Optimization of treatment of recurrent vulvovaginal candidiasis

The purpose of the study was to evaluate the efficacy of treatment of recurrent drug Orungamin depending on the time of occurrence of relapse.Material and methods. 62 women with recurrent candida vulvovaginit is were examined and treated. The mean age of the patients was 35.6 ± 0.7 years. The main group consisted of 32 patients who in the premenstrual period 5 days before the expected date of menstruation were prescribed Orungamin 1 capsule (100 mg) twice a day (200 mg) for 3 days during three consecutive menstrual cycles. The comparison group included women receiving Orungamin three consecutive cycle 3 day 1 capsule (100 mg) 2 times a day, without regard to days of the menstrual cycle.Results. Therapy with Orungamin 100 mg twice a day during the premenstrual period not only helped to increase the effectiveness of the treatment of relapses, but also the quality of life of patients.

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Recurrent Vulvovaginal Candidiasis

BioScientia Medicina ◽

10.32539/bsm.v5i5.280 ◽

2021 ◽

Vol 5 (5) ◽

pp. 474-483

Author(s):

Cyntya Sari Sovianti ◽

Mutia Devi

Keyword(s):

Quality Of Life ◽

Topical Therapy ◽

Predisposing Factors ◽

Vulvovaginal Candidiasis ◽

Suppressive Therapy ◽

Recurrent Vulvovaginal Candidiasis ◽

Candida Sp ◽

Microbiological Examination ◽

Culture Negative

Vulvovaginal candidiasis is a common fungal infection caused by Candida Sp, especially Candida albicans. Recurrent vulvovaginal candidiasis was defined as the occurrence of four or more episodes of vulvovaginal candidiasis in 12 months period. As many as 9% of women from various populations have recurrent vulvovaginal candidiasis. Vulvovaginal candidiasis affects the quality of life, mental health, and sexual activity. There are many predisposing factors that caused recurrent vulvovaginal candidiasis, such as genetics, host, habit, idiopathic and non-albican candida microbes. Management of recurrent vulvovaginal candidiasis includes elimination of predisposing factors; mycological culture diagnosis and identification of specific Candida species; followed by microbiological examination to confirm the sensitivity of the azole group to Candida sp. Further, oral, or topical therapy should be continued until the patient is asymptomatic and culture-negative. Patients should receive induction therapy followed by maintenance suppressive therapy for six months.

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Recurrent Vulvovaginal Candidiasis

BioScientia Medicina ◽

10.32539/bsm.v5i3.280 ◽

2021 ◽

Vol 5 (3) ◽

pp. 498-507

Author(s):

Cyntya Sari Sovianti ◽

Mutia Devi

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Topical Therapy ◽

Predisposing Factors ◽

Vulvovaginal Candidiasis ◽

Suppressive Therapy ◽

Recurrent Vulvovaginal Candidiasis ◽

Candida Sp ◽

Culture Negative

Vulvovaginal candidiasis is a common fungal infection caused by Candida Sp,especially Candida albicans. Recurrent vulvovaginal candidiasis was defined asthe occurrence of four or more episodes of vulvovaginal candidiasis in 12 monthsperiod. As many as 9% of women from various populations have recurrentvulvovaginal candidiasis. Vulvovaginal candidiasis affects the quality of life,mental health, and sexual activity. There are many predisposing factors thatcaused recurrent vulvovaginal candidiasis, such as genetics, host, habit,idiopathic and non-albican candida microbes. Management of recurrentvulvovaginal candidiasis includes elimination of predisposing factors; mycologicalculture diagnosis and identification of specific Candida species; followed bymicrobiological examination to confirm the sensitivity of the azole group toCandida sp. Further, oral, or topical therapy should be continued until the patientis asymptomatic and culture-negative. Patients should receive induction therapyfollowed by maintenance suppressive therapy for six months.

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Internet-based cognitive-behavioral therapy for premenstrual syndrome: a randomized controlled trial

BMC Women s Health ◽

10.1186/s12905-021-01589-7 ◽

2022 ◽

Vol 22 (1) ◽

Author(s):

Sanam Borji-Navan ◽

Sakineh Mohammad-Alizadeh-Charandabi ◽

Khalil Esmaeilpour ◽

Mojgan Mirghafourvand ◽

Ali Ahmadian-Khooinarood

Keyword(s):

Quality Of Life ◽

Menstrual Cycle ◽

Cognitive Behavioral Therapy ◽

Premenstrual Syndrome ◽

Symptom Severity ◽

Behavioral Therapy ◽

Intervention Group ◽

Control Group ◽

Menstrual Cycles

Abstract Background Premenstrual syndrome (PMS) is a common problem of women of reproductive age, affecting various aspects of their lives. However, limited studies have investigated the effect of internet-based cognitive-behavioral therapy (ICBT) on PMS. Therefore, we aimed to assess whether ICBT can reduce symptom severity of women with PMS and improve their quality of life during the perimenstrual and late follicular phases of menstrual cycle. Methods The study included 92 university students aged 18–35 years who had moderate to severe PMS. The participants were allocated into two groups of 46 using block randomization. The intervention group underwent ICBT for two menstrual cycles, while the control group received no intervention. Before and after the intervention, all participants filled the Daily Record of Severity of Problems (DRSP) for two menstrual cycles and the Quality of Life Enjoyment and Satisfaction Questionnaire—Short Form (Q-LES-Q-SF) on days 1–2 and 11–13 of the menstrual cycle. Data were analyzed using univariate general linear models. Results Four students in the intervention group were lost to follow-up. Following the intervention, the mean score of total PMS symptoms was significantly lower in the intervention group than in the control group (10.4 vs. 20.2, adjusted difference: − 9.9 [95% CI − 13.3 to − 6.6]), and the score of perimenstrual quality of life was significantly higher (64.2 vs. 50.3, 14.1 [8.5 to 19.8]). However, there was no significant intergroup difference in the late follicular quality of life (68.3 vs. 67.3, 1.9 [− 4.4 to 8.1]). Conclusions The ICBT could reduce the symptom severity of women suffering from PMS while improving their perimenstrual quality of life. However, it had no significant effect on the late follicular quality of life. Therefore, this intervention can be used for women with PMS. Trial registration The Iranian Registry of Clinical Trials, Identifier: IRCT20100414003706N34, Registered prospectively on 19 June 2019, https://www.irct.ir/trial/38394.

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Influence of recurrent vulvovaginal candidiasis on quality of life issues

Archives of Gynecology and Obstetrics ◽

10.1007/s00404-019-05228-3 ◽

2019 ◽

Vol 300 (3) ◽

pp. 647-650 ◽

Cited By ~ 4

Author(s):

Eiko I. Fukazawa ◽

Steven S. Witkin ◽

Renata Robial ◽

João G. Vinagre ◽

Edmund C. Baracat ◽

...

Keyword(s):

Quality Of Life ◽

Vulvovaginal Candidiasis ◽

Recurrent Vulvovaginal Candidiasis ◽

Life Issues

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Treatment of Dysmenorrhea with Physiological Modulators (A28): A Registry Study

10.53902/pwhcij.2021.01.000501 ◽

2020 ◽

Vol 1 (1) ◽

Author(s):

Cornelli U

Keyword(s):

Quality Of Life ◽

Vitamin D ◽

Side Effects ◽

Registry Study ◽

Calcium Salts ◽

Menstrual Cycles ◽

Before And After ◽

Menstruating Women ◽

The Mean

Background: Dysmenorrhea is a diseases affecting about 45% of menstruating women (approximately between 45 to 95 % of females) during the time of menses and causing a reduction of the quality of life. Objective: To reduce the symptoms of dysmenorrhea using a natural Physiological Mosdulator (A 28) consisting of low dosages of calcium salts, Vitamin D, bioflavonoids, lycopene, and astaxanthin. Material and methods: Forty patients with severe dysmenorrhea were analyzed during two menstrual cycles: the first as baseline following a run-inn period, and the second during the treatment with A28. A simple VAS scale scoring the daily discomfort (from 0 =no discomfort to 6 =maximum discomfort) was used to measure the severity of the symptoms.The total score of first 3 days following the start of menses was calculated.The use of pain rescue cps during the two period was compared. Results: Thirty-eight cases completed the experience. Before treatment, the mean of total scores was 8.1±2.40, while after A28 it was reduced to 1.7± 1.39 (U Mann Whitney p< 0.01) . The mean of pain rescue cps used was respectively 6.1±1.21 and 0.5±1.15 before and after the A28 treatment (p <0.01). No side effects were reported. Conclusion: The use ofa combination of Physiological Modulators effectively decreased the daily discomfort due to dysmenorrhea.

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Use of fluconazole in women of reproductive age with vulvovaginal candidiasis

Medical Council ◽

10.21518/2079-701x-2018-13-96-102 ◽

2018 ◽

pp. 96-102

Author(s):

E. A. Mezhevitinova ◽

P. R. Abakarova ◽

Sh. M. Pogosyan

Keyword(s):

Quality Of Life ◽

Vulvovaginal Candidiasis ◽

Reproductive Age ◽

Common Disease ◽

Women Of Reproductive Age ◽

Recurrent Vulvovaginal Candidiasis ◽

Group I ◽

Relapse Therapy

Topicality: vulvovaginal candidiasis (VVC) is a common disease caused by the infectious damage of the vulva and vagina by yeast-like fungi from Candida genus. According to the literature, a VVC episode occurs in 75% of women, and 5-8% of them get a recurring course of the disease. Frequent recurrences of the disease may result in the psychosexual disorder and reduce the women’s quality of life and recurrent vulvovaginal candidiasis (VVC) therapy is still a very difficult task.Purpose of the study: evaluate the efficacy of fluconazole (150 mg) in acute and recurrent vulvovaginal candidiasis.Materials and methods:A total of 89 women of reproductive age with acute and recurrent HCV were enrolled in the study, which were subdivided into 2 groups: the first group included women with acute vulvovaginal candidiasis (AVVC) (n = 51), and the second group - women with recurrent vulvovaginal candidiasis (RVVC) (n = 38). The Group I (AVVC) received fluconazole 150 mg once. Depending on the prescribed therapy, the second group (RVVC) was subdivided into two subgroups: patients in the IIa subgroup received fluconazole 150 mg intravenously, three times, at intervals of 2 days, and women in the IIb subgroup received fluconazole 150 mg for a period of 6 months in addition to the three-fold intake of fluconazole weekly. The follow-up period was 6 months after the end of therapy, during which the frequency of VVC recurrence and the effectiveness of the therapy was evaluated.Results of the study: our data showed that all patients with acute VVC had a discontinuation of symptoms of the disease and a normalization of laboratory parameters after treatment with fluconazole, and after the anti-relapse therapy course the incidence of VVC recurrences was significantly lower compared to the period before anti-relapse therapy (p = 0.038). It was shown that all the investigated strains of C. albicans (100%) were sensitive to fluconazole, and resistance was detected only in 1 strain of C. glabrata and 1 strain of C. krusei.

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Prevalence and risk factors for dysmenorrhoea among nursing student and its impact on their quality of life

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20182483 ◽

2018 ◽

Vol 7 (7) ◽

pp. 2661 ◽

Cited By ~ 1

Author(s):

Shashikala Karanth ◽

S. R. Liya

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Nursing Students ◽

Menstrual Cycle ◽

Adolescent Girls ◽

Cycle Duration ◽

School Absenteeism ◽

Low Bmi ◽

The Mean

Background: Dysmenorrhea is an important health problem of adolescent girls, that affects their quality of life and it is one of the leading causes of repeated school absenteeism. The purposes of this study was to determine the prevalence and risk factors for dysmenorrhea among nursing students and its impact on their quality of life.Methods: A prospective study was carried out in St Johns Nursing College, Bengaluru.200 nursing students aged between 18-20 years were included. Standardized questionnaires were used to obtain relevant data. Data was analysed using Chi-sq. test, correlation and regression analysis by SPSS version 23.Results: The prevalence of dysmenorrhea was 62.5%. The mean age, age at menarche and, the mean PABC of the students were 18.7±0.48, 13.3±1.20 and 74.96±16.14 respectively, which is not significant. The average length of menstrual cycle was between 28-30 days, duration of bleeding as 3-5 days. Duration of sleep, regular menstrual cycle and low BMI exhibited positive correlation (p<0.05) while Family history and exercising habits did not exhibit significant effect. Dysmenorrhea was significantly associated with repeated school absenteeism (16%).Conclusions: Dysmenorrhoea is found to be highly prevalent among nursing students and is one of the leading causes of absenteeism. Regular cycle, duration of sleep and low BMI were significant risk factors for dysmenorrhea. Findings of present study suggest the need for educating adolescent girls on appropriate and effective management of dysmenorrhea.

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