Magnetic Resonance Imaging (MRI) Evaluation of Sellar Region Tumors with Histopathological Correlation

MRI is a complex, rapidly evolving modality which has assumed an increasingly important role in the diagnosis of Sellar region tumors. It is now the preferred modality for the definitive evaluation and follow-up of the most sellar region tumors. Using different pulse sequence small lesion can be detected even without contrast. Gd-DTPA provides valuable information in MR imaging sellar region tumors, particularly in pre-operative evaluation. This study was conducted to elucidate the accuracy of MRI in pre-operative evaluation of sellar region tumors and its validity by determining sensitivity, specificity, positive and negative predictive value with histopathological correlation. This cross sectional observational study was carried out in the department of radiology and imaging in collaboration with department of Neurosurgery, Dhaka Medical college Hospital, Dhaka during the period of January 2008 to April 2009. MRI of brain was done on 42 patients referred for evaluation of sellar region tumors. The following result and observation were obtained. The age range of the patient was 20 to 80 years. The mean age (HSE) was 34.31(+2.80). Maximum patients were in age group 20-30 years and male-female ratio was 1.8:1. Most sellar region tumor located in the intrasellar with suprasellar extension. Out of 42 patients 37 (88%) patients were truly diagnosed by MRI as sellar region tumors. The sensitivity of MRI to diagnosed macro adenoma was 81.25%, specificity 80.76%, positive predictive value 72.2%, negative predictive value 87.5%, accuracy 80.95%. This study finds that MRI is a valid imaging modality in the diagnosis of pituitary adenoma and sellar region tumor. Bangladesh Med J. 2020 Sept; 49(3) : 1-10

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Pattern of computerized tomography findings of the brain in cerebrovascular accidents

Nepal Journal of Medical Sciences ◽

10.3126/njms.v5i1.36955 ◽

2020 ◽

Vol 5 (1) ◽

pp. 62-70

Author(s):

Elina Shrestha ◽

Narayan Bikram Thapa ◽

SBS Rajbhandari

Keyword(s):

Positive Predictive Value ◽

Negative Predictive Value ◽

Computerized Tomography ◽

Predictive Value ◽

Cerebrovascular Accident ◽

Imaging Modality ◽

P Value ◽

Computerised Tomography ◽

Female Ratio ◽

Sensitivity Specificity

Introduction: Semi-industrialized countries like Nepal have high mortality and disability rates due to cerebrovascular accident, representing for more than 80% of all stroke deaths globally. Stroke is the most common neurological disorder requiring prolonged hospital stay. Aims of our study was to evaluate the role of computerized tomography in evaluation of cerebrovascular accident by differentiating ischemia from hemorrhage and proper identification of negative cases. Methods: A descriptive cross sectional study of total 155 patients, clinically diagnosed as stroke, referred to our department of radiology for computerised tomography evaluation during six month period, were enrolled into study. The clinical information, proper history, computerised tomography findings were properly documented and analysed in SPSS version 20 software. Results: Out of total 155 patients, 85 cases (55 %) were males and 70 cases (45 %) were females with male: female ratio of 1.2:1. The mean age of the patients was 63±15 years. There was significant correlation between clinical with neuroradiological findings as evidenced by p value of 0.000. Sensitivity, specificity, positive predictive value, negative predictive value of clinical findings when correlated to CT in diagnosing ischemic infarction were 84.3%, 67.3%, 82.6%, 70%. Similarly, sensitivity, specificity, positive predictive value, negative predictive value in diagnosing hemorrhagic infarction were 67.3%, 84.3%, 70%, 82.6% respectively. Conclusions: Computerised tomography is the first line reliable imaging modality for diagnosis, management of cerebrovascular accident and exclusion of stroke mimicker lesions. Education regarding prevention and control of modifiable risk factors can minimize the incidence of stroke.

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Comparison of RMI 3 and RMI 4 in pre-operative evaluation of ovarian masses

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193782 ◽

2019 ◽

Vol 8 (9) ◽

pp. 3602

Author(s):

Badugu Rao Bahadur ◽

Gangadhara Rao Koneru ◽

Prabha Devi Kodey ◽

Jyothi Melam

Keyword(s):

Positive Predictive Value ◽

Negative Predictive Value ◽

Predictive Value ◽

Malignant Tumors ◽

Clinical Approach ◽

Ovarian Mass ◽

Medical College ◽

Operative Evaluation ◽

Sensitivity Specificity ◽

Final Confirmation

Background: To differentiate ovarian mass as benign or malignant could change clinical approach. Finding a screening and diagnostic method for ovarian cancer is challenging due to high mortality and insidious symptoms. Risk malignancy index (RMI) has the advantage of rapid and exact triage of patients with ovarian mass.Methods: Prospective study carried for 2 years at NRI Medical College and General Hospital, Chinakakani, Mangalagiri, Andhra Pradesh, India. 79 patients with ovarian mass were investigated and risk malignancy index (RMI-3 and RMI-4) calculated. Final confirmation was done based on histopathological report. Sensitivity, specificity, positive predictive value and negative predictive value were calculated for RMI 3 and RMI 4 taking histopathology as control and comparison was done.Results: (n=79); 50 (63.29%) cases were benign and 29 (36.70%) were malignant based on histopathology. RMI 4 is more sensitive (68.96%) than RMI 3 (62.06%), but RMI 3 is more specific (94%) than RMI 4 (92%).The positive predictive value of RMI-3 and RMI-4 were 85.71% and 83.33% respectively. The negative predictive value for RMI-4 and RMI-3 were 83.63% and 81.03% respectively.Conclusions: With increasing age, chance of malignancy increases. RMI 4 was more sensitive than RMI-3, however less specific than RMI 3 in differentiating benign and malignant tumors. The positive predictive value is slightly more for RMI 3, than RMI 4. Negative predictive value is slightly more for RMI 4, than RMI 3.

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Diagnostic Value of Ultrasonography in Patients Suspected Acute Appendicitis

Nepalese Journal of Radiology ◽

10.3126/njr.v2i2.7680 ◽

2013 ◽

Vol 2 (2) ◽

pp. 13-19

Author(s):

MA Elahifar ◽

H Taheri ◽

A Bighamian

Keyword(s):

Acute Appendicitis ◽

Negative Predictive Value ◽

Predictive Value ◽

Histopathological Examination ◽

Imaging Modality ◽

Diagnostic Value ◽

Preoperative Imaging ◽

Outpatient Basis ◽

Abdominal Ultrasonography ◽

Cell Counts

Introduction: Appendectomy is one of the most frequently performed abdominal operations in surgical practice. Preoperative imaging has been demonstrated to improve diagnostic accuracy in appendicitis. Abdominal ultrasonography (US) is the most commonly and first-line imaging modality used for diagnosing acute appendicitis (AA).The aim of this study was to demonstrate the diagnostic value of abdominal ultrasonography for diagnosing acute appendicitis. Methods: In a retrospective study, we analyzed 200 consecutive patients with abdominal pain that undergoing appendectomy, from June 2009 to April 2012. Patient characteristics, preoperative ultrasonography (US) and laboratory assessment including WBC were collected. Final diagnosis of appendicitis was confirmed by histopathological examination. Results were compared with US. Results: Two hundred patients were admitted to this study that undergoing appendectomy. Mean age was 24 years (range: 1 to 91 years), and 57% were females. Patient White blood cell counts were found to be high in 78% while it was 86% for AA group and 64% for NA group (p < 0.05). One hundred sixty-six of these patients (83%) were diagnosed as acute appendicitis on pathology, and 34 (17%) were diagnosed differently. 157 of patients underwent US, eighty two of this patients diagnosed as acute appendicitis on US examinations and in 78 of them were also reported as acute appendicitis on histopathological examination. The sensitivity and specificity of abdominal US for diagnosing appendicitis were 70% and 90.2% respectively. Positive predictive value (PPV) was 93% and negative predictive value (NPV) was reported 62%. Conclusion: Ultrasonography has a high PPV and specificity, so as a diagnostic tool, positive US strongly suggests the diagnosis of AA. A low negative predictive value recommends that negative US is not sufficient to exclude the diagnosis of AA and patients could not be managed on an outpatient basis following a negative scan. Nepalese Journal of Radiology; Vol. 2; Issue 2; July-Dec. 2012; 13-19 DOI: http://dx.doi.org/10.3126/njr.v2i2.7680

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A Comprehensive Approach to Thyroid Swellings: Clinical, Sonological, Cytological and Histopathological Correlation

Otorhinolaryngology Clinics - An International Journal ◽

10.5005/jp-journals-10003-1143 ◽

2014 ◽

Vol 6 (1) ◽

pp. 5-8

Author(s):

MC Trupthi ◽

S Boobalan

Keyword(s):

Diagnostic Accuracy ◽

Predictive Value ◽

Surgical Intervention ◽

Comprehensive Approach ◽

Referral Centre ◽

Tertiary Referral ◽

Tertiary Referral Centre ◽

Female Ratio ◽

Histopathological Correlation ◽

Male To Female

ABSTRACT Objectives This study was conducted with the aim of clinicopathological evaluation of thyroid swellings. Setting Tertiary referral centre, Davangere, Karnataka, India. Design Retrospective study. Materials and methods Clinical details, sonological reports, laboratory reports were retrieved from the records for the 110 patients with thyroid swellings who were included in our study, between May 2009 and April 2013 and the data was analyzed. Cytological smears in all patients and histopathology slides in operated patients were retrieved and studied. Results The highest incidence (37.4%) of thyroid swellings were found in age group of 21 to 30 years. The youngest patient being 10 years. Females (90%) predominated in this study, male to female ratio being 1:9. Majority of patients (35%) came with complaints of swelling of duration less than 6 months. Among 110 patients, 36.36% of them were treated conservatively, out of which 7 cases (17.5%) were hyperthyroid, 10 cases (25%) were hypothyroid and 23 cases (57.5%) were euthyroid and the remaining 63.63% of them underwent surgery. Of the 110 patients subjected to FNAC, 16 patients (14.54%) were neoplastic and 94 patients (85.45%) were non-neoplastic. Upon correlation with the histopathology report, the sensitivity of FNAC was 78.57%, specificity was 91.07%, with a positive predictive value of 68.75% and negative predictive value of 94.44%. Diagnostic accuracy of FNAC is 88.50%. Conclusion FNAC and USG are valuable tools in assessing the need for surgical intervention in thyroid swellings. USG guided aspiration will further enhance the cytological yield and diagnostic accuracy. How to cite this article Santosh UP, Sunil Kumar KB, Trupthi MC, Boobalan S. A Comprehensive Approach to Thyroid Swellings: Clinical, Sonological, Cytological and Histopathological Correlation. Int J Otorhinolaryngol Clin 2014;6(1):5-8.

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OP0180 DIAGNOSTIC VALIDITY OF ULTRASOUND INCLUDING EXTRA-CRANIAL ARTERIES IN GIANT CELL ARTERITIS

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.5036 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 112.2-112

Author(s):

I. Monjo ◽

E. Fernández ◽

D. Peiteado ◽

A. Balsa ◽

E. De Miguel

Keyword(s):

Positive Predictive Value ◽

Giant Cell Arteritis ◽

Giant Cell ◽

Negative Predictive Value ◽

Predictive Value ◽

Ultrasound Examination ◽

Axillary Artery ◽

Imaging Modality ◽

Large Vessel ◽

Research Support

Background:Giant cell arteritis (GCA) is a chronic vasculitis of the medium and large arteries. The involvement of large vessel (LV) either isolated or associated with cranial artery is frequent, so it is necessary to use imaging techniques for diagnosis, because the biopsy in these cases is not useful. European League Against Rheumatism (EULAR) recommends an early imaging test in patients with suspected GCA, and ultrasound of temporal±axillary arteries is recommended as the first imaging modality in patients with suspected predominantly cranial GCA (1).Objectives:To assess the validity of Colour Doppler ultrasound (CDUS) of temporal superficial arteries (TA) and LV (axillary, subclavian and carotid) in the diagnosis of GCA, using as gold standard the patient’s definitive clinical diagnosis. Analyse if routine ultrasound examination of LV improves the diagnostic accuracy.Methods:This was an observational, descriptive and analytical study of 198 consecutive patients with GCA suspicion. A baseline CDUS of the TA and LV was performed. Ultrasound diagnosis was made according to the OMERACT (Outcome Measures in Rheumatology) definitions of halo sign and was established as a limit of average intimal thickness ≥ 0.34 mm for superficial temporal arteries and ≥ 1 mm for axillary, subclavian and carotid arteries. Statistical analysis was performed using SPSS version 25.Results:Eighty-seven patients (43.9%) were CDUS compatible with GCA, and 111 patients (56.1%) had a negative CDUS. Among the patients with positive CDUS three different patterns were detected: 45 patients (51.7%) had an exclusive cranial involvement, 31 (35.6%) had a mixed pattern with involvement of both TA and LV and 11 (12.6%) had an exclusive LV involvement. The validity (sensitivity and specificity) and security (positive predictive value and negative predictive value) of diagnostic are shown in table.When we analyse patients with LV involvement, 87.8% have axillary artery involvement, 77.4% subclavian involvement and 34.4% carotids involvement. If we only explored the axillary arteries, 12.2% of patients with LV involvement would not be diagnosed. However, if we explored axillary and subclavian arteries, 100% of patients with LV involvement would be diagnosed.Conclusion:Half of the patients with GCA have LV involvement and up to 12.8% exclusively LV affectation in our series. Adding CDUS exploration of LV arteries to TA increases both sensitivity and diagnostic specificity. The minimum ultrasound examination of LV should include both axillary and subclavian arteries.References:[1]Dejaco C, Ramiro S, Duftner C, et al. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice. Ann Rheum Dis. 2018;77(5):636–3SensitivitySpecificityPositive predictive valueNegative predictive valueCDUS TA and LV97,7%97,3%96,6%98,2%CDUS TA83,9%97,3%96,1%88,5%Disclosure of Interests:Irene Monjo: None declared, Elisa Fernández: None declared, Diana Peiteado: None declared, Alejandro Balsa Grant/research support from: BMS, Roche, Consultant of: AbbVie, Gilead, Lilly, Pfizer, UCB, Sanofi, Sandoz, Speakers bureau: AbbVie, Lilly, Sanofi, Novartis, Pfizer, UCB, Roche, Nordic, Sandoz, Eugenio de Miguel Grant/research support from: Yes (Abbvie, Novartis, Pfizer), Consultant of: Yes (Abbvie, Novartis, Pfizer), Paid instructor for: yes (AbbVie, Novartis, Pfizer, MSD, BMS, UCB, Roche, Grunental, Janssen, Sanofi), Speakers bureau: yes (AbbVie, Novartis, Pfizer, MSD, BMS, UCB, Roche, Grunental, Janssen, Sanofi)

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Accuracy of Reflexive Behavioral (“Baah”) Test in the Screening for Hearing Impairment in Infants Six Months Old and Below

Philippine Journal of Otolaryngology Head and Neck Surgery ◽

10.32412/pjohns.v27i1.543 ◽

2012 ◽

Vol 27 (1) ◽

pp. 6-11 ◽

Cited By ~ 1

Author(s):

Marieflor Cristy M. Garcia ◽

Charlotte M. Chiong ◽

Generoso T. Abes ◽

Ryner Jose C. Carrillo

Keyword(s):

Hearing Loss ◽

Negative Predictive Value ◽

Hearing Impairment ◽

Predictive Value ◽

Hearing Screening ◽

Newborn Hearing Screening ◽

Care Providers ◽

Government Hospital ◽

Female Ratio ◽

Newborn Hearing

Objective: To determine the prevalence of hearing loss among infants six months old and below sent for newborn hearing screening in our institution, and to measure the accuracy, sensitivity, specificity and positive predictive values of reflexive behavioral (“Baah”) test in detecting hearing loss in infants.Methods: Design: Cross-sectional study Setting: Ear Unit of a tertiary government hospital Participants: Infants less than Six months old sent for newborn hearing screening at the Ear Unit of a tertiary government hospital from April to September, 2011 were recruited. All participants were tested with OAE for hearing screening. OAE was also used as the standard for evaluating hearing impairment. The reflexive behavioral (“Baah”) test was then done using the human voice as a loud sound stimulus, and the response recorded were auropalpebral, startle and blinking response to the sound. Thesensitivity, specificity, accuracy, positive and negative predictive value of the test was then measured.Results: From April to September 2011, a total of 101 patients were tested, with a male to female ratio of 1.1:1 (53 males, 48 females). The prevalence of hearing impairment in this study population was 6.9% (7 out of 101). The reflexive behavioral (“Baah”) test was found to have sensitivity of 71.4%, specificity of 95.7%, accuracy rate of 94%, positive predictive value of 55.6% and negative predictive value of 97.8%.Conclusion: The reflexive behavioral (“Baah”) test shows potential as an accurate, acceptable and cost-effective screening tool to identify infants that may be at higher risk for hearing impairment. This test may aid the health care providers, in areas without OAEs, in identifying infants who are in need further hearing diagnostic evaluation, with OAEs or other hearing tests. It is recommended that the “Baah” test be implemented in the community to test its reproducibility in a larger population and outside the hospital setting.Keywords: reflexive behavioral test, “Baah” test, otoacoustic emission, hearing screening

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Prediction of difficult airway by thyromental height test- a comparison with modified mallampati test.

Bangladesh Journal of Medical Science ◽

10.3329/bjms.v17i3.37014 ◽

2018 ◽

Vol 17 (3) ◽

pp. 455-461

Author(s):

Md Nurullah ◽

Md Shah Alam ◽

Mahmud Hossen ◽

Marufa Shahnawaz

Keyword(s):

Difficult Airway ◽

Negative Predictive Value ◽

Likelihood Ratio ◽

Predictive Value ◽

Medical Science ◽

Positive Likelihood Ratio ◽

Negative Likelihood Ratio ◽

Predictive Values ◽

Female Ratio ◽

Patent Airway

Background: Management of airway is central to the Practice of anaesthesia. One of the anaesthesiologist fundamental roles is to maintain a patent airway at a all times.Maintaining a patent airway is essential for adequate oxygenation and ventilation and failure to do so, even for a brief period of time, can be life threatening. Recently, thyromental height test (TMHT) has been proposed as one of the highly sensitive and specific bedside tests to predict difficult airway.Objective: To assess the predictivity of thyromental height test in comparison to modified Mallampati test.Methods: This cross sectional study was carried out in Anesthesiology department of ISMCH during the period of January, 2015 to December, 2016. A total number of 139 consecutive patients scheduled for elective surgical procedure under general anaesthesia requiring intubation having American Society of Anesthesiologists grading I-II. Statistical analyses of the results were obtained by SPSS-20. Sensitivity, specificity, accuracy, positive predictive value and negative predictive value of Thyromental height test and Modified mallampati scoring in diagnosis of difficult airway were calculated.Results: Most (74.4) of the patients belonged to age ≤50 years. Male to female ratio was 1.01:1. Majority 91(65.5%) patients had thyromental height of ≥50 mm. In the diagnosis of difficult airway, Thyromental height test was 92.7% sensitivity, 93.5% specificity, 93.5% accuracy and 85.4% positive predictive values, 97.8% negative predictive value, 13.1% positive likelihood ratio, 0.05 negative likelihood ratio. On the other hand Modified mallampati scoring was 48.8% sensitivity, 92.7% specificity, 79.1% accuracy, 75.0% positive predictive values, 80.2% negative predictive value, 6.7% positive likelihood ratio, 0.55 negative likelihood ratio for prediction of difficult airway.Conclusions: It can be concluded that the thyromental height is useful diagnostic modality for predicting difficult airway.Bangladesh Journal of Medical Science Vol.17(3) 2018 p.455-461

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1.5-Tesla Multiparametric-Magnetic Resonance Imaging for the detection of clinically significant prostate cancer

Medicine and Pharmacy Reports ◽

10.15386/cjmed-690 ◽

2017 ◽

Vol 90 (1) ◽

pp. 40-48

Author(s):

Cristian Popita ◽

Anca Raluca Popita ◽

Adela Sitar-Taut ◽

Bogdan Petrut ◽

Bogdan Fetica ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Prostate Cancer ◽

Magnetic Resonance ◽

Negative Predictive Value ◽

Predictive Value ◽

Imaging Modality ◽

High Sensitivity ◽

Resonance Imaging ◽

Multiparametric Magnetic Resonance Imaging ◽

Clinically Significant

Background and aims. Multiparametric-magnetic resonance imaging (mp-MRI) is the main imaging modality used for prostate cancer detection. The aim of this study is to evaluate the diagnostic performance of mp-MRI at 1.5-Tesla (1.5-T) for the detection of clinically significant prostate cancer.Methods. In this ethical board approved prospective study, 39 patients with suspected prostate cancer were included. Patients with a history of positive prostate biopsy and patients treated for prostate cancer were excluded. All patients were examined at 1.5-T MRI, before standard transrectal ultrasonography–guided biopsy.Results. The overall sensitivity, specificity, positive predictive value and negative predictive value for mp-MRI were 100%, 73.68%, 80% and 100%, respectively.Conclusion. Our results showed that 1.5 T mp-MRI has a high sensitivity for detection of clinically significant prostate cancer and high negative predictive value in order to rule out significant disease.

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Evaluation of Neck Mass by Multidetector Computed Tomography and Histopathological Comparison.

Bangladesh Medical Research Council Bulletin ◽

10.3329/bmrcb.v43i3.36414 ◽

2018 ◽

Vol 43 (3) ◽

pp. 115-119

Author(s):

Umme Iffat Siddiqua ◽

Bibek Ananda Halder ◽

Rued Hossain ◽

Shyamal Kumar Roy ◽

Abdullah Al-Amin ◽

...

Keyword(s):

Computed Tomography ◽

Multidetector Computed Tomography ◽

Negative Predictive Value ◽

Predictive Value ◽

Multidetector Ct ◽

Imaging Modality ◽

Neck Mass ◽

Histopathological Diagnosis ◽

Ct Scanner ◽

Cross Sectional

Diagnostic usefulness of multidetector computed tomography (MDCT) scan in the evaluation of neck mass was assessed in this study in terms of sensitivity, specificity, positive and negative predictive value and accuracy in respect to characterise the lesion as benign and malignant, based on different parameters by comparing computed tomography and histopathological findings. This cross sectional study was carried out on 57 patients in the Department of Radiology and Imaging, Sir Salimullah Medical College and Mitford Hospital, Dhaka from January 2014 to December 2015, with a 16 slice multidetector CT scanner and the reports were compared to histopathological diagnosis. Out of 57 patients, 37 (64.9%) and 20 (35.1%) were diagnosed as malignant and benign lesions respectively, with a sensitivity of 94.6%, specificity 95%, positive predictive value 97.2%, negative predictive value 90.5% and diagnostic accuracy of 94.7%. As an imaging modality, thus, MDCT proved to be a useful tool for assessing and characterization of neck mass as benign and malignant, especially in this part of the continent, and is essential in planning surgical approach and predicting prognosis.

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Acute Appendicitis - Study of Role of Ultrasound and CT Scan in Decision Making for Surgery in a Tertiary Care Government Hospital in Eastern India

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/556 ◽

2021 ◽

Vol 8 (33) ◽

pp. 3048-3053

Author(s):

Jainendra Kumar ◽

Akriti Komal

Keyword(s):

Computed Tomography ◽

Acute Appendicitis ◽

Positive Predictive Value ◽

Negative Predictive Value ◽

Predictive Value ◽

Imaging Modality ◽

Tertiary Care ◽

Accurate Diagnosis ◽

Final Decision ◽

Sensitivity Specificity

BACKGROUND Acute appendicitis (AA) is one of the commonest causes of acute abdominal emergencies. Accurate diagnosis and earlier surgery is imperative in such cases. Ultrasonography (US), and computed tomography (CT), are main stays accurate diagnosis of this disease. This study was conducted to compare the accuracy of US and CT in the diagnosis of AA and reduce number of negative appendectomies. METHODS This prospective study was done after approval from institutional ethical committee and obtaining written consent. 164 patients with clinical features suggestive of AA, were selected from emergency department of Patna Medical College, Patna India during the period from January 2019 to December 2020. 98 were males and 66 females, mean age being 18.08 years. 142 patents (86.58 %) underwent surgery, and 22 patients (13.41 %) were kept on clinical observation in hospital after imaging. After detailed clinical workup and laboratory investigations, all patients were subjected to both US and CT examination. Each patient was reevaluated clinically, and a clinical correlation was done between both sets of results. Based on these, final decision was made. Accuracy was decided based on intra-operative findings in appendectomy group and were correlated with imaging findings later with histopathologic findings. RESULTS Males outnumbered females, abdominal pain was present in 100%. The sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy of US in diagnosis of AA in our study were 92.6 %, 76.4 %, 95.3%, 71.0% and 88.9 % respectively. The sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy of CT in diagnosis of AA were 99.1 %, 90.5 %, 98.6%, 87.8% and 97.8 % respectively. CONCLUSIONS US should be the first-line imaging modality as it is free from radiation. CT is recommended as additional imaging tool to raise accuracy in diagnosis except in pregnancy and selected pediatric patients. KEYWORDS Acute Appendicitis, Computed Tomography, Ultrasound

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