scholarly journals Assessment of Inter-Connection between Suriphobia and Individual’s Blood Glucose Level: A Questionnaire Centred Project

2019 ◽  
Vol 4 (1) ◽  

Blood sugar level is actually the estimation of the total glucose sugar content in the one’s blood. Insulin and Glucagon are the two key hormones responsible for maintaining homeostasis which sustain blood glucose level. Hypoglycemia and Hyperglycemia are the two conditions associated with blood sugar level. In case of hypoglycemia, blood glucose level falls below the normal level of glucose in the blood while hyperglycemia is the condition of elevated blood glucose level than the normal range. Different tests are available to test the blood glucose level of an individual. The central objective of this project was to assess the inter-connection between one’s being suriphobic and their blood sugar level at fasting. Phobia is a word associated with the condition of extreme fear from a series of specified events. Suriphobia or mice fear is the term used for those individuals who extremely fear from mice, rats, rodents etc. This study was a questionnaire based project to assess the fact that if there is any inter-connection between people’s being suriphobic and their blood glucose level at fasting. For this purpose blood sugar level of the sample population was calculated using Glucometer. Statistical Analysis point towards the significant results if this study as the calculated p-value was exact of the standard p¬-value which is p ≤ 0.05. Therefore, the fact that there is a significant relation between individual’s being Suriphobe and their Blood Glucose Level at fasting is proved.

Author(s):  
Soni .

Background: Diabetes increases the risk of macrovascular complications and is often associated with angina in patient. Currently nicorandil, a potassium channel opener is being frequently used for the prevention and long-term treatment of angina pectoris. Glibenclamide exerts its antidiabetic action by closing the ATP sensitive potassium channels. Simultaneous use of nicorandil may antagonizes this action and may worsens the existing diabetes. To evaluate the pharmacodynamic interaction present study has been taken to study the effect of Nicorandil, a potassium channel opener on blood glucose level of alloxan induced diabetic rats and its pharmacodynamics interaction with Glibenclamide.Methods: Albino rats, weighing 150-200gm of male sex were used for the study. Diabetes was induced by injecting alloxan monohydrate 2% solution intra peritoneally in a dose of 150mg/kg body weight. Animal with Fasting Blood Sugar level between 250-300g/dl was selected for study and they were divided into 4 groups of 5 animals each. Group I- serving as control received 0.5ml normal saline orally for 28 days. Group II was given glibenclamide (0.5mg/kg body wt) for 28 days. Group III was treated orally with nicorandil (0.3mg/kg body wt) for 28 days. Group IV was given glibenclamide (0.5mg/kg) and nicorandil (0.3mg/kg) for 28 days. Fasting Blood Sugar level was recorded in all rats on 1st,3rd,7th,14th,21st and 28th day of the treatments.Results: results showed that glibenclamide significantly reduce blood sugar level (p <0.05) Wherase nicorandil showed rise in blood glucose level (p <0.05) While the combination (glibenclamide + nicorandil) showed rise in blood glucose (p <0.05) overall.Conclusions: Nicorandil worsen the existing diabetes and to be avoided or replaced with alternative drug in case of diabetes being treated with sulfonyl urease group of drugs.


Jurnal NERS ◽  
2020 ◽  
Vol 14 (2) ◽  
pp. 224
Author(s):  
Muflih Muflih ◽  
Suwarsi Suwarsi ◽  
Fajarina Lathu Asmarani

ABSTRACTIntroduction: The examination of patients with diabetes mellitus (DM) can be done by reviewing their complaints and through a capillary blood glucose level test to determine the value of their Random Blood Glucose Level. QRMA (Quantum Resonance Magnetic Analyzer) is claimed to be able to check the patient’s bodily condition (including blood glucose) with an accuracy of 85%. The purpose of this study was to verify the validity of the QRMA tool and its accuracy by comparing the results of the anamnesis and the examination conducted using the capillary blood glucose test method.Methods: The research method used was a cross-sectional design. The total sample consisted of 44 respondents in the working area of the Community Health Centers in Yogyakarta with the risk factor being blood sugar level instability. The sampling technique used was purposive sampling. The main variable in this study was the value of the blood sugar level measured based on the coefficient value of the QRMA tool and the value of Random Blood Glucose obtained through the capillary blood glucose test.Results: The blood glucose value was not correlated significantly with the coefficient value of QRMA. The value of blood glucose when examined alongside the result of the respondent's anamnesis showed there to be a significant difference. The value of the QRMA coefficient when examined against the results from the history of the respondents showed no significant difference. Linear regression showed that the variables of height, body weight, and IMT had a correlation with the QRMA coefficient value.Conclusion: The QRMA tool was not able to provide a picture of the actual condition of the blood glucose level of the respondents when compared with the results of the anamnesis and the blood glucose value from the capillary blood glucose test. Non-invasive health measurement devices such as QRMA are not used by nurses as a standard for determining the health status of DM patients.


2019 ◽  
Vol 4 (1) ◽  

The target of the existing study was to relate chicken likeness with blood glucose level. Blood glucose level or blood sugar level or blood sugar level concentration is the level of the glucose existing in the blood of homo sapiens and mammals. Sum total of 100 students participate in the current research. We made a question sheet and got access to the blood sugar level of the participants. The participants were the students of Bahauddin Zakariya University, Multan, Pakistan. At the end we concluded that there is no relation between chicken likeness and blood sugar level.


Author(s):  
Mukesh Kumar ◽  
Mukesh Kumar ◽  
Akash Chandra ◽  
Uma Shankar Prasad Keshri ◽  
Rajiv Kumar

Background: Diabetes mellitus is a metabolic disorder in which there is increased blood sugar level, glycosuria, dyslipidemia and sometimes ketonemia occurs. Increased blood sugar level leads to characteristic symptoms such as polydipsia, polyurea, blurring of vision, polyphagia and weight loss.Methods: Healthy male Wister rats weighing between 150-250 gm were taken. Total 2 groups A and B were prepared and each group contains 6 animals. Group A was administered voglibose as 0.6 mg/70 kg body weight. Group B was administered vildagliptin as 100 mg/70 kg body weight. Diabetes was induced in group A and B by administration of 120 mg/kg body weight of nicotinamide and 60 mg/kg body weight of streptozocin intraperitoneally. Streptozocin was administered after 15-20 minutes of administration of nicotinamide. After 72 hours of streptozotocin injection, fasting blood glucose level was determined and induction of diabetes was confirmed. The fasting blood samples were collected from all the groups on further days 7, 14, 21 and 28 day to determine the glucose level by glucometer. Results: The decline in fasting blood sugar level by voglibose was 36.4% on day 7, 40.2% on day 14, 43.94% on day 21 and 46.4% on day 28. The reduction in Fasting blood sugar level by vildagliptin was 49% on day 7, 52.25% on day 14 and 54% on day 21 and 28. Thus in group B rats, decline was maximal on day 7 and little fall was recorded on subsequent days. It suggests good efficacy as vildagliptin normalized the blood glucose level effectively.  Conclusions: Vildagliptin was found significantly more effective in lowering fasting blood glucose level than voglibose.


Author(s):  
Sofyawati D. Talibo ◽  
Imran Tumenggung ◽  
Fatmayanti Nawai ◽  
Rahma Labatjo

Background: Fragrant pandan leaf extract (Pandanus amayllifolius Roxb.) has pharmacological activity as an anti-diabetes, while sweet corn is believed to be a staple food or snack for people with diabetes mellitus. Thus, the foods could be used as an alternative to anti-diabetic functional food. Objective: This study aims to investigate the effectiveness of “Panjang” poffertjes consumption with the addition of pandan leaves extract and sweet corn on the blood glucose level. Methods: This study employs a randomized controlled trial approach with the pre-and post-test design. The data collected on the value of the glycemic index, glycemic load, and the results of 2 hours postprandial (pp) blood sugar level examination after consuming two Poffertjes formulas. The glycemic index (GI) was calculated by employing incremental area under the blood glucose response curve method for ten subjects and a 2-hour postprandial (pp) blood sugar level examination in 25 subjects with the range age between 18-24 years, with normal nutritional status (BMI = 18.58-23.88), 100% had no history of diabetes, did not smoke or alcohol and were not allergic to the tested food ingredients. Results: The results show that the glycemic index of control Poffertjes obtained a value of 71.88 (high category), and “Panjang” Poffertjes got 52.82 (low category). The glycemic load of control Poffertjes obtained a value of 12.78 (medium category), while “Panjang” Poffertjes attained a value of 6.37 (low category). The difference in the average reduction in blood glucose with the intervention poffertjes was 11.08 mg/dl. Conclusion: The provision of “Panjang” poffertjes has a significant effect on the decrease in two-hour postprandial blood glucose level.


2021 ◽  
Vol 53 (3) ◽  
pp. 132-137
Author(s):  
Sri Lestari Ramadhani Nasution ◽  
◽  
Awanis ◽  
Stiven Elsafarindo

Type 2 diabetes is a metabolic disorder caused by insulin resistance and is associated with oxidative stress. In Indonesia, the mean prevalence of diabetes ranges from 1.4% to 1.6%; however, some areas have a much higher diabetes prevalence such as Pekajangan (2.3%) and in Manado (6%). The 2013 Indonesian Basic Health Research (IBHR) stated that the number of people with DM in Indonesia has reached an alarming rate. This study aimed to determine the antidiabetic effect of Polyscias scutellaria on alloxan-induced male Wistar. This was an experimental study conducted in July 2020 in the Faculty of Medicine, Prima Indonesia University. This study used 25 rats that were grouped into 5 treatment groups: control group (Na-CMC), standard (Metformin), and 3 extract groups with different doses (125 mg/kg BW, 250 mg/kg BW, and 500 mg/kg BW). Mangkokan leaf extract was obtained through the maceration method. All ratswere induced intraperitoneally using alloxan monohydrate 10% at a dose of 175 mg/kg BW. The parameters used in this study were fasting blood glucose level before induction, after induction, and after treatment and body weight before treatment. It was observed that there was a significant change in blood glucose level between the extract groups. The blood sugar level in the 125 mg/kg BW group was 495.00 mg/dl while in the 250 mg/kg BW and 500 mg/kg BW, the blood glucose levels were 317.00 mg/dl and 126.00 mg/dl, respectively, with the 500 mg/Kg BW dose as the most effective dose (P-value = 0.001). Thus, mangkokan leaves have the potential to reduce blood glucose level but are not as good as the standard group.


2008 ◽  
Vol 5 (2) ◽  
pp. 123-134 ◽  
Author(s):  
Hirotaka HAYASHI ◽  
Satoshi OHNO ◽  
Takanari ARAI ◽  
Masuo NAKAI ◽  
Yoshio KATO ◽  
...  

1966 ◽  
Vol 52 (3) ◽  
pp. 357-367 ◽  
Author(s):  
Claus Rerup ◽  
Ingmar Lundquist

ABSTRACT Multiple serial blood glucose level determinations in individual mice were performed on small blood samples (10–25 μl) using the orbital bleeding technique. Glucose was determined specifically by a known enzymatic reaction. Blood glucose determined in this way was found a parameter of high reproducibility and precision, the latter being shown by the finding that differences between individual animals were highly significant in practically all the experiments. The standard deviation of the single measurement in normal mice was ± 8.2 mg/100 ml as determined from 600 samples, which indicated that the technique allows of the detection of blood sugar level changes of about 15 mg/100 ml or more with very high significance, in a group of 5 mice. In the sampling procedure as such, intravenous or subcutaneous saline injections did not necessarily have any effect on the blood glucose level, but interpretation of slight blood sugar changes under experimental conditions should always be based on a comparison with control groups, since the latter may sometimes show a slight but significant change. In normal non-fasting mice (NMRI strain) significant differences in homoeostatic blood glucose level adjustments were demonstrated. In acutely adrenalectomized mice blood glucose levels were lower and more variable than in normals. Alloxan injection (70 mg/kg) was followed in individual mice by a triphasic blood sugar response, as is known from other species.


2014 ◽  
Vol 2 (1) ◽  
pp. 48
Author(s):  
Nenni Septyaningrum ◽  
Santi Martini

ABSTRACTThe increasing prevalence of overweight and obesity is associated with the increasing incident of type 2 diabetes mellitus. Obesity, especially abdominal obesity is an important risk factor for the onset of diabetes. The objective of this study was to determine the relationship between body mass index, waist circumference and waist hip ratio with blood glucose level. The study design was cross-sectional. The study population was elderly posyandu member aged 45 to 70 years in Menur clinic work area who were registered in elderly posyandu activities in May 2013. The numbers of sample were 60 respondents who drawn by simple random sampling method. The variabels of this study were the characteristics of respondent, body mass index, waist  circumference,  waist hip ratio and fasting blood glucose level. The study showed that respondents classified as overweight (38%), obesity (33, 3%), abdominal obesity based on waist circumference  (77.8%), abdominal obesity based on waist hip ratio (81,7 %) and blood glucose level more than 125 mg/dl (8.3%). Pearson correlation test showed that there was relationship between body mass index with blood sugar levels (p=0,007; r=0,345), between waist circumference with blood sugar levels (p=0,001; r=0,424) and  between waist hip ratio with blood sugar levels (p =0,002; r=0,392). Waist circumference as the strongest factor related to blood glucose level. Waist circumference measurement should be done in elderly posyandu activities to detect high-risk individuals with diabetes. Keywords: Diabetes, body mass index, waist circumference, waist hip ratio,                     blood glucose level


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