scholarly journals Aetiology and Clinical Presentation of Pancytopenia in a Teaching Hospital

2019 ◽  
Vol 13 (2) ◽  
pp. 62-65
Author(s):  
ATM Ataur Rahman ◽  
ARM Saifuddin Ekram ◽  
Mohammed Shahadat Hossain ◽  
Jayanta Kumar Saha ◽  
Fahreen Rahman ◽  
...  

Pancytopenia is a morphological description of the peripheral blood picture irrespective of its cause & it denotes simultaneous presence of anaemia, leucopenia and thrombocytopenia. The study was done to observe the demographic profile & the clinical presentations of pancytopenic patients and to find out the aetiology of pancytopenia. This cross sectional study was carried out in Medicine ward of Rajshahi Medical College Hospital from August 2005 to July 2006. A uniform protocol was followed in all cases, to have appropriate history, physical findings & laboratory investigations. The commonest cause of pancytopenia was aplastic anaemia (48%) which was followed by hypersplenism (22%) & acute leukemia (16%). The majority cases of aplastic anaemia were idiopathic (57.69%), only 42.31% cases were due to secondary causes. The majority (94%) of patients was in the age range of 14-60 years and up to 54% was in the age group of 20-40 years. The ratio of male to female in patients of pancytopenia was 1.5:1 and 3:1 in aplastic anaemia. In secondary causes of aplastic anaemia, insecticides and viral hepatitis was found to be causative agent in 45.45% cases of each followed by pregnancy in 9.10% of cases. The common presenting complains of aplastic anaemia were generalized weakness (100%), gum bleeding (76.92%), fever (76.92%) and pallor (96.15%). Faridpur Med. Coll. J. Jul 2018;13(2): 62-65

2020 ◽  
Vol 27 (09) ◽  
pp. 1818-1822
Author(s):  
Zulfiqar Ali Imtiaz Memon ◽  
Mashooque Ali Khowaja ◽  
Inayat Ali Zardari ◽  
Altaf Hussain Ghumro ◽  
Farkhanda Jabeen Dahri ◽  
...  

Objectives: The purpose is to compare two options of management of appendicular lump in order to sort out the better one for the benefit and betterment of populace. Study Design: Cross Sectional study. Setting: Peoples Medical College Hospital Nawabshah. Period: 2016 August to August 2018. Material & Methods: Total 50 patients of appendicular lump were included in this research. All patients were divided into 2 groups. Group 1 included those patients undergoing emergency appendectomy. They were admitted, optimized and the required treatment was initiated. Results: Of total 50, 30(60%) were male and 20(40%) were females. Age was between 14 to 51 years. All patients presented with different clinical presentations. Pain in RIF was in 42(84%) patients whereas 47(94%) patients presented with lump in RIF. 20(40%) patients were operated for appendectomy in emergency and 5(10%) patients for right hemi-colectomy. Histopathological diagnosis was inflammation in 24(48%) patients and 1(2%) resulted in cecal tumor. Infected wound was found in 15 (30%) patients, hematoma in 3 (6%), wound dehiscence in 1(2%) and also cecal fistula in 1 (2%). Conclusion: Conservative treatment is better option to treat appendicular lump with least negative results.


2017 ◽  
Vol 6 (2) ◽  
pp. 6-11
Author(s):  
Netay Kumer Sharma ◽  
Sankar Narayan Dey ◽  
Md Masudur Rahman ◽  
Akter Zahan ◽  
Mahzabeen Islam ◽  
...  

Determination of gestational age by ultrasound has now become an integral part of maternal antenatal care. Accurate assessment of gestational age by sonography is now essential for obstetric management particularly due to term, preterm and post date management. Timing of elective caesarean delivery and decision whether to consider a fetus at risk for intrauterine growth retardation depends in part on the estimated age. In this study gestational age was determined on the basis of head circumference (HC) and correlation was established between weeks of gestation calculated from LMP. A cross sectional study was carried out in the department of Radiology & Imaging, Mymensingh Medical College Hospital during the period of January 2011 to June 2012. Three hundred ninety seven normal pregnant Bangladeshi women age range from 20 to 36 years with apparently healthy fetuses between 18 to 38 weeks of gestation referred for ultrasonic evaluation of pregnancy profile. Mean age was 29.60 years with standard deviation (SD) +0.67. Aim of this study was to determine relationship between menstrual age and HC. Result of this study may give idea about gestational age calculated by LMP of 397 cases and expressed in weeks. Estimated gestational age was determined by HC evaluated by US and expressed in weeks. Significant positive correlation was found between gestational age measured by HC and LMP. Estimated gestational age measured by HC had very close relation with weeks of gestation(LMP), which is 2 to 3 days less from weeks of gestation (LMP) during 18-38 weeks of gestation variation was only 2 to 4 days less from weeks of gestation (LMP). A strong positive significant correlation (r=0.987, P<0.001) was found between weeks of gestation and predicted gestational age measured from HC. Significant relationship between gestational age measured by LMP with estimated gestational age evaluated by head circumference. CBMJ 2017 July: Vol. 06 No. 02 P: 06-11


2019 ◽  
Vol 26 (11) ◽  
pp. 1844-1849
Author(s):  
Muhammad Amin ◽  
Mukhtar Ahmad ◽  
Malik Muhammad Naeem ◽  
Muhammad Amir Ramzan

Objectives: Recent years have seen advances in respiratory supports for meconium aspiration syndrome (MAS) but pneumothorax (PTX) still stands a significant indicator of disease severity. This study was aimed to determine the frequency of PTX in newborn with meconium aspiration. Study Design: Descriptive, cross-sectional study. Setting: Department of Pediatric Medicine, Unit 1, Bahawal Victoria Hospital, Bahawalpur, and Department of Pediatric Medicine, Ghazi Khan Medical College/Hospital, Dera Ghazi Khan. Period: 1st June 2017 to 30th September 2018. Material and Methods: A total of 736 patients with meconium aspiration of age 1-28 days and both genders were included. Patients with congenital heart anomalies and preterm infants were excluded. Presence or absence of PTX in each patient was noted. Results: Age range in this study was from 1 to 28 days with mean age of 12.80 ± 6.52 days. Majority of the patients 434 (58.97%) were between 1 to 14 days of age. Out of the 736 patients, 394 (53.53%) were male and 342 (46.47%) were females with male to female ratio of 1.2:1. Frequency of PTX in newborn with meconium aspiration was found in 176 (23.91%) patients. Conclusion: Frequency of PTX in newborn with meconium aspiration is quite high. In every newborn with meconium aspiration, proper management should be done for early prevention as well as taking therapeutic measures in this particular population.


2021 ◽  
Vol 16 (1) ◽  
pp. 39-41
Author(s):  
Mohammad Iqbal Hossain ◽  
Md Aynul Islam ◽  
MM Bodiuzzaman ◽  
Md Shahidul Islam Talukder ◽  
MM Shahin Ul Islam ◽  
...  

Liver cirrhosis is an important cause of death and disability globally. This cross-sectional study was carried out in Faridpur Medical College Hospital from November 2018 to April 2019 to see the patterns of clinical presentations and associated factors among admitted liver cirrhosis patients. A total of 89 patients were included. Data were collected by detailed history from patients or their relatives followed by thorough physical examination as well as diagnostic evaluation; then those were checked, verified for consistency and edited for result. Among total respondents, the majority were male (69.7%) with a male to female ratio of 1:0.44. Age of patients ranged between 22-106 years with mean age of 52.33 year. The patients predominantly presented with ascites (49.4%), gastrointestinal bleeding (27%), peripheral edema (24.7%), and encephalopathy (21.3%). The in-hospital case fatality rate was 11.2% and the patients presented with decreased urinary output, peripheral edema and encephalopathy had statistically significant death rate. The results of the study highlighted that the patients with liver cirrhosis mostly present with features of decompensation and there is a statistically significant relation with some of these clinical presentations with in-hospital mortality. Faridpur Med. Coll. J. 2021;16(1):39-41


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


2021 ◽  
Vol 9 (2) ◽  
pp. 3-7
Author(s):  
Iffath Farooqui ◽  
Md Shamsul Islam ◽  
Rahat Amin Chowdhury ◽  
ATM Hasibul Hasan

The sexual assaults and its consequences are increasing along with socioeconomic development of the country. Rise of modern communication technology add fuel to the flame. This descriptive cross-sectional study aimed to evaluate the role of communication technology in sexual assaults in Bangladesh. There were 87 victims included in this study. All were female of 6 years to 40 years of age, mean age was 15.67 (± 6.69) year. Most of the victims were below 20 years of age and came from low income families. About 76% mobile used were smart phone. Among them 46% were owned by the victims herself, 26% gifted by the assailants to the victims. Talking through mobile (37%) was the main communication route between the assailants and the victims; followed by direct verbal (31%), mixed verbal and mobile talking (26%) and others (6%). Regarding methods of communication, they only talk in 42% cases and 36% cases used mixed method (talking, SMS and video chatting). The assailant paid all the costs in 62% cases. Mobile phone came as a blessing in communication, but inchoate use makes it a curse to our society. Parents should be cautious about their children's mobile usage (especially smart phone) daily. Government also should make some policy on using mobile technology by the younger citizens. CBMJ 2020 July: Vol. 09 No. 02 P: 03-07


2013 ◽  
Vol 3 (1) ◽  
pp. 29-31
Author(s):  
Swapna Bhattacharjee ◽  
Shekhar Bhattacharjee ◽  
Rukhsana Parvin

Background: Cough variant asthma (CVA) is a subset of asthma where the only symptom is chronic persistent cough. Many cases go unrecognized due to lack of proper evaluation. Response to asthma medication with features supportive of airway hypersensitivity helps in management of this disease. Objective: To find out the proportion of cough variant asthma among the patients attending medicine outpatient department of Enam Medical College, Savar, Dhaka. Materials and Methods: This cross sectional study was conducted in Enam Medical College Hospital, Savar, Dhaka over a period of two years from July 2009 to July 2011. Cough variant asthma was diagnosed mainly on clinical ground as chronic cough without wheezing, fever, weight loss, shortness of breath or sputum or any other apparent cause that persisted for more than eight weeks with absolutely normal physical examination of chest, normal chest radiography and blood count except raised eosinophil count and IgE level. Patients who met these criteria were given 2 weeks course of inhaler beclomethasone propionate and were assessed for improvement. Those who improved after steroid inhalation were categorised as having cough variant asthma. Results: Out of purposively selected 148 patients complaining only of chronic dry cough for more than eight weeks, 92 patients met the primary selection criteria for cough variant asthma. These 92 patients were given 2 weeks trial of 250 ìgm beclomethasone inhalation twice daily. Seventy nine patients reported almost complete recovery from chronic cough after 2 weeks and were categorized as having CVA. Thirteen patients did not improve and were not categorized as CVA. Conclusion: These findings suggest that cough variant asthma is the most common among the patients with chronic cough not due to any apparent cause. The efficacy of inhaled corticosteroid suggests that early intervention is effective in the treatment of this disease. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13871 J Enam Med Col 2013; 3(1): 29-31


2021 ◽  
Vol 15 (6) ◽  
pp. 1243-1245
Author(s):  
H.U Rahman ◽  
S. F. Shah ◽  
A. J. Sheikh ◽  
I. U. Memon ◽  
W. S. Bhatti ◽  
...  

Aim: To assess the metabolic abnormalities in children younger than 10 years of age with vesical calculus. Study design: Retrospective cross-sectional study Place and duration of study: Department of Urology, Khairpur Medical College Hospital, Khairpur from 1st October 2014 to 30th September 2016. Methodology: Two hundred and six children age <10 years of age and either gender presented with vesical calculus were enrolled. Demographic information like age, gender, residence, serum electrolytes, calcium, magnesium, phosphate, uric acid, blood, and urine pH were recorded for the purpose of metabolic workup. Results: The mean age was 4.76±1.22 years and 157 (76.2%) were males and 49 (23.8%) were females. The frequency of metabolic abnormalities was observed in 153 (74.3%) of the patients. A significantly higher prevalence of metabolic abnormalities was observed with male gender (p-value 0.006), dark colored urine as presenting symptoms (p-value 0.022), frequent urination (p-value 0.045), and hematuria (p-value 0.016). Of 153 patients with metabolic abnormalities, hypercalciuria was observed in 45 (29.4%), hypocitraturia in 73 (47.7%), hyperoxaluria in 21 (13.7%), and hyperuricosuria in 14 (9.2%) patients. Conclusion: The frequency of metabolic abnormalities was high among children with vesical calculus. Moreover, hypocitraturia in these children was observed in majority followed by hypercalciuria, hyperoxaluria, and hyperuricosuria. Keywords: Metabolic abnormalities, Children, Vesical calculus


2021 ◽  
pp. 112-113
Author(s):  
Meghashree N ◽  
Rohini D ◽  
Mahendar Reddy M ◽  
A.M Koppad

Introduction: Eosinophilia is a well-known host immune response in helminthic infestation. This study was carried out to investigate whether a correlation exists between absolute eosinophil count in children with stool specimen positive for helminthic infestation. Aim And Objective: To determine average raised absolute eosinophil count in children who were having various helminthic infestation with stool specimen positive. Materials And Methods: A hospital based cross sectional study done at Navodaya medical college hospital and research centre during 2019 October to 2020 September for a period of 12 months. Both blood and stool samples were obtained from a total of 69 suspected children after examined, categorised into 2 groups. Among them 24 cases were positive of helminthic infestation and 45 cases were negative. T-test and descriptive statistics were used to analyse the data. Results: The study revealed that children infested with helminths found to have higher absolute eosinophil count (mean 4644/µl (95%CI; 3474-4212) than not infested (mean 801/µl (95%CI; 616-945) with p value <0.001. In this helminth's family; nematodes, trematodes, cestodes showed mean values of absolute eosinophil count were 5206/µl (4806-7151/µl), 4930/µl (4500-5382/µl) and 2179/µl (2500-1669/µl) respectively. Conclusions: Raised absolute eosinophil count has been observed in stool specimen positive cases of helminths, especially more in nematodes. Therefore, should be considered for a single dose of albendazole.


2020 ◽  
Vol 7 (1) ◽  
pp. 12-17
Author(s):  
Anika Tasnim ◽  
AKM Shamsuzzaman ◽  
Md Shah Alam ◽  
Jannatul Ferdose ◽  
Fazlay Akbar Khan

Background: Patients of burn wound are generally more susceptible to infection due to concurrent status of malnutrition and immunosuppression. Among many bacteria, MRSA has appeared as a challenging pathogen irrespective of effective antibiotic therapy. Objective: The purpose of the present study was to detect the prevalence and antibiogram of MRSA in burn wound infected patients. Methodology: The present cross sectional study was conducted at Department of Microbiology in Rajshahi Medical College, Rajshahi, Bangladesh. The samples were collected from Burn and Plastic Surgery Unit of Rajshahi Medical College Hospital, for a period of one year. Phenotypic detection of MRSA were done by cefoxitin disc diffusion method and genotype (mecA gene) was detected by PCR which was conducted at Dhaka Medical College, Dhaka among all the S. aureus isolates. Result: A total of 212 wound swabs were subjected to bacteriological culture media for isolation of MRSA and other organisms. As a whole 89.62% samples yielded growth in culture of which Pseudomonas aeruginosa was the predominant pathogen (34.18%). Out of 21 S.aureus isolates, 07(33.33%) were detected as MRSA by cefoxitin resistance and presence of mecA gene. Although over 85% MRSA were resistance to ciprofloxacin and ceftriaxone, but the present study could not detect any vancomycin resistant MRSA. Conclusion: The high prevalence and decreased sensitivity of MRSA to commonly used antibiotics has been observed in Burn Unit of RMCH. Therefore it is necessary to establish an antimicrobial surveillance system in hospital settings to prevent the spread of MRSA. Bangladesh Journal of Infectious Diseases 2020;7(1):12-17


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