scholarly journals Use of Misoprostol in Term pregnant women for Good Delivery Outcome: Experience at a tertiary care Hospital in Dhaka

2016 ◽  
Vol 12 (2) ◽  
pp. 22-26
Author(s):  
Aftabun Nahar ◽  
Rifat Sultana ◽  
Fatema Mahbooba Akter ◽  
Munira Ferdausi ◽  
Md Abdullah Yusuf ◽  
...  

Background: Use of misoprostol in term pregnancy is very useful for the better outcome during delivery. Objective: The purpose of the present study was to see the delivery outcome among the term pregnant women. Methodology: This cohort study was carried out in the Department of Obstetrics and Gynaecology at Sir Salimullah Medical College and Mitford Hospital during the period from 1 st September 2005 to 28th February 2006. Primi or second gravida patients with the gestational age between 37 weeks to 42 weeks in singleton pregnancy with cephalic presentation and not in labour who came for delivery purposes during the study period at any age were selected as study population. After proper selection of the cases, induction of labour (IOL) was done by applying Tab Misoprostol 50mcg in the posterior vaginal fornix. Purpose of induction of labour was successful when vaginal delivery occurred without any untoward side effects and without any surgical interference. Result: Out of 60 pregnant women 21 (35%) patients had unfavourable Bishops' score with 3-5 and 39 (65%) patients had favorable Bishops' score with 6-10. 39 patients had favourable pre- induction cervical score, among them 79% had delivered vaginally and 21% had undergone LUCS. 21 patients had unfavourable cervix, among them 57% experienced vaginal delivery and 43% experienced LUCS. Out of all study population 60% of study population who were primigravide had vaginal delivery in 67% cases and caesarean section in 33% cases and among 40% 2nd gravida cases vaginal delivery was 79% and caesarean delivery was 21%. Conclusion: In conclusion the use of misoprostol during term pregnancy is significantly related with the normal delivery.Journal of Science Foundation 2014;12(2):22-26DOI:  http://dx.doi.org/10.3329/jsf.v12i2.27733

2017 ◽  
Vol 7 (1) ◽  
pp. 6-9
Author(s):  
Aftabun Nahar ◽  
Afroza Ghani ◽  
Serajoom Munira ◽  
Ashia Khatun ◽  
Rifat Sultana ◽  
...  

Background: Use of misoprostol in term pregnancy can give some maternal adverse events.Objective: The purpose of the present study was to see the maternal outcome among the term pregnant women.Methodology: This descriptive, prospective cohort study was carried out in the Department of Obstetrics and Gynaecology at Sir Salimullah Medical College and Mitford Hospital during the period from September 2005 to February 2006. Primi or second gravida patients with the gestational age between 37 weeks to 42 weeks in singleton pregnancy with cephalic presentation and not in labour who came for delivery purposes during the study period at any age were selected as study population. After proper selection of the cases, induction of labour (IOL) was done by applying tablet Misoprostol 5omcg in the posterior vaginal fomix. Purpose of induction of labour was successful when vaginal delivery occurred Without any untoward side effects and Without any surgical interference.Result: A total number of 60 pregnant women were recruited in this study of which 60% patients were within 23-30 years of age. Out of 43 cases of vaginal delivery 22 cases needed 1 dose of Misoprostol 21 cases needed more than 1 dose. 60% of study population who were primigravide had vaginal delivery in 67% cases and caesarean section in 33% cases and among 40% 2nd gravida cases vaginal delivery was 79% and caesarean delivery was 21%.Conclusion: In the conclusion, the use of Misoprostol results in a shorter induction to delivery time, a reduction in the rate of caesarean delivery and also did not appear to produce miserable adverse effects on the method of delivery or the foetus.J Shaheed Suhrawardy Med Coll, 2015; 7(1):6-9


Author(s):  
Radha Kumari Paladugu ◽  
Srinivas Jagath Pentakota ◽  
Sushma N.

Background: Anaemia in pregnancy is now considered as a major public health problem, caused by iron deficiency. WHO has estimated that prevalence of anaemia in developed and developing countries in pregnant women is 14% in developed countries and 51 percent in developing countries and 65-75% in India. Various programmes regarding anaemia prophylaxis and maternal health have been implemented but still the prevalence of anaemia related complications among pregnant women continues to be high. Hence the present study was conducted to study the prevalence and pregnancy outcome as a result of anaemia in a tertiary care center in Visakhapatnam. Methods: A cross sectional descriptive study was carried out from June 2016 to August 2016 in the Department of Obstetrics and Gynecology among postnatal women in King George hospital, Visakhapatnam. A semi-structured questionnaire was prepared and information regarding age, socioeconomic status, parity, gestational age interval between pregnancies and outcome and complication of pregnancy were collected. Results: Mean age of study population is 22.4 years. Out of 100 women involved in the study 65 are from urban areas 29 from rural areas and 6 from tribal areas. Majority of the study population 66% were having HB% between 8-11% i.e. mild anaemia. When Outcome of pregnancy was seen in relation to anaemia majority of the women had live births (90%) followed by 7% IUDs and 2% still births. Conclusions: Majority of the women are in the age group of 20-24 years. Socioeconomic status is directly related to anaemic status of the women. Majority of the women had complication of puerperal sepsis. 


Author(s):  
Akanksha Gupta ◽  
Parul Jain ◽  
Vimala Venkatesh ◽  
Anjoo Agarwal ◽  
D. Himanshu Reddy ◽  
...  

Dengue virus (DENV), chikungunya virus (CHIKV), and Zika virus (ZIKV) are arboviruses that can affect maternal and fetal outcome if acquired during pregnancy. This study was done to estimate the positivity of DENV, CHIKV, and ZIKV in febrile pregnant women attending a tertiary care hospital in north India. Symptomatic pregnant women were tested for these viruses by IgM ELISA and/or by Trioplex real-time polymerase chain reaction. Their symptoms and laboratory parameters were recorded and were followed up till delivery to know their immediate delivery outcome. Of 104 women tested, 50 (48.1%) were positive for viral markers. Of these, evidence of infection by DENV, CHIKV, and both was found in 34 (32.7%), 10 (9.6%), and 6 (5.8%), respectively. ZIKV was not detected in any woman. Maximum DENV positivity occurred in the third trimester of pregnancy and in women residing in urban than rural areas. Chills and rigors, arthralgia, retro-orbital pain, anemia, and vaginal bleeding were more commonly associated with DENV positivity. Backache, arthralgia, jaundice, and vaginal bleeding were more common in CHIKV positives but the difference between positives and nonpositives regarding these symptoms was not statistically significant. Dengue infections were associated with more frequent hospitalizations (OR = 8.38, 95% confidence intervals [CI] = 3.29–21.30) and mortality (OR = 19.0, 95% CI = 1.01–357.10). Hence, to conclude, in India wherever possible, all symptomatic pregnant women should be screened for DENV, CHIKV, and ZIKV as part of sentinel surveillance for ZIKV.


2021 ◽  
pp. 20-25
Author(s):  
Ajit Kumar Nayak ◽  
Manorama Swain ◽  
Sujata Misra ◽  
Manju Kumari Jain

Thyroid disorder is a very common endocrine problem encountered by pregnant women. Maternal thyroid dysfunction is associated with adverse outcome both in mother and fetus. The aim of the study: to find out the prevalence of various thyroid disorders in pregnant women attending antenatal clinic. Materials and methods. This prospective cross-sectional study was carried out in the Department of Obstetrics and Gynecology, F.M. Medical College & Hospital, Balasore, Odisha from June 2020 to May 2021. 220 women with uncomplicated singleton pregnancy were included. Serum Thyroid-stimulating hormone (TSH), free T4 (FT4) and free T3 (FT3) were estimated by using electro-chemiluminescence immunoassay technique. Results. Out of 220 pregnant women screened for thyroid dysfunction, 68 were found to have thyroid disorders. 27.3 % of pregnant women had subclinical hypothyroidism, 1.4 % had overt hypothyroidism, 1.8 % had subclinical hyperthyroidism and 0.5 % had overt hyperthyroidism. Prevalence of subclinical hypothyroidism was 6.36 % when the upper reference limit of TSH level taken as 4 mIU/L. Prevalence of thyroid disorder among pregnant women in the age groups 18–25 years, 26–30 years and 31–40 years were 28.9 %, 32.1 % and 38.9 % respectively. There were 35.5 %, 28 % and 26 % pregnant women with thyroid disorders in the first, second and third trimester respectively. Prevalence of both subclinical and overt hypothyroidism were more in multigravida compared to primigravida. Conclusion. Our study revealed high prevalence of thyroid disorders in pregnant women and maternal subclinical hypothyroidism was the most common pattern.


1970 ◽  
Vol 24 (2) ◽  
pp. 44-49 ◽  
Author(s):  
N Sultana ◽  
S Rouf ◽  
M Rashid

It is sometimes difficult to select the most effective, easy to use, safest, widely accepted and less expensive method for induction of labour and thereby spontaneous vaginal delivery. Prostaglandin E1 analogue ie misoprostol as a successful method both in oral and vaginal form has been used for induction of labour. The present study was conducted with an aim to compare the efficacy and safety of oral and vaginal administration of misoprostol tablets for cervical ripening and induction of labour in pregnant women using similar dosing regimen in two groups of pregnant women. A prospective randomized trial was done on one hundred pregnant women for the purpose. They were between 37 and 42 weeks of gestation with singleton pregnancy, cephalic presentation and unfavourable cervix (modified Bishops score of 4 or less) in the department of Obstetrics and Gynaecology of Dhaka Medical college Hospital during the period between February 2003 and March 2004. The mode of delivery did not vary significantly between the two groups. Mean induction delivery interval, mean doses of misoprostol, number of women delivered within 24 hours, oxytocin requirement and mean time to delivery were nearly similar in the two groups. Only nulliparous women in oral group took longer time to deliver than vaginal group though it was not statistically significant. The mode of delivery also did not differ significantly. The proportion of emergency caesarean section was high in vaginal group than oral group. Neonatal outcome was satisfactory and the results were comparable. (J Bangladesh Coll Phys Surg 2006; 24: 44-49)


Author(s):  
Swati Kagne ◽  
Sambhaji Chate

Background: Disorders of amniotic volume is one of the commonest obstetric problem. Amniotic fluid acts as cushion to the foetus allowing musculoskeletal development and also helps in the differentiation of lungs and gastrointestinal tract. Decreased amniotic fluid, known as oligohydramnios, is known to be associated with adverse perinatal outcome. The objective is to study the maternal and perinatal complications of oligohydramnios in term pregnancy.Methods: The present study was carried out in the Department of Obstetrics at rural tertiary care hospital in Maharashtra from February 2018 through October 2018. women with Oligohyamnios were studied for obstetrical and neonatal complications.Results: The incidence of oligohyamnios was 7.6% in present study. The mean age of the study population was 22.6±3.6 years. Induction of labour was required in 44 (61.11%) patients out of which 23 patients underwent emergency LSCS. Low birth weight (birth weight<2.5kg) was found in 14 (19.44%) babies with 11 babies having intrauterine growth restriction. 5-minute APGAR (appearance, pulse, grimace, activity, respiration) score was <7 in 13.88% babies. 16 babied needed NICU admission out of which 1 neonate died.Conclusions: Detection of oligohydramnios increases obstetrical interventions in term pregnancy.


2021 ◽  
Vol 15 (10) ◽  
pp. 3137-3139
Author(s):  
Mona Fatima ◽  
Urooj Naz ◽  
Aruna Kumari Hira ◽  
Aneela Habib ◽  
Prof Sarah Kazi ◽  
...  

Objectives: To determine the frequency of preterm labour in association with interpregnancy interval among pregnant women visiting tertiary care Hospital. Subject and Methods: This prospective cross-sectional study was performed at Unit-I, Obstetrics and Gynaecology Department, Civil Hospital Karachi; from June to November 2020. A total of 190 women with singleton pregnancy confirmed by ultrasound were included. After taking detailed medical history regarding previous fetal death and C-section was recorded either patient goes into preterm labour or not and confirmed by history for short and prolong interpregnancy interval (IPI). Data was collected by pre-designed study proforma. Results: The average age of study subjects was 26.27±4.07 years. The frequency of preterm labour among the pregnant women was 51.05%. The rate of preterm was significantly higher in those women who had with short inter interpregnancy interval (p=0.0005). Conclusion: Our findings clearly show that a short interval in inter-pregnancy is a cause of premature birth. Preterm birth can also be indicated by the antenatal care visits, inter-pregnancy complications, and having a birth defect. Premature birth minimization can enhance overall newborn's health and can lead to considerable minimization of neonatal death in the future. Keywords: Preterm labor, prolong pregnancy interval, neonatal health


2020 ◽  
Vol 7 (2) ◽  
pp. 80-83
Author(s):  
Shafeya Khanam ◽  
Nasrin Akhter ◽  
Muqsuda Ashraf Shuvro ◽  
Trifa Obayed ◽  
Habiba Shamim Sultana ◽  
...  

Background: Misoprostol is very useful for induction of labour among the pregnant women. Objective: The purpose of the present study was to see the indication and complication of induction of labour by misoprostol among pregnancy women. Methodology: This single center clinical trial was carried out in the Department of Obstetrics and Gynaecology at a private hospital in Dhaka city, Bangladesh from September 2005 to February 2006 for a period of six months. Primi or second gravida patients with the gestational age between 37 weeks to 42 weeks in singleton pregnancy with cephalic presentation and not in labour were selected as study population. After proper selection of the cases, induction of labour was done by applying tablet misoprostol 50mcg in the posterior vaginal fornix. Complication of induction were recorded. Result: A total number of 60 patients were recruited for this study. 24 patients were between 23 to 26 years and 12 patients were between 27 to 30 years. Pre-eclampsia, pregnancy induced hypertension and intrauterine growth retardation were the most common indication of induction. In this study 31(51.7%) patients needed only 1 dose of Misoprostol and 24 (40.0%) patients needed 2 doses and only 5(8.3%) patients needed 3 doses of Misoprostal. In this study 11.67% patients experienced Nausea & vomiting and 3.33% patients developed hyperstimulation. Conclusion: In the conclusion, the use of misoprostol results in a shorter induction to delivery time and miserable adverse effects on the method of delivery. Journal of Current and Advance Medical Research 2020;7(2): 80-83


Author(s):  
Asma Hassan Mufti ◽  
Samar Mukhtar ◽  
Mehmood-Ul-Hassan Mufti ◽  
Nasir Jeelani Wani

Background: To study clinical profile, maternal and fetal outcome in COVID positive pregnancies.Methods: A retrospective observational study was done at Lalla ded hospital, Kashmir, a tertiary care centre. 70 COVID positive pregnant women who were admitted from May 2020 to January 2021 were included in the study.Results: The incidence of COVID positive patients in our study was 11.47%. 60% of patients in our study belonged to 26-30 years age group. 50% patients were primigravida, 20% were second gravid. Among the study population, 31 (44.3%) patients were term while 22 (31.4%) were preterm. Most patients were asymptomatic (61.4%). Among symptomatic patients, maximum had fever (17.1%) followed by cough (10%) and shortness of breath (4.3%). Associated comorbidity was seen in 33 patients (47.1%). Hypertensive disorders of pregnancy were seen in majority i.e. 15.7%, followed by anaemia (11.4%), GDM (8.5%) and hypothyroidism (7.1%). Out of total study population of 70, emergency cesarean delivery (LSCS) was done in 29 patients (41.5%). 21 patients delivered vaginally (30%). Two post-LSCS patients were shifted to designated COVID Intensive care unit (ICU). One patient from the study group died. There were total of 50 deliveries, 10 babies had Neonatal ICU admission (20%), Low birth weight in 9 (18%). Low APGAR score was in 6 (12%). There were 2 stillbirths in the study population.Conclusions: COVID presents as milder disease in pregnancy, but it may be severe in those with associated comorbidities. More studies on susceptibility of pregnant women to infection by COVID-19 are required.


Author(s):  
Sandhya Choudhary ◽  
Swati .

Background: As HIV infection in women occurs primarily during reproductive years, hence incidence of HIV infection especially in sexually active women is more sensitive marker to track course of HIV epidemics. Pregnant women represent low risk population, so prevalence in pregnant women is proxy to HIV in general population.Methods: A prospective study was conducted in the Department of Obstetrics and Gynecology in JLN Medical College, Ajmer from April 2015 to August 2018. It included women attending antenatal clinic and emergency ward of labor room of our hospital.Results: Total 71 women were found positive for HIV out of 36,006 pregnant women who attended antenatal clinic, giving the prevalence of 0.197%. Out of these 71 cases, 1 case was positive for both HIV1 and HIV2. The prevalence of HIV positive women delivering in our hospital was 0.269%. 40.84% women belonged to age group 25-29.9 years and 39.43% to 19-24.9 years. Among 71 antenatal seropositive women, primigravida and second gravid accounted for equal fraction of the study population i.e. 33.80% each. 19.72% came from urban areas while 80.28% were from rural areas. 22.53% (16/71) had sero-discordant spouses. All seropositive women had singleton pregnancy and were housewives. 94.61% were registered for Anti-Retroviral Treatment (ART) and 5.39% went loss to follow up.Conclusions: The serodiscordance rate in our region is quite high (22.53%). Increased awareness in society leading to increase in number of pregnant women attending ICTC will help in reducing transmission of HIV by safer sex practices.


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