scholarly journals Investigation of the Effect of Comorbidity on Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 12 (4) ◽  
pp. 5579-5590

Comorbidity is the coexistence of two or more diseases in a certain period. Severe COVID-19 can occur in healthy individuals of any age but predominantly in adults of advanced age or with underlying medical comorbidity. Comorbidities are identified as the main determinants of poor outcomes. This meta-analysis aims to examine the effect of comorbidity on mortality in patients with a diagnosis of COVID-19. Materials and Methods: The studies published between 2019-2020 from Google Scholar, Pub Med, Medline, Scopus, Science Direct, and Web of Science databases were scanned. Inter-rater agreement was calculated with Kappa statistics, effect size "Odds Ratio", heterogeneity between studies with Cochran's Q statistics. The study's effect size and publication bias included in the meta-analysis were calculated using the CMA 3 (Comprehensive Meta-Analysis) program. Results: A total of 24 studies were included in the study. According to the random-effects model, the overall effect size of comorbid factors on mortality development in patients diagnosed with COVID-19 was found to be statistically significant with a value of 2.537 (G.A; 2.078-2.098; p <0.05). In conclusion, cancers, chronic respiratory diseases, diabetes, hypertension, and especially cardiovascular comorbidities are important risk factors for COVID-19 related mortality for COVID-19. There are controversial results in the literature; Further studies involving larger patient groups and examining the specific impact of certain comorbid conditions are needed in order to reach more precise conclusions.

2021 ◽  
Vol 7 (SpecialIssue) ◽  
pp. 231-237
Author(s):  
Naurah Nazifah ◽  
Nurul Azmi ◽  
Putri Nurhaliza ◽  
Desnita Desnita

The industrial revolution 4.0 requires humans to have 21st century skills. In essence, education is expected to produce students who have the quality to live as individuals who are creative, innovative, intelligent, and globally competent. The purposes of this study are to: 1) Determine the effect of Edmodo media on student learning outcomes in the aspect of high school level class levels. 2) Determine the effect of Edmodo media on student learning outcomes on the material used. 3) Determine the effect of Edmodo media on student learning outcomes. The type of research used is meta-analysis. The articles analyzed in this study amounted to 15 articles published in 2014-2021. The average overall effect size of using Edmodo-assisted learning media on high school students' learning outcomes is 2.51 in the high category. The Edmodo-assisted physics learning media provides an effect size on the XI SMA level with an average of 2.91 in the high category, the Edmodo-assisted physics learning media provides an effect size on the XI SMA level with an average of 2.15 in the high category. The highest average value of the effect size of Edmodo-assisted learning media on global warming material with a value of 7.50 in the high category, while the lowest average value of the effect size of Edmodo-assisted learning media on optical instrument materials with a value of 0.87


FONDATIA ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 85-94
Author(s):  
Maulida Anggraina Saputri ◽  
Theresia Sri Rahayu

This study aims to determine the effect of level differences in Problem Based Learning and Discovery Learning model on student’s critical thinking by meta-analysis studies in Mathematics learning, by collecting several relevant journals through Google Scholar. This study uses the Ancove Test to determine the average difference Test in learning model, which has met the Prerequisite Test, then the Effect size is calculated. The result is normal, homogeneous and linear data were obtained with a significance value>0,05. In Ancova Test, the result Discovery Learning is more effective than Problem Based Learning. This is obtained from the results of the posttest scores of 78.4450 for the Problem Based Learning and 83.5840 for the Discovery Learning models. At the Fcount obtained is 7,181, and the Ftable obtained is 3,59, it can be stated that Fcount > Ftable, namely with a value of 7,181 > 3,59 and significance of 0,016 < 0,05. From these results prove that there is a significant difference between the Problem Based Learning and Discovery Learning models on student’s critical thinking in Mathematics learning. In determining the Effect size, it produces a value of 0,0302, it can be stated a moderate influence on student’s critical thinking in Mathematics learning.


2021 ◽  
Vol 79 (4) ◽  
pp. 544-553
Author(s):  
Mehmet Ali Yarim

Professional burnout is one of the most important problems of working life today. In this research it is aimed to follow the relation between job satisfaction and professional burnout of education workers by using meta-analysis method. In this context, examining the relation between occupational burnout and job satisfaction in educational organizations in Turkey master's theses, articles in Google Scholar by National Thesis Center with his doctoral thesis, EBSCO, ULAKBİM and Dergipark databases scanned, and the number of samples required for the meta-analysis and Pearson's correlation coefficient A meta-analysis of 41 (N = 11050) studies containing (r) value was conducted. Effect size values, publication bias, heterogeneity and significance tests results were obtained using the CMA program in the study. In the research study conducted in the random effects model, it was concluded that the p value was less than .05, it took a value between -0.496 - 0.385 lower and upper limits in the 95% confidence interval, and the effect size was at the level of -0.443. Keywords: aimlessness, job satisfaction, burnout, professional burnout, meta-analysis


2018 ◽  
Vol 49 (5) ◽  
pp. 303-309 ◽  
Author(s):  
Jedidiah Siev ◽  
Shelby E. Zuckerman ◽  
Joseph J. Siev

Abstract. In a widely publicized set of studies, participants who were primed to consider unethical events preferred cleansing products more than did those primed with ethical events ( Zhong & Liljenquist, 2006 ). This tendency to respond to moral threat with physical cleansing is known as the Macbeth Effect. Several subsequent efforts, however, did not replicate this relationship. The present manuscript reports the results of a meta-analysis of 15 studies testing this relationship. The weighted mean effect size was small across all studies (g = 0.17, 95% CI [0.04, 0.31]), and nonsignificant across studies conducted in independent laboratories (g = 0.07, 95% CI [−0.04, 0.19]). We conclude that there is little evidence for an overall Macbeth Effect; however, there may be a Macbeth Effect under certain conditions.


2020 ◽  
Vol 03 (04) ◽  
Author(s):  
Shon Shmushkevich ◽  
Massimo Baudo ◽  
Nagla Abdel Karim ◽  
Mahmoud Morsi ◽  
Mariam Khobsa ◽  
...  

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