scholarly journals Frequency of Transfusion Transmitted Infection Among Blood Donors at Specialized Tertiary Care Hospital in Bangladesh

2015 ◽  
Vol 1 (1) ◽  
pp. 12-14
Author(s):  
Ferdous Ara ◽  
Zubaida Nasreen ◽  
Md Aminul Islam ◽  
Md Abdullah Yusuf ◽  
Mohammad Syaeed Hassan ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Venereal Disease ◽  
Tertiary Care ◽  
Malarial Parasite ◽  
Care Hospital ◽  
Transmitted Infection ◽  
Major Health Problem ◽  
The Status

Background: Blood transfusion is associated with a number of complications. Transfusion transmitted infections (TTI) are one of the major health problem in Bangladesh.Objective: The objective of the present study was to assess the status of transfusion transmitted infections among the apparently healthy donors.Methods: This study we carried out among 585 blood donors in the transfusion medicine department from April 2013 to March 2014 at National Institute of Neurosciences (NINS) and Hospital in Dhaka, Bangladesh. All the samples were screened for hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2, venereal disease research laboratory test (VDRL) and malaria to see the prevalence of TTI.Results: Prevalence of hepatitis B virus (HBV), HCV, and syphilis were 1.20, 0.68 and 0.34% respectively. No blood donor tested showed positivity for malarial parasite and HIV.Conclusion: Mandatory screening of donated blood and use of sensitive screening test should be done to reduce TTI in Bangladesh.J. Natl Inst. Neurosci Bangladesh 2015;1(1):12-14

scholarly journals Prevalence of Transfusion Transmitted Infection among Blood Donors at Medical University in Bangladesh

2017 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Ferdous Ara ◽  
ABM Mashiul Alam ◽  
Manjuma Rahman ◽  
Asifa Jahan ◽  
Abdullah Yusuf ◽  
...  
Keyword(s):  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Venereal Disease ◽  
Transmitted Infection ◽  
Major Health Problem ◽  
Transfusion Transmitted Infection ◽  
Immunodeficiency Virus ◽  
The Status ◽  
Donated Blood ◽  
Medical University

Background: Blood transfusion is associated with a number of complications. Transfusion transmitted infections (TTI) are one of the major health problem in Bangladesh.Objective: The objective of the present study was to assess the status of transfusion transmitted infections among the apparently healthy donors.Methodology: This study we carried out among 12,294 blood donors from September 2009 to March 2010 at Department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. All the samples were screened for hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2, venereal disease research laboratory test (VDRL) and malaria to see the prevalence of TTI.Results: Prevalence of HBV, HCV, HIV, and syphilis were 0.009, 0.0004, 0.0001 and 0.0001% respectively. No blood donor tested showed positivity for malarial parasite.Conclusion: Mandatory screening of donated blood and use of sensitive screening test should be done to reduce TTI in Bangladesh.J Shaheed Suhrawardy Med Coll, June 2014, Vol.6(1); 11-13

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

SERO PREVALENCE OF TRANSFUSION TRANSMITTED INFECTIONS (TTI) IN VOLUNTARY BLOOD DONORS IN A TERTIARY CARE HOSPITAL AT SRINAGAR

2021 ◽  
Vol 5 (5) ◽  
Author(s):  
Nadia Shafi Chickan ◽  
Altaf Hussain Mir ◽  
Masaratt-ul Gani ◽  
Shazia Handoo ◽  
Farooq Ahmad Ganie
Keyword(s):  
Health Care ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Care Facility ◽  
Health Care Facility ◽  
Care Hospital ◽  
Serum Samples

Introduction: Blood transfusion plays an vital role in patients management and is live saving in my instances. it plays a pivotal role as a specialized modality of treatment and saves millions of lives worldwide each year and reduces morbidity. Stringent screening of blood not only ensure safe supply of blood and blood products, but also gives us idea about prevalence of ttis among general population Objective: to determine the serroperavalance of tti among blood donors in lalded hospital Materials and methods: A retrospective study was carried out over a period of 3 years from January 2017 to December 2019.serum samples were screened for hepatitis B surface antigen ,antibodies to human immunodeficiency virus Type 1 and 2 ,hepatitis c virus and syphilis in department of transfusion medicine was carried out Result: The result shows that 55 (3.72%) of the blood donors had TTIs. The prevalence of Hepatitis B, Hepatitis C, Malaria, Syphilis and Human immunodeficiency viruses (HIV), was found to be 31(0.21%), 23 (0.15%), 01 (0.0.006%), 01 (0.006%) and 02 (0.0.23%) respectively. None were positive for malaria. Conclusion: Transfusion Transmittable Infections pose a threat to patients admitted in any health care facility and if not carefully screened for will cause significant morbidity. Careful screening of all donor blood units in the blood bank of a hospital is absolutely necessary to prevent any untoward incidence of TTI in patients admitted to a health care facility Keywords: Transfusion, Sero-Prevalence, Donors, Transfusion Transmissible Infections.

The seroprevalence of HIV, hepatitis B, hepatitis C and venereal disease research laboratory test seropositivity in blood donors: a 5-year retrospective comparative study at tertiary care hospital in Mumbai, Maharashtra, India

2017 ◽  
Vol 5 (6) ◽  
pp. 2662
Author(s):  
Khaneta Parveen ◽  
Abdul Faheem Khan ◽  
Abdul Salim Khan
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Blood Donation ◽  
Venereal Disease ◽  
Tertiary Care ◽  
Seroprevalence Rate ◽  
Care Hospital ◽  
Total Blood ◽  
Retrospective Comparative Study

Background: The high seroprevalence of transfusion-transmitted infectious (TTI) diseases such as HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in India affects the safety of blood for recipients. This study was undertaken with the aim to screen the blood donor’s demographic profile and to estimate seroprevalence of HIV, HBV, HCV and VDRL transmissible by blood transfusion in voluntary and replacement male and female blood donors during the last 5 year period.Methods: The present study was conducted over a period of 5 years (2001-2005) and involved 1,53,020 blood donors including both (voluntary, replacement males and females) who were thoroughly screened and selected for blood donation in blood bank at Departments of Pathology, Seth GS Medical College and KEM hospital, Mumbai, Maharashtra, India.Results: Total five years seropositivity for all four disease marker in all blood donors was 9150 (5.97%). The incidence of HIV seropositivity was 1995 (1.30%), the seroprevalence of HBV in total blood donor was 4673 (3.05%), HCV consist of 1599 (1.04%), and VDRL seropositivity was least, i.e. 883 (0.57%). Out of total 9150 (5.97%) seropositive blood donors, 24 (0.26%) blood donors showed concomitant seropositivity for more than one of the blood transmissible diseases.Conclusions: Seroprevalence rate of all the four blood transmissible diseases was higher in replacement donors, and lower in voluntary group of donors. Therefore, it has been evaluated that the voluntary blood donation is safer and promoted for safe blood donation in comparison to replacement blood donation.

Transfusion Transmissible Infections among Voluntary Blood Donors in a Tertiary Care Hospital, Kerala - A Cross Sectional Study

2021 ◽  
Vol 8 (29) ◽  
pp. 2589-2594
Author(s):  
Raji T.K ◽  
Deepa Narayanan
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Elisa Test ◽  
Malarial Parasite ◽  
Medical Procedure ◽  
Care Hospital ◽  
Blood Products ◽  
Transmissible Infection

BACKGROUND Blood transfusion is a common life-saving medical procedure, but it may cause acute and delayed complications. A transfusion transmissible infection (TTI) is any infection that is transmissible from person-to-person through parenteral administration of blood or blood products i.e. packed red blood cells (RBC), platelets, plasma and other blood products. This study was undertaken to assess the prevalence of transfusion transmissible infections among blood donors in blood bank connected to a tertiary care hospital in Kerala and evaluate the safety of the blood donations. METHODS Samples of 13,262 donors from January to June 2018 were taken. All the donors who were accepted for donation as per criteria by national acquired immunodeficiency syndrome (AIDS) control society were included in the study. Consent was obtained from blood donors to conduct testing for transfusion transmitted diseases. Donors were screened by 4th generation enzyme linked immuno sorbent assay (ELISA) test kits for HIV-1/2, 3rd generation ELISA test kits for HBsAg and hepatitis C virus (HCV), rapid immunochromatographic test for malaria and rapid plasma reagin (RPR) test for syphilis. Tests were performed as per manufacturer instructions. All the reactive samples were discarded as per the guidelines. RESULTS Among 13,262 donors, 13,014 (98.12 %) were males and 248 (1.8%) were females within the age group of 18 - 60 years. Out of these, 7 (0.052%) donors were HBsAg positive and 3 (0.02%) were HIV positive. RPR reactivity was seen in 2 donors (0.01%) only. None of the blood donors tested showed positivity for HCV or malarial parasite. In this study, prevalence of hepatitis B was highest (0.052) followed by HIV (0.02%) and syphilis (0.02%). CONCLUSIONS Hepatitis B virus (HBV) is the most common transfusion transmissible infection among apparently healthy donors, followed by HIV and syphilis. TTI’s can be eliminated or reduced by implementing an integrated strategy for blood safety, like effective selection of blood donors, avoiding unnecessary transfusions, and early detection of TTIs. KEYWORDS Transfusion-Transmitted Infections, HIV, HBV, HCV

scholarly journals Seroprevalence of transfusion transmitted infections in healthy blood donors: A 5-year tertiary care hospital experience

2017 ◽  
Vol 9 (04) ◽  
pp. 283-287 ◽  
Author(s):  
Sushama A. Chandekar ◽  
Gaythri P. Amonkar ◽  
Heena M. Desai ◽  
Nitin Valvi ◽  
Gururaj V. Puranik
Keyword(s):  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Venereal Disease ◽  
Tertiary Care ◽  
Screening Tests ◽  
Care Hospital ◽  
Serum Samples ◽  
Healthy Donors ◽  
Immunodeficiency Virus ◽  
Testing Technology

Abstract INTRODUCTION: Transfusion transmitted infections (TTIs) can cause threat to bloody safety as blood transfusion is an important mode of transmission of TTI to the recipient, hence, to prevent transmission of these diseases, screening tests on blood bags is an important step for blood safety. AIM: This study was undertaken with the aim of determining the seroprevalence of TTI in healthy blood donors in a tertiary care blood bank. MATERIALS AND METHODS: A retrospective study was carried out over a period of 5 years from January 2007 to December 2011. Serum samples were screened for hepatitis B surface antigen (HBsAg), antibodies to human immunodeficiency virus (HIV) Type 1 and 2, hepatitis c virus (HCV) and syphilis using enzyme-linked immunosorbent assays with the third generation kits and venereal disease research laboratory test, respectively. RESULTS: A total of 76,653 healthy donors were included out of which majority of donors were male (91.79%). The overall seroprevalence of HIV, HBsAg, HCV, and syphilis were 0.26%, 1.30%, 0.25%, and 0.28%, respectively. CONCLUSION: Methods to ensure a safety blood supply should be encouraged. For that, screening with a better selection of donors and use of sensitive screening tests including nucleic acid testing technology should be implemented.

scholarly journals Seroprevalence of Hepatitis B and Hepatitis C Virus among Healthy Blood Donors in Tertiary Care Hospital

2018 ◽  
Vol 28 (1) ◽  
pp. 26-31
Author(s):  
SH Pramanik ◽  
Abu Shahin Mohammed Mahbubur Rahman ◽  
Md Nurul Islam ◽  
Md Golam Rabbani ◽  
Md Khalilur Rahman
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Post Transfusion Hepatitis

Hepatitis B virus (HBV) & Hepatitis C virus (HCV) are transfusion transmissible infections. A study was conducted from September, 2015 to March, 2016 at the Transfusion Medicine Department of Rajshahi Medical College Hospital to determine the prevalence of asymptomatic hepatitis B and C virus in apparently healthy blood donors, were subjected to ELISA for screening of hepatitis B surface antigen and Hepatitis C virus. A total of 200 blood donors were screened, the seroprevalence of HBV & HCV infection was 5.0% & 2.0% respectively. The HBV seroprevalence in male donors was 182/8 (4.4%) and in female donors was 18/2 (11.1%). Four donors were found seropositive for HCV giving a seroprevalence of 2%. HCV seroprevalence in male was 182/4 (2.2%) and no female. Seroprevalence of HCV and HBV were higher in younger donors, service holders, married respondents and middle class donors. To reduce the prevalence of post-transfusion hepatitis and stringent donor screening procedure, routine screening for HBV & HCV in blood banks should be performed using more sensitive methods (ELISA).TAJ 2015; 28(1): 26-31

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