Associations of Pediatric Asthma Adherence Questionnaire (PAAQ) with Spirometry and FeNO in Asthmatic Children

2019 ◽  
Vol 33 (3) ◽  
pp. 304-307
Author(s):  
Mayako Saito-Abe ◽  
Kiwako Yamamoto-Hanada ◽  
Fumi Ishikawa ◽  
Yukihiro Ohya
Keyword(s):  
Pediatric Asthma ◽  
Asthmatic Children

Pediatric asthma biomarkers in relation to mental disorders of asthmatic children and their caregivers

2016 ◽  
Vol 33 (S1) ◽  
pp. S385-S386
Author(s):  
E. Zaky ◽  
E. Fouda ◽  
E. Samir ◽  
F. Ahmed
Keyword(s):  
Mental Disorders ◽  
Disease Severity ◽  
Parental Stress ◽  
Pediatric Asthma ◽  
Cross Sectional Study ◽  
Inflammatory Disorder ◽  
Healthy Children ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Group I

BackgroundPediatric bronchial asthma as a chronic airway inflammatory disorder has a significant impact on asthmatic children both biologically and psychologically. On the other hand, parental stress and depression has been linked to pediatric asthma and claimed to play an important role in its morbidity.ObjectivesAssessment of pediatric asthma biomarkers as parameters of disease severity in relation to mental disorders of an Egyptian sample of asthmatic children and their caregivers.MethodologyThe current cross-sectional study comprised 60 Egyptian asthmatic children as Group I and 35 clinically healthy children of comparable age and sex as Group II. Thorough clinical evaluation and psychometric assessment were carried out for all enrolled children and their caregivers. In addition, pulmonary function testing and measurement of esinophilic count, IL-5, and total IgE were carried out for children of both studied groups.ResultsEnrolled asthmatics had significant elevation of all studied asthma biomarkers with significant reduction of measured pulmonary functions compared to controls. Furthermore, asthmatics had significantly more encountered poor self-esteem, clinically manifest anxiety, and psychosocial impairment compared to controls. Meanwhile, parents of studied asthmatics had higher frequency of severer grades of clinically manifest isolation, anxiety, depression, and stress. Strikingly, the severer the asthma, the more the elevation of studied asthma biomarkers, the severer the asthmatic child's and caregivers’ anxiety and depression, and the more the caregivers’ isolation and stress.ConclusionPediatric asthma biomarkers as parameters of disease severity has been proven to be linked to mental health impairment of asthmatic children and their caregivers.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Effect of the SARS-CoV-2 pandemic on the control and severity of pediatric asthma

2022 ◽  
Vol 50 (1) ◽  
pp. 99-103
Author(s):  
Silvia Sanchez-Garcia ◽  
Javier Ruiz-Hornillos ◽  
Marta Bernaola-Abraira ◽  
Alicia Habernau-Mena ◽  
Eva Maria Lasa ◽  
...  
Keyword(s):  
Viral Infections ◽  
Healthcare Providers ◽  
Pediatric Asthma ◽  
Care Providers ◽  
Asthmatic Children ◽  
Global Pandemic ◽  
Oral Corticosteroids ◽  
Tertiary Hospitals ◽  
Animal Dander ◽  
Age Range

Background: The novel disease caused by the new coronavirus SARS-CoV-2 has caused an unprecedented global pandemic. Care providers of asthmatic children are increasingly con-cerned; as viral infections are one of the primary triggers of asthma flare-up. However, the effect of SARS-CoV-2 as well as the generated worldwide lockdown on asthmatic children is unknown.Objective: The aim of this study was to analyze the effects of pandemic SARS-CoV-2 in pediat-ric asthma control.Material and Methods: A retrospective, open, transversal study was performed at five tertiary hospitals. Recruited patients were aged <18 years and had physician-diagnosed asthma. Information regarding the 2019 and 2020 seasons were provided.Results: Data were collected from 107 children (age range: 3–18 years, mean age: 12 years). Well-controlled asthma was observed in 58 (54.2%) patients in 2020 versus 30 (28%) in 2019, and 15 (14%) patients had poorly controlled asthma in 2020 versus 28 (26.2%) in 2019. In 2020, a decrease in exacerbations caused by allergies to pollen, dust mites, molds, and through other causes not related to SARS-CoV-2 infection was observed. An increase in exacerbations was observed due to animal dander, stress, physical exercise, and SARS-CoV-2 infection. Children had a reduced need for asthma-controlling medication, made fewer visits to healthcare pro-viders and had lesser need of treatment with oral corticosteroids if compared with the same season of 2019.Conclusion: Pediatric asthma control improved, the need for controller medication declined, and fewer visits to healthcare providers were made during the pandemic if compared with the 2019 season.

scholarly journals A study on HbA1c profile in children with asthma using inhaled corticosteroids

2017 ◽  
Vol 4 (3) ◽  
pp. 796 ◽  
Author(s):  
Sunil Daniel ◽  
Jose O.
Keyword(s):  
Blood Sugar ◽  
Inhaled Corticosteroids ◽  
Glycosylated Hemoglobin ◽  
Venous Blood ◽  
Pediatric Asthma ◽  
Total Study Population ◽  
Asthmatic Children ◽  
Children With Asthma ◽  
Study Population

Background: Inhaled corticosteroids (ICS) are the mainstay of treatment for persistent bronchial asthma in children. Even though ICS is comparatively safe, few systemic toxicities have been reported. We have conducted a study on HbA1c profile of 170 asthmatic children who are on ICS for atleast 6 months. Glycosylated hemoglobin (HbA1c), fasting blood sugar (FBS), Postprandial blood sugar (PPBS) levels were measured before initiating ICS and after 6 months using venous blood samples. HbA1c measured using immunoassay. The objective of the study was to detect prevalence of significant hyperglycemia among children with asthma who are on inhaled corticosteroids. Study design used as a prospective follow up study, setting of the study was to Pediatric asthma clinic, Govt. TDMCH, Alappuzha, Study population used Children between 3 to 12 years attending pediatric asthma clinic.Methods: Cumulative doses of ICS and bronchodialators were measured by providing an asthma diary to mark the dose of medication. FBS, PPBS, and HbA1c levels were measured before initiating ICS and after 6 months. To elucidate the assosiations comparisons between different parameters Chi-square test was used as non-parametric test. Student’s T- test was used to compare mean values between 2 groups and different groups. Initial and follow up two groups of HbA1c and ICS administrations were compared using paired and unpaired T-test.Results: There is a significant increase in the mean HbA1c of the total study population before and after treatment with ICS.Conclusions: Long term use of ICS can affect glucose metabolism of asthmatic children. 

scholarly journals Lung Ultrasound in Pediatric Asthma - Characterizing Baseline Findings Outside of Acute Exacerbations

2021 ◽  
Author(s):  
Noah Marzook ◽  
Francois Gagnon ◽  
Alexandre Deragon ◽  
David Zielinski ◽  
Adam Shapiro ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Lung Ultrasound ◽  
Pediatric Asthma ◽  
Primary Objective ◽  
Asthmatic Children ◽  
Pleural Line ◽  
Acute Exacerbations ◽  
The Right ◽  
B Lines ◽  
Lung Zone

Background: Lung ultrasound (LUS) has been shown to be an effective tool to rapidly diagnose certain causes of pediatric respiratory distress in the emergency department. However, very little is known about LUS findings in pediatric asthma outside of acute exacerbations. Objectives: The primary objective of this study was to characterize LUS findings in a cohort of pediatric patients with a definitive diagnosis of asthma, outside of an asthma exacerbation. Methods: Eligible patients, aged 6 to 17 years old and diagnosed with asthma, underwent LUS during an outpatient visit. LUS was conducted using a six-zone scanning protocol. A positive LUS was defined by one or more of the following: ≥3 B-lines per intercostal space, pulmonary consolidation and/or pleural anomaly. Images were interpreted by an expert sonographer blinded to patient clinical characteristics. Results: 52 patients were included. 10/52 patients had a positive LUS (19.2%, 95CI 8.3-30.1%). Of those with positive LUS findings, 8 had B lines, 7 had consolidations <1cm, 1 had a pleural line abnormality and 1 had a consolidation >1cm. Positive findings were seen in the right anterior and lateral zones in 60% of participants and were limited to 1-2 intercostal spaces within one lung zone in 100% of participants. Conclusion: To our knowledge, this is the first report of LUS findings in outpatient pediatric asthma. Positive LUS findings in asthmatic children can be seen outside of acute exacerbations. Such findings need to be taken into consideration when using LUS for the acute evaluation of a pediatric patient with asthma.

Pediatric asthma quality of life questionnaire (PAQLQ): Validation among asthmatic children in Thailand

2005 ◽  
Vol 0 (0) ◽  
pp. 051220035135011 ◽  
Author(s):  
Orapan Poachanukoon ◽  
Nualanong Visitsunthorn ◽  
Watcharee Leurmarnkul ◽  
Pakit Vichyanond
Keyword(s):  
Quality Of Life ◽  
Pediatric Asthma ◽  
Life Questionnaire ◽  
Asthmatic Children ◽  
Quality Of Life Questionnaire

scholarly journals A Prospective Study to Assess the Quality of Life in Children with Newly Diagnosed Asthma and Their Caregivers using the Pediatric Asthma Quality of Life Questionnaire

2020 ◽  
Vol 11 ◽  
pp. 215013272096127
Author(s):  
Monika Battula ◽  
Preethi Arunashekar ◽  
Vinoth Ponnurangam Nagarajan
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Pediatric Asthma ◽  
Clinical Severity ◽  
Life Questionnaire ◽  
Newly Diagnosed ◽  
Asthmatic Children ◽  
Quality Of Life Questionnaire ◽  
Significant Change

Objectives: The study aims to assess the quality of life (QOL) in newly diagnosed asthmatic children and their caregivers before and after treatment using mini pediatric asthma quality of life questionnaire (PAQLQ) and pediatric asthma caregivers quality of life questionnaire (PACQLQ) and to compare their quality of life with ACS (asthma clinical severity score). Materials and Methods: This prospective study was done among 99 children and their caregivers, who were interviewed using mini PAQLQ and PACQLQ on 2 occasions: at the time of inclusion and 4 weeks after treatment. During their clinic visit, asthma clinical severity scoring was done, and children were treated according to GINA (Global Initiative for Asthma). Results: After 4 weeks of treatment, there was a significant change in all domains of mini PAQLQ ( P < .001) and PACQLQ ( P < .001). In children, the change in the emotional domain after treatment was minimal when compared to other domains. When ACS was compared with mini PAQLQ and PACQLQ, children with well-controlled asthma had a better quality of life than partially-controlled asthmatic children ( P < .001) and there wasn’t a significant change in the quality of life of the caregivers after treatment ( P = .321) Conclusion: During treatment, QOL of newly diagnosed asthmatic children and their caregivers showed significant improvement but children lagged in their emotional domain. Despite medical intervention, these children also require psychological support and counseling. Also, caregivers didn’t perceive a change in their QOL when compared with ACS and it indicates that parent’s and child health-related quality of life should be taken as independent dimensions.

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