scholarly journals The Evolution of Taste and Perinatal Programming of Taste Preferences

2018 ◽  
pp. S421-S429 ◽  
Author(s):  
Š. PODZIMEK ◽  
M. DUŠKOVÁ ◽  
Z. BROUKAL ◽  
B. RÁCZ ◽  
L. STÁRKA ◽  
...  
Keyword(s):  
Early Childhood ◽  
Sweet Taste ◽  
Sensitive Period ◽  
Published Data ◽  
Taste Preferences ◽  
Taste Receptors ◽  
Flavor Preference ◽  
Perinatal Programming ◽  
Increased Risk ◽  
Early Human

Taste is important for food intake. The fetus first experiences taste through amniotic fluid, and later via mother’s milk. Early human experience with taste has a key importance for later acceptance of food. Dietary behavior is determined by the interaction of many different factors. The development of the olfactory and taste receptors begins at 7-8 weeks of gestation. An early sensitive period probably exists when flavor preference is established. Sweet taste is preferred in early childhood; this is the reason why children are at increased risk of over-consuming saccharides. Gustatory sensitivity declines with age. The threshold for the perception of each basic taste differs, and is established genetically. In this review, we summarize published data on taste preferences and its development and changes during life.

scholarly journals Taste receptors are our mediators in shaping the taste preferences of a child

2018 ◽  
pp. 50-55
Author(s):  
I. N. Zakharova ◽  
A. N. Kasyanova ◽  
Yu. А. Dmitrieva ◽  
Е. B. Machneva
Keyword(s):  
Genetic Factors ◽  
Sweet Taste ◽  
Practical Significance ◽  
Cellular Structures ◽  
Taste Preferences ◽  
Taste Receptors ◽  
Genetic Determinants ◽  
Umami Taste ◽  
Sweet Taste Receptors

The article presents modern data on the main molecular and genetic determinants of shaping the taste preferences. The authors present the structure and mechanism of the functioning of sweet taste receptors, umami taste, acidic and bitter tastes, as well as other molecules and cellular structures influencing the perception of flavors – the gust protein, toll-like receptors. They described the role of structures ensuring perception of taste outside the oral cavity – the cells of the hypothalamus. The article underlines the importance of the genetic polymorphism of these structures and the importance of interaction of genetic factors and environmental factors in shaping the taste preferences and eating behavior of the infant. Particular attention is given to the practical significance of the presented data in the context of introduction of supplemental foods for infants.

scholarly journals Taste sensations: history of study, evolutionary feasibility and strategies for forming correct taste preferences in children

2020 ◽  
pp. 65-73
Author(s):  
I. N. Zakharova ◽  
Yu. A. Dmitrieva ◽  
E. B. Machneva ◽  
A. N. Tsutsaeva
Keyword(s):  
Eating Disorders ◽  
Human Health ◽  
Taste Receptor ◽  
Sweet Taste ◽  
Food Selectivity ◽  
Taste Preferences ◽  
Taste Receptors ◽  
Sweet Taste Receptor ◽  
Sweet Taste Receptors ◽  
History Of

Taste preferences influence not only the formation of human health, but also many areas of his life. That is why the problem of understanding the nature and regularities of taste formation has been a concern for scientists since ancient times and remains relevant nowadays. The article presents generalized data on the history of studying taste from the times of Ancient Greece to our time. Notions about the system of taste sensations in works of Aristotle, Galen, Avicenna, Vesaliy, other medieval scientists and researchers of New time are described. The authors also present an overview of current studies on the evolutionary appropriateness of taste sensations using the expression of sweet taste receptors in animals with different diets. It has been shown that obligate carnivorous animals have lost the function of sweet taste receptors, and in hummingbirds eating sweet floral nectar, on the contrary, another sweet taste receptor has acquired the function of a sweet taste receptor to detect sugars. The authors pay special attention to the available ways of forming correct taste preferences and overcoming eating disorders in infants, which is important from the point of view of the child’s future health. In particular, strategies for repeated taste effects of new foods as well as multisensory interactions with food, including sound, visual, olfactory, tactile and tasting effects are presented. It is particularly important to develop correct taste habits in children with eating disorders such as neophobia and food selectivity. Understanding the multifactorial nature of taste preferences and their impact on human health allows finding new strategies to «teach» taste from early childhood.

495-P: Kidney May Regulate SGLT2-Dependent Glucose Reabsorption through Sweet Taste Receptors: Implications for Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 495-P
Author(s):  
LUPING ZHOU ◽  
WEI HUANG ◽  
NAN LIU ◽  
XIU M. MA ◽  
MAN GUO ◽  
...  
Keyword(s):  
Sweet Taste ◽  
Taste Receptors ◽  
Glucose Reabsorption ◽  
Sweet Taste Receptors

scholarly journals Differences in Sweet Taste Perception and Its Association with the Streptococcus mutans Cariogenic Profile in Preschool Children with Caries

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2592
Author(s):  
Anna Jurczak ◽  
Małgorzata Jamka-Kasprzyk ◽  
Zuzanna Bębenek ◽  
Małgorzata Staszczyk ◽  
Paweł Jagielski ◽  
...  
Keyword(s):  
Preschool Children ◽  
Sweet Taste ◽  
Assessment System ◽  
Taste Perception ◽  
Taste Preferences ◽  
Microbiological Analysis ◽  
Strong Positive Correlation ◽  
Chi Square ◽  
Icdas Ii ◽  
Chi Square Test

The aim of the study was to verify the hypothesis about differences in sweet taste perception in the group of preschool children with and without caries, and to determine its relationship with cariogenic microbiota and the frequency of sweets consumption in children. The study group included of 63 children aged 2–6 years: 32 with caries and 31 without caries. The study consisted of collecting questionnaire data and assessment of dental status using the decayed, missing, filled in primary teeth index (dmft) and the International Caries Detection and Assessment System (ICDAS II). The evaluation of sweet taste perception was carried out using a specific method that simultaneously assessed the level of taste preferences and the sensitivity threshold for a given taste. The microbiological analysis consisted of the assessment of the quantitative and qualitative compositions of the oral microbiota of the examined children. The sweet taste perception of children with caries was characterized by a lower susceptibility to sucrose (the preferred sucrose solution concentration was >4 g/L) compared to children without caries (in the range ≤ 4 g/L, p = 0.0015, chi-square test). A similar relationship was also observed for frequent snacking between meals (p = 0.0038, chi-square test). The analysis of studied variables showed the existence of a strong positive correlation between the perception of sweet taste and the occurrence and intensity of the cariogenic process (p = 0.007 for dmft; and p = 0.012 for ICDAS II), as well as the frequency of consuming sweets (p ≤ 0.001 for frequent and repeated consumption of sweets during the day, Spearman test) in children with caries. Additionally, children with an elevated sucrose taste threshold were more than 10-times more likely to develop S. mutans presence (OR = 10.21; 95% CI 3.11–33.44). The results of this study suggest the future use of taste preferences in children as a diagnostic tool for the early detection of increased susceptibility to caries through microbial dysbiosis towards specific species of microorganisms.

scholarly journals Long term alterations of growth after antenatal steroids in preterm twin pregnancies

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Thorsten Braun ◽  
Vivien Filleböck ◽  
Boris Metze ◽  
Christoph Bührer ◽  
Andreas Plagemann ◽  
...  
Keyword(s):  
Early Childhood ◽  
Disease Risk ◽  
Later Life ◽  
Ponderal Index ◽  
Childhood Growth ◽  
Antenatal Steroids ◽  
Increased Risk ◽  
Infancy And Early Childhood ◽  
Twin Pregnancies

AbstractObjectivesTo compare the long-term effects of antenatal betamethasone (ANS, ≤16 mg, =24 mg and >24 mg) in twins on infant and childhood growth.MethodsA retrospective cohort follow up study among 198 twins after ANS including three time points: U1 first neonatal examination after birth and in the neonatal period; U7 examination from the 21st to the 24th month of life and U9 examination from the 60th to the 64th month of life using data from copies of the children’s examination booklets. Inclusion criteria are twin pregnancies with preterm labor, cervical shortening, preterm premature rupture of membranes, or vaginal bleeding, and exposure to ANS between 23+5 and 33+6 weeks. Outcome measures are dosage-dependent and sex-specific effects of ANS on growth (body weight, body length, head circumference, body mass index and ponderal index) up to 5.3 years.ResultsOverall, 99 live-born twin pairs were included. Negative effects of ANS on fetal growth persisted beyond birth, altered infant and childhood growth, independent of possible confounding factors. Overall weight percentile significantly decreased between infancy and early childhood by 18.8%. Birth weight percentiles significantly changed in a dose dependent and sex specific manner, most obviously in female-female and mixed pairs. The ponderal index significantly decreased up to 42.9%, BMI index increased by up to 33.8%.ConclusionsANS results in long-term alterations in infant and childhood growth. Changes between infancy and early childhood in ponderal mass index and BMI, independent of dose or twin pair structure, might indicate an ANS associated increased risk for later life disease.SynopsisFirst-time report on long-term ANS administration growth effects in twin pregnancies, showing persisting alterations beyond birth in infant and childhood growth up to 5.3 years as potential indicator of later life disease risk.

Upgrade rates and outcomes of screen-detected atypical intraductal epithelial proliferation (AIDEP) diagnosed on core needle biopsy

2021 ◽  
pp. 1-6
Author(s):  
Emma C. Dunne ◽  
Edel M. Quinn ◽  
Maurice Stokes ◽  
John M. Barry ◽  
Malcolm Kell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Demographic Data ◽  
Screening Mammography ◽  
Published Data ◽  
Epithelial Proliferation ◽  
Core Needle ◽  
In Situ Carcinoma ◽  
Increased Risk

INTRODUCTION: Atypical intraductal epithelial proliferation (AIDEP) is a breast lesion categorised as “indeterminate” if identified on core needle biopsy (CNB). The rate at which these lesions are upgraded following diagnostic excision varies in the literature. Women diagnosed with AIDEP are thought to be at increased risk of breast cancer. Our aim was to identify the rate of upgrade to invasive or in situ carcinoma in a group of patients diagnosed with AIDEP on screening mammography and to quantify their risk of subsequent breast cancer. METHODS: We conducted a retrospective review of a prospectively maintained database containing all patients diagnosed with AIDEP on CNB between 2005 and 2012 in an Irish breast screening centre. Basic demographic data was collected along with details of the original CNB result, rate of upgrade to carcinoma and details of any subsequent cancer diagnoses. RESULTS: In total 113 patients were diagnosed with AIDEP on CNB during the study period. The upgrade rate on diagnostic excision was 28.3% (n = 32). 6.2% (n = 7) were upgraded to invasive cancer and 22.1% (n = 25) to DCIS. 81 patients were not upgraded on diagnostic excision and were offered 5 years of annual mammographic surveillance. 9.88% (8/81) of these patients went on to receive a subsequent diagnosis of malignancy. The mean time to diagnosis of these subsequent cancers was 65.41 months (range 20.18–145.21). CONCLUSION: Our data showing an upgrade rate of 28% to carcinoma reflects recently published data and we believe it supports the continued practice of excising AIDEP to exclude co-existing carcinoma.

scholarly journals Lack of functionally active sweet taste receptors in the jejunum in vivo in the rat

2013 ◽  
Vol 183 (2) ◽  
pp. 606-611 ◽  
Author(s):  
Rizwan M. Chaudhry ◽  
Alok Garg ◽  
Mohamed M. Abdelfatah ◽  
Judith A. Duenes ◽  
Michael G. Sarr
Keyword(s):  
Sweet Taste ◽  
Taste Receptors ◽  
Sweet Taste Receptors
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