scholarly journals Perforated uterus

2018 ◽  
Vol 3 (1) ◽  
pp. 46-47
Author(s):  
Justus W Ngatia
Keyword(s):  
Early Detection ◽  
Pregnancy Loss ◽  
Uterine Perforation ◽  
Potential Complication ◽  
Major Health Problem ◽  
Major Health ◽  
Pregnancy Failure ◽  
Dilatation And Curettage ◽  
Early Pregnancy Failure

Early pregnancy failure is a major health problem worldwide which occurs in 15-20% of pregnancies. During evacuation, uterine perforation is a potential complication. Careful post-evacuation follow-up helps in early detection of perforation. Perforation often requires laparotomy or laparoscopy to repair the defect and evaluate for injury to adjacent organs. Our patient had pregnancy loss at 12 weeks and uterine perforation during a dilatation and curettage procedure. She had laparotomy, evacuation through the perforation site and uterine repair with good outcome.

scholarly journals Brain Studded with Innumerable Larger Stones: Starry Sky at Night Appearance: Multiple Calcified Giant Tuberculoma with 15 Years of Follow-up

2017 ◽  
Vol 06 (02) ◽  
pp. 155-158
Author(s):  
Guru Satyarthee ◽  
P. Chandra ◽  
A. Mahapatra
Keyword(s):  
Central Nervous System Involvement ◽  
Definitive Diagnosis ◽  
Shunt Surgery ◽  
Unique Case ◽  
Major Health Problem ◽  
Major Health ◽  
Vp Shunt ◽  
Cranial Ct ◽  
Rising Incidence

AbstractTuberculosis is rapidly reemerging as a major health problem due to rising incidence of HIV cases across the globe. Central nervous system involvement is rare, but rarely multiple intracerebral granulomas can occur or occasional solitary tuberculoma also develops. The authors report a unique case of 24-year-old woman suffering from pulmonary tuberculosis developed headache and vomiting. Cranial CT scan revealed multiple widespread deposit of intracranial granuloma of sizeable lesion mimicking starry sky at night appearance. Excision of one tuberculoma was done for confirmation of definitive diagnosis, and histopathology was suggestive of tuberculoma. The patient also underwent VP shunt surgery. At last follow-up at 15 years following surgery, she was doing well.

scholarly journals Chemical Dependence in Anaesthetic Registrars in Australia and New Zealand

1993 ◽  
Vol 21 (2) ◽  
pp. 151-155 ◽  
Author(s):  
A. M. Weeks ◽  
M. R. Buckland ◽  
E. B. Morgan ◽  
P. S. Myles
Keyword(s):  
New Zealand ◽  
Health Problem ◽  
Chemical Dependence ◽  
Chemically Dependent ◽  
Major Health Problem ◽  
Major Health

The Supervisors of Anaesthetic Training in Australia and New Zealand were surveyed and asked to report any cases of chemical dependence from anaesthetic registrars at their hospital from 1981 to 1991. From 83 questionnaires there were 65 (78%) returned. There were 14 departments (22%) with experience of one or more cases during this interval. Only five (7%) reported conducting a lecture or tutorial on the problem. The departmental reports covered 4425 registrar years of training and there were 17 cases reported. Of these, 13 were complete and are considered in detail. It is estimated that 1.3 % of those who entered anaesthetic training during the interval were recognised to become chemically dependent during their training. Follow-up was available on only six of the 13 registrars and only one was reported to have completed training. The results of this survey indicate that chemical dependence is already a major health problem amongst anaesthetic registrars in Australia and New Zealand.

scholarly journals Complete Stenosis of the Uretero Vesical Junction in Urogenital Tuberculosis: Management and Evolution

2021 ◽  
Vol 3 (1) ◽  
pp. 21-23
Author(s):  
O. Elidrissi ◽  
M. Rkik ◽  
W. Bai ◽  
Y. Ghannam ◽  
M. Dakir ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Health Problem ◽  
Disease Type ◽  
Ureteral Stenosis ◽  
Major Health Problem ◽  
Major Health ◽  
Urogenital Tuberculosis ◽  
The World

Urogenital tuberculosis continues to be a major health problem around the world due to the epidemic of HIV infection. We report the case of a 40-year-old patient followed for urogenital tuberculosis and who presented during her follow-up a complication of her disease type ureteral stenosis, managed by endoscopic route. We try through our work to focus on the value of surveillance after anti-bacillary treatment in order to watch for complications and act in an innocuous way.

scholarly journals Safety & efficacy of manual vacuum aspiration compared to dilatation & curettage in the management of early pregnancy failure

2017 ◽  
Vol 49 (1-2) ◽  
pp. 18-22 ◽  
Author(s):  
Rabiul Islam ◽  
Sankar Prosad Biswas ◽  
Dolly Halder ◽  
Kaniz Fatima
Keyword(s):  
Hospital Stay ◽  
Early Pregnancy ◽  
Gestational Age ◽  
High Tech ◽  
Major Health Problem ◽  
Pregnancy Failure ◽  
Medical College ◽  
Vacuum Aspiration ◽  
Early Pregnancy Failure ◽  
Manual Vacuum Aspiration

Background: Early pregnancy failure is a major health problem across the globe. This is particularly important for the woman of Bangladesh.Objective: The aim of our study was to evaluate the safety and efficacy of manual vacuum aspiration (MVA) compared to dilatation and curettage (D&C) in the management of first trimester abortion.Methods: This was a prospective randomised study done in Obstetrics & Gynaecology department of Jessore medical college & Khulna medical college. Over a period of one year from January 2014 to December 2014, a total of four hundred women presented with spontaneous miscarriage with gestational age < 12 weeks patients with no sign of septic abortion and no history of pregancy with fibroid uterus were included in the study.Results: These patients underwent random selection either MVA group (n = 200) or D&C group (n=200). Cases were compared with respect to age, parity, gestational age, risk, blood loss, time taken & complications. The distribution of age, parity & gestational age was similar in both groups. The mean duration of procedure was significantly higher (P<.0001) in D&C group compared to MVA group. The duration of hospital stay was significantly lower (P<.0001) in MVA group compared to D&C group. Similarly the cost of the procedure was significantly lower (P<.0001) in MVA group compared to D&C group.Conclusion: MVA is safe, effective, cheaper, less time consuming and requires shorter hospital stay. It does not require general anaesthesia and complication is also less than dilation and curettage. So it can be easily accessible to the woman of both rural and urban societies belonging to any socioeconomic strata specially where high tech equipments and power supply are not available.Bang Med J (Khulna) 2016; 49 : 18-22

scholarly journals A prospective observational study of the follow-up of medical management of early pregnancy failure

2019 ◽  
Vol 8 (12) ◽  
pp. 3998
Author(s):  
RN Preethi ◽  
Pushplata Kumari ◽  
Anuja Abraham ◽  
Swati Rathore ◽  
Santosh Benjamin ◽  
...  
Keyword(s):  
Observational Study ◽  
Early Pregnancy ◽  
Medical Management ◽  
Prospective Observational Study ◽  
Pregnancy Failure ◽  
Early Pregnancy Failure

scholarly journals Characterization and Formulation of Isoniazid for High-Dose Dry Powder Inhalation

Pharmaceutics ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 233 ◽  
Author(s):  
Imco Sibum ◽  
Paul Hagedoorn ◽  
Henderik W. Frijlink ◽  
Floris Grasmeijer
Keyword(s):  
Spray Drying ◽  
Pulmonary Delivery ◽  
High Dose ◽  
Dry Powder ◽  
Major Health Problem ◽  
Major Health ◽  
Pulmonary Administration ◽  
Causes Of Mortality ◽  
Spray Dried

Tuberculosis is a major health problem and remains one of the main causes of mortality. In recent years, there has been an increased interest in the pulmonary delivery of antibiotics to treat tuberculosis. Isoniazid is one of these antibiotics. In this study, we aimed to characterize isoniazid and formulate it into a dry powder for pulmonary administration with little or no excipient, and for use in the disposable Twincer® inhaler. Isoniazid was jet milled and spray dried with and without the excipient l-leucine. Physiochemical characterization showed that isoniazid has a low Tg of −3.99 ± 0.18 °C and starts to sublimate around 80 °C. Milling isoniazid with and without excipients did not result in a suitable formulation, as it resulted in a low and highly variable fine particle fraction. Spray drying pure isoniazid resulted in particles too large for pulmonary administration. The addition of 5% l-leucine resulted in a fraction <5 µm = 89.61% ± 1.77% from spray drying, which dispersed well from the Twincer®. However, storage stability was poor at higher relative humidity, which likely results from dissolution-crystallization. Therefore, follow up research is needed to further optimize this spray dried formulation.

scholarly journals Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profile

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Ariana Díaz ◽  
Natalia Santucci ◽  
Bettina Bongiovanni ◽  
Luciano D’Attilio ◽  
Claudia Massoni ◽  
...  
Keyword(s):  
T Regulatory Cells ◽  
Specific Treatment ◽  
Cell Immune Response ◽  
Regulatory Cells ◽  
Major Health Problem ◽  
Major Health ◽  
Tuberculosis Patients ◽  
Tb Treatment ◽  
Endocrine Profile

Tuberculosis (TB) is a major health problem requiring an appropriate cell immune response (IR) to be controlled. Since regulatory T cells (Tregs) are relevant in IR regulation, we analyzed Tregs variations throughout the course of TB treatment and its relationship with changes in immune-endocrine mediators dealing with disease immunopathology. The cohort was composed of 41 adult patients, 20 of them completing treatment and follow-up. Patients were bled at diagnosis (T0) and at 2 (T2), 4 (T4), 6 (T6), and 9 months following treatment initiation. Twenty-four age- and sex-matched healthy controls (HCo) were also included. Tregs (flow cytometry) from TB patients were increased at T0 (versus HCoP<0.05), showing even higher values at T2 (versus T0P<0.01) and T4 (versus T0P<0.001). While IL-6, IFN-γ, TGF-β(ELISA), and Cortisol (electrochemiluminescence, EQ) were augmented, DHEA-S (EQ) levels were diminished at T0 with respect to HCo, with cytokines and Cortisol returning to normal values at T9. Tregs correlated positively with IFN-γ(R=0.868,P<0.05) at T2 and negatively at T4 (R=-0.795,P<0.05). Lowered levels of proinflammatory cytokines together with an increased frequency of Tregs of patients undergoing specific treatment might reflect a downmodulatory effect of these cells on the accompanying inflammation.

scholarly journals Pott’s Disease in a 3 Years Old Italian Child: Case Report and Review of the Literature

2018 ◽  
Vol 10 (1) ◽  
pp. 101-107
Author(s):  
Alessandro Porta ◽  
Francesca Lizzoli ◽  
Elisabetta Racchi ◽  
Cristina Scaramuzza ◽  
Luciana Parola
Keyword(s):  
Case Report ◽  
Early Recognition ◽  
Bone Destruction ◽  
Developed Countries ◽  
Hiv Positive ◽  
Review Of The Literature ◽  
Major Health Problem ◽  
Major Health ◽  
Pott’S Disease

Introduction:Tuberculosis (TB) is currently a major health problem, in particular in developing countries and in HIV positive people. Tubercular spondylodiscitis is the most common type of skeletal TB, more frequent in children than adults. It is rarely reported in developed countries.Case Report:We describe a 3 years-old Italian girl who referred to our hospital with back pain and walking deficiency; she had a very good outcome with anti-tubercular treatment and orthopedic follow-up.Conclusion:Early recognition and treatment of this tubercular complication are very important due to its possible complications: bone destruction, spinal deformity, neurologic and orthopedic complications.

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