scholarly journals Serum chromium and selenium levels in type 2 diabetes mellitus

2018 ◽  
Vol 12 (2) ◽  
pp. 72-75
Author(s):  
Hossneara Eva ◽  
Qazi Shamima Akhter ◽  
Md Khairul Alam ◽  
Shahriar Ahmed

Background: Emerging evidence suggests that several trace elements such as serum chromium (Cr) and selenium (Se) levels are altered in type 2 DM and its deficiencies are associated with the development of diabetes related complications.Objective: To assess the serum Cr and Se levels in patients of type 2 diabetes mellitus.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2014 to June 2015. Fifty type 2 diabetic patients with age ranging from 40 to 55 years were study group and fifty ages, BMI matched healthy subjects were control group. Patients were selected from Bangladesh Institute of Research for Diabetic Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka. Serum Cr and Se levels were estimated by flame atomic absorption spectrophotometry. For statistical analysis unpaired Student’s‘t’ test and Chi square test were performed.Results: In this study, serum Cr and Se levels were significantly (P<0.001) lower in patients than that of control group. In addition 20% patients had low Cr and 16% had Se deficiencies. Moreover, 6% of control had low Cr and 4% had low Se.Conclusion: From this study, it is concluded that serum Cr and Se deficiencies are associated with type 2 diabetes mellitus.Bangladesh Soc Physiol. 2017, December; 12(2): 72-75

2016 ◽  
Vol 11 (2) ◽  
pp. 50-53 ◽  
Author(s):  
Hossneara Eva ◽  
Quzi Shamima Akhter ◽  
Md Khairul Alam

Background: Serum level of several trace elements such as zinc (Zn) and manganese (Mn) levels are altered in type 2 DM and its deficiencies are associated with the development of microvascular and macrovascular complications.Objective: To assess the serum zinc (Zn) and manganese (Mn) levels in subjects with type 2 diabetes mellitus.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2014 to June 2015. Fifty type 2 diabetic subjects with age ranging from 40 to 55 years of both sexes were study group and 50 age, sex and BMI matched healthy subjects were control group. Patients were selected from Bangladesh Institute of Research for Diabetic Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka. Serum Zn and Mn levels were estimated by flame atomic absorption spectrophotometry. For statistical analysis, unpaired Student’s‘t’ test and chi square test was performed.Results: In this study, mean serum zinc and manganese levels were significantly (P<0.001) lower in the study group than that of control group. In addition, hypozincemia in 36% and hypomanganesemia in 18% of diabetic patients were observed and which was significantly (p<0.001) higher than those of control.Conclusion: From this study, it may be concluded that serum zinc and manganese deficiencies may develop as diabetes related complications.Bangladesh Soc Physiol. 2016, December; 11(2): 50-53


PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253286
Author(s):  
Mesay Arkew ◽  
Tilahun Yemane ◽  
Yordanos Mengistu ◽  
Kabtamu Gemechu ◽  
Girum Tesfaye

Background Diabetes is a global public health problem and associated with metabolic, cellular, and blood disturbances. Hematological changes have been reported in diabetes and play a major role in diabetes-associated complications. However, reports are contradicting and data on hematological parameters of type 2 diabetic patients in the study area are scarce. Therefore, the aim of this study was to assess the hematological parameters of type 2 diabetic adult patients at Debre Berhan Referral Hospital, Northeast Ethiopia from May 01 to June 30, 2020. Methods A comparative cross-sectional study was conducted on 268 (134 type 2 diabetic patients and 134 controls) study participants selected by systematic random sampling technique. Socio-demographic, behavioral, and clinical data were collected using a structured questionnaire and checklist. Ethical approval was obtained from Jimma University. All phase of quality assurance was maintained. Hematological parameters and blood glucose levels were determined using UniCel DxH 800 (Beckman Coulter, USA) and Biosystems A25 (Costa Brava, Spain) analyzers, respectively. Independent t-test, Mann–Whitney U-test, correlation, and logistic regression were used during data analysis. P-value <0.05 was considered as statistically significant. Results The current study found that total white blood cell count, absolute counts of neutrophil, lymphocyte, eosinophil, and basophil, red blood cell distribution width, platelet count, and mean platelet volume were significantly higher in type 2 diabetic patients as compared to the control group (P<0.05). On the other hand, the mean hemoglobin was significantly lower in type 2 diabetic patients than the control group (P = 0.007). Anemia was found in 17.9% of type 2 diabetic patients. Longer duration of diabetes (AOR = 3.05, 95% CI = 1.12–8.34) and milk consumption (AOR = 4.60, 95% CI = 1.50–14.00) were significantly associated with anemia. Conclusion This study showed a statistically significant variation in some hematological parameters of type 2 diabetic patients compared to control group. Anemia among type 2 diabetic patients was found to be a mild public health problem. Therefore, routine screening of hematological parameters should be considered for proper management of type 2 diabetic patients. Close attention should also be given to the duration of diabetes and dietary practice.


Author(s):  
Raana Gholamzadeh Nikjoo ◽  
Haniye Nikbakht ◽  
Yegane Partovi ◽  
Tohid Jafari Koshki

Background: One of the most common chronic diseases is diabetes, which self-care has a very significant role in reducing its complications. The aim of this study was to investigate the effect of social and economic factors on the attitude of diabetic patients towards self-care behaviors. Methods: The current study is a cross-sectional study conducted in 2019. The sample included 170 patients with diabetes referring to the clinics affiliated to the Tabriz University of Medical Sciences. Data were collected using a previously developed questionnaire through interview. Results: Out of participants in the study, had a positive attitude towards self-care behaviors of type 2 diabetes. We observed significant association between attitude towards self-care behaviors in type 2 diabetes and membership in real and virtual groups (P < 0.001), education (P < 0.001) support of family members (P < 0.001), household income (P = 0.01). Conclusion: Regarding the correlation between certain social and economic variables, and patient attitude towards self-care in diabetes, as well as the effects of attitude in performing self-care behaviors, and the beneficial results of these behaviors in disease control, correct methods must be adapted to control these variables both materially and spiritually. Some of the methods suggested by the researchers are holding frequent educational classes for these people, providing suitable pamphlets, allocating suitable environments and green spaces for diabetic patients, creating suitable and fun virtual groups, identifying type 2 diabetic patients who are not supported by families or do not have enough income and creating suitable group spaces for these people.


2020 ◽  
Vol 62 (1) ◽  
Author(s):  
Lộc Ninh Tô ◽  
Văn Mãi Đỗ ◽  
Đặng Minh Trí Bùi ◽  
Quốc Thắng Trần

Objective: To assess compliance and some factors related to medicine use of patients with type 2 diabetes mellitus at Nam Can District General Hospital, Ca Mau Province. Objects and methods: Cross-sectional study on 528 outpatients with type 2 diabetes treatment at Nam Can District General Hospital, Ca Mau province from July 2019 to April 2020. Results: Adherence rate to drug use in type 2 diabetic patients: 40 patients (7.6%) had high compliance level with using medicine, 274 patients had moderate compliance level (51.9%) and 214 patients had poor compliance level (40.5%). There was one factor related to drug adherence: occupation (OR = 0.053; 95% CI = 0.372-1.007. Conclusion: mainly patients with moderate and low compliance levels. Occupation was related to compliance of using medicine.


Author(s):  
P. S. Vignesh ◽  
T. T. Gopinath ◽  
D. K. Sriram

Background: Diabetes mellitus (DM) is a chronic and potentially disabling disease which is reaching an epidemic proportion in many parts of the world. UTI is a common infection observed in diabetic patients. The objectives of this study was to determine the prevalence of UTI among hospitalized type 2 diabetic patients, the frequent bacteria responsible for UTI and most susceptible antibiotics among the diabetic patients.Methods: A hospital-based study involving type 2 diabetes patients admitted with diagnosis of UTI between 2017- 2018 (July - June). The study was a cross sectional study and was approved by the Ethics Committee of the hospital. Patients fitting study inclusion and exclusion criteria took part in the study with informed written consent obtained. A validated pilot-tested questionnaire was used as a tool for data collection.Results: Total of 126 subjects were identified. Prevalence of UTI was around 25% higher in women with type 2 diabetes than in men. UTI was found to be significantly associated with age, creatinine (p<0.05) and Escherichia coli was the commonly isolated micro-organism. The gram negative pathogens were highly sensitive to cefoperazone-sulbactum and amikacin was found to be the most sensitive antibiotic for both gram positive and gram negative pathogens.Conclusions: UTIs are frequent in diabetic patients. Improved glycemic control in diabetics may help in controlling the UTIs. Accurate screening for UTI in diabetic patients is also critical to enable the appropriate treatment and avoiding related complications.


2021 ◽  
Vol 59 (236) ◽  
Author(s):  
Ram Kumar Mehta ◽  
Puru Koirala ◽  
Ram Lala Mallick ◽  
Surya Parajuli ◽  
Rajneesh Jha

Introduction: Dyslipidemia is highly prevalent among type 2 diabetic patients. It increases the risk of atherosclerosis and consequent mortality in diabetic patients. The aim of this study was to find out the prevalence of dyslipidemia among type 2 diabetic patients. Methods: This was a descriptive cross-sectional study in 355 type 2 diabetic patients at tertiary care hospital from 15th May, 2020 to 15th November, 2020 after taking ethical clearence from Institutional Review Committee (Reference no. IRC-PA-052/2077-78). Convenience sampling was done. Demographic and lipid profile variables were recorded based on the structured questionnaires. Data were analyzed by Statistical Package for the Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: Out of total 355 cases of type 2 Diabetes mellitus, prevalence of dyslipidemia was 224 (63.1%). It was more prevalent in male 145 (69.4%) than female 79 (54.1%). Increased Low density Lipoprotein (94.2%) was the most prevalent type followed by mixed dyslipidemia (91.1%). Conclusions: Dyslipidemia was common among type 2 diabetic patients and was higher in male gender, older age, obesity and longer duration of diabetes. Hence type 2 diabetic patient should undergo the routine monitoring of blood sugar and lipid profile so that any abnormalities can be identified and preventive measures along with interventions can be initiated at the earliest.


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