Analysis of the state of the autonomic nervous system, risk factors for the development of cardiovascular diseases in patients with chronic cerebral ischemia and chronic heart failure

Author(s):  
N. Zhhilova

This article describes the definition of the state of the autonomic nervous system in patients with chronic cerebral ischemia and chronic heart failure. It has been established that in patients with a reduced left ventricular ejection fraction was recorded the prevalence of the sympathetic link of the autonomic nervous system. Since the activation of the sympathetic nervous system is often a predictor of the development of diseases of the cardiovascular system, the detection of an increase in the activity of the sympathetic department of the autonomic nervous system in the early stages is one of the key moments in preventing the progression of diseases of the cardiovascular system.

Author(s):  
N. Zhhilova

The activation of the sympathetic nervous system plays an important pathophysiological role in the development of heart failure, in particular, in the development of left ventricular insufficiency. Although high blood pressure is considered as the main determinant of structural changes in the left ventricle, sex, salt intake, obesity, diabetes, as well as neurohumoral and genetic factors can affect the mass and left ventricular geometry. The usual concept of hypertonic re-modeling. In the comparative analysis of clinical and neurological manifestations in patients with chronic cerebral ischemia and chronic heart failure with a preserved and reduced release fraction, changes in the nervous system that showed a tendency to increase the disturbances and deviations from the norm with increasing heart failure, the fraction of release and the presence of hypertensive encephalopathy In the correlation analysis, a direct correlation between the quality of life indicator and the degree of heart failure (r = 0.56), the presence of myocardial infarction in the history (r = 0.42), arterial hypertension (r = 0.33) and the presence of valvular pathology the heart (r = 0.31) and the inverse correlation dependence on the indicator of the left ventricular ejection fraction (r = -0.69). A comparative analysis of correlation relationships indicates a reliable clinical and social significance of the left ventricular ejection fraction in patients with chronic cerebral ischemia and chronic heart failure.


2004 ◽  
Vol 93 (5) ◽  
pp. 650-654 ◽  
Author(s):  
Gianfranco Piccirillo ◽  
Quaglione Raffaele ◽  
Filippo Fimognari ◽  
Antonio Moisè ◽  
Malavasi Mario ◽  
...  

Author(s):  
N. Zhhilova

Chronic heart failure relates to the priorities of national health systems in most countries due to the high prevalence, steady increase in the number of new cases in all countries, frequent repeated hospitalizations, poor quality of treatment, high levels of disability and mortality, and increased treatment costs. An important multidisciplinary task is to study the state of the brain in the background of chronic cardiac pathology, which is associated with a violation of the pumping function of the heart and central hemodynamics. The purpose of the study was to investigate the state of the cognitive and psychoemotional sphere in patients with chronic cerebral ischemia and chronic heart failure with a preserved and reduced release fraction. In a comparative analysis in patients with chronic cerebral ischemia and chronic heart failure with a preserved and reduced emission fraction, a statistically significant difference was not found. Direct correlation dependence with complaints of memory impairment (r = 0.34), anxiety manifestations (r = 0.44), depression (r = 0.42). According to the study, cognitive impairment was observed in 95.3% of patients in group 1 and in 71.1% of patients in group 2. Dementia of light severity was found in patients with 1 group in 18.6% and in patients with 2 groups in 11.1%. Data from a neuropsychological study showed cognitive safety in 4.6% of patients in group I and 28.8% in group 2, which were characterized by mild modal-nonspecific mantle disorders. Premedicinal cognitive disorders were observed in group 1 in 33 (76.7%) patients and in 27 (60%) patients in group 2 (Table 1). There was a statistically significant difference between the groups p = 0.009 (p <0.05) and the direct correlation between MMSE and age (r = 0.63), quality of life (r = 0.31), complaints when considering deterioration of memory (r = 0.39).


2003 ◽  
Vol 146 (5) ◽  
pp. 854 ◽  
Author(s):  
Elisabetta De Tommasi ◽  
Massimo Iacoviello ◽  
Roberta Romito ◽  
Claudio Ceconi ◽  
Pietro Guida ◽  
...  

2018 ◽  
Vol 6 ◽  
pp. 55-60
Author(s):  
Nataliia Inhula

Aim. Practical cardiology is in constant search for non-invasive vascular risk markers. Heart rhythm reflects the body's response to various stimuli of the external and internal environment. Heart rate variability (HRV) has a prognostic and diagnostic value and allows timely identification of conditions that threaten life. The results of an instrumental examination of heart rhythm fluctuations in patients suffering from chronic cerebral ischemia against the background of angina pectoris of different functional classes allows to evaluate the prognosis of the disease and select the appropriate treatment. Materials and methods. An assessment of the state of the mechanisms of regulation of physiological functions in patients suffering from chronic cerebral ischemia against the background of angina pectoris of different functional classes was obtained according to spectral and temporal analysis of heart rate variability using electrocardiographic monitoring. The spectral characteristics of the heart rate variability were studied: HF (high frequency), LF (low frequency), VLF (very low frequency). Results. Heart rhythm regulation in patients with chronic cerebral ischemia occurred under the influence of neurohumoral mechanisms. The imbalance of functional systems was caused by changes in the autonomic nervous system, which disrupted the normal functioning of the sympathetic and parasympathetic parts. We marked decrease in the activity of the parasympathetic autonomic nervous system, which changed the indices of spectral analysis, while the high-frequency component of the spectrum was characterized by a decrease, while the low-frequency component was characterized by an increase. The progression of stable angina of tension (SAT) in patients with chronic cerebral ischemia (CCI) occurred with disruption of the autonomic nervous system (ANS) and was associated with a shift in the physiological response towards sympathetic activity. This was particularly pronounced in patients in group 2 with CCI on the background of SAT III FC, as the regulatory mechanisms were in a critical state of tension against the background of long-term chronic ischemia, they showed a high level of humoral modulation of regulatory mechanisms, which was manifested by excessive VLF and high-frequency oscillations. Conclusions. A connection was established between the autonomic nervous system and chronic cerebral ischemia, which was expressed in the imbalance of the ANS, associated with reliable signs of the dominant sympathetic system, which was associated with the progression of stable angina of tension.


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