional experience from a tertiary care centre of northern India

2017 ◽  
Vol 8 (3) ◽  
pp. 72-75
Author(s):  
Amit Gupta ◽  
Lovenish Bains ◽  
Deepshikha Yadav ◽  
Prashant Durgapal ◽  
Manish Kumar Agrawal
Keyword(s):  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Centre ◽  
Medical Sciences ◽  
Tertiary Care Centre ◽  
Aspiration Cytology ◽  
Northern India ◽  
Institutional Experience ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

Background: Tuberculous mastitis (TM) is a rare extra pulmonary presentation of tuberculosis. It may be problematic to distinguish from carcinoma breast, a condition with which it may coexist.  Fine needle aspiration cytology (FNAC) / biopsy are indispensable for diagnosis and tuberculosis culture when positive may be very valuable to guide antimicrobial therapy.Aims and Objectives:  To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and Methods: 19 cases of tubercular mastitis between  January 2012 to March 2014 were identified and included in the present study. Cytology and biopsy alongwith AFB stain was done for confirmation.Results: Age ranged between 23- 55 years (median 33 years). Axillary nodes were palpable in 9 (47.3%) patients. Acid Fast Bacilli stain which was positive in only 3 patients. All the 19 patients were started on antitubercular treatment.Conclusion: This study highlights the importance of early diagnosis and aggressive medical and if required surgical management to cure this disease.Asian Journal of Medical Sciences Vol.8(3) 2017 72-75

scholarly journals A Case of Primary Tubercular Mastitis Masquerading as Carcinoma Breast

2011 ◽  
Vol 2011 ◽  
pp. 1-2
Author(s):  
Sameer Singhal
Keyword(s):  
Extrapulmonary Tuberculosis ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
True Nature ◽  
Potential Case ◽  
Surgical Options ◽  
Needle Aspiration Cytology ◽  
Important Position ◽  
High Index Of Suspicion

Primary extrapulmonary tuberculosis occurring in the breast is extremely rare. In the absence of well-defined clinical features, the true nature of the disease remains obscure and it is often mistaken for carcinoma or pyogenic breast abscess. It also presents a diagnostic problem on radiological and microbiological investigations and thus high index of suspicion acquires an important position. This paper highlights the importance of considering every breast lump as a potential case of tubercular mastitis especially in endemic countries like India that should be subjected to fine needle aspiration cytology or excisional biopsy before considering surgical options like complete mastectomy, without relying only on clinicoradiological findings.

scholarly journals Problems and Solution to Diagnose Extrapulmonary Tuberculosis in Central Region of Nepal

Med Phoenix ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 41-43
Author(s):  
Ravi Shankar Gupta ◽  
Tarannum Khatun ◽  
Akhtar Alam Ansari ◽  
Amrullah Shidiki ◽  
Dipak Bhargava ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Mycobacterium Tuberculosis ◽  
Correct Diagnosis ◽  
Extrapulmonary Tuberculosis ◽  
Needle Aspiration ◽  
Retropharyngeal Abscess ◽  
Chain Reaction ◽  
Specificity And Sensitivity ◽  
Polymerase Chain ◽  
Needle Aspiration Cytology

Extrapulmonary Tuberculosis is high, challenging the clinicians to make correct diagnosis. Microscopy, culture and fine needle aspiration cytology have their limitations in regard to specificity and sensitivity. In this report, polymerase chain reaction is used for detecting and distinguishing Extrapulmonary Tuberculosis. A case of retropharyngeal abscess was selected from which pus was collected which was negative for microscopy and culture in routine microbiology as well as mycobacteriology. Cytopathological examination was also negative. Polymerase chain reaction was applied to detect Mycobacterium tuberculosis specific IS6110 gene. The patients responded with anti-tuberculosis treatment well. Polymerase chain reaction was introduced for diagnosis of Extrapulmonary Tuberculosis since it can be done within hours, monitor therapy and also differentiate Mycobacterium tuberculosis from other Mycobacterial species.MED Phoenix Volume (1), Issue (1) July 2016, page: 41-43

scholarly journals Tuberculous Mastitis: Experience of Five Cases at a Tertiary Care Hospital

2016 ◽  
Vol 4 (2) ◽  
pp. 67-70
Author(s):  
Md Hasanuzzaman ◽  
Md Johirul Islam ◽  
AZM Mostaque Hossain ◽  
Mohammad Zillur Rahman ◽  
Md Ashraf Ul Haque ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Surgical Oncology ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Aspiration Cytology ◽  
Antitubercular Drugs ◽  
Granulomatous Lesions ◽  
Needle Aspiration Cytology ◽  
Breast Lumps ◽  
High Index Of Suspicion

Background: Tuberculous Mastitis (TM) is a rare form of tuberculosis, even in countries where the burden of tuberculosis is high. It may mimic other systemic illness, even carcinoma breast, a condition with which it may coexist.Objective: To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and method: This observational study was carried out in the department of Surgical Oncology of National Institute of Cancer Research & Hospital (NICRH), Dhaka, Bangladesh from January 2010 to December 2015. During the study period only five cases of TM were identified and all were included in the analysis purposively.Results: Mean(±SD) age of the patients was 27.2(±16.22) years. AFB in pus was found in one patient. Fine Needle Aspiration Cytology (FNAC) was done in four AFB negative patients and granulomatous lesions were found in each case. Histopathological examinations of two resected breast lumps also showed granulomatous lesions consistent with tuberculosis. Breast ultrasound showed multilocular abscess with ill-defined lump in two cases, solitary lump in two patients and cystic lesion in one patient. Axillary lymphadenopathy was found in one patient with solitary lump. Repeated image guided aspiration of the abscess was performed in 3 cases. Two patients underwent lumpectomy operation. All five patients were given anti-TB chemotherapy for 6 months. All of them recovered fully after completion of Category I treatment.Conclusion: Though it is a great mimicker with proper evaluation the disease is curable with antitubercular drugs, and in some cases surgery is required.Delta Med Col J. Jul 2016 4(2): 67-70

Incidence of malignancy in solitary thyroid nodules

2015 ◽  
Vol 129 (7) ◽  
pp. 677-681 ◽  
Author(s):  
S M Keh ◽  
S K El-Shunnar ◽  
T Palmer ◽  
S F Ahsan
Keyword(s):  
Thyroid Surgery ◽  
High Probability ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignancy Rate ◽  
The Mean ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

AbstractObjectives:This study aimed to investigate the prevalence and clinical significance of solitary thyroid nodules in patients who underwent thyroid surgery.Methods:A retrospective review was performed of the case notes of all adult patients who underwent thyroid surgery from January 2003 to December 2009. All patients with solitary thyroid nodules identified by ultrasonography were included.Results:In total, 225 patients underwent thyroid surgery. The prevalence of solitary thyroid nodules was 27.1 per cent (61 out of 225 patients). Seventy-two per cent of patients were women and the mean age at presentation was 52 ± 16 years. In all, 75.4 per cent of solitary nodules had neoplastic pathology and the malignancy rate was 34.4 per cent. The sensitivity and specificity of fine needle aspiration cytology for neoplasm detection were 73.9 per cent and 80.0 per cent, respectively. There was no association between the various ultrasonography parameters and malignancy risk (p > 0.05).Conclusion:Solitary thyroid nodules should be investigated thoroughly with a high index of suspicion because there is a high probability (34.0 per cent) of malignancy.

The changing faces of a parotid mass

1999 ◽  
Vol 113 (10) ◽  
pp. 938-941 ◽  
Author(s):  
S. S. Hehar ◽  
J. Dugar ◽  
J. Sharp
Keyword(s):  
Ultrasound Guidance ◽  
Correct Diagnosis ◽  
Needle Aspiration ◽  
Resonance Imaging ◽  
Aspiration Cytology ◽  
Complete Excision ◽  
Fine Needle ◽  
Definitive Surgery ◽  
Needle Aspiration Cytology ◽  
Incision Biopsy

AbstractThe development of a neurofibroma in the temporal and parotid regions of the facial nerve is rare. We report a case occurring in a 32-year-old male, where the initial presentation was a parotid mass. Cytologically this was initially thought to be a pleomorphic adenoma. However, the diagnosis was then changed to a schwannoma and finally a neurofibroma after complete excision of the lesion. The case illustrates how fine needle aspiration cytology under ultrasound guidance, and even histological examination of an incision biopsy can sometimes fail to give the correct diagnosis. In this case magnetic resonance imaging was used to help plan definitive surgery.

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