scholarly journals Idiopathic Intracranial Hypertension Associated with Uncontrolled Use of WeightLoss Drugs

2018 ◽  
Vol 2 (2) ◽  

Purpose: We report a case of a patient with bilateral papilledema and Benign Intracranial Hypertension caused by uncontrolled use of drugs for self-treatment of obesity. Methods: A 36-year-old, mildly obese female with a 7-month history of visual changes with floaters, intermittent episodes of diplopia and blurred vision, intense, debilitating, daily headaches, pulsatile tinnitus, bilateral maxillary pressure and pain. Fundus examination revealed papilledema, visual field test detects blind spot enlargement, generalized constriction, and loss of the nasal visual fields, optical coherence tomography (OCT) - increased RNFL thickness in all four quadrants, Lumbar puncture- Increased Intracranial Pressure. Results: The diagnosis of IIH we made according modified Dandy criteria. Conclusion: To our knowledge, this is the first report in literature of BIH caused after self-medication of overweight. Patient during a year lose 40 kg, and she manage it by uncontrolled use of drugs for weight loss.

2021 ◽  
Vol 14 (5) ◽  
pp. e242455
Author(s):  
James Trayer ◽  
Declan O'Rourke ◽  
Lorraine Cassidy ◽  
Basil Elnazir

A 13-year-old male asthmatic presented to the general paediatric clinic with papilloedema identified following a check-up with his optician due to blurred vision. His asthma was well controlled on a moderate dose of inhaled corticosteroid and there had been no recent increase or decrease in the dose. A diagnosis of benign intracranial hypertension (BIH) was made based on a raised cerebrospinal fluid opening pressure, papilloedema, a normal neurological examination and normal neuroimaging. The only associated risk factor was his inhaled corticosteroids. He was commenced on acetazolamide and the inhaled corticosteroid dose was reduced, resulting in resolution of his papilloedema. This case serves to highlight that steroid side effects including BIH may occur at moderate doses of inhaled corticosteroids and that inhaled corticosteroid dose should be regularly reviewed and decreased to the lowest dose that maintains asthma control.


2013 ◽  
Vol 32 (03) ◽  
pp. 204-206
Author(s):  
Carlos Umberto Pereira ◽  
Stephanie Chagas Feitosa ◽  
Alyne Andrade Lima

AbstractMild head injury has been described as rare cause of idiopathic intracranial hypertension (IIH). In the presence of IIH, initial treatment is clinical and surgical treatment, such as lumboperitoneal shunt. Most cases have a good prognosis. The patient have 9-year-old male, went to the emergency room with a history of accidental fall, presenting headache, vomiting and blurred vision. Physical examination showed good overall condition. Neurological examination: normal. Fundoscopy: incipient bilateral papilledema. Normal cranial CT. The general picture suggested by exclusion of other causes IIH diagnosis. He underwent symptomatic treatment with acetazolamide, painkillers and rest. Discharged from the hospital on the eighth hospital day with no complaints being referred for outpatient treatment.


2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Jan O. Aasly

A 40 year old man was admitted with a 2 weeks history of headache, blurred vision and bilateral optic neuritis. During the 6 months period prior to admission he had treated with infliximab infusions for prsoriasis arthritis. He had 0.2 vision in right eye and 0.5 in left Fundoscopy showed moderate disc swelling more on the right than on the left side and right-sided splinter heamorrhages at the disc margin. The intracranial pressure was normal. He was treated with oral methylprednisolone, 100 mg daily for 1 week. His vision improved gradually and when seen 10 weeks later his visual acuity was 1.0 in both eyes and he had normal visual fields. Optic neuritis is a rare but well recognized serious adverse effect of treatments with tumor necrosis factor (TNF) antagonists. This case report illustrates a rare but typical side effect of a TNF alpha inhibitors used for treating a number of inflammatory diseases. These reactions usually appear during first year of treatments and never after the first one or two infusions. Both genders and all ages are affected. In some patients the visual defects are irreversible.


2021 ◽  
Vol 20 (3) ◽  
pp. 114-118
Author(s):  
Jiyoung Lee ◽  
Yeon Woong Chung

Purpose: To report a case of a 29-year-old binocular-diplopia patient diagnosed with intracranial hypertension, caused by a subdural hematoma due to intracranial hypotension.Case summary: A 29-year-old male hypertensive patient, diagnosed 2 months previously with idiopathic intracranial hypotension, presented to an ophthalmologist with a 4-day history of binocular diplopia. Visual acuity was 1.0/0.63 (1.0) without relative afferent pupillary defects. There was bilateral papilledema, right 6th cranial nerve palsy, and blind spot enlargement in visual field examinations, suggestive of intracranial hypertension. Computer tomography of the brain identified a 2- to 3-week-old subdural hematoma, a complication of intracranial hypotension, which may have led to intracranial hypertension.Conclusion: While persistent headaches in intracranial hypertension patients progress to intracranial hypotension due to lowered cerebrospinal fluid pressures, this is the first report of intracranial hypotension progressing to intracranial hypertension.


2015 ◽  
Vol 86 (11) ◽  
pp. e4.43-e4
Author(s):  
Jason Philip Appleton ◽  
Tom Hayton ◽  
Adrian Williams

Idiopathic intracranial hypertension (IIH) is a condition of raised CSF pressure without any apparent structural lesion or problem with venous drainage. We present a lady who was initially diagnosed with IIH, but was later found to have an unusual brain tumour.A 30 year old lady presented in 2012 with a three month history of headaches, nausea and vomiting, two weeks of blurred vision and one week of double vision on looking left. Visual acuity was 6/6 on the right and 6/9 on the left with a left relative afferent pupillary defect, bilateral papilloedema and left lateral rectus palsy. MRI showed ventriculomegaly. Lumbar puncture revealed normal constituents with an opening pressure of 60 cm H2O. In the absence of a space occupying lesion or venous occlusion a diagnosis of IIH was made. A ventriculoperitoneal shunt was inserted and she was discharged but didn't attend follow-up. She re-presented in May 2014 with headaches and intermittent left arm and leg numbness. An MRI revealed widespread CSF pathway infiltration, leptomeningeal enhancement, tonsillar descent and an extensive cervical syrinx. She underwent posterior fossa decompression and biopsy, which was histologically confirmed as pilocytic astrocytoma.Ventriculomegaly is not a feature of IIH. This case illustrates the wide differential of raised CSF pressure and that careful assessment of brain imaging and CSF constituents is required prior to making what is, in effect, a diagnosis of exclusion.


2021 ◽  
Vol 13 (1) ◽  
pp. 233-238
Author(s):  
Seyed Mohammad Mousavi Mirzaei ◽  
Zahra Ahmadi

Drug-induced aseptic meningitis (DIAM) is a rare complication of certain drugs, most commonly reported with ibuprofen use. The present study reports on a male adolescent with intracranial hypertension and visual impairment accompanied by DIAM. We present a 16-year-old male patient who after ibuprofen consumption displayed headache, fever, photophobia, and blurred vision following heavy exercises. Examination of cerebrospinal fluid showed a mononuclear pleocytosis and an increase in protein concentration. Other examinations had normal results. The development of common clinical signs following ibuprofen use reflected DIAM. The patient’s vision was found to improve with supportive care and stopping of the drug during follow-up. Given the widespread use of nonsteroidal anti-inflammatory drugs and the fact that these drugs are the most common cause of DIAM, the probability of occurrence of this event should be always kept in mind, and screening for autoimmune diseases in these patients is of great importance.


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