scholarly journals Bien estar de gallinas ponedoras y la osteoporosis

2020 ◽  
Vol 9 (3) ◽  
pp. e150932588
Author(s):  
Jose Evandro de Moraes ◽  
Mariana Rodrigues Borges ◽  
Lizandra Amoroso ◽  
Túlio Leite Reis ◽  
Ligia Fatima Lima Calixto ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Animal Welfare ◽  
Bone Tissue ◽  
Bone Mineralization ◽  
Natural Behavior ◽  
Mineral Bone Density

The objective of this review aspects concerned with the natural behavior of birds, the stress suffered when subjected to confinement, the importance of the study of the mineral bone density and the understanding of the causes of osteoporosis and appropriate measures to be taken to mitigate the severity of this disease and contribute to animal welfare. Therefore, the importance of research in the area of bone mineralization, adaptations to the environment and diets with adequate levels of calcium, vitamin D and phosphorus for maintenance of the quality of the bone tissue of birds is seen.

scholarly journals The influence of sports on indicators of mineral bone density among women descendants of migrants of KHMAO-Yugra

2016 ◽  
Vol 12 (1) ◽  
pp. 198-200
Author(s):  
Maxim V Stogov ◽  
Natalya V Chernitsyna ◽  
Roman V Kuchin
Keyword(s):  
Bone Density ◽  
Bone Mass ◽  
Bone Tissue ◽  
Preliminary Data ◽  
First Generation ◽  
Physical Culture ◽  
Mineral Density ◽  
Autonomous District ◽  
Middle Latitudes ◽  
Mineral Bone Density

The study shows that women descendants of migrants in the first generation, born and residing on the territory of KHMAO-Yugra, not engaged in physical culture and sports, according to densitometry mineral density of bone tissue shows signs of loss of bone mass, not observed in the residents of middle latitudes and the girls engaged in physical culture and sports, living in the Khanty-Mansiysk Autonomous district-Yugra. Preliminary data confirm the assumption that training in physical culture and sport contribute to the prevention of loss of bone mass in women living in the territory of KHMAO-Yugra.

Disorders of mineral bone density and vitamin D deficiency in chronic diseases of the gastrointestinal tract

2015 ◽  
Vol 21 (31) ◽  
pp. 28-32
Author(s):  
Тотров ◽  
Igor Totrov ◽  
Слохова ◽  
N. Slokhova ◽  
Медоева ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gastrointestinal Tract ◽  
Bone Density ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Chronic Diseases ◽  
Gastrointestinal Diseases ◽  
High Prevalence ◽  
Mineral Bone Density ◽  
Different Parts

This article presents the results of a study of mineral bone density, and vitamin D 25(OH)D3 in serum of 100 patients with chronic diseases of the stomach and duodenum. The results osteodensitometry studies have demonstrated a high prevalence of osteopenia and osteoporosis in different parts of the skeleton among the patients with diseases of the gastrointestinal tract. The decrease of vitamin D level in the blood serum of patients with diseases of the stomach and duodenum. The existing disorders of bone metabolism in patients with gastrointestinal diseases are connected with deficiency of vitamin D.

scholarly journals Premenopausal Osteoporosis & Perfluoroalkyl Substance Exposure; Is There a Link?

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A213-A213
Author(s):  
Bhavana Vemula ◽  
Omolola Bolaji Olajide
Keyword(s):  
Vitamin D ◽  
Lumbar Spine ◽  
Bone Density ◽  
Bone Mineralization ◽  
Consumer Products ◽  
Low Bone Density ◽  
Lower Lumbar Spine ◽  
Wide Range ◽  
Premenopausal Osteoporosis ◽  
History Of

Abstract Introduction: Perfluoroalkyl substances (PFAS) like Perflouroctanoate (PFOA) and Perflurooctane sulfonate (PFOS) are ubiquitous environmental contaminants that have been in industrial use for many years. Many known adverse effects include malignancies, reproductive and thyroid dysfunction. However, there is limited literature regarding PFAS causing low bone density. We report a case of a premenopausal woman with a history of exposure to PFAS who was recently diagnosed with osteoporosis. Clinical Case: A 36-year-old lady with a history of hypothyroidism, on levothyroxine, presented to the orthopedics clinic with complaints of sudden onset right foot pain with no trauma. She was found to have a fracture of her right second metatarsal bone. Notably, over a period of five years she had suffered multiple fractures including metatarsal, elbow and a wrist fracture, all with minimal or no trauma. She denied smoking, alcohol, chronic steroid or PPI use, history of malabsorption, celiac disease, kidney stones, malignancy or liver problems. Her menstrual cycles were regular; she was on oral contraceptives in the past for dysmenorrhea. She is on Vitamin D supplementation and consumes adequate dairy products daily. There is no family history of hip fracture or osteoporosis. Labs showed: Calcium 8.9mg/dl, Phosphorus 2.4mg/dl (2.5–4.5mg/dl), intact PTH was 92.7pg/ml (8-97pg/ml), 24-hour urine calcium was undetectable. Vitamin D was 56.6ng/ml (30-100ng/ml). CBC, TSH, FSH, liver & kidney functions were all normal. Anti-endomysial, anti-gliadin and anti-tissue trans glutaminase antibodies were all unremarkable. IgA level was 362mg/dl (8–352 mg/dl). DXA scan revealed the lowest Z-score (-3.1) in the lumbar spine. She reported a history of exposure to PFAS with a blood level of 22.3ng/ml for PFOA and 48.4ng/ml for PFOS in the year 2005. Plan is to initiate bisphosphonate therapy for the treatment of osteoporosis. Discussion: PFAS are known endocrine disruptive agents that have been used widely in making a wide range of consumer products including nonstick and stain-resistant coatings of cookware, food containers. Recent studies suggest that serum PFAS concentrations were associated with lower bone density. There was a higher incidence of lower lumbar spine bone density in patients exposed to PFOS. PFOA is believed to compete with calcitriol at the same binding site on Vitamin D receptor resulting in changes in the osteoblasts thereby decreasing bone mineralization. Conclusion: There needs to be increased awareness about the association of low bone density in patients exposed to PFAS. This is especially important in the evaluation of premenopausal osteoporosis. References: 1. Environ Health Perspect. 2016 Jan;124 (1):81–7, 2. J Clin Endocrinol Metab 2014; 99(6) 2173–2180, 3. Sci Rep 2020 Oct 8;1091):16789

Use of Alendronate in Postoperative Period for Prevention of Hip Implant Aseptic Instability

2009 ◽  
Vol 16 (3) ◽  
pp. 36-44
Author(s):  
Svetlana Semenovna Rodionova ◽  
T N Turgumbaev ◽  
S S Rodionova ◽  
T N Turgumbaev
Keyword(s):  
Calcium Carbonate ◽  
Bone Density ◽  
Bone Tissue ◽  
Postoperative Period ◽  
Main Group ◽  
Control Group ◽  
Study Group ◽  
Surgical Team ◽  
Tissue Mass ◽  
Mineral Bone Density

Assessment of the alendronate influence upon the course of adaptive remodeling of bone tissue adjacent to the implant was performed. Dynamics of mineral bone density (BMD) changes in Gruen zones was compared for 2 groups of female patients. The groups were similar by age, nosology. All operations were performed by the same surgical team with application of one type of implant (Zweymuller). During the first post-operative year patients from the study group (n=38) were taken alendronate (Fosamax-70) once a week and at least 1200 mg of calcium carbonate daily (either as calcium containing food products or calcium carbonate preparations). Patients from control group (n=94) were taken only calcium carbonate by the same scheme within the first postoperative year. It was detected that although by 6th postoperative month alendronate did not decraese BMD loss as compared to controls, within the interval of 6-15 months it significantly increased bone tissue mass accretion. In group of alendronate patients monthly accretion of bone tissue in some Gruen zones (except for R4) was twice and more higher than in control group. Fifteen months later patients from the main group showed BMD deficit only in R4 zone. In the rest of zones bone tissue mass exceeded the basic values and in the majority of zones that increase was trustworthy. In control group BMD deficit was preserved in two proximal zones (R6 and R7) and in zone R6 it even increased as compared to the results of the previous study (12 months after operation).

scholarly journals THE INFLUENCE OF EXOCRINE PANCREATIC INSUFFICIENCY IN THE FORMATION OF OSTEOPENIA IN PATIENTS WITH PRIMARY OSTEOARTHRITIS

2020 ◽  
Vol 73 (10) ◽  
pp. 2238-2240
Author(s):  
Liliya S. Babinets ◽  
Iryna M. Halabitska ◽  
Iryna O. Borovyk ◽  
Olena V. Redkva ◽  
Halyna M. Sasyk
Keyword(s):  
Bone Density ◽  
Bone Tissue ◽  
Pancreatic Insufficiency ◽  
Elisa Test ◽  
Exocrine Pancreatic Insufficiency ◽  
Mineral Density ◽  
X Ray ◽  
Primary Osteoarthritis ◽  
Mineral Bone Density ◽  
Mineral Changes

The aim: Make complex study of bone density in patients with primary osteoarthritis and exocrine pancreatic insufficiency and patients with primary osteoarthritis without exocrine pancreatic insufficiency. Materials and methods: There were examined 140 patients with primary osteoarthritis without exocrine pancreatic insufficiency and combination osteoarthritis and exocrine pancreatic insufficiency. Diagnosis of osteoarthritis was based on diagnostic X-Ray criteria – according to J.H. Kellgren and J.S. Lawrence. The level of exocrine pancreatic insufficiency was based on result of Elisa test. State of mineral bone density was examined by using dual-photon densitometry. Results: It was established that there was a progressive, statistical, significant increase of mineral density of bone tissue in the 1-st group patients with osteoarthritis. Patients in the 2-nd group, with osteoarthritis in the comorbidity with exocrine pancreatic insufficiency, the densitogram rates were statistically significantly lower than in patients in the 1-st group. Conclusions: The changes of bone tissue can be explained by the formation of trophological insufficiency as a result of exocrine pancreatic insufficiency. One of the symptoms of trophic failure is bone and mineral changes, in particular, the decrease of bone density.

Analysis of vitamin D receptor polymorphism and its relation to mineral bone density in the pathogenesis of osteoporosis

2015 ◽  
Vol 67 ◽  
pp. 19-20
Author(s):  
Bogusław Czerny ◽  
Dariusz Boroń ◽  
Anna Bogacz ◽  
Karolina Dziekan ◽  
Aleksandra Kowalska ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Vitamin D Receptor ◽  
Vitamin D Receptor Polymorphism ◽  
Mineral Bone Density ◽  
Receptor Polymorphism

scholarly journals SURGICAL TREATMENT OF VERTEBRAL FRACTURES ASSOCIATED WITH LOW MINERAL BONE DENSITY

2010 ◽  
Vol 16 (2) ◽  
pp. 116-119
Author(s):  
V. V. Rerikh ◽  
M. A. Sadovoy ◽  
Sh. N. Rakhmatillaev ◽  
K. Q. Borzykh
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Bone Density ◽  
Internal Fixation ◽  
Clinical Outcomes ◽  
Vertebral Fractures ◽  
Transpedicular Fixation ◽  
Vertebral Bodies ◽  
Mineral Bone Density

Surgical treatment of 177 patients with monolocal fractures of thoracic and lumbar vertebral bodies was performed using transpedicular fixation (n=17), transpedicular fixation and osteoplasty (n=101), vertebroplasty (n=48) or kyphoplasty (n=ll). Restoration of support ability of the fractured osteoporotic vertebrae within ventral column by means of plasty particularly in combination with internal fixation allows achievement of better clinical outcomes, improvement of the quality of life in patients in the early and late periods after surgery.

Insufficiency of vitamin D in Madrid’s postmenopausal women: influence of vitamin D on mineral bone density

Bone ◽  
2001 ◽  
Vol 29 (3) ◽  
pp. 309-310
Author(s):  
M.L González Casaús ◽  
P Aguado ◽  
M.T Del Campo ◽  
M.V Garcés ◽  
M Bernad ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Postmenopausal Women ◽  
Mineral Bone Density

scholarly journals Eldecalcitol is more effective for promoting osteogenesis than alfacalcidol in Cyp27b1-knockout Mice

2018 ◽  
Author(s):  
Yoshihisa Hirota ◽  
Kimie Nakagawa ◽  
Keigo Isomoto ◽  
Toshiyuki Sakaki ◽  
Noboru Kubodera ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Postmenopausal Osteoporosis ◽  
Cancellous Bone ◽  
Knockout Mice ◽  
Bone Mineralization ◽  
Active Vitamin ◽  
Mineral Density ◽  
Active Vitamin D ◽  
Calbindin D

AbstractCalcium (Ca) absorption from the intestinal tract is promoted by active vitamin D (1α,25D3). Vitamin D not only promotes Ca homeostasis, but it also inhibits bone resorption and promotes osteogenesis, thus playing a role in the maintenance of normal bone metabolism. Because 1α,25D3 plays an important role in osteogenesis, vitamin D formulations, such as alfacalcidol (ALF) and eldecalcitol (ELD), are used for treating osteoporosis. While it is known that, in contrast to ALF, ELD is an active ligand that directly acts on bone, the reason for its superior osteogenesis effects is unknown. Cyp27b1-knockout mice (Cyp27b1−/− mice) are congenitally deficient in 1α,25D3 and exhibit marked hypocalcemia and high parathyroid hormone levels, resulting in osteodystrophy involving bone hypocalcification and growth plate cartilage hypertrophy. However, because the vitamin D receptor is expressed normally in Cyp27b1−/− mice, they respond normally to 1α,25D3. Accordingly, in Cyp27b1−/− mice, the pharmacological effects of exogenously administered active vitamin D derivatives can be analyzed without being affected by 1α,25D3. We used Cyp27b1−/− mice to characterize and clarify the superior osteogenic effects of ELD on the bone in comparison with ALF. The results indicated that compared to ALF, ELD strongly induces ECaC2, calbindin-D9k, and CYP24A1 in the duodenum, promoting Ca absorption and decreasing the plasma concentration of 1α,25D3, resulting in improved osteogenesis. Because bone morphological measurements demonstrated that ELD has stronger effects on bone calcification, trabecular formation, and cancellous bone density than ALF, ELD appears to be a more effective therapeutic agent for treating postmenopausal osteoporosis, in which cancellous bone density decreases markedly. By using Cyp27b1−/− mice, this study was the first to succeed in clarifying the osteogenic effect of ELD without any influence of endogenous 1α,25D3. Furthermore, ELD more strongly enhanced bone mineralization, trabecular proliferation, and cancellous bone density than did ALF. Thus, ELD is expected to show an effect on postmenopausal osteoporosis, in which cancellous bone mineral density decreases markedly.

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