Investigation of the possible effectiveness of osteopathic correction in the complex treatment of children in the first year of life with hip dysplasia

2021 ◽  
pp. 39-49
Author(s):  
N. A. Fabristova ◽  
I. R. Gainullin

Introduction. Congenital dysplasia of the hip joints is one of the main among congenital diseases of the musculoskeletal system in children and requires a long period of treatment, including in a hospital settings. Standard methods of treatment contain the orthopedic and rehabilitation measures: the use of abduction splints, a complex of physiotherapy exercises, general massage, the use of various physiotherapeutic procedures. Osteopathic correction is not included in the standards of care for this category of patients. At the same time, these standard treatment methods do not always give a desired result, and sometimes even lead to the development of complications. All this facts determines the need to search for additional therapeutic techniques.The aim of the study is to research the possible effectiveness of osteopathic correction as part of the complex treatment of children in the first year of life with hip dysplasia.Materials and methods. The study included 34 children with a diagnosis of hip dysplasia (ICD code-10 — Q65.8). The patients were randomly divided into 2 equivalent groups: study and control. Participants in both groups received standard treatment; the participants of the main group additionally underwent osteopathic correction of the revealed somatic dysfunctions. Before and after the course of treatment, the patients' osteopathic status, the disease clinical manifestations, and the X-ray data of the hip joints were assessed.Results. The inclusion of osteopathic correction in the complex with standard treatment procedures for children of the first year of life with hip dysplasia is accompanied by a statistically significant decrease in the detection frequency of the somatic dysfunctions at the regional and local levels. The median duration of standard orthopedic treatment also decreases (p<0,05).Conclusion. The obtained results demonstrate that the inclusion of osteopathic correction in the complex treatment of children in the first year of life with hip dysplasia shortens the treatment time for patients. It is recommended to continue research in this direction with a larger sample size.

Author(s):  
A. I. Khavkin ◽  
G. V. Volynets

Purpose of the study. Evaluation of the clinical efficacy of polymethylsiloxane polyhydrate (Enterosgel) in the complex treatment of children of the first year of life with diseases of the digestive system.Patients and methods. The authors carried out a retrospective analysis of the clinical course of diseases of the digestive organs of noninfectious etiology, the study included 38 patients of the first year of life (age 0.40 [0.25; 0.58] years; a continuousstudy of patients), who were treated with Enterosgel in the complex treatment. The comparison group consisted of 12 children (age 0.42 [0.25; 0.60] years) with diseases of the digestive organs, who did notreceive Enterosgel in complex treatment. The authors carried out a comparative assessment of the symptoms of intoxication, the nature of the stool, indicators of clinical blood tests and length of stay in the hospital.Results. The patients treated with Enterosgel demonstrated faster relief of intoxication symptoms and stool normalization; the length of hospital stay decreased 2 times, negative changes in blood tests and side effects of the drug were not observed.Conclusion. Complex treatment with Enterosgel of the diseases of the digestive organs in children of the first year of life is accompanied by more rapid relief of pathological symptoms and it reduces stay in the hospital, it is not accompanied by side effects, allowing us to recommend Enterosgel for the complex treatment of children of the first year of life.


Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 523
Author(s):  
Rosa Estela Gazeta ◽  
Ana Paula Antunes Pascalicchio Bertozzi ◽  
Rita de Cássia de Aguirre Bernardes Dezena ◽  
Andrea Cristina Botelho Silva ◽  
Thamirys Cosmo Gillo Fajardo ◽  
...  

Congenital Zika virus (ZIKV) infection may present with a broad spectrum of clinical manifestations. Some sequelae, particularly neurodevelopmental problems, may have a later onset. We conducted a prospective cohort study of 799 high-risk pregnant women who were followed up until delivery. Eighty-three women and/or newborns were considered ZIKV exposed and/or infected. Laboratory diagnosis was made by polymerase chain reaction in the pregnant mothers and their respective newborns, as well as Dengue virus, Chikungunya virus, and ZIKV serology. Serology for toxoplasmosis, rubella, cytomegalovirus, herpes simplex virus, and syphilis infections were also performed in microcephalic newborns. The newborns included in the study were followed up until their third birthday. Developmental delay was observed in nine patients (13.2%): mild cognitive delay in three patients, speech delay in three patients, autism spectrum disorder in two patients, and severe neurological abnormalities in one microcephalic patient; sensorineural hearing loss, three patients and dysphagia, six patients. Microcephaly due to ZIKV occurred in three patients (3.6%). Clinical manifestations can appear after the first year of life in children infected/exposed to ZIKV, emphasizing the need for long-term follow-up.


2010 ◽  
Vol 23 (01) ◽  
pp. 19-27 ◽  
Author(s):  
A. Volta ◽  
J. P. Morgan ◽  
M. Bonazzi ◽  
S. Manfredi ◽  
E. Bottarelli ◽  
...  

Summary Objectives: To evaluate distinctive features of pelvis and hip joint development of English Bulldogs throughout the first year of life. Methods: The pelves of 20 English Bulldogs were radiographed at three different ages (<4, 6–8, and 12–14 months). At each time point, the dogs were clinically evaluated and the abnormal hip joints were classified as mild, moderate, or severely deformed. The pelves were compared to a phantom study in which external rotation of a normal hemipelvis around its long axis was artificially created at different degrees, with different pelvic inclinations, and classified as either normal and without deformity, or as mild, moderate, or severely deformed. Hip joints and pelvic scores were statistically compared. Results: Although none of the dogs were considered lame at the end of the study, none of the hips showed normal development; 77.5% were moderately to severely deformed at 12–14 months of age. At this age, 75% of the hemipelves had moderate to severe torsional deformity (>5.2° of external rotation), with retroversion of the acetabulum confirmed by the presence of the crossover sign. An external rotation of the hemipelvis on its long axis >5° was likely associated with a moderate to severely altered hip joint conformation. Clinical Significance: Abnormal hip conformation was common in this series of English Bulldogs. Torsional deformity of the pelves with acetabular retroversion was a common and distinctive feature, which has not yet been thoroughly studied in dogs. These findings need further evaluation in English Bulldogs as well as in other breeds.


2017 ◽  
Vol 8 (2) ◽  
pp. 99-104
Author(s):  
Mariia E Turkunova ◽  
Liliya V Ditkovskaya ◽  
Evgenii N Suspitsin ◽  
Ludmila V Tyrtova ◽  
Ludmila A Jelenina ◽  
...  

This disease is characterized by the onset of primary immunodeficiency, which expresses itself as autoimmune multisystem failure, often clinically manifests during the first year of life; there are only about 150 cases in the world described by now. IPEX syndrome is caused by FOXP3 gene defect, which is a transcription factor that affects the activity of regulatory T-cells responsible for the maintenance of aytotolerance. There are around 70 pathogenic mutations in this gene described so far. Most patients with IPEX-syndrome have a clinical manifestations of the disease in the early neonatal period or during the first 3-4 months of life. For this disease the following clinical triad of manifestations is typical: Autoimmune enteropathy (100%), diabetes mellitus (70%), skin lesions (65%), as in the syndrome structure includes severe developmental delay (50%), thyroid disease (30%), recurrent infections (20%), rarer autoimmune cytopenia (Coombs-positive hemolytic anemia), pneumonia, nephritis, hepatitis, artrit, myositis, alopecia. However, some cases of later manifestations were described (in patients of more than 1 year of age) when patients did not show all clinical and laboratory symptoms typical for severe forms of the disease. Due to the severity of the disease and the high mortality in this group of patients, it is very important to diagnose it early and start therapy timely. The article describes a clinical case of permanent neonatal diabetes mellitus in the structure of IPEX syndrome.


2012 ◽  
Vol 58 (2) ◽  
pp. 3-9 ◽  
Author(s):  
M A Melikian ◽  
M A Kareva ◽  
E E Petriaĭkina ◽  
I É Volkov ◽  
Iu V Aver'ianova ◽  
...  

Congenital hyperinsulinism (CHI) is a most frequent cause of persistent hypoglycemia in the children during the first year of life. This pathology is biochemically characterized by inadequate secretion of insulin by beta-cells of the pancreas. Congenital hyperinsulinism is a highly heterogeneous condition in terms of clinical manifestations, histological features, and molecular-genetic defects underlying the development of this disorder. A total of 9 genes are known to be involved in pathogenesis of CHI. The majority of the cases (40-60%) are attributable to the defects in KCNJ11 and ABCC8 genes encoding for the ATP-dependent potassium channels in the pancreatic cells. Approximately 15-20% cases are associated with the mutations of GCK and GLUD1 genes participating in the regulation of intracellular glucose metabolism. The results of clinical, hormonal, molecular-genetic, and histological examination of 42 children presenting with congenital hyperinsulinism are reported. These data were used to analyse the genotype-phenotype relationships.


2001 ◽  
Vol 87 (6) ◽  
pp. 436-438 ◽  
Author(s):  
Bilgehan Yalçin ◽  
Gürsel Leblebicioğlu ◽  
Elif Güler ◽  
Gökhan Gedikoğlu ◽  
M Tezer Kutluk

Congenital/infantile fibrosarcoma occurs frequently in the first year of life and differs from fibrosarcoma in adulthood. The clinical course of congenital/infantile fibrosarcoma is more favorable and metastatic spread is rare. While adult fibrosarcomas are common in the thigh, congenital/infantile fibrosarcomas affect chiefly the distal portions of the extremities. Standard treatment is primarily wide surgical excision. Chemotherapy may be given as neoadjuvant or adjuvant treatment in order to avoid the morbidity associated with wide excision. In this case report we present our experience of a newborn affected by congenital/infantile fibrosarcoma of the left thigh.


PEDIATRICS ◽  
1985 ◽  
Vol 76 (6) ◽  
pp. 973-975
Author(s):  
D. W. HIDE ◽  
B. M. GUYER

Studies of the influence of the initial feeding method upon the development of allergic disease have produced widely conflicting results.1 Unfortunately, the major social factors that lead a mother to choose to bottle-feed, rather than breast-feed, her infant have been ignored so that breast- and bottle-fed infants tend to be highly selected groups that cannot be directly compared unless many other variables are also taken into account. The Isle of Wight Infant Feeding Survey was established to study the development of allergic disease in childhood in an entire infant population. The results of the study in the first year of life have been reported.2,3


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