scholarly journals Complicações renais decorrentes da infecção por SARS-CoV-2 em pessoas com COVID-19 hospitalizadas: scoping review

2022 ◽  
Vol 11 (1) ◽  
pp. e40811125217
Author(s):  
Anyele Albuquerque Lima ◽  
Alda Graciele Claudio dos Santo Almeida ◽  
Izabelly Carollynny Maciel Nunes ◽  
Patrícia de Albuquerque Sarmento ◽  
Wanda Tenório Barros Passos Alves

Objetivos: Identificar complicações/sequelas renais decorrentes da infecção por SARS-CoV-2 em pessoas com COVID-19; e descrever a característica de idade da população estudada. Metodologia: Scoping Review realizada nas bases de dados Web of Science, BVS, Cochrane Library, MEDLINE/PubMed, CINAHL, SCOPUS, Embase, LILACS. E nos sites online: ProQuest Dissertations and Theses, Grey Literature e Google Scholar. Os descritores utilizados foram (comorbidity OR sequel OR complications), (kidney diseases OR glomerular disease OR acute kidney injury OR nephropathy) AND (coronavirus OR SARS-CoV-2 OR COVID-19). Critérios de inclusão: artigos em português, inglês e espanhol, com abordagens metodológicas diversas, disponíveis na íntegra, online, publicados no período de 01 de janeiro de 2020 a 29 de setembro de 2021. E de exclusão: pessoas com diagnósticos prévios de patologias renais agudas e/ou crônicas; cartas ao editor; artigos de opinião; editoriais; e notas. Resultados: Selecionaram-se 10 artigos, que evidenciaram que o processo infeccioso causado pelo SARS-CoV-2 pode iniciar com uma leve proteinúria e hematúria, e evoluir para uma injúria renal aguda causada pela diminuição da capacidade de filtração glomerular, que favorece a retenção de algumas escórias nitrogenadas, causando o aumento dos níveis de creatinina e de ureia. Ademais, informaram que indivíduos entre 52-69 anos foram os mais acometidos. Considerações finais: As complicações/sequelas renais decorrentes da infecção por SARS-CoV-2 são: deposição de imunocomplexos nas células renais, proteinúria, hematúria, aumento da creatinina sérica, aumento da ureia nitrogenada no sangue, diminuição da TFG, e IRA estágio 1, 2 e 3. Tais complicações ocorreram principalmente em pessoas com idade ≥ 52 anos.

2021 ◽  
Author(s):  
Daniela Valdes ◽  
Lama Alqazlan ◽  
Rob Procter ◽  
Jeremy Dale

Abstract Background: Before the declaration of the COVID-19 pandemic in March 2020, primary care relied on face-to-face consultations, with relatively limited use of telemedicine. The rapid uptake that occurred following the onset of the pandemic in countries such as the United Kingdom, Canada and New Zealand prompts questions around the drivers and extent of this transformation in clinical practice at global level. The purpose of this scoping review is to explore the global evidence surrounding the rapid adoption of telemedicine in primary care settings during the first year of the COVID-19 pandemic. Methods: A draft protocol was tested through an initial search on Ovid Medline, Web of Science and Google Scholar with additional searches on the Cochrane Database. This informed the final selection of terms which will be use to search Ovid, Web of Science, Google Scholar, PROSPERO and Cochrane Library, filtering for studies from the pandemic declaration onwards. Additional grey literature reports will be sourced through simplified searches on appropriate search engines in widely spoken languages. Duplicates will be removed by screening titles. Abstracts and grey literature text extracts will be screened based on pre-set eligibility criteria by an automated tool and further screened by the lead researcher. Abstracts (and extracts in the case of grey literature) will be mapped against the domains of the Non-adoption, Abandonment, and challenges to Scale-up, Spread and Sustainability (NASSS) framework. Data will be presented in table format. Discussion: This review will map the current literature to identify current gaps in evidence related to the adoption of telemedicine after the declaration of the pandemic in March 2020. The use of simplified searches in the most spoken languages in the world is aimed at capturing more immediate non-academic reflections and experiences on this major service change at a global level.Systematic review registration: Study has been registered on Open Science Framework and can be accessed through the following URL: https://osf.io/4z5ut/


2021 ◽  
Vol 10 (16) ◽  
pp. e444101623459
Author(s):  
Fabiana Helena da Conceição ◽  
Viviani Aparecida Fraga ◽  
Cristiane Aparecida Silveira Monteiro ◽  
Melissa Santos Nassif ◽  
Isabelle Cristinne Pinto Costa

Objetivo: Este estudo tem como objetivo descrever o protocolo e a metodologia usados para realizar uma revisão de escopo que irá mapear as evidências científicas sobre a espiritualidade no contexto dos cuidados paliativos pediátricos. Metodologia: Trata-se de uma revisão de escopo que será desenvolvida conforme as recomendações do Instituto Joanna Briggs (JBI). Para a redação do estudo, será utilizado o PRISMA Extension for Scoping Reviews (PRISMA-ScR). Uma pesquisa abrangente será realizada nas bases de dados Web of Science, Scopus, Cochrane Library, PubMed, CINAHL e EMBASE, além da busca de literatura cinzenta nas bases Google Scholar, ProQuest e OpenGrey, sem limitação quanto ao ano de publicação e idioma. Além disso, será realizada busca adicional de artigos por meio da leitura das referências dos estudos incluídos na revisão. Serão incluídos estudos primários e secundários que abordem a espiritualidade no contexto dos cuidados paliativos pediátricos, independentemente do tipo de delineamento. Serão excluídos documentos do tipo cartas, comentários, editoriais e artigos de opinião. A seleção dos estudos por meio da leitura dos títulos, resumos e texto completo será conduzida por dois revisores independentes. A extração de dados será realizada por meio de formulário construído pelos autores com base nas recomendações do JBI. Os dados serão organizados, resumidos e analisados quanto à extensão, natureza, distribuição e padrões recorrentes e os resultados serão comunicados narrativamente e por meio de mapas de rede. Considerações finais: Espera-se que os resultados provenientes da realização desta revisão de escopo possam contribuir para o fortalecimento da utilização do cuidado espiritual às crianças sob os cuidados paliativos, com o escopo de promover uma melhor qualidade de vida para ela e seus familiares. Adicionalmente, pretende-se por meio dessa pesquisa estimular os profissionais de saúde a atender essa dimensão durante o cuidado à crianças sob os cuidados paliativos, com vistas a proporcionar um cuidado humanizado e uma assistência espiritual de qualidade que possam ajudá-los na busca de um significado para a vida, no alívio de dores e que facilitem a lidar com a angústia e o medo que permeiam esse processo.


Author(s):  
Sanjana Shirish Tipnis ◽  
Vaishnavi Vilas Pawar ◽  
Rahul Arun Shinde ◽  
Deeksha Kumari ◽  
Lavanya Padmashali ◽  
...  

Abstract Objective Successful community integration involves active participation in the community, broadly defined as having independence, relationships, and engagement in meaningful activities. This review aims to identify the literature focusing on community integration of individuals with stroke aged 18 years and older in the community over the past two decades. Methods This review will be based on the methodological framework given by Arksey and O’Malley (2005). We will include studies from SCOPUS, PubMed, Web of Science, Google Scholar, CINAHL, EBSCO, ClinicalKey, Wiley Online, ProQuest, and Cochrane Library databases published from January 2000 onwards. Both quantitative and qualitative data will be analyzed separately to identify various assessments, interventions, and factors that influence the community integration of individuals with stroke. Conclusion This scoping review will help to explore studies focusing on community integration among individuals with stroke aged 18 and older living in the community. It can further assist professionals who are addressing the concerns of individuals with stroke in the community.


Author(s):  
Zhixiang Mou ◽  
Xu Zhang

AbstractBackgroundCoronavirus disease 2019 (COVID-19) has spread rapidly worldwide and seriously threatens human health since December 2019. However, information about acute kidney injury (AKI) during COVID-19 infection is limited. Some studies thought that presence of AKI is very common and cannot be ignored, while some studies pointed that AKI only is a rare incident during COVID-19 infection. This meta-analysis aimed to find out the truth of COVID-19 related AKI and to provide stronger evidence.MethodsTwo authors independently performed a literature search using PubMed, Web of Science, Embase, and Cochrane Library fulfilled the pre-specified criteria until April 25, 2020 to include studies reported the necessary clinic characteristics, then the incidence of AKI, incidence of required RRT, the mortality with AKI and the death risk with AKI during COVID-19 infection were pooled for statistical analysis by Open Meta-Analyst software to get conclusions.FindingsIt was found that the incidence of AKI in hospitalized patients with COVID-19 infection is low, only about 3.8%; the in-hospital mortality with AKI in COVID-19 infected patients is reach up to 32.6%; the death risk with AKI in COVID-19 infected patients is about 16.1 times higher than those without AKI.ConclusionsThis meta-analysis indicated AKI during COVID-19 infection should be pay more attention, it maybe a strong red flag to death risk. It is still need additional studies to support the conclusions and to explore the AKI mechanism during COVID-19 infection.


2022 ◽  
Vol 11 (1) ◽  
pp. e12211124600
Author(s):  
Mylena de Souza Gomes ◽  
Marina das Dores Nogueira de Oliveira ◽  
Vânia Regina Bressan ◽  
Munyra Rocha Silva Assunção ◽  
Melissa Santos Nassif ◽  
...  

Objetivo: Descrever o protocolo e a metodologia usados para realizar uma revisão de escopo que irá mapear as evidências científicas sobre os referenciais teóricos utilizados na assistência de enfermagem no campo da saúde mental. Metodologia: Revisão de escopo desenvolvida conforme as recomendações do Instituto Joanna Briggs. Na redação do estudo, será utilizado o PRISMA Extension for Scoping Reviews. Uma pesquisa abrangente será realizada nos bancos e bases de dados MEDLINE/PubMed, Web of Science Core Collection/ Clarivate Analytics, Scopus, Cochrane Library, CINAHL, Biomedical Answers (EMBASE), LILACS/BVS, além da busca de literatura cinzenta nas bases Google Scholar, ProQuest e OpenGrey. Serão incluídos estudos primários e secundários que abordem as teorias de enfermagem no contexto da saúde mental e excluídos cartas, comentários, editoriais e artigos de opinião. Seleção dos estudos por meio da leitura dos títulos, resumos e texto completo conduzido por dois revisores independentes. Extração de dados realizada através de formulário construído com base nas recomendações do JBI. Os dados serão organizados, resumidos e analisados quanto à extensão, natureza, distribuição e padrões recorrentes, e os resultados serão comunicados narrativamente mediante mapas de rede. Considerações finais: Espera-se que estudo contribua para o fortalecimento da utilização de teorias de enfermagem na assistência em saúde mental, além de auxiliar os enfermeiros na prática, na pesquisa, na educação e na administração nas dimensões do cuidado.


Pain Medicine ◽  
2021 ◽  
Author(s):  
Daly Geagea ◽  
Zephanie Tyack ◽  
Roy Kimble ◽  
Lars Eriksson ◽  
Vince Polito ◽  
...  

Abstract Objective Inadequately treated pain and distress elicited by medical procedures can put children at higher risks of acute and chronic biopsychosocial sequelae. Children can benefit from hypnotherapy, a psychological tailored intervention, as an adjunct to pharmacological agents to address the multiple components of pain and distress. Despite providing evidence on the effectiveness and potential superiority of hypnotherapy to other psychological interventions, research on hypnotherapy for paediatric procedural pain and distress has been predominantly limited to oncology and needle procedures. Plus, there is a lack of reporting of intervention manuals, factors influencing hypnotic responding, pain unpleasantness outcomes, theoretical frameworks, adverse events, as well as barriers and facilitators to the feasibility of delivering the intervention and study procedures. The proposed review aims to map the range and nature of the evidence on hypnotherapy for procedural pain and distress in children to identify gaps in literature and areas requiring further investigation. Methods This review will follow the Arksey and O'Malley (2005) methodology and incorporate additional scoping review recommendations by The Joanna Briggs Institute and Preferred Reporting Items for Systematic reviews and Meta-Analyses. Relevant studies will be identified through searching published literature databases (PubMed, Cochrane Library, PsycINFO, Embase, CINAHL, Scopus and Web of Science) and grey literature in addition to hand-searching of reference lists and key journals. Two authors will independently screen titles and abstracts of search results followed by full-texts review against eligibility criteria. Conclusion Findings are anticipated to guide future research and inform the development of tailored hypnotic interventions in children.


2021 ◽  
Vol 10 (1) ◽  
Author(s):  
M. F. Van den Bosch ◽  
C. M. Wiepjes ◽  
M. Den Heijer ◽  
L. J. Schoonmade ◽  
R. E. G. Jonkman ◽  
...  

Abstract Background Gender-affirming hormone (GAH) therapy aims to support the transition of transgender people to their gender identity. GAHs can induce changes in their secondary sex characteristics such as the development of breasts in transgender females and increased muscle mass in transgender males. The face and its surrounding tissues also have an important role in gender confirmation. The aim of this scoping review is to systematically map the available evidence in order to provide an overview of the effects of GAH therapy on the hard and soft tissues of the craniofacial complex in transgender people. Methods/design The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA) extension for Scoping Reviews was consulted for reporting this protocol. The methods were based on the Arksey and O’Malley’s framework and the Reviewer’s Manual of the Joanna Briggs Institute for conducting scoping reviews. Ten transgender people were involved in the development of the primary research question through short interviews. The eligibility criteria were defined for transgender people undergoing GAH therapy and for quantitative and qualitative outcomes on the hard and soft tissues of the craniofacial complex. Eligible sources of evidence include observational, experimental, qualitative, and mixed method studies. No exclusion criteria will be applied for the language of publication and the setting. To identify eligible sources of evidence, we will conduct searches from inception onwards in PubMed, Embase.com, the Cochrane Library, Web of Science Core Collection, Scopus, CINAHL, LIVIVO, and various grey literature sources such as Google Scholar. Two reviewers will independently select eligible studies in these information sources and will subsequently conduct data extraction. The same operators will chart, categorize, and summarize the extracted data. A narrative summary of findings will be conducted. Frequency counts of quantitative and qualitative data on items such as concepts, populations, interventions, and other characteristics of the eligible sources will be given. Where possible, these items will be mapped descriptively. Discussion We chose the scoping review over the systematic review approach, because the research questions are broad-spectrum and the literature is expected to be widely scattered. No systematic review has previously assessed this topic. Identifying knowledge gaps in this area and summarizing and disseminating research findings are important for a wide spectrum of stakeholders, in particular, for transgender people who want to undergo additional interventions such as plastic or orthognathic surgery or orthodontics. Systematic review registration This protocol was registered in the Open Science Framework: https://osf.io/e3qj6


BMJ Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. e041894
Author(s):  
Joyce Kibaru ◽  
Pinky Kotecha ◽  
Abdulkarim Muhammad Iya ◽  
Beth Russell ◽  
Muzzammil Abdullahi ◽  
...  

IntroductionBladder cancer (BC) is the 10th common cancer worldwide and ranks seventh in Nigeria. This scoping review aims to identify the gaps in clinical care and research of BC in Nigeria as part of the development of a larger national research programme aiming to improve outcomes and care of BC.Methods and analysisThis review will be conducted according to Arksey and O’Malley scoping review methodology framework. The following electronic databases will be searched: Medline (using the PubMed interface), Ovid Gateway (Embase and Ovid), Cochrane library and Open Grey literature. Two independent reviewers will screen titles and abstracts and subsequently screen full-text studies for inclusion, any lack of consensus will be discussed with a third reviewer. Any study providing insight into the epidemiology or treatment pathway of BC (RCTs, observations, case series, policy paper) will be included. A data chart will be used to extract relevant data from the included studies. Results will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews. A consultation process will be carried out with a multidisciplinary team of Nigerian healthcare professionals, patients and scientists.Ethics and disseminationThe results will be disseminated through peer-reviewed publications. By highlighting the key gaps in the literature, this review can provide direction for future research and clinical guidelines in Nigeria (and other low-income and middle-income countries), where BC is more prevalent due to local risk factors and healthcare settings.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Katarzyna Szajek ◽  
Marie-Elisabeth Kajdi ◽  
Valerie A. Luyckx ◽  
Thomas Hans Fehr ◽  
Ariana Gaspert ◽  
...  

Abstract Background Acute kidney injury (AKI) associated with severe coronavirus disease 19 (COVID-19) is common and is a significant predictor of morbidity and mortality, especially when dialysis is required. Case reports and autopsy series have revealed that most patients with COVID-19 – associated acute kidney injury have evidence of acute tubular injury and necrosis - not unexpected in critically ill patients. Others have been found to have collapsing glomerulopathy, thrombotic microangiopathy and diverse underlying kidney diseases. A primary kidney pathology related to COVID-19 has not yet emerged. Thus far direct infection of the kidney, or its impact on clinical disease remains controversial. The management of AKI is currently supportive. Case Presentation The patient presented here was positive for SARS-CoV-2, had severe acute respiratory distress syndrome and multi-organ failure. Within days of admission to the intensive care unit he developed oliguric acute kidney failure requiring dialysis. Acute kidney injury developed in the setting of hemodynamic instability, sepsis and a maculopapular rash. Over the ensuing days the patient also developed transfusion-requiring severe hemolysis which was Coombs negative. Schistocytes were present on the peripheral smear. Given the broad differential diagnoses for acute kidney injury, a kidney biopsy was performed and revealed granulomatous tubulo-interstitial nephritis with some acute tubular injury. Based on the biopsy findings, a decision was taken to adjust medications and initiate corticosteroids for presumed medication-induced interstitial nephritis, hemolysis and maculo-papular rash. The kidney function and hemolysis improved over the subsequent days and the patient was discharged to a rehabilitation facility, no-longer required dialysis. Conclusions Acute kidney injury in patients with severe COVID-19 may have multiple causes. We present the first case of granulomatous interstitial nephritis in a patient with COVID-19. Drug-reactions may be more frequent than currently recognized in COVID-19 and are potentially reversible. The kidney biopsy findings in this case led to a change in therapy, which was associated with subsequent patient improvement. Kidney biopsy may therefore have significant value in pulling together a clinical diagnosis, and may impact outcome if a treatable cause is identified.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yasamin Veziari ◽  
Saravana Kumar ◽  
Matthew Leach

Abstract Background Over the past few decades, the popularity of complementary and alternative medicine (CAM) has grown considerably and along with it, scrutiny regarding its evidence base. While this is to be expected, and is in line with other health disciplines, research in CAM is confronted by numerous obstacles. This scoping review aims to identify and report the strategies implemented to address barriers to the conduct and application of research in CAM. Methods The scoping review was undertaken using the Arksey and O’Malley framework. The search was conducted using MEDLINE, EMBASE, EMCARE, ERIC, Scopus, Web of Science, The Cochrane Library, JBI and the grey literature. Two reviewers independently screened the records, following which data extraction was completed for the included studies. Descriptive synthesis was used to summarise the data. Results Of the 7945 records identified, 15 studies met the inclusion criteria. Using the oBSTACLES instrument as a framework, the included studies reported diverse strategies to address barriers to the conduct and application of research in CAM. All included studies reported the use of educational strategies and collaborative initiatives with CAM stakeholders, including targeted funding, to address a range of barriers. Conclusions While the importance of addressing barriers to the conduct and application of research in CAM has been recognised, to date, much of the focus has been limited to initiatives originating from a handful of jurisdictions, for a small group of CAM disciplines, and addressing few barriers. Myriad barriers continue to persist, which will require concerted effort and collaboration across a range of CAM stakeholders and across multiple sectors. Further research can contribute to the evidence base on how best to address these barriers to promote the conduct and application of research in CAM.


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