scholarly journals Nanotechnology-Based Weapons to Combat Human Papillomavirus Infection Associated Diseases

2021 ◽  
Vol 9 ◽  
Author(s):  
Luyao Pan ◽  
Bingxin Li ◽  
Jiahua Chen ◽  
Haofeng Zhang ◽  
Xi Wang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Gene Therapy ◽  
Human Papillomavirus ◽  
Mammalian Cells ◽  
Hpv Infection ◽  
Associated Diseases ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Infected Cells ◽  
Clinical Problems

Persistent human papillomavirus (HPV) infection will eventually lead to clinical problems, varying from verrucous lesions to malignancies like cervical cancer, oral cancer, anus cancer, and so on. To address the aforementioned problems, nanotechnology-based strategies have been applied to detect the virus, prevent the interaction between virus and mammalian cells, and treat the virus-infected cells, due mainly to the unique physicochemical properties of nanoparticles. In this regard, many nanotechnology-based chemotherapies, gene therapy, vaccination, or combination therapy have been developed. In this Minireview, we outline the pathogenesis of HPV infection and the recent advances in nanotechnology-based weapons that can be applied in combating HPV-associated diseases.

scholarly journals Unresolved questions concerning human papillomavirus infection and transmission: a modelling perspective

Sexual Health ◽  
2010 ◽  
Vol 7 (3) ◽  
pp. 368 ◽  
Author(s):  
David G. Regan ◽  
David J. Philp ◽  
Edward K. Waters
Keyword(s):  
Cervical Cancer ◽  
Health Policy ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Acquired Immunity ◽  
Knowledge Gaps ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Potential Impact ◽  
Transmission Models

Mathematical transmission models are widely used to forecast the potential impact of interventions such as vaccination and to inform the development of health policy. Effective vaccines are now available for the prevention of cervical cancer and other diseases attributable to human papillomavirus (HPV). Considerable uncertainties remain regarding the characterisation of HPV infection and its sequelae, infectivity, and both vaccine-conferred and naturally-acquired immunity. In this review, we discuss the key knowledge gaps that impact on our ability to develop accurate models of HPV transmission and vaccination.

scholarly journals Can genital-tract human papillomavirus infection and cervical cancer be prevented with a vaccine?

2004 ◽  
Vol 6 (9) ◽  
pp. 1-21 ◽  
Author(s):  
Joakim Dillner ◽  
Darron R. Brown
Keyword(s):  
Cervical Cancer ◽  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Genital Tract ◽  
Vaccine Development ◽  
Hpv Infection ◽  
Prophylactic Vaccine ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Causative Relationship

Human papillomavirus (HPV) infection is the cause of squamous cell carcinoma of the uterine cervix. This causative relationship has provided the rationale and incentive for development of a prophylactic vaccine. Such a vaccine, if found to be effective, could reduce the need for cervical cancer screening and have a profound effect on the incidence of cervical and other anogenital cancers. This review begins by examining the basic biological and epidemiological principles relevant to the development of HPV preventative vaccines. It then summarises studies examining the use of vaccines to prevent HPV infection in animals and humans, and, finally, discusses some of the unanswered issues surrounding vaccine development against HPV infection and cervical cancer.

scholarly journals Relationship between human papillomavirus infection and cervical cancer progression

2015 ◽  
Vol 4 (1) ◽  
pp. 21-25
Author(s):  
Meichang Ai
Keyword(s):  
Cervical Cancer ◽  
Developing Countries ◽  
Human Papillomavirus ◽  
Cancer Progression ◽  
Malignant Tumors ◽  
Hpv Infection ◽  
Etiological Factors ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

Abstract Cervical cancer is one of the most common malignant tumors that threaten women’s life and health in both developed and developing countries. Diet and smoking are independent etiological factors of cervical cancer. Among many independent etiological factors, human papillomavirus (HPV) infection is the most important one. HPV infection is universal among women of appropriate ages, and only persistent HPV infection is considered necessary to cause cervical cancer.

Traditional Chinese Medicine Combined with Routine Nursing on Patients with Cervical Human Papillomavirus Infection

2021 ◽  
Vol 7 (6) ◽  
pp. 6415-6421
Author(s):  
Jing Ye ◽  
Hui Cheng
Keyword(s):  
Human Papillomavirus ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infection Rate ◽  
Hpv Infection ◽  
Common Disease ◽  
Postoperative Rehabilitation ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Cervical Human Papillomavirus

Cervical papillomavirus infection is a common disease in women. The risk of permanent infection is the main reason for cervical HPV and its advanced acanthosis. The last time, the incidence rate of cervical papillomavirus is only different from that of malignant tumor women. The trend of young tumors is more and more obvious. Therefore, the treatment of parasitic lesions is very important to prevent or reduce the occurrence of cervical HPV. This paper aims to study the effect of traditional Chinese medicine combined with routine nursing on patients with cervical human papillomavirus infection. The application of traditional Chinese medicine therapy to promote the postoperative rehabilitation of patients with cervical human papillomavirus infection has significant effect, which is of great significance for clinicians in the future work. In this paper, through the introduction of traditional Chinese medicine and traditional Chinese medicine oral and external use combined with routine nursing methods, through the follow-up experimental investigation method to study the cervical human papillomavirus infection rate and the effect of cervical human papillomavirus infection patients after operation, it is proved that the effect of traditional Chinese medicine oral and external use combined with routine nursing on cervical human papillomavirus infection patients is better. The results show that 54% of the cervical HPV infection rate makes people pay more and more attention to cervical HPV. The infection investigation and genotyping can effectively judge the prognosis of patients, which has extremely important clinical significance.

Human Papillomavirus Infection of the Cervix

2021 ◽  
pp. 170-174
Author(s):  
Jacqueline M. Mills ◽  
Elizabeth A. Stier
Keyword(s):  
Cervical Cancer ◽  
At Risk ◽  
Human Papillomavirus ◽  
Hpv Vaccine ◽  
Cervical Neoplasia ◽  
Hpv 16 ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Hpv Genotypes ◽  
Prophylactic Hpv Vaccine

In 1992 Lorincz et al. were the first to evaluate the clinicopathologic correlation with 11 recently identified human papillomavirus (HPV) genotypes: 31, 33, 35, 42, 43, 44, 45, 51, 52, 56, and 58. Using cervical samples from 8 studies that included specimens from 2627 women, HPV genotypes were categorized by the likelihood of association with grades of cervical neoplasia (from normal to cancer). These findings were the basis of the determination that (a) HPV causes cervical cancer, (b) detection of the cancer associated HPV genotypes could identify women at risk for cervical pre-cancer and cancer, and (c) a prophylactic HPV vaccine should include protection against (at least) HPV 16 and 18.

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