scholarly journals Reviewing the Potential Vectors and Hosts of African Swine Fever Virus Transmission in the United States

2019 ◽  
Vol 6 ◽  
Author(s):  
Andrew Golnar ◽  
Estelle Martin ◽  
Jillian Wormington ◽  
Rebekah Kading ◽  
Pete Teel ◽  
...  
2019 ◽  
Vol 19 (7) ◽  
pp. 512-524 ◽  
Author(s):  
Andrew J. Golnar ◽  
Estelle Martin ◽  
Jillian D. Wormington ◽  
Rebekah C. Kading ◽  
Pete D. Teel ◽  
...  

2019 ◽  
Vol 19 (7) ◽  
pp. 506-511 ◽  
Author(s):  
Jillian D. Wormington ◽  
Andrew Golnar ◽  
Karen C. Poh ◽  
Rebekah C. Kading ◽  
Estelle Martin ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Mariia Nefedeva ◽  
Ilya Titov ◽  
Sodnom Tsybanov ◽  
Alexander Malogolovkin

AbstractThe recombination is one of the most frequently identified drivers of double-stranded DNA viruses evolution. However, the recombination events in African swine fever virus (ASFV) genomes have been poorly annotated. We hypothesize that the genetic determinants of ASFV variability are potential hot-spots for recombination. Here, we analyzed ASFV serotype-specific locus (C-type lectin (EP153R) and CD2v (EP402R)) in order to allocate the recombination breakpoints in these immunologically important proteins and reveal driving forces of virus evolution. The recombinations were found in both proteins, mostly among ASFV strains from East Africa, where multiple virus transmission cycles are notified. The recombination events were essentially associated with the domain organization of proteins. The phylogenetic analysis demonstrated the lack of clonal evolution for African strains which conclusively support the significance of recombinations in the serotype-specific locus. In addition, the signature of adaptive evolution of these two genes, pN/pS > 1, was demonstrated. These results have implications for the interpretation of cross-protection potential between evolutionary distant ASFV strains and strongly suggest that C-type lectin and CD2v may experience substantial selective pressure than previously thought.


Author(s):  
D. Ragland ◽  
R. M. Pogranichniy ◽  
O. S. Yurchenko ◽  
V. V. Bashinskiy ◽  
A. P. Gerilovych ◽  
...  

With monetary support from the United States Department of Agriculture Foreign Agricultural Service (USDA FAS), an investigative effort was undertaken to document the biosecurity practices employed by commercial pig producers in Ukraine to prevent the introduction of African swine fever virus (ASFV) on their farms. The cohort of farms selected and evaluated were owned by producers who were active members of the Association of Ukrainian Pig Breeders (AUPB). The assessment of biosecurity policies and practices consisted of an interview and in-person completion of a questionnaire that evaluated various aspects of biosecurity practices used on pig farms in Ukraine. The results of the interviews and completion of survey questionnaires support the conclusion that Ukrainian pig producers recognize the importance of farm biosecurity as it relates to preventing ASFV introduction on their farms and all the participating farms had biosecurity policies that were in force at the time of completion of the questionnaire. However, the results also support the conclusion that significant gaps in understanding about biosecurity exists and that there is a need for more education of Ukrainian pig producers about this critical aspect of health management and disease control. The broad impact of the project detailed that prospective, more comprehensive work on Ukrainian pig farms is required to adequately assist producers with ASFV control and effective applications of biosecurity


Pathogens ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 168
Author(s):  
Rémi Pereira De Oliveira ◽  
Evelyne Hutet ◽  
Maxime Duhayon ◽  
Frédéric Paboeuf ◽  
Marie-Frédérique Le Potier ◽  
...  

Ornithodoros soft ticks are the only known vector and reservoir of the African swine fever virus, a major lethal infectious disease of Suidae. The co-feeding event for virus transmission and maintenance among soft tick populations has been poorly documented. We infected Ornithodoros moubata, a known tick vector in Africa, with an African swine fever virus strain originated in Africa, to test its ability to infect O. moubata through co-feeding on domestic pigs. In our experimental conditions, tick-to-tick virus transmission through co-feeding failed, although pigs became infected through the infectious tick bite.


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