scholarly journals A Comparative Study Among Different Invasive Methods For The Diagnosis Of Helicobacter Pylori

1970 ◽  
Vol 5 (1) ◽  
pp. 21-24
Author(s):  
MDU Islam ◽  
SHZ Rahman ◽  
SM Shamsuzzaman ◽  
N Muazzam ◽  
SG Kibria ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Rapid Urease Test ◽  
World Population ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Diagnostic Endoscopy ◽  
Urease Test ◽  
H Pylori

H. pylori infection occurs worldwide. Approximately 50% of the world population is infected with this organism. A cross-sectional study was conducted on 81 dyspeptic patients attending at Dhaka Medical College Hospital, for diagnostic endoscopy. H. pylori infection was measured by three invasive methods: culture, rapid urease test & histopathology. Among study patients maximum (34.57%) H. pylori infected were in 21-30 years age group, bearing male female ratio 1: 92.86. Forty four (54.32%) out of 81 were culture positive, 61 (75.31%) were rapid urease test positive and 62 (76.54%) were histopathology positive. By using 'gold standard' definition, 64 (79.02%) were H. pylori infected, 17 were un-infected. Finally comparing among three invasive methods, all are highly sensitive and specific to diagnose H. pylori infection. DOI: 10.3329/fmcj.v5i1.6809Faridpur Med. Coll. J. 2010;5(1):21-24

scholarly journals Comparison of IL-6, IL-8 Concentrations in H. pylori- and non-H. pylori-associated Gastritis

2014 ◽  
Vol 6 (3) ◽  
pp. 163 ◽  
Author(s):  
Gontar Alamsyah Siregar ◽  
Sahat Salim ◽  
Ricky Rivalino Sitepu
Keyword(s):  
Helicobacter Pylori ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Bivariate Analysis ◽  
Rapid Urease Test ◽  
Serum Samples ◽  
Cross Sectional ◽  
Non Invasive ◽  
Urease Test ◽  
H Pylori

BACKGROUND: Helicobacter pylori is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. The gastric mucosal levels of the proinflammatory cytokines Interleukin 6 (IL-6) and IL-8 have been reported to be increased in H. pylori infection, but the serum levels in H. pylori infection is still controversial. The purpose of this study was to investigate the serum levels of IL-6 and IL-8 in H. pylori infection.METHODS: A cross sectional study was done on eighty consecutive gastritis patients admitted to endoscopy units at Adam Malik General Hospital and Permata Bunda Hospital, Medan, Indonesia from May-October 2014. Histopathology was performed for the diagnosis of gastritis. Rapid urease test for diagnosis of H. pylori infection. Serum samples were obtained to determine circulating IL-6 and IL-8. Univariate and bivariate analysis (independent t test) were done.RESULTS: There were 41.25% patients infected with H. pylori. Circulatory IL-6 levels were significantly higher in H. pylori-infected patients compared to H. pylori negative, but there were no differences between serum levels of IL-8 in H. pylori positive and negative patients.CONCLUSION: The immune response to H. pylori promotes systemic inflammation, which was reflected in an increased level of serum IL-6. Serum levels of IL-8 were not significantly different between H. pylori positive and negative.KEYWORDS: Helicobacter pylori, gastritis, IL-6, IL-8, cytokine

scholarly journals GENDER, AGE, ENDOSCOPIC FINDINGS, UREASE AND HELICOBACTER PYLORI: ALL UNCORRELATED WITHIN A SAMPLE OF A HIGH GASTRIC CANCER PREVALENCE POPULATION IN AMAZON

2019 ◽  
Vol 56 (3) ◽  
pp. 264-269
Author(s):  
Ariney Costa de MIRANDA ◽  
Cássio CALDATO ◽  
Mira Nabil SAID ◽  
Caio de Souza LEVY ◽  
Claudio Eduardo Corrêa TEIXEIRA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cross Sectional Study ◽  
Upper Gastrointestinal Endoscopy ◽  
Histopathological Analysis ◽  
Rapid Urease Test ◽  
Cross Sectional ◽  
Cancer Prevalence ◽  
Urease Test ◽  
H Pylori

ABSTRACT BACKGROUND: It is widely assumed that gender, age, gastritis and Helicobacter pylori , all have some degree of correlation and, therefore, can synergistically lead to the development of gastric cancer. OBJECTIVE: In this cross-sectional study, we expected to observe the above mentioned correlation in the analysis of medical records of 67 patients of both sexes (female, n=44), mean age ± standard deviation: 41±12 years old, all from Belém (capital of Pará State, Brazilian Amazon), a city historically known as one with the highest gastric cancer prevalence in this country. METHODS: All patients were submitted to upper gastrointestinal endoscopy for gastric biopsy histopathological analysis and rapid urease test. All diagnoses of gastritis were recorded considering its topography, category and the degree of inflammatory activity, being associated or not associated with H. pylori infection. RESULTS: The results show that no statistically relevant associations were found among the prevalences of the observed variables. CONCLUSION: The authors hypothesize that observed risk factors associated to gastric cancer might be lesser synergistic than is usually expected.

scholarly journals H.PYLORI INFECTION

2016 ◽  
Vol 23 (03) ◽  
pp. 307-311
Author(s):  
Shabnam Naveed ◽  
Syed Masroor Ahmed ◽  
Zeeshan Ali ◽  
Romana Awan ◽  
Humaira Zakir ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Gastric Ulcer ◽  
Cross Sectional Study ◽  
Rapid Urease Test ◽  
Viral Etiology ◽  
Cross Sectional ◽  
Urease Test ◽  
Cirrhotic Patients ◽  
H Pylori ◽  
Study Setting

Objectives: To study the frequency of H. pylori infection and its association as acause of upper G.I bleeding in cirrhosis. Study Design: Cross Sectional Study. Setting: MedicalUnit III, JPMC Karachi. Period: January 2014 to December 2014. Methods: 100 patients ofestablished cirrhosis with upper G.I bleeding were included in this study. These patients wereevaluated for viral etiology of cirrhosis. An upper G.I Endoscopy was performed in all patientsand antral biopsies were taken. Rapid urease test was performed on biopsy specimen fordetection of H.pylori infection. Results: Out of 100 patients 71 were males and 29 were femaleswith age ranging between 14 to 70 years. Among them 53% patients turned out to be positivefor H.Pylori infection with rapid urease test. H.pylori infection was detected in 68.7% of HBsAgpositive patients and in 50% of Anti HCV positive patients. On upper G.I endoscopy 96 patientshad PHG and among them 50 (52%) were positive for H.pylori. 4 patients did not have PHGand among them 3 (75%) were positive for H.pylori. Gastric ulcer was present in 17 patientsand amongst them H.pylori was detected in 10 (58.8%) cases. Duodenal ulcer was present in 5patients and among them 2 (40%) were positive for H.pylori. Gastritis was present in 17 casesamong them 11 (64%) were positive for H.pylori. Duodenitis was present in 13 cases amongthem 11 (84.6%) patients were positive for H.pylori infection. Conclusion: The frequency ofH.pylori infection was low in cirrhotic patients. No association was seen in H.pylori infectionand causes of upper G.I bleeding in cirrhosis including PHG, gastric ulcer and duodenal ulcer

Age, Gender and Common Site of Haematoma Formation among Acute Subdural Hematoma Patients: Experience of 48 Cases in Bangladesh

2021 ◽  
Vol 17 (2) ◽  
pp. 54-57
Author(s):  
Kalim Uddin ◽  
Md Abdus Salam ◽  
Ashraful Haque ◽  
Amir Md Khan ◽  
Md Mahfuzur Rahman ◽  
...  
Keyword(s):  
Subdural Hematoma ◽  
Cross Sectional Study ◽  
Acute Subdural Hematoma ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Male And Female ◽  
Medical College ◽  
And Gender ◽  
One Year

Background: Acute subdural hematoma can occurs in different age group of patients in both male and female. Objective: The purpose of the present study was to observe the age and gender distribution among acute subdural hematoma patients. Methodology: This cross-sectional study was carried out in the Neurosurgery Department of Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2011 to August 2012 for a period of one year and eight months. Patients with acute subdural hematoma who fulfil the inclusion criteria for surgery and got admitted were selected as study population. Acute Subdural hematoma patient of any age, both sex with GCS 5 to 13, thickness of hematoma more than l0 mm, midline shift more than 5 mm, pupil reacting to light and patient presented within 72 hours of injury were included for this study. At admission, a detailed history of the illness was taken from the patient or attendant, thorough general and neurological examinations were carried out and were recorded. Result: A total number of 48 patients were recruited for this current study. The mean age of the patients was 32.39±11.63 years and their age ranged from 10 to 56 years. The male and female ratio was 5:1. Out of 48 patients 17(31.25%) cases were fronto-temporal. Temporo-parietal were 16(33.3%) patients. Fronto-temporo-parietal were 7(14.5%) cases. Parietal were 5(10.41%) cases. Frontal were 3 (6.25%) case. Conclusion: In conclusion majority of the patients are male young adults presented with fronto-temporal and temporo-parietal region of shull. Journal of Science Foundation 2019;17(2):54-57

scholarly journals Presentation of sinonasal carcinoma

2014 ◽  
Vol 19 (2) ◽  
pp. 99-103
Author(s):  
Md Momenul Haque ◽  
Mohammad Idrish Ali ◽  
Md Harun-Ar-Rashid ◽  
Md Tariqul Islam ◽  
Mujibur Rahman ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Economic Condition ◽  
Neck Surgery ◽  
Cross Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Sinonasal Carcinoma ◽  
Age Limits

Objective: To observe the pattern of clinical presentation according to site of origin of sinonasal carcinoma. Methods: This cross-sectional study was done in the Department of Otolaryngology-Head and Neck Surgery, BSMMU and Dhaka Medical College Hospital, Dhaka during the period from January 2008 to December 2009. Patients of sinonasal carcinoma were evaluated by detailed history, clinical examination and relevant investigations. Results: The present study included 40 patients of sinonasal malignancy bearing age limits of 4 years to 75 years with mean age 48.29. Male and female ratio was 2.6:1. Most patients (77.5%) came from rural area and illiterate (40%) and most of them were farmers (40%), having poor socio-economic condition (50%). About 35% of them were smokers and more than one other personal habit. Majority patients presented with multiple sinuses involvements (72.5%) and among single sinus involvement maxillary sinus was most common (63.63%), followed by nasal cavity (27.27%) and ethmoidal sinus (9.09%) as primary site. Conclusion: Though carcinoma of the nose and paranasal sinuses is relatively uncommon, it is not uncommon in our country. This disease generally presents in an advanced stage. Overall prognosis was directly related to diseases stages. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17632 Bangladesh J Otorhinolaryngol 2013; 19(2): 99-103

scholarly journals Performance of CT Scan in diagnosis of Sinonasal mass

2019 ◽  
Vol 24 (2) ◽  
pp. 149-155
Author(s):  
Lodh Dipankar ◽  
Islam Nazmul ◽  
Talukder Debesh ◽  
Majumder Rita ◽  
Arafat Shahriar ◽  
...  
Keyword(s):  
Ct Scan ◽  
Histopathological Examination ◽  
Malignant Tumour ◽  
Cross Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Sinonasal Mass ◽  
Histopathological Results

Objective: To establish CT scan as a sensitive modality in the diagnosis of sinonasal mass by correlating with the findings of histopathological examination Methods: This cross sectional study was conducted in Dhaka Medical College Hospital (DMCH) from 01/07/2013 to 30/06/2014. A total of 32 cases were studied. Results: In this study male and female ratio was 1.4:1. So, the incidence of sinonasal mass slightly higher in male (59.3%) compared to the female (40.6%). Incidence of malignant tumour was found more in age group above 60 years. Out of 32 patients, 6 patients (18.7%) were diagnosed histopathologically as infective, 7 patients (21.8%) were benign and 19 patients (59%) had malignant sinonasal mass. Conclusion: Computed tomography (CT) scan examination of the sinonasal mass correlate well in most of the cases with histopathological results. It is therefore can be concluded that CT examination of nose and paranasal sinuses is a useful modality in the evaluation of sinonasal mass.  Bangladesh J of Otorhinolaryngology; October 2018; 24(2): 149-155

scholarly journals Comparative Study of Ultrasound Guided FNAC and Conventional FNAC in the Diagnosis of Parotid Tumour

2015 ◽  
Vol 21 (1) ◽  
pp. 5-16
Author(s):  
Mohammad Obaidul Islam ◽  
Md Zakaria Sarker ◽  
Muddassir Mahmud ◽  
Mesbah Uddin Ahmed ◽  
Ashequr Rahman Bhuiyan ◽  
...  
Keyword(s):  
Imaging Modality ◽  
Cross Sectional Study ◽  
Clinical Feature ◽  
Parotid Tumor ◽  
Ultrasound Guided ◽  
College Hospital ◽  
Cross Sectional ◽  
Predictive Values ◽  
Female Ratio ◽  
Medical College

Objective: To evaluate role of ultrasound guided FNAC for the diagnosis of parotid tumor.Methods: This cross sectional study was conducted in 39 patients with parotid tumor admitted in the ENT department of out door of Bangabandhu Sheikh Mujib Medical University, Dhaka Medical College Hospital, and Sir Salimullah Medical College and Mitford Hospital Dhaka, during July 2013 to June 2014 were enrolled for surgical management. Conventional FNAC and ultrasound guided FNAC were done in all these patients and they were followed up from the admission upto the post operative tissue diagnosis of parotid tumor in respective pathology departments for histopathological correlation.Results: The highest incidence of parotid tumor was in 4th decade and male to female ratio was almost 1:1. The main clinical feature were 27(69.2%) had firm, 6(15.4%) soft, 1(2.6%) hard and 5(12.8%) over the parotid tail. The validity of histopathology evaluation for pleomorphic in USG FNAC sensitivity 95.7%, specificity 100.0%, accuracy 97.4%, positive predictive values 100.0%, negative predictive values 94.1%. Evaluation for Meucoepidermoid sensitivity 80.0%, specificity 97.1%, accuracy 94.9%, positive predictive values 80.0%, negative predictive values 97.1% in USG FNAC. In USG FNAC for identification Warthin sensitivity 100.0%, specificity 100.0%, accuracy 100.0%, positive predictive values 100.0%, negative predictive values 100.0%. Evaluation for Adenocystic in USG FNAC sensitivity 100.0%, specificity 100.0%, accuracy 100.0%, positive predictive values 100.0%, negative predictive values 100.0%.Conclusion: It can be concluded that Ultrasound guided FNAC has definite value in the diagnosis of tumours and can be regarded as a sensitive and specific imaging modality for pre-operative discrimination of the benign and malignant parotid tumours.Bangladesh J Otorhinolaryngol; April 2015; 21(1): 5-16

scholarly journals Prevalence of Helicobacter Pylori Genotypes and Their Association with Upper Gastrointestinal Diseases: A Cross Sectional Study in Southern Iran

2021 ◽  
Author(s):  
Rahim Raufi ◽  
Reza Shahriarirad ◽  
SeyedehMaryam Pishva ◽  
Nikta Taghipour
Keyword(s):  
Helicobacter Pylori ◽  
Hiatal Hernia ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Rapid Urease Test ◽  
Cross Sectional ◽  
Southern Iran ◽  
Normal Esophagus ◽  
Urease Test ◽  
H Pylori

Abstract Background: Investigating the prevalence of vacuolating cytotoxin (vacA), cytotoxin associated gene A (cagA), glm M genotypes, and subtypes of vacA of Helicobacter pylori (H. pylori) isolate in Jahrom, Southern Iran.Methods: DNA extracted from H. pylori samples retrieved from gastric biopsy isolated from 113 dyspeptic patients with positive rapid urease test (RUT). Genotyping was done by polymerase chain reaction (PCR) technique, using primers for vacA (s1a, s1b, s1c, s1, s2, m2, and m1), cagA, and glmM. Endoscopy was done for all the patients to screen gastrointestinal (GI) pathologies. Results: GlmM was detected in 100% of the cases. VacA subtypes s1am2, s2m2, s1am1, s1b, and s1c were detected in 27.9%, 25.6%, 22.1%, 3.5% and 2.4% of the isolates, respectively, while cagA was detected in 60.5% of the isolates. VacA alleles m1, s1, and s2 were detected in 54%, 50%, and 44% of isolates, respectively. Also, 60.5% of the isolates were cagA-vacA-positive. A significant correlation was observed between vacAs1bm1 and gastroesophageal reflux disease (GERD), and glmM positive isolates had normal esophagus. The presence of vacAs1bm1 and vacAs1bm2 has a significant association with gastric erythema. The presence of cagA showed a significant association with normal esophagus and hiatal hernia.Conclusion: In our research, the number of glmM and cagA positive isolates is higher among other genotypes, and cagA is correlated with hiatal hernia, and normal esophageal finding is correlated with glmM genotype. There was no association between the age or sex of the patients and bacterial genotype.

scholarly journals Clinicopathological Study on Hypopharyngeal Carcinoma in Dhaka Medical College Hospital

2016 ◽  
Vol 21 (2) ◽  
pp. 85-89
Author(s):  
Md Nazmul Islam ◽  
Dipankar Lodh ◽  
Mohammad Mamun Siddiqui ◽  
AF Mohiuddin Khan ◽  
Kazi Meherunnesa
Keyword(s):  
Neck Surgery ◽  
Cross Sectional Study ◽  
Neck Mass ◽  
Medical College Hospital ◽  
Hypopharyngeal Carcinoma ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio

A Cross-Sectional Study was carried out from July 2006 to June 2007 at Department of Otolaryngology and Head-Neck Surgery of Dhaka Medical College Hospital, Dhaka. Data was collected from 150 patients with histologically diagnosed Hypopharyngeal carcinoma. Results of this study showed that hypopharyngeal carcinoma affects more in fifth (36.7%) and sixth (27.4%) decades of life. It was found that male were highly predominant to develop hypopharyngeal carcinoma and male female ratio was 9:1. People with lower educational level were found to be affected more by hypopharyngeal carcinoma. In this study 86 percent patients had history of smoking. Mean duration of smoking was 38.0±23.6 years. This study found that the key symptoms of hypopharyngeal carcinoma was dysphagia, pain and neck mass. In this study 83.5 percent patients presented with palpable lymph node and most (76.6%) of them were in level II. Pyriform fossa was found to be the commonest site (83.3%). In this study all malignancy in hypopharynx was histopathologically squamous cell carcinomaBangladesh J Otorhinolaryngol; October 2015; 21(2): 85-89

scholarly journals Utility of Rapid urease test in diagnosis of Helicobacter pylori infection

2019 ◽  
pp. 4417-4422
Author(s):  
Shaan Khetrapal ◽  
Samarth Shukla ◽  
Safia Rana ◽  
Zeeba S Jairajpuri ◽  
Sourya Acharya
Keyword(s):  
Helicobacter Pylori ◽  
Cross Sectional Study ◽  
Helicobacter Pylori Infection ◽  
Rapid Urease Test ◽  
Cross Sectional ◽  
Intestinal Lesions ◽  
Common Diagnosis ◽  
Urease Test ◽  
H Pylori ◽  
Haematoxylin And Eosin Stain

Aim: To evaluate the role of rapid urease test in diagnosis of Helicobacter pylori infection in various gastro intestinal lesions vis a vis conventional and special staining methods. Materials & Methods: This hospital based cross sectional study was conducted on 50 cases with gastro intestinal lesions.  The obtained biopsies were then subjected to rapid urease test for detection of H. pylori by using the Pronto Dry Kit immediately. Further histopathology examination using conventional H & E (haematoxylin and eosin) stain and special Gimenez stain for H. pylori was done. Results: In this study gender wise distribution of patients showed 58% males and 42% females. Chronic gastritis was found to be the most common diagnosis (28%), followed by squamous cell carcinoma (20%) chronic inflammation (16%), H. pylori gastritis and adenocarcinoma stomach (6%), adenocarcinoma esophagus, dysplasia, erosion, esophagitis and perforation in 4%. Least common diagnosis was atrophic gastritis and carcinoid in 2%. We found that 26 cases were positive for H. pylori with Rapid urease test and 24 with special stain (Gimenez). Conclusion: This study amalgamates and incorporates the valuable clinical assessment along with the endoscopic findings, the surgical pathological (histopathology) evaluation of the biopsies along with the proto dry kit (rapid urease test), as a kind of “Gastric Triple Test” for declaring the patients as positive or negative for pathogenic infection with Helicobacter pylori.

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