scholarly journals Pemberian Madu Pada Klien Diare Dengan Masalah Keperawatan Peningkatan Frekuensi BAB Di Desa Rajabasa Lama Lampung Timur

2021 ◽  
Vol 4 (5) ◽  
pp. 1196-1201
Author(s):  
Intan Putri ◽  
Setiawati Setiawati
Keyword(s):  
Antibacterial Activity ◽  
Traditional Medicine ◽  
Nursing Care ◽  
Endemic Disease ◽  
Ancient Times ◽  
Anti Inflammatory

ABSTRAK Diare di Indonesia merupakan penyakit endemis dan juga merupakan penyakit potensial Kejadian Luar Biasa (KLB) yang sering disertai dengan kematian. Angka kejadian diare Provinsi Lampung khususnya di Lampung Timur yaitu 21.588 kasus. Madu sebagai obat tradisional dengan berjuta khasiat sudah dikenal sejak zaman dahulu, bahkan Al-Quran menjelaskan manfaat lebah dan produknya sebagai penyembuh berbagai macam penyakit. Termasuk salah satunya diare. Madu adalah agen non alergi, nutrisi alami yang tinggi nilai antioksidan, anti-inflamasi, dan memiliki aktivitas antibakteri. Tujuan penelitian, untuk mendapatkan pengalaman dan kompetensi lebih dalam pemberian asuhan keperawatan komprehensif pemberian madu terhadap penurunan frekuensi bab. Adapun intervensi yang dilakukan dengan pemberian madu 1 sdm dengan dilarutkan kedalam air 100 cc selama 5 hari diminum secara rutin 3 kali sehari.  Terdapat penurunan frekuensi bab setelah diberikan madu pada anak diare. Dengan demikian pemberian madu pada anak diare untuk menurunkan frekuensi buang air besar sangat efektif. Kata Kunci: Diare, Madu, Nutrisi ABSTRACTDiarrhea in Indonesia is an endemic disease and is also a potential disease of Extraordinary Events (KLB) which is often accompanied by death. The incidence of diarrhea in Lampung Province, especially in East Lampung is 21,588 cases. Honey as a traditional medicine with millions of benefits has been known since ancient times, even the Koran explains the benefits of bees and their products as a cure for various diseases. Including one of them diarrhea. Honey is a non-allergic agent, a natural nutrient that is high in antioxidant value, anti-inflammatory, and has antibacterial activity. The aim of the study was to gain more experience and competence in the provision of comprehensive nursing care for honey to reduce chapter frequency. The interventions were carried out by giving 1 tablespoon honey dissolved into 100 cc of water for 5 days drink routinely 3 times a day. There is a decrease in the frequency of chapters after giving honey to children with diarrhea. Thus giving honey to children with diarrhea to reduce the frequency of chapters is very effective.  Keywords: diarrhea, honey, nutrient

scholarly journals Therapeutic Hydrogel Lenses and the Antibacterial and Antibiotic Drugs Release

2021 ◽  
Vol 11 (4) ◽  
pp. 1931
Author(s):  
Alessandra Pulliero ◽  
Aldo Profumo ◽  
Camillo Rosano ◽  
Alberto Izzotti ◽  
Sergio Claudio Saccà
Keyword(s):  
Antibacterial Activity ◽  
Salmonella Typhimurium ◽  
Drug Availability ◽  
Silicone Hydrogel ◽  
Antibiotic Drugs ◽  
Medical Approach ◽  
Anti Inflammatory ◽  
Gradient Hplc

The aim of this research was to evaluate the effects of different lens types on the availability and efficacy of anti-inflammatory and antibiotic drugs. Three lens types were examined: (1) nonionic hydrogel lenses; (2) ionic hydrogel lenses; and (3) silicone hydrogel lenses. The lenses were incubated with (a) dexamethasone; (b) betamethasone; (c) bromophenacyl bromide; and (d) chloramphenicol. Drug availability was quantified by gradient HPLC, and chloramphenicol antibacterial activity was quantified by testing the inhibition of Salmonella typhimurium growth on agar. The lens allowing the most abundant passage of betamethasone was the ionic hydrogel lens, followed by the silicone hydrogel lens and nonionic hydrogel lens. The lens allowing the most abundant passage of dexamethasone was the ionic hydrogel lens, but only at 0.5 h and 1 h. Regarding chloramphenicol, the ionic hydrogel lens and silicone hydrogel lens allowed more abundant passage than the nonionic hydrogel lens. These results highlight the relevance of adapting lenses to anti-inflammatory therapy, thus allowing a personalized medical approach.

Capping of silver nanoparticles by anti-inflammatory ligands: Antibacterial activity and superoxide anion generation

2019 ◽  
Vol 193 ◽  
pp. 100-108 ◽  
Author(s):  
Manuel I. Azócar ◽  
Romina Alarcón ◽  
Antonio Castillo ◽  
Jenny M. Blamey ◽  
Mariana Walter ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Superoxide Anion ◽  
Superoxide Anion Generation ◽  
Anti Inflammatory

scholarly journals An Overview of the Various Uses of Ephedra distachyaL. from the Past to the Present

2020 ◽  
Vol 1 (2) ◽  
pp. 82-86
Author(s):  
Mansureh Ghavam ◽  
Zeinab Soleimaninejad
Keyword(s):  
Medicinal Plants ◽  
Traditional Medicine ◽  
Scientific Evidence ◽  
Experimental Studies ◽  
Trial And Error ◽  
Traditional Medicines ◽  
Beneficial Effects ◽  
Ephedra Distachya ◽  
Ancient Times ◽  
Review Study

Background: Nowadays, many people believe in traditional medicines and use them for different diseases. Knowledge of medicinal plants and traditional medicine has been practiced for centuries through trial and error, and many important treatments for the disease have been passed down from one generation to the next. Ephedra is a valuable plant and has been used to treat diseases since ancient times. Accordingly, this study aims to comprehensively introduce Ephedra distachya L. in traditional medicine. Methods: In this review study, databases such as Google Scholar, SID, Scopus, and books on medicinal plants in Persian and English languages were searched to collect data. The keywords included "ephedra", "traditional medicine", "goat’s beard", and "medicinal plants". Results: Many resources highlighted the importance of using ephedra due to its useful properties. Experimental studies in traditional medicine show the effect of this plant in the prevention of diseases, such as asthma and bronchitis. Conclusion: Considering the beneficial effects of ephedra and scientific evidence about its effects, further studies are needed to better understand the use of this plant in traditional medicine.

scholarly journals DELONIX REGIA BOJ. EX. HOOK RAFFIN; FAMILY: FABACEAE, BARK METHANOL EXTRACT PHYTOCHEMICAL PROFILE AND POTENTIAL THERAPEUTIC EVALUATION

2020 ◽  
pp. 100-105
Author(s):  
ARPITHA SHIVAMALLU ◽  
SHAILASREE SEKHAR
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Methanol Extract ◽  
Laser Scanning Microscopy ◽  
Charge Ratio ◽  
Delonix Regia ◽  
Human Pathogenic Bacteria ◽  
Cox 2 ◽  
Anti Inflammatory ◽  
Mcf 7

Objectives: The aim of this study was to evaluate the antioxidant, anti-inflammatory, and anti-cancer potencies of the Delonix regia bark, a first of its kind. Methods: The bark was extracted sequentially in Soxhlet apparatus with hexane, chloroform, and methanol in the increasing order of polarity. These extracts were subjected to find its antioxidant activity and total phenol content. Antibacterial activity against human pathogenic bacteria was tested. The anti-inflammatory properties were elucidated by its capacity to inhibit 15-lipoxygenase (LOX) and human cyclooxygenase (COX)-2. Cell cytotoxic capacity was evaluated against MCF-7 cells breast cancer cell lines. Results: Liquid chromatography (LC)-Mass Spectroscopy (MS) fingerprint of the methanol extract identified a total of 14 polyphenols, of which five were structurally characterized based on their mass-charge ratio [M-H]− peak, UV-vis absorption in comparison to published data. Antibacterial activity by disk diffusion inhibited human pathogenic bacteria. Bacterial biofilm inhibition capacity of extract (750 mg) imaged by confocal laser scanning microscopy revealed loss of microcolonies. Extract when tested for 15-LOX inhibition exhibited IC50 values of 94.5 ± 1.23 mg.mL−1 by enzyme kinetics studies using spectrophotometric techniques. Similarly, it could inhibit COX-2 enzyme at relatively lower concentrations (32.18 ± 1.91 mg.mL−1). Further, it quenched free radicals produced by Fentons’ reagent studied by DNS-nicking assay indicating its strong antioxidant property with the capacity to protect DNA. In vitro cytotoxicity was evaluated by 3-(4,5-dimethylthylthiazol-2-yl)-2,5-diphynyl tetrazolium bromide assay and apoptosis induced in MCF-7 cells was assessed morphologically. Conclusion: Our data suggest that D. regia bark methanol extract exerts its therapeutic activity for further pharmaceutical evaluations. Further studies are necessary to determine the mechanisms of these pharmacological properties.

scholarly journals Evaluation of analgesic and anti-inflammatory activities of Warionia saharae essential oil

2021 ◽  
pp. 1-10
Author(s):  
Mimouna Yakoubi ◽  
Nasser Belboukhari ◽  
Khaled Sekkoum ◽  
Mohammed Bouchekara ◽  
Hassan Y. Aboul-Enein
Keyword(s):  
Essential Oil ◽  
Traditional Medicine ◽  
Analgesic Activity ◽  
Inflammatory Diseases ◽  
Hot Plate ◽  
Hot Plate Test ◽  
Standard Drug ◽  
Analgesic Effects ◽  
Test Models ◽  
Anti Inflammatory

Warionia saharae Benth & Coss (W.s) (Asteraceae) is a monospecific genus endemic to Algeria and Morocco. Its leaves are used in their traditional medicine, such as gastrointestinal and inflammatory diseases; for instance, rheumatoid arthritis treatment. In this work, our team investigated the anti-inflammatory and analgesic effects of essential oil extracted from the dried upper parts of Warionia saharae based on different standard experimental test models. The analgesic activity was assessed by central and peripheral models, such as “hot plate” and “writhing” tests on Swiss albino mice. The hot plate test used latency measurements to assess acute cutaneous pain sensitivity, as a result; the latency of the hind-paw pain response was by licking and either shaking or jumping, those occurrences were recorded. Writhing test as a chemical method used to induce pain of peripheral origin in mice by injecting acetic acid intraperitoneally (IP). This results in characteristic stretching behavior of the animals (cramps and contortions). The evaluation of the analgesic activity, shows that the essential oil of this plant induces a decrease in the number of abdominal cramps in the contortion test and a maximum inhibition of pain. As for the anti-inflammatory effect, it was studied by the “paw edema” test, a phlogogenic agent (formaldehyde) was used to stimulate inflammation in the paws of mice. Anti-inflammatory properties can be observed by inhibiting this edema compared to the standard drug Diclofenac. In conclusion, Warionia saharae essential oil (75 mg/kg) showed a strong anti-inflammatory and analgesic activities which supports the conventional use of this plant in traditional medicine.

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