scholarly journals Image Descriptors for Weakly Annotated Histopathological Breast Cancer Data

2020 ◽  
Vol 2 ◽  
Author(s):  
Panagiotis Stanitsas ◽  
Anoop Cherian ◽  
Vassilios Morellas ◽  
Resha Tejpaul ◽  
Nikolaos Papanikolopoulos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Computer Vision ◽  
State Of The Art ◽  
Area Under The Curve ◽  
Multiple Instance Learning ◽  
Superior Performance ◽  
Breast Cancer Dataset ◽  
Cancer Dataset ◽  
Cancer Data ◽  
Learning Framework

Introduction: Cancerous Tissue Recognition (CTR) methodologies are continuously integrating advancements at the forefront of machine learning and computer vision, providing a variety of inference schemes for histopathological data. Histopathological data, in most cases, come in the form of high-resolution images, and thus methodologies operating at the patch level are more computationally attractive. Such methodologies capitalize on pixel level annotations (tissue delineations) from expert pathologists, which are then used to derive labels at the patch level. In this work, we envision a digital connected health system that augments the capabilities of the clinicians by providing powerful feature descriptors that may describe malignant regions.Material and Methods: We start with a patch level descriptor, termed Covariance-Kernel Descriptor (CKD), capable of compactly describing tissue architectures associated with carcinomas. To leverage the recognition capability of the CKDs to larger slide regions, we resort to a multiple instance learning framework. In that direction, we derive the Weakly Annotated Image Descriptor (WAID) as the parameters of classifier decision boundaries in a Multiple Instance Learning framework. The WAID is computed on bags of patches corresponding to larger image regions for which binary labels (malignant vs. benign) are provided, thus obviating the necessity for tissue delineations.Results: The CKD was seen to outperform all the considered descriptors, reaching classification accuracy (ACC) of 92.83%. and area under the curve (AUC) of 0.98. The CKD captures higher order correlations between features and was shown to achieve superior performance against a large collection of computer vision features on a private breast cancer dataset. The WAID outperform all other descriptors on the Breast Cancer Histopathological database (BreakHis) where correctly classified malignant (CCM) instances reached 91.27 and 92.00% at the patient and image level, respectively, without resorting to a deep learning scheme achieves state-of-the-art performance.Discussion: Our proposed derivation of the CKD and WAID can help medical experts accomplish their work accurately and faster than the current state-of-the-art.

scholarly journals Ensemble Comparative Study for Diagnosis of Breast Cancer Datasets

2018 ◽  
Vol 7 (4.15) ◽  
pp. 281
Author(s):  
Bibhuprasad Sahu ◽  
Sujata Dash ◽  
Sachi Nandan Mohanty ◽  
Saroj Kumar Rout
Keyword(s):  
Breast Cancer ◽  
Neural Network ◽  
Early Stage ◽  
Breast Cancer Dataset ◽  
Classification Rate ◽  
Cancer Dataset ◽  
Cancer Data ◽  
Cad System ◽  
Result Analysis ◽  
Sensitivity Specificity

Every disease is curable if a little amount of human effort is applied for early diagnosis. The death rate in world increases day by day as patient fail to detect it before it becomes chronic. Breast cancer is curable if detection is done at early stage before it spread across all part of body. Now-a-days computer aided diagnosis are automated assistance for the doctors to produce accurate prediction about the stage of disease. This study provided CAD system for diagnosis of breast cancer. This method uses Neural Network (NN) as a classifier model and PCA/LDA for dimension reduction method to attain higher classification rate. Multiple layers of neural network are applied to classify the breast cancer data. This system experiment done on Wisconsin breast cancer dataset (WBCD) from UCI repository. The dataset is divided into 2 parts train and test. With the result of accuracy, sensitivity, specificity, precision and recall the performance can be measured. The results obtained are this study is 97% using ANN and PCA-ANN, which is better than other state-of-art methods. As per the result analysis this system outperformed then the existing system.  

scholarly journals Evaluation of Modified Categorical Data Fuzzy Clustering Algorithm on the Wisconsin Breast Cancer Dataset

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Amir Ahmad
Keyword(s):  
Breast Cancer ◽  
Fuzzy Clustering ◽  
Clustering Algorithm ◽  
Distance Measure ◽  
Hamming Distance ◽  
Machine Learning Techniques ◽  
Breast Cancer Dataset ◽  
Cancer Dataset ◽  
Cancer Data ◽  
Feature Values

The early diagnosis of breast cancer is an important step in a fight against the disease. Machine learning techniques have shown promise in improving our understanding of the disease. As medical datasets consist of data points which cannot be precisely assigned to a class, fuzzy methods have been useful for studying of these datasets. Sometimes breast cancer datasets are described by categorical features. Many fuzzy clustering algorithms have been developed for categorical datasets. However, in most of these methods Hamming distance is used to define the distance between the two categorical feature values. In this paper, we use a probabilistic distance measure for the distance computation among a pair of categorical feature values. Experiments demonstrate that the distance measure performs better than Hamming distance for Wisconsin breast cancer data.

scholarly journals Toward a direct and scalable identification of reduced models for categorical processes

2017 ◽  
Vol 114 (19) ◽  
pp. 4863-4868 ◽  
Author(s):  
Susanne Gerber ◽  
Illia Horenko
Keyword(s):  
Breast Cancer ◽  
A Priori ◽  
Dynamical Model ◽  
Breast Cancer Dataset ◽  
Collective Variables ◽  
Cancer Dataset ◽  
Reduced Models ◽  
Tuning Parameters ◽  
Cancer Data ◽  
Machine Learning Applications

The applicability of many computational approaches is dwelling on the identification of reduced models defined on a small set of collective variables (colvars). A methodology for scalable probability-preserving identification of reduced models and colvars directly from the data is derived—not relying on the availability of the full relation matrices at any stage of the resulting algorithm, allowing for a robust quantification of reduced model uncertainty and allowing us to impose a priori available physical information. We show two applications of the methodology: (i) to obtain a reduced dynamical model for a polypeptide dynamics in water and (ii) to identify diagnostic rules from a standard breast cancer dataset. For the first example, we show that the obtained reduced dynamical model can reproduce the full statistics of spatial molecular configurations—opening possibilities for a robust dimension and model reduction in molecular dynamics. For the breast cancer data, this methodology identifies a very simple diagnostics rule—free of any tuning parameters and exhibiting the same performance quality as the state of the art machine-learning applications with multiple tuning parameters reported for this problem.

scholarly journals Breast Cancer Diagnosis using Sequential Pattern Mining

2020 ◽  
Vol 8 (6) ◽  
pp. 5515-5519
Keyword(s):  
Breast Cancer ◽  
Pattern Mining ◽  
Age Groups ◽  
Experimental Studies ◽  
Breast Cancer Diagnosis ◽  
Sequential Pattern ◽  
Breast Cancer Dataset ◽  
Cancer Dataset ◽  
Cancer Data ◽  
Abnormal Growth

Cancer is a disease very common to both rural and urban peoples. It is the abnormal growth of some body cells which then destroy the normal functioning of surrounding cells. Cancer has different stages and can be cured easily if diagnosed earlier. Breast Cancer is widespread among the women of different age groups which results untimely death of so many ladies. As the cause of every cancer occurs before its actual appearance in the human body, sequential pattern from cancer datasets can be useful for determining the cause of Breast Cancer before its actual occurrence in the women body. In this article, we put forward a technique for digging out such patterns from Breast Cancer data. The effectiveness of the proposed technique is demonstrated by the experimental studies made with a real Breast Cancer dataset

Design of novel multi filter union feature selection framework for breast cancer dataset

2021 ◽  
pp. 1063293X2110160
Author(s):  
Dinesh Morkonda Gunasekaran ◽  
Prabha Dhandayudam
Keyword(s):  
Breast Cancer ◽  
Feature Selection ◽  
Care Center ◽  
Feature Selection Method ◽  
Selection Method ◽  
Cancer Center ◽  
Breast Cancer Dataset ◽  
Data Set ◽  
Health Care Center ◽  
Cancer Data

Nowadays women are commonly diagnosed with breast cancer. Feature based Selection method plays an important step while constructing a classification based framework. We have proposed Multi filter union (MFU) feature selection method for breast cancer data set. The feature selection process based on random forest algorithm and Logistic regression (LG) algorithm based union model is used for selecting important features in the dataset. The performance of the data analysis is evaluated using optimal features subset from selected dataset. The experiments are computed with data set of Wisconsin diagnostic breast cancer center and next the real data set from women health care center. The result of the proposed approach shows high performance and efficient when comparing with existing feature selection algorithms.

scholarly journals Prediction of benign and malignant breast cancer using data mining techniques

2018 ◽  
Vol 12 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Vikas Chaurasia ◽  
Saurabh Pal ◽  
BB Tiwari
Keyword(s):  
Breast Cancer ◽  
Data Mining ◽  
Low Income ◽  
Prediction Models ◽  
Naive Bayes ◽  
Naïve Bayes ◽  
Low Income Countries ◽  
Breast Cancer Dataset ◽  
Cancer Dataset ◽  
Rbf Network

Breast cancer is the second most leading cancer occurring in women compared to all other cancers. Around 1.1 million cases were recorded in 2004. Observed rates of this cancer increase with industrialization and urbanization and also with facilities for early detection. It remains much more common in high-income countries but is now increasing rapidly in middle- and low-income countries including within Africa, much of Asia, and Latin America. Breast cancer is fatal in under half of all cases and is the leading cause of death from cancer in women, accounting for 16% of all cancer deaths worldwide. The objective of this research paper is to present a report on breast cancer where we took advantage of those available technological advancements to develop prediction models for breast cancer survivability. We used three popular data mining algorithms (Naïve Bayes, RBF Network, J48) to develop the prediction models using a large dataset (683 breast cancer cases). We also used 10-fold cross-validation methods to measure the unbiased estimate of the three prediction models for performance comparison purposes. The results (based on average accuracy Breast Cancer dataset) indicated that the Naïve Bayes is the best predictor with 97.36% accuracy on the holdout sample (this prediction accuracy is better than any reported in the literature), RBF Network came out to be the second with 96.77% accuracy, J48 came out third with 93.41% accuracy.

scholarly journals PERFORMANCE ANALYSIS OF BREAST CANCER CLASSIFICATION USING DECISION TREE CLASSIFIERS

2017 ◽  
Vol 9 (2) ◽  
pp. 19 ◽  
Author(s):  
P. Hamsagayathri ◽  
P. Sampath
Keyword(s):  
Breast Cancer ◽  
Decision Tree ◽  
Ductal Carcinoma ◽  
Research Work ◽  
The United States ◽  
Breast Cancer Dataset ◽  
Decision Tree Classifier ◽  
Cancer Dataset ◽  
Term Survival ◽  
Tree Classifier

Breast cancer is one of the dangerous cancers among world’s women above 35 y. The breast is made up of lobules that secrete milk and thin milk ducts to carry milk from lobules to the nipple. Breast cancer mostly occurs either in lobules or in milk ducts. The most common type of breast cancer is ductal carcinoma where it starts from ducts and spreads across the lobules and surrounding tissues. According to the medical survey, each year there are about 125.0 per 100,000 new cases of breast cancer are diagnosed and 21.5 per 100,000 women due to this disease in the United States. Also, 246,660 new cases of women with cancer are estimated for the year 2016. Early diagnosis of breast cancer is a key factor for long-term survival of cancer patients. Classification plays an important role in breast cancer detection and used by researchers to analyse and classify the medical data. In this research work, priority-based decision tree classifier algorithm has been implemented for Wisconsin Breast cancer dataset. This paper analyzes the different decision tree classifier algorithms for Wisconsin original, diagnostic and prognostic dataset using WEKA software. The performance of the classifiers are evaluated against the parameters like accuracy, Kappa statistic, Entropy, RMSE, TP Rate, FP Rate, Precision, Recall, F-Measure, ROC, Specificity, Sensitivity.

scholarly journals A Comparison Study of Goodness of Fit Tests of Logistic Regression in R: Simulation and Application to Breast Cancer Data

2020 ◽  
pp. 50-59
Author(s):  
El-Housainy A. Rady ◽  
Mohamed R. Abonazel ◽  
Mariam H. Metawe’e
Keyword(s):  
Breast Cancer ◽  
Logistic Regression ◽  
Sample Size ◽  
Null Hypothesis ◽  
Goodness Of Fit ◽  
Quadratic Term ◽  
Breast Cancer Dataset ◽  
Cancer Data ◽  
Interaction Term ◽  
Test Package

Goodness of fit (GOF) tests of logistic regression attempt to find out the suitability of the model to the data. The null hypothesis of all GOF tests is the model fit. R as a free software package has many GOF tests in different packages. A Monte Carlo simulation has been conducted to study two situations; the first, studying the ability of each test, under its default settings, to accept the null hypothesis when the model truly fitted. The second, studying the power of these tests when assumptions of sufficient linear combination of the explanatory variables are violated (by omitting linear covariate term, quadratic term, or interaction term). Moreover, checking whether the same test in different R packages had the same results or not. As the sample size supposed to affect simulation results, so the pattern of change of GOF tests results under different sample sizes as well as different model settings was estimated. All tests accept the null hypothesis (more than 95% of simulation trials) when the model truly fitted except modified Hosmer-Lemeshow test in "LogisticDx" package under all different model settings and Osius and Rojek’s (OsRo) test when the true model had an interaction term between binary and categorical covariates. In addition, le Cessie-van Houwelingen-Copas-Hosmer unweighted sum of squares (CHCH) test gave unexpected different results under different packages. Concerning the power study, all tests had a very low power when a departure of missing covariate existed. Generally, stukel’s test (package ’LogisticDX) and CHCH test (package "RMS") reached a power in detecting a missing quadratic term greater than 80% under lower sample size while OsRo test (package ’LogisticDX’) was better in detecting missing interaction term. Beside the simulation study, we evaluated the performance of GOF tests using the breast cancer dataset.

scholarly journals Breast Cancer Prediction using Machine Learning

2019 ◽  
Vol 8 (4) ◽  
pp. 4879-4881
Keyword(s):  
Breast Cancer ◽  
Random Forest ◽  
Data Science ◽  
Breast Cancer Dataset ◽  
Random Forest Algorithm ◽  
Medical Field ◽  
Cancer Dataset ◽  
Cancer Prediction ◽  
Time Consumption ◽  
Simulated Environment

One of the most dreadful disease is breast cancer and it has a potential cause for death in women. Every year, death rate increases drastically due to breast cancer. An effective way to classify data is through classification or data mining. This becomes very handy, especially in the medical field where diagnosis and analysis are done through these techniques. Wisconsin Breast cancer dataset is used to perform a comparison between SVM, Logistic Regression, Naïve Bayes and Random Forest. Evaluating the correctness in classifying data based on accuracy and time consumption is used to determine the efficiency of the algorithms, which is the main objective. Based on the result of performed experiments, the Random Forest algorithm shows the highest accuracy (99.76%) with the least error rate. ANACONDA Data Science Platform is used to execute all the experiments in a simulated environment.

scholarly journals Classifications of Breast Cancer Diagnosis using Machine Learning

2020 ◽  
Vol 14 ◽  
Keyword(s):  
Breast Cancer ◽  
Machine Learning ◽  
Random Forest ◽  
Breast Cancer Diagnosis ◽  
Performance Comparison ◽  
Support Vector ◽  
Breast Cancer Dataset ◽  
K Nearest Neighbors ◽  
Cancer Dataset ◽  
Machine Learning Classification

Breast Cancer (BC) is amongst the most common and leading causes of deaths in women throughout the world. Recently, classification and data analysis tools are being widely used in the medical field for diagnosis, prognosis and decision making to help lower down the risks of people dying or suffering from diseases. Advanced machine learning methods have proven to give hope for patients as this has helped the doctors in early detection of diseases like Breast Cancer that can be fatal, in support with providing accurate outcomes. However, the results highly depend on the techniques used for feature selection and classification which will produce a strong machine learning model. In this paper, a performance comparison is conducted using four classifiers which are Multilayer Perceptron (MLP), Support Vector Machine (SVM), K-Nearest Neighbors (KNN) and Random Forest on the Wisconsin Breast Cancer dataset to spot the most effective predictors. The main goal is to apply best machine learning classification methods to predict the Breast Cancer as benign or malignant using terms such as accuracy, f-measure, precision and recall. Experimental results show that Random forest is proven to achieve the highest accuracy of 99.26% on this dataset and features, while SVM and KNN show 97.78% and 97.04% accuracy respectively. MLP shows the least accuracy of 94.07%. All the experiments are conducted using RStudio as the data mining tool platform.

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