scholarly journals Use of fluconazole in women of reproductive age with vulvovaginal candidiasis

2018 ◽  
pp. 96-102
Author(s):  
E. A. Mezhevitinova ◽  
P. R. Abakarova ◽  
Sh. M. Pogosyan
Keyword(s):  
Quality Of Life ◽  
Vulvovaginal Candidiasis ◽  
Reproductive Age ◽  
Common Disease ◽  
Women Of Reproductive Age ◽  
Recurrent Vulvovaginal Candidiasis ◽  
Group I ◽  
Relapse Therapy

Topicality: vulvovaginal candidiasis (VVC) is a common disease caused by the infectious damage of the vulva and vagina by yeast-like fungi from Candida genus. According to the literature, a VVC episode occurs in 75% of women, and 5-8% of them get a recurring course of the disease. Frequent recurrences of the disease may result in the psychosexual disorder and reduce the women’s quality of life and recurrent vulvovaginal candidiasis (VVC) therapy is still a very difficult task.Purpose of the study: evaluate the efficacy of fluconazole (150 mg) in acute and recurrent vulvovaginal candidiasis.Materials and methods:A total of 89 women of reproductive age with acute and recurrent HCV were enrolled in the study, which were subdivided into 2 groups: the first group included women with acute vulvovaginal candidiasis (AVVC) (n = 51), and the second group - women with recurrent vulvovaginal candidiasis (RVVC) (n = 38). The Group I (AVVC) received fluconazole 150 mg once. Depending on the prescribed therapy, the second group (RVVC) was subdivided into two subgroups: patients in the IIa subgroup received fluconazole 150 mg intravenously, three times, at intervals of 2 days, and women in the IIb subgroup received fluconazole 150 mg for a period of 6 months in addition to the three-fold intake of fluconazole weekly. The follow-up period was 6 months after the end of therapy, during which the frequency of VVC recurrence and the effectiveness of the therapy was evaluated.Results of the study: our data showed that all patients with acute VVC had a discontinuation of symptoms of the disease and a normalization of laboratory parameters after treatment with fluconazole, and after the anti-relapse therapy course the incidence of VVC recurrences was significantly lower compared to the period before anti-relapse therapy (p = 0.038). It was shown that all the investigated strains of C. albicans (100%) were sensitive to fluconazole, and resistance was detected only in 1 strain of C. glabrata and 1 strain of C. krusei. 

scholarly journals Recurrent Vulvovaginal Candidiasis

2021 ◽  
Vol 5 (5) ◽  
pp. 474-483
Author(s):  
Cyntya Sari Sovianti ◽  
Mutia Devi
Keyword(s):  
Quality Of Life ◽  
Topical Therapy ◽  
Predisposing Factors ◽  
Vulvovaginal Candidiasis ◽  
Suppressive Therapy ◽  
Recurrent Vulvovaginal Candidiasis ◽  
Candida Sp ◽  
Microbiological Examination ◽  
Culture Negative

Vulvovaginal candidiasis is a common fungal infection caused by Candida Sp, especially Candida albicans. Recurrent vulvovaginal candidiasis was defined as the occurrence of four or more episodes of vulvovaginal candidiasis ​​in 12 months period. As many as 9% of women from various populations have recurrent vulvovaginal candidiasis. Vulvovaginal candidiasis affects the quality of life, mental health, and sexual activity. There are many predisposing factors that caused recurrent vulvovaginal candidiasis, such as genetics, host, habit, idiopathic and non-albican candida microbes. Management of recurrent vulvovaginal candidiasis includes elimination of predisposing factors; mycological culture diagnosis and identification of specific Candida species; followed by microbiological examination to confirm the sensitivity of the azole group to Candida sp. Further, oral, or topical therapy should be continued until the patient is asymptomatic and culture-negative. Patients should receive induction therapy followed by maintenance suppressive therapy for six months.

Effect of combined oral contraceptive containing 17β—estradiol on female sexual function, depression and quality of life

2020 ◽  
Vol 18 (6) ◽  
pp. 43-48
Author(s):  
R. I. GABIDULLINA ◽  
◽  
E. I. GALIMYANOVA ◽  
V. I. EREMKINA ◽  
A. M. SHARAPOVA ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Contraceptive ◽  
Female Sexuality ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Combined Oral Contraceptive ◽  
Function Index ◽  
17Β Estradiol ◽  
Severity Of Depression

The purpose — to evaluate the effect of combined oral contraceptive containing 17β-estradiol on sexuality, severity of depression and quality of life in women of reproductive age. Material and methods. The study involved 53 women in need of contraception aged 18 to 50 years. For the contraceptive purpose women used COC containing 1,5 mg of 17 β -estradiol (E2) and 2,5 mg of nomegestrol acetate (NOMAC) (E2/NOMAC). The questionnaires used in the study are: Female Sexuality Function Index (FSFI-6), Beck Depression Inventory, SF-36 — for evaluating Health-Related Quality of Life. The survey was conducted before and after six months of E2/NOMAC intake; the correlations between the studied parameters and the level of sex hormones in patient’s blood sample were determined. Results. The intake of E2/NOMAC for 6 months did not have negative effect on Female Sexuality Function Index. At the same time, a statistically significant improvement up to 5 points was revealed in such parameters as sexual satisfaction (p = 0,03) and lubrication (p < 0,001). There was a significant decrease in the frequency and severity of depression measured by the Beck Depression Inventory. The Short Form-36 Health Survey revealed a tendency to improve the physical and mental health components of the quality of life (p> 0,05). The change in total testosterone level had a moderate negative relationship with the change in Female Sexuality Function Index (r = — 0,32; p = 0,02). Conclusion. The intake of combined oral contraceptive containing 17β-estradiol for 6 months was associated with no adverse impact on female sexuality and quality of life in women of reproductive age, and reduced the levels of frequency and severity of depression.

scholarly journals Recurrent Vulvovaginal Candidiasis

2021 ◽  
Vol 5 (3) ◽  
pp. 498-507
Author(s):  
Cyntya Sari Sovianti ◽  
Mutia Devi
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Topical Therapy ◽  
Predisposing Factors ◽  
Vulvovaginal Candidiasis ◽  
Suppressive Therapy ◽  
Recurrent Vulvovaginal Candidiasis ◽  
Candida Sp ◽  
Culture Negative

Vulvovaginal candidiasis is a common fungal infection caused by Candida Sp,especially Candida albicans. Recurrent vulvovaginal candidiasis was defined asthe occurrence of four or more episodes of vulvovaginal candidiasis in 12 monthsperiod. As many as 9% of women from various populations have recurrentvulvovaginal candidiasis. Vulvovaginal candidiasis affects the quality of life,mental health, and sexual activity. There are many predisposing factors thatcaused recurrent vulvovaginal candidiasis, such as genetics, host, habit,idiopathic and non-albican candida microbes. Management of recurrentvulvovaginal candidiasis includes elimination of predisposing factors; mycologicalculture diagnosis and identification of specific Candida species; followed bymicrobiological examination to confirm the sensitivity of the azole group toCandida sp. Further, oral, or topical therapy should be continued until the patientis asymptomatic and culture-negative. Patients should receive induction therapyfollowed by maintenance suppressive therapy for six months.

scholarly journals Bleeding

2020 ◽  
Author(s):  
Kizito Omona
Keyword(s):  
Quality Of Life ◽  
At Risk ◽  
Abdominal Pain ◽  
Sexual Intercourse ◽  
Pelvic Pain ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Abnormal Bleeding ◽  
Monthly Period

Fibroid, also called leiomyomas, is common tumor of the uterus. Usually, women of reproductive age are at risk of getting it. However, majority of these women develop fibroid (s) by the age of 50 years. This condition usually causes painful and unpleasant symptoms such as; heavy bleeding, prolonged periods, inter-menstrual bleeding, abdominal pain and cramps, anemia, pelvic pain and pain during sexual intercourse, among others. Abnormal bleeding, such as bleeding that occurs with fibroids and heavy periods, often lasts more than 10 days per month. This fibroid symptom involves persistent bleeding between cycles, which can severely impact one’s quality of life. Abnormal bleeding, especially in fibroids, can be taken as missing three or more periods in a woman who had been having regular monthly period, or periods that last less than 21 days or more than 35 days apart from each other. Another indication of an abnormal period is bleeding through multiple pads and tampons in a short amount of time.

Comparison of indicators quality of life in women after operative rehabilitation on uterine fibroids

2016 ◽  
pp. 94-97
Author(s):  
O. Makarchuk ◽  
◽  
G. Gavrilyuk ◽  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Uterine Fibroids ◽  
The Body ◽  
Reproductive Age ◽  
Control Group ◽  
Psychosomatic Disorders ◽  
Women Of Reproductive Age ◽  
Surgical Recovery

One of the most common benign hyperproliferative diseases of the female reproductive organs are uterine leiomyoma, the frequency of which, according to various literature in women of reproductive age is between 20% and 40%, and is the main indication for surgery, including removal of the organ. Long-term effects of surgical interventions for uterine fibroids have been the subject of numerous debates. In modern literature is not much research on the assessment of the quality of life both in organ treatment of uterine fibroids, and after surgical recovery. Quality of life have undoubtedly significant prognostic value and can be used in selecting the optimal treatment of uterine fibroids, as well as the development of individual approach to postoperative rehabilitation of patients. The objective: was the study of quality of life and the search for possible ways to improve in women after surgical healing uterine fibroids. Materials and methods. A survey of 80 women of reproductive age (study group), which was conducted without hysterectomy applications. Clinical and laboratory examination conducted in the dynamics of the postoperative period and at 6, 12 months and 3 years after surgical recovery. Assessment of comparative analysis require further formation of two groups comparing 20 patients with myoectomy and 20 women with no uterus amputation supravaginal applications. The control group consisted of 20 healthy patients. Assessment of quality of life survey conducted by using common clinical trials and monitoring at the individual questionnaire MOS 36- Item Short-Form Health Survey- MOS SF-36. Statistical analysis of the survey results was carried out using the software package Microsoft Office Excel and Statistica 6.0 for Windows. Results. In women, the main indicators of psycho-emotional and vegetative manifestations were most pronounced immediately after surgery and remained stable in three years with no significant deviations in the comparison group. Among the most frequently observed fatigue (76.25%), sleep disorders (88.75%), irritability and mood changes (76.25%) and emotional lability, anxiety and depressive symptoms. Of The results of evaluation of quality of life should be noted that first disturbed functioning role of women because of poor physical and emotional state, as evidenced by the significant differences obtained on the scale of General Health (GH) (overall health). Three years after the rapid improvement in women’s core group established stable condition posthisterektomy pronounced effect on quality of life. Thus, in total 33.75% of the principal groups characterized as low quality of life, compared with 5.0% of patients in the control group and 10,0% of women with myoectomy. Conclusions. The highest level of dissatisfaction with life studied patients presenting in health – 28.75% (23) cases, slightly less professional – 22.5% (18), emotional – 17.5% (17) and as in the sexual sphere – 13.75% (11) cases. That associated complications related symptoms posthisterektomy syndrome, increases the level of stress and hysterectomy as the body creates prerequisites for psychosomatic disorders. This action provides additional risk factors for the development of psychosocial distress in this group of patients. Key words: uterine fibroids, hysterectomy, posthisterektomy syndrome, psychosomatic disorders, quality of life.

The Quality of Life in the Women of Reproductive Age as Patients with Active Forms of Tuberculosis

10.12737/3314 ◽  
2014 ◽  
Vol 21 (1) ◽  
pp. 57-63 ◽  
Author(s):  
Камаев ◽  
I. Kamaev ◽  
Русановская ◽  
G. Rusanovskaya ◽  
Шпрыков ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pulmonary Tuberculosis ◽  
Life Quality ◽  
Reproductive Age ◽  
Control Group ◽  
Main Process ◽  
Women Of Reproductive Age ◽  
Healthy Women ◽  
Tuberculosis Disease

The authors assessed the quality of life of 263 women of reproductive age. The main group consisted of 139 women aged o18-44 as the patients with active pulmonary tuberculosis disease treated in 2011-2012, and the other group of comparison consisted of 124 healthy women of the same age. To assess the life quality the authors used Russian version of the SF-36 which included questions of medico- social nature. It was proved that all the life quality parameters of the women suffering from tuberculosis disease were reduced in comparison with the control group of the healthy women. The only exception was the pain syndrome for which the statistical significance wasn’t reached at all and the physical functioning was assessed at the lowest level. The life quality problem was identified almost in half of the women that proved by the obtained data. Analysis of quality of life of the women established that 25-34 years respondents had the highest reducing of the rates. The analyzed group of patients differed from the low level of the socio- economic independence relatively favorable structure of clinical tuberculosis forms but with a high frequency of tubercle bacilli discharging and detection of lung tissue destructing. Generally, women with pulmonary tuberculosis had numerous risk factors for disease and co-morbidities aggravating the main process. The unfavorable health and social hygienic characteristics of the analyzed group of patients contribute to late making a diagnosis and spreading the infection among the population, including the women of reproductive age. Therefore health care professionals need to make efforts to promote healthy lifestyle and prevention of tuberculosis with this contingent that will allow to prevent new cases of disease and to reduce morbidity. The aim of any disease treatment, including tuberculosis should be considered as acts to improve the life quality of patients in case of positive clinical dynamics. Therefore it is important to guide medical practice for the patients’ psychosomatic status correcting in the early stages of disease that will be able to solve health problems more successfully. Thereby, the authors think it is necessary to organize services; to open offices where patients could get psychosocial correction and rehabilitation, to train the specialists.

Endometriosis and Infertility: The Impact on Quality of Life and Mental Health

2017 ◽  
Vol 9 (2) ◽  
pp. 112-115 ◽  
Author(s):  
Salvatore Giovanni Vitale ◽  
Valentina Lucia La Rosa ◽  
Agnese Maria Chiara Rapisarda ◽  
Antonio Simone Laganà
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Multidisciplinary Approach ◽  
Well Being ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Fertility Problems ◽  
The Impact

Endometriosis is one of the most common gynaecological diseases and has an incidence of about 6%-10% in women of reproductive age. It has been estimated that 50% of women with fertility problems have endometriosis. The management of infertility associated with endometriosis is difficult and controversial and it is important to provide a multidisciplinary approach in order to reduce the impact of these diseases on psychological and emotive well-being of affected women, as much as possible.

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