Persistence Detection of Sars-Cov-2 RNA in Healthcare Workers with COVID-19: A Case Report

2020 ◽  
Vol 2 (3) ◽  
pp. 121-129
Author(s):  
Ilzy Jum Ahmad ◽  
Sostro Mulyo ◽  
Abdi Dzul Ikram Hasanuddin

Coronavirus Disease 2019 (Covid-19) has now become a concern around the world. Until 6 September 2020, there were 190,665 cases in Indonesia, and it was in the third rank of most cases in the Asian region. It is important to determine the criteria of return to work for healthcare workers with Covid-19 positive in Indonesia. This case report discussed a female patient, 32 years old with chief complaint of fever and itchy throat since 2 days ago. She is a health care worker in the hospital, with a history of treating patients with positive confirmation of Covid-19 for 2 days in the ordinary ward before the case was confirmed with a history of contact approximately 5 days ago. The patient was diagnosed with positive confirmation of Covid-19 and was required for self-isolation. The patient still had positive results of RT-PCR Covid-19 up to the third examination in 30 days after the initial RT-PCR testing, although received specific antiviral treatment with oral oseltamivir and oral supplementation. Based on growing evidence that Sars-Cov-2 may not infectious for more than ten days in the mild-moderate disease, this case report is strengthening the use of symptom-based strategic approach to determine when to return to work in Indonesian healthcare workers with positive COVID-19.

Author(s):  
Kalyani P. Barde ◽  
Gautam S. Aher ◽  
Urmila G. Gavali

Chorioangioma is the term used to describe an abnormal proliferation of vessels arising from chorionic tissue, which is most commonly observed in the third, and less frequently in the second trimester of pregnancy as a solitary nodule or, less commonly, as multiple nodules. We here report a case of placental chorioangioma which presented as a case of preterm labour. 21 year old primigravida presented to us at 26 weeks of gestation with history of PV leak and pain in abdomen. Ultrasound showed a single live foetus corresponding to 24-26 weeks of gestation with amniotic fluid index (AFI): 5 cm (oligohydramnios) there was evidence of 58×42 mm heterogeneously hypoechoic lesion noted over placenta likely s/o chorioangioma. Patient went into spontaneous preterm labour on day 5 and delivered vaginally. Placenta weighted 700 gm. A globular mass of size 6×7 cm was attached to foetal surface of placenta with a pedicle with confirmed the finding of ultrasonography. Placental chorioangioma is associated with high rates of perinatal complications. Most complications may appear early and delivery is problematic due to prematurity. Thus better prenatal investigations and regular follow up is required for early diagnosis and treatment.


2021 ◽  
Vol 22 (1) ◽  
pp. 85-89
Author(s):  
V. Р. Kovalyk ◽  
V. V. Malinovskaya ◽  
A. N. Shuvalov ◽  
L. F. Kurilo ◽  
К. I. Yurlov ◽  
...  

Objectives. To present a case report of male infertility associated with cytomegalovirus infection and the outcome of antiviral treatment.Clinical observation. A 31-year-old man presented with a history of 6 years of infertility. No pathology was revealed in his wife. High loads of cytomegalovirus (CMV) were detected by PCR: in expressed prostatic secretion (EPS)  8700 copies/ml, in ejaculate – 598 440 copies/ml. Sperm examination revealed necrozoospermia and leukospermia. CMV-associated accessory gland infection was verified. The patient was treated with valacyclovir 500 bid for 90 days and interferon α2β suppository (Viferon®) 1 million IU for 30 days. All sperm parameters improved in 1 month after initiation of antiviral treatment. Sperm concentration and motility increased × 1.5 and × 1.4 respectively, sperm viability and leukocyte count achieved reference values.  At the same time, CMV loads decreased: EPS to 300 copies/ml, the ejaculate to 54 000 copies/ml. After 3 months  (by the end of the antiviral treatment): EPS-negative, the ejaculate – 6060 copies/ml; after 6 months: EPS – negative, the ejaculate 3900 copies/ml. Within 6 months, the woman became pregnant and gave birth to a healthy baby girl. After 3 years, there was a second pregnancy and the birth of a healthy boy.Conclusion. The male factor has been established as the cause of infertility in a married couple; the only probable etiological agent of pathozoospermia was cytomegalovirus infection. The use of complex antiviral and immunotherapy (interferon α2β with antioxidants, Viferon®) provided positive dynamics in clinical, sperm and laboratory parameters, which led to the conception and birth of two children. 


2021 ◽  
Vol 2 (1) ◽  
pp. 24-27
Author(s):  
Amita Rai ◽  
Bandana Koirala ◽  
Mamta Dali ◽  
Sneha Shrestha ◽  
Ashish Shrestha

Pyogenic granuloma is a benign inflammatory hyperplasia of connective tissue. It depicts an overzealous tissue response to a known stimulus or injury and is commonly found in the gingiva, especially in the anterior maxilla, and rarely on lips, oral mucosa, and tongue. It is commonly seen during the second, third, and fourth decade in females, with predilection in the third decade. This case report depicts the unusual presentation of pyogenic granuloma of the lower lip in an 11-year-old male child following a positive history of trauma and lip biting, which was successfully managed by excision under local anesthesia.


2021 ◽  
Vol 104 (7) ◽  
pp. 1214-1217

The authors report a case of a 32-year-old Thai woman with a COVID-19 infection that presented with urticaria and angioedema with a pityriasis rosea (PR)-like rash at a private hospital in Thailand. She presented at the hospital with bloody nasal discharge and diarrhea but without fever, myalgia, or any respiratory symptoms. She complained of angioedema and PR-like lesions on the third day of the treatment. Urticarial rash appeared intermittently for four weeks after all medications were discontinued, during which the patient had no fever, no respiratory symptoms, or any other symptoms. However, the RT-PCR results for COVID-19 RNA were positive during the time that the urticarial symptoms persisted. The COVID-19 RNA became negative on the fourth day after the last urticarial episode. Urticarial rash may be a clue that the inflammatory process is activated by COVID-19 virus after the treatment is completed. Keywords: Cutaneous; Pityriasis rosea; Angioedema; Urticaria; COVID-19


2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Li Lu ◽  
Peter A. Drew ◽  
Anthony T. Yachnis

Hemangioblastoma primarily occurs in the CNS, most commonly in the posterior fossa. Extracranial locations are less common, and metastatic tumor involving the lung is exceedingly rare with only three cases previously reported. Two were autopsy studies in patients who died of complications of the CNS hemangioblastomas in 1943 and 1981, and the third was mentioned in a case report addendum providing follow-up information on hepatic hemangioblastoma in 1991. We report a case of a 48-year-old man who presented with multiple lung nodules treated by surgical excision. Pathological study revealed features classic for hemangioblastoma. The patient had a remote history of hemangioblastomas having been excised from the posterior fossa 7 and 20 years previously. This report details a fourth case of metastatic pulmonary hemangioblastoma. It is the first report on surgically resected hemangioblastomas from the lung of a living patient with histological and immunohistochemical characterization.


2020 ◽  
pp. 112067212094628 ◽  
Author(s):  
Zeynep Kayaarasi Ozturker

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus causing an ongoing pandemic in 2020. Although the symptomatic patients infected by SARS-CoV-2 generally show respiratory distress, atypical manifestations such as conjunctivitis are also observed. A series of cases are reported in which reverse transcriptase polymerase chain reaction (RT-PCR) testing on tears had demonstrated the presence of the virus. However, the transmission of the virus through ocular fluids remains unknown. Case description: In this case report, the development of conjunctivitis is presented as the sole symptom of a new coronavirus disease 2019 (COVID-19) in an emergency health care worker. The patient’s first application was to the ophthalmology clinic due to redness, stinging, tearing, and photophobia for one day in the right eye. The patient had no symptoms of fever, cough, shortness of breath, or fatigue. Two days later, the RT-PCR test, blood analysis, and chest computed tomography (CT) were applied to the patient for being in contact with a COVID positive patient. Conjunctival swabs did not identify SARS-CoV-2 by RT-PCR. However, nasopharyngeal swab and blood test confirmed the diagnosis of COVID-19. Chest CT did not show pneumonia. Conclusion: This phenomenon shows that conjunctivitis may occur as a sole manifestation of COVID-19 which needs to be carefully evaluated by health care workers and eye care professionals during the pandemic.


2003 ◽  
Vol 45 (3) ◽  
pp. 159-161 ◽  
Author(s):  
Julieta M. Paçô ◽  
Dulcinéia M.B. Campos ◽  
José Luiz de Barros Araújo

The authors report on a new case of human Bertiellosis in a 2-year old female patient who was born in Goiânia-Goiás (Brazil) and has had history of permanent dwelling in an area frequently visited by simians in Mato Grosso (Brazil). At the time of diagnosis the patient showed inappetence, abdominal pain, and loss of weight. Eggs and proglottids were found in her stool and were identified as Bertiella sp. The objective of this report is to register the third case of human Bertiellosis in Brazil, characterizing one more case of helminthic zoonosis.


2021 ◽  
Vol 12 (3) ◽  
pp. 730-732
Author(s):  
Anshul Chauhan ◽  
Meenakshi Malik ◽  
Ashish Mehta

COVID-19 has affected negatively day to day life and global economy. Considering need for search of immunity modulator drugs for fighting this virus, Ayurvedic treatment was planned. 30 year old female patient, having history of the hypertension was diagnosed as a case of COVID-19 through RT-PCR. AYUSH Kwath (20 ml OD for 7 days), Sanshamani vati(2BD for 7 days), Sudarshan churn (3gm for14 days), Vit –C and Azithromycin given orally for 5 days. RT-PCR sample result was found COVID negative on 7th day of treatment. Antipyretic, anti-inflammatory, immune-modulatory activities were documented earlier of used medications which have shown beneficial result in present case also. Orally administered, add on Ayurvedic formulation exerted symptomatic relief in symptomatic COVID-19 case with pitta-kapha prakriti having co-morbidity of Hypertension. RCT needs to be conducted to validate result in larger sample which will generate evidence for support.


Author(s):  
Jonathan Dalavina ◽  
Bruno Fernandes Costa Ferreira ◽  
Camila Vitelli Molinari ◽  
Vivian Bertoni Xavier ◽  
Vera Lúcia Dos Santos Alves

         Introdução: A pandemia da COVID-19 gerou a necessidade do estudo de medidas que possam alterar a evolução da doença, principalmente na internação hospitalar com o paciente que apresenta sinais de insuficiência respiratória e alteração da oxigenação que classifica a gravidade dos pacientes e a posição PRONA pode tornar-se um recurso indicado. Objetivo: Apresentar uma experiência de utilização da posição PRONA intermitente em paciente sem o suporte ventilatório invasivo com diagnóstico de COVID-19 sob internação hospitalar. Relato de Caso: Homem de 49 anos, com COVID-19, antecedente de asma controlada, com três dias de sintomas, que foi internado devido à piora clínica com evolução grave nos primeiros seis dias de internação. Foi indicada a utilização da PRONA a partir do terceiro dia. O paciente adotou o recurso espontaneamente com aumento progressivo e referia se posicionar devido à percepção de melhora do desconforto respiratório. As imagens radiográficas de tórax, uso de oxigenoterapia em alta concentração e o cálculo da PaO2 /FiO2 demonstraram que o paciente era de extrema gravidade. Após 17 dias de uso da PRONA o paciente recebeu alta, sem dependência de oxigênio, independente e sem complicações relacionadas ao posicionamento. Conclusão: A posição PRONA mostrou-se como alternativa possível, promissora, de baixo custo e risco, com sucesso para este paciente que recebeu alta hospitalar sem o uso de oxigenoterapia.Palavras-chave: Infecções por coronavirus, Decúbito ventral, Respiração, Fisioterapia, Pneumonia ABSTRACTIntroduction: The pandemic of COVID-19 developed the need to study measures that can change the evolution of the disease, especially in hospitalization with the patient who shows signs of respiratory failure. This happened because the alteration of oxygenation classifies the severity of patients made the prone position an indicated resource. Objective: To present an experience of using the intermittent prone position in a patient without invasive ventilatory support diagnosed with COVID-19 during hospitalization. Case Report: A 49-year-old man with COVID-19, with history of controlled asthma, with three days of symptoms, who was hospitalized due to clinical worsening with severe evolution in six days initially of hospitalization. The use of the prone was indicated in the third day. Afterwards, the patient spontaneously adopted the resource with progressive increase and referred to position himself due to the perception of improvement in respiratory distress. Radiographic images of the chest, use of oxygen in high concentration and the calculation of PaO2 / FiO2 demonstrated that the patient was extremely serious. After 17 days, the patient was discharged, without oxygen dependence, independently and without complications related to positioning. Conclusion: The prone position proved to be a possible, promising, low cost and risky alternative, successfully for this patient who was discharged from the hospital without the use of oxygen therapy.Keyworks: Coronavirus infections, Prone position, Respiration, Physical therapy specialty, Pneumonia


2010 ◽  
Vol 4 (4) ◽  
pp. 353-355 ◽  
Author(s):  
Melissa Castello Branco e Silva ◽  
Sonia Maria Dozzi Brucki

Abstract We report a case of a 43-year-old woman with brainstem encephalitis in the third trimester of pregnancy. She presented complex visual and auditory hallucinations in the acute disease phase (hearing opera arias and seeing room furniture upside-down). Hallucinations resolved with antiviral treatment.


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