scholarly journals The role of hope in patients' use of cancer-related coping strategies

Author(s):  
Jenna J Belanger

Cancer patient's initial appraisal of the disease (i.e., as a threat, harm, or challenge), as well as their level of hope, has been linked to patients' coping strategies (i.e. approach or avoidance coping). However, it is unclear whether the well-established relationship between primary appraisals and coping in moderated by cancer patients' levels of hope. To determine if hope moderated this realationship, colorectal cancer patients (N=122) completed measures of appraisals and hope following their diagnosis and a measure of coping six-months later. Results indicated that patients appraised cancer as more of a challenge than a threat reported high levels of baseline hope. both challenge appraisals and baseline higher hope predicted approach coming six months later, however, hope did not moderate the relationship between appraisals and coping. This study highlights may of the conceptual, design, and psychometric problems present when measuring appraisals, hope, and coping among cancer patients.

2021 ◽  
Author(s):  
Jenna J Belanger

Cancer patient's initial appraisal of the disease (i.e., as a threat, harm, or challenge), as well as their level of hope, has been linked to patients' coping strategies (i.e. approach or avoidance coping). However, it is unclear whether the well-established relationship between primary appraisals and coping in moderated by cancer patients' levels of hope. To determine if hope moderated this realationship, colorectal cancer patients (N=122) completed measures of appraisals and hope following their diagnosis and a measure of coping six-months later. Results indicated that patients appraised cancer as more of a challenge than a threat reported high levels of baseline hope. both challenge appraisals and baseline higher hope predicted approach coming six months later, however, hope did not moderate the relationship between appraisals and coping. This study highlights may of the conceptual, design, and psychometric problems present when measuring appraisals, hope, and coping among cancer patients.


2016 ◽  
Vol 2 ◽  
pp. 96-103 ◽  
Author(s):  
Aleksandra I. Czerw ◽  
Urszula Religioni ◽  
Andrzej Deptała ◽  
Bożena Walewska-Zielecka

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Katarzyna Walkiewicz ◽  
Joanna Strzelczyk ◽  
Dariusz Waniczek ◽  
Krzysztof Biernacki ◽  
Małgorzata Muc-Wierzgoń ◽  
...  

Colorectal cancer is one of the most common cancers in the world. Due to its still undetermined pathogenesis, we are searching for signaling pathways that are important in the development of colorectal cancer. In this article, we present results of study on the role of ADAM proteins in colorectal cancer. The study included 85 adult colorectal cancer patients (48 men, 37 women) and 25 patients in the control group (after diagnostic colonoscopy—without cancer). During hospitalization, a serum sample (3 cm3) was collected from the study and control group, anthropometric measurements were conducted and others clinical data were analyzed. In the serum ADAM10, 12, 17, and 28, protein concentrations were determined and, in the next step, examined the relationship between ADAMs concentrations and selected clinical parameters in both groups. The analysis showed that serum levels of ADAM10 and ADAM28 are significantly higher in patients with colorectal cancer and correlate with histopathological grading and with presence of distant metastases. Moreover, noticed the trend to correlate concentrations of adamalysines with higher BMI score. One of the functions of adamalysines is the activation of growth factors involved in cancer, including IGF and TNFα. The increased activity of adamalysines in patients may play a role in the pathogenesis of colorectal cancer. Our study highlights the prevalence of metabolic disorders in the group of patients with diagnosed CRC, and this cancer seems to be a further complication of obesity.


Surgery ◽  
2019 ◽  
Vol 165 (2) ◽  
pp. 461-468 ◽  
Author(s):  
Jonathan S. Abelson ◽  
Alanna Chait ◽  
Megan Johnson Shen ◽  
Mary Charlson ◽  
Anna Dickerman ◽  
...  

2019 ◽  
Vol 121 ◽  
pp. 81-87 ◽  
Author(s):  
Yilong Yang ◽  
Guangwei Sun ◽  
Xiaomei Dong ◽  
Huijie Zhang ◽  
Chengzhong Xing ◽  
...  

2014 ◽  
Vol 29 (1) ◽  
pp. e30-e39 ◽  
Author(s):  
Ariel Zwenger ◽  
Martin Rabassa ◽  
Sandra Demichelis ◽  
Gabriel Grossman ◽  
Amada Segal-Eiras ◽  
...  

Aim Colorectal cancer (CRC) is one of the most prevalent malignancies in Argentina with 11,043 new cases and 6,596 deaths estimated to have occurred in 2008. The present study was developed to clarify the differential expression of MUC1, MUC2, sLex, and sLea in colorectal cancer patients and their relationship with survival and clinical and histological features. Methods Ninety primary tumor samples and 43 metastatic lymph nodes from CRC patients were studied; follow-up was documented. Twenty-six adenoma and 68 histological normal mucosa specimens were analyzed. An immunohistochemical approach was applied and statistical analysis was performed. Results In tumor samples, MUC1, sLea, and sLex were highly expressed (94%, 67%, and 91%, respectively); also, we found a significantly increased expression of the 3 antigens in primary tumors and metastatic lymph nodes compared with normal mucosa and adenomas. MUC2 was expressed in 52% of both normal mucosa and CRC samples; this reactivity significantly decreased in metastatic lymph nodes (p<0.05). A multiple comparison analysis showed that MUC1 and sLex discriminated among 3 groups: normal, adenoma, and CRC tissues. The increase of sLex expression showed an association with recurrence, and survival analysis showed that a high sLex staining was significantly associated with a poor survival. By multivariate analysis MUC1 inmunoreactivity correlated positively and significantly with tumor size, while MUC2 expression showed the opposite correlation. Conclusions The correlation of sLex overexpression in primary tumors and metastatic lymph nodes, the discrimination among the normal, adenoma, and CRC groups based on sLex expression, as well as its association with recurrence and survival, all suggest a prognostic role of sLex in Argentinian CRC patients.


Sign in / Sign up

Export Citation Format

Share Document