scholarly journals A Quantitative Comparison of Multispectral Refraction Topography and Autorefractometer in Young Adults

2021 ◽  
Vol 8 ◽  
Author(s):  
Yunru Liao ◽  
Zhenlan Yang ◽  
Zijing Li ◽  
Rui Zeng ◽  
Jing Wang ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
High Agreement ◽  
Intraclass Correlation Coefficients ◽  
Repeatability And Reproducibility ◽  
The Mean

Purpose: Purpose of this study is to evaluate the measuring consistency of central refraction between multispectral refraction topography (MRT) and autorefractometry.Methods: This was a descriptive cross-sectional study including subjects in Sun Yat-sen Memorial Hospital from September 1, 2020, to December 31, 2020, ages 20 to 35 years with a best corrected visual acuity of 20/20 or better. All patients underwent cycloplegia, and the refractive status was estimated with autorefractometer, experienced optometrist and MRT. We analyzed the central refraction of the autorefractometer and MRT. The repeatability and reproducibility of values measured using both devices were evaluated using intraclass correlation coefficients (ICCs).Results: A total of 145 subjects ages 20 to 35 (290 eyes) were enrolled. The mean central refraction of the autorefractometer was −4.69 ± 2.64 diopters (D) (range −9.50 to +4.75 D), while the mean central refraction of MRT was −4.49 ± 2.61 diopters (D) (range −8.79 to +5.02 D). Pearson correlation analysis revealed a high correlation between the two devices. The intraclass correlation coefficient (ICC) also showed high agreement. The intrarater and interrater ICC values of central refraction were more than 0.90 in both devices and conditions. At the same time, the mean central refraction of experienced optometrist was −4.74 ± 2.66 diopters (D) (range −9.50 to +4.75D). The intra-class correlation coefficient of central refraction measured by MRT and subjective refraction was 0.939.Conclusions: Results revealed that autorefractometry, experienced optometrist and MRT show high agreement in measuring central refraction. MRT could provide a potential objective method to assess peripheral refraction.

Assessing the Motor Status Score: A Scale for the Evaluation of Upper Limb Motor Outcomes in Patients after Stroke

2002 ◽  
Vol 16 (3) ◽  
pp. 283-289 ◽  
Author(s):  
Mark Ferraro ◽  
Jennifer Hogan Demaio ◽  
Jennifer Krol ◽  
Chris Trudell ◽  
Keren Rannekleiv ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Upper Limb ◽  
Pearson Correlation ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Pearson Correlation Coefficient ◽  
Maximum Score ◽  
Intraclass Correlation Coefficients ◽  
Upper Extremity Impairment ◽  
Motor Outcomes

The Motor Status Scale (MSS) measures shoulder, elbow (maximum score = 40), wrist, hand, and finger movements (maximum score = 42), and expands the measurement of upper extremity impairment and disability provided by the Fugl-Meyer (FM) score. This work examines the interrater reliability and criterion validity of the MSS performed in patients admitted to a rehabilitation hospital 21 ± 4 days after stroke. Using the MSS and the FM, 7 occupational therapists masked to each other’s judgments, evaluated 12 consecutive patients with stroke. Two therapists evaluated 6 additional patients on consecutive days. Intraclass correlation coefficients were significant for each group of raters for the shoulder/elbow and for the wrist/hand (P < 0.0001); test-retest measures were also significant for the shoulder/elbow (Pearson correlation coefficient r = 0.99, P < 0.004) and for the wrist/hand (Pearson correlation coefficient r = 0.99, P < 0.003). The internal item consistency for the overall MSS was significant (Cronbach alpha = 0.98, P < 0.0001). Finally the correlation between the MSS and the FM (R 2 = 0.964) was significant (P < 0.0001). The MSS affords a reliable and valid assessment of upper limb impairment and disability following stroke.

scholarly journals Is the BESTest at Its Best? A Suggested Brief Version Based on Interrater Reliability, Validity, Internal Consistency, and Theoretical Construct

2012 ◽  
Vol 92 (9) ◽  
pp. 1197-1207 ◽  
Author(s):  
Parminder K. Padgett ◽  
Jesse V. Jacobs ◽  
Susan L. Kasser
Keyword(s):  
Interrater Reliability ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Test Items ◽  
Intraclass Correlation Coefficients ◽  
Eyes Closed ◽  
Functional Reach ◽  
Hip Abductor

Background The Balance Evaluation Systems Test (BESTest) and Mini-BESTest are clinical examinations of balance impairment, but the tests are lengthy and the Mini-BESTest is theoretically inconsistent with the BESTest. Objective The purpose of this study was to generate an alternative version of the BESTest that is valid, reliable, time efficient, and founded upon the same theoretical underpinnings as the original test. Design This was a cross-sectional study. Methods Three raters evaluated 20 people with and without a neurological diagnosis. Test items with the highest item-section correlations defined the new Brief-BESTest. The validity of the BESTest, the Mini-BESTest, and the new Brief-BESTest to identify people with or without a neurological diagnosis was compared. Interrater reliability of the test versions was evaluated by intraclass correlation coefficients. Validity was further investigated by determining the ability of each version of the examination to identify the fall status of a second cohort of 26 people with and without multiple sclerosis. Results Items of hip abductor strength, functional reach, one-leg stance, lateral push-and-release, standing on foam with eyes closed, and the Timed “Up & Go” Test defined the Brief-BESTest. Intraclass correlation coefficients for all examination versions were greater than .98. The accuracy of identifying people from the first cohort with or without a neurological diagnosis was 78% for the BESTest versus 72% for the Mini-BESTest or Brief-BESTest. The sensitivity to fallers from the second cohort was 100% for the Brief-BESTest, 71% for the Mini-BESTest, and 86% for the BESTest, and all versions exhibited specificity of 95% to 100% to identify nonfallers. Limitations Further testing is needed to improve the generalizability of findings. Conclusions Although preliminary, the Brief-BESTest demonstrated reliability comparable to that of the Mini-BESTest and potentially superior sensitivity while requiring half the items of the Mini-BESTest and representing all theoretically based sections of the original BESTest.

The choice of chromogen and reliability of contact rhinoscopy in the irradiated nasopharynx

2007 ◽  
Vol 122 (2) ◽  
pp. 177-180 ◽  
Author(s):  
Martin W Pak ◽  
Samuel Chow ◽  
C A van Hasselt
Keyword(s):  
Methylene Blue ◽  
Squamous Metaplasia ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional ◽  
Vital Stain ◽  
Intraclass Correlation Coefficients ◽  
Observer Reliability ◽  
Blue Stain ◽  
The Mean

AbstractA cross-sectional randomised single blind study was conducted to assess how concentrations of chromogen (vital stain) and the characteristics of the assessors affect the assessment of contact rhinoscopy. Twenty-eight patients who had undergone external radiotherapy for nasopharyngeal carcinoma were assessed by contact rhinoscopy using 0.5 per cent and 1 per cent methylene blue stain on opposite sides of the nasopharynx. Three independent observers assessed the visual clarity of the 45 contact endoscopic images showing squamous metaplasia according to a visual analogue scale. The intraclass correlation coefficients were 0.916 to 0.957 and 0.839 to 0.964 for intra-observer reliability of assessors in the groups of 0.5 per cent and 1 per cent stains, respectively. The intraclass correlation coefficients for inter-observer reliability of assessors were 0.884 and 0.885 in the groups of 0.5 per cent and 1 per cent stains, respectively. The mean scores of clarity of the cellular details were statistically higher in the group of 1 per cent stain among all assessors. These results showed that the assessment of squamous metaplasia by contact endoscopy is highly reliable irrespective of the clinical experience and knowledge of histopathology of the assessors. One per cent methylene blue should be the vital stain of choice in contact endoscopy.

scholarly journals Test-Retest Reliability of the King-Devick Test in an Adolescent Population

2017 ◽  
Vol 52 (5) ◽  
pp. 439-445 ◽  
Author(s):  
Tyler J. Oberlander ◽  
Bernadette L. Olson ◽  
Lee Weidauer
Keyword(s):  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Testing Time ◽  
Cross Sectional ◽  
Healthy Adolescent ◽  
Retest Reliability ◽  
Intraclass Correlation Coefficients ◽  
Adolescent Population ◽  
Test Retest Reliability

Context:  The King-Devick (KD) test is a screening tool designed to assess cognitive visual impairments, namely saccadic rhythm, postconcussion. Test-retest reliability of the KD in a healthy adolescent population has not yet been established. Objective:  To investigate the overall test-retest reliability of the KD among a sample of healthy adolescents. Additionally, we sought to determine if sex and age influenced reliability. Design:  Cross-sectional study. Setting:  Secondary school. Patients or Other Participants:  Sixty-eight healthy adolescents, 41 boys (age = 15.4 ± 1.9 years) and 27 girls (age = 15.4 ± 1.9 years). Main Outcome Measure(s):  Participants completed the KD (version 1) at 3 testing sessions (days 1, 30, and 45) following standard instructions. We recorded total time to complete the reading of 3 cards for each participant during each testing session. Two-way random-effects intraclass correlation coefficients (ICCs) using single measurements repeated over time and repeatability coefficients were calculated. Linear mixed models were used to determine whether differences existed at each testing time and to examine whether changes that took place among visits were different by sex or age. Results:  Adolescents who completed the KD demonstrated acceptable reliability (ICC = 0.81; 95% confidence interval = 0.73, 0.87); however, the repeatability coefficient was large (±8.76 seconds). The sample demonstrated improvements between visits 1 and 2 (mean ± standard error = 4.3 ± 0.5 seconds, P &lt; .001) and between visits 2 and 3 (2.4 ± 0.5 seconds, P &lt; .001) for a total improvement of 6.9 seconds over 3 tests. No significant visit-by-sex or visit-by-age interactions were observed. Conclusions:  Despite the ICC being clinically acceptable, providers using the KD test for serial assessment of concussion in adolescents should be cautious in interpreting the results due to a large learning effect. Incorporating multiple measures can ensure accurate detection of sport concussion.

Pellucid marginal degeneration versus keratoconus: distinction with wide-field SD-OCT corneal sublayer pachymetry

2020 ◽  
pp. bjophthalmol-2020-316496
Author(s):  
Niklas Mohr ◽  
Mehdi Shajari ◽  
Daniel Krause ◽  
Stefan Kassumeh ◽  
Jakob Siedlecki ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Area Under The Curve ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Wide Field ◽  
Good Reliability ◽  
Cross Sectional ◽  
Intraclass Correlation Coefficients ◽  
Calculated Ratio ◽  
Sd Oct

PurposeTo evaluate the capability of wide-field spectral-domain optical coherence tomography (SD-OCT) corneal sublayer pachymetry to distinguish between keratoconus and pellucid marginal degeneration (PMD).MethodsThis prospective cross-sectional study included 69 eyes (59 with keratoconus and 10 with PMD) of 69 patients. All patients were examined three subsequent times with the RTVue XR system. Pachymetry maps of the total cornea (CT), the epithelium (ET) and the stroma were generated using the onboard software. For analysis of reliability, the coefficients of variation and intraclass correlation coefficients (ICC) were calculated. Receiver operating characteristic analyses were performed to elaborate the most accurate pachymetric parameters for distinguishing between PMD and keratoconus.ResultsOverall repeatability of (sublayer) pachymetry was comparably good in both keratoconus (ICC ranging between 0.827 and 0.986) and PMD (ICC ranging between 0.753 and 0.998). Measurement reliability in keratoconic eyes was a negative function of Kmax (p<0.05). As compared with keratoconus, PMD exhibited higher CT (526±31 µm vs 503±30 µm; p=0.02) and ET (56±7 µm vs 51±5 µm; p=0.02) in the inferotemporal 2–5 mm sector as well as lower ET in the inferior 7–9 mm sector (52±5 µm vs 57±5 µm; p<0.01). The calculated ratio between CT in the inferotemporal 2–5 mm and in the inferior 7–9 mm sector yielded the highest diagnostic accuracy for distinguishing between PMD and keratoconus with an area under the curve of 0.977 and an optimal cut-off value of 0.90.ConclusionWide-field SD-OCT corneal sublayer pachymetry showed good reliability in PMD and keratoconus and may be useful to differentiate between the two ectatic diseases.

Mobility levels of acute medical patients: Is behavioural mapping comparable to accelerometry?

2020 ◽  
pp. 026921552097034
Author(s):  
Yizhou Wu ◽  
Esther J Smits ◽  
Peter Window ◽  
Alice Beningfield ◽  
Venerina Johnston ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Inpatient Setting ◽  
Medical Patients ◽  
Cross Sectional ◽  
Financial Investment ◽  
Intraclass Correlation Coefficients ◽  
Mean Differences ◽  
Medical Wards

Objective: To (1) determine agreement between behavioural mapping and accelerometry for measuring mobility levels in an acute medical inpatient setting and to (2) explore and compare the required resources and costs for both methods. Design: Observational cross-sectional study Setting: Tertiary referral teaching hospital in Brisbane, Australia. Subjects: Adult patients admitted to two acute medical wards. Main measures: Mobility levels were recorded by behavioural mapping, and thigh and chest-worn accelerometers (ActivPAL). The level of agreement between the two methods was evaluated using the Intraclass Correlation Coefficients for each mobility level (i.e. lying, sitting, upright, standing and walking). Results: Nineteen patients (10 male (53%); mean(SD) age of 72(14) years) were included in the agreement analysis. The Intraclass Correlation Coefficients were high for ‘lying’ (ICC = 0.87), ‘sitting’ (ICC = 0.84) and ‘upright’ (ICC = 0.93), indicating good to excellent agreement between the two methods. For these mobility levels, mean differences between the two methods were small (<2%), with large standard deviations (up to 18%). Agreement was poor for ‘standing’ (ICC = 0.00) and ‘walking’ (ICC = 0.35). Both methods were labour-intensive, with labour costs of A$1,285/€798 (34 hours) for behavioural mapping and A$1,055/€655 (28 hours) for accelerometry. No further costs were involved in behavioural mapping, but clinical backfill was required. Accelerometry involved a financial investment for accelerometers (A$11,100/€6,894 for 22 ActivPAL devices). Conclusion: Agreement between behavioural mapping and accelerometry was good for measuring ‘lying’, ‘sitting’ and ‘upright’, but poor for ‘standing’ and ‘walking’ in an acute inpatient setting. Both behavioural mapping and accelerometry were labour-intensive, with high costs for the accelerometry equipment.

scholarly journals Reliability of the qualitative and semiquantitative nailfold videocapillaroscopy assessment in a systemic sclerosis cohort: a two-centre study

2010 ◽  
Vol 69 (6) ◽  
pp. 1092-1096 ◽  
Author(s):  
Vanessa Smith ◽  
Carmen Pizzorni ◽  
Filip De Keyser ◽  
Saskia Decuman ◽  
Jens T Van Praet ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Correlation Coefficient ◽  
Intraclass Correlation Coefficient ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Rater Agreement ◽  
Nailfold Videocapillaroscopy ◽  
Intraclass Correlation Coefficients ◽  
The Mean ◽  
Scleroderma Pattern

ObjectiveInvestigation of the reliability of the qualitative and semiquantitative scoring of nailfold videocapillaroscopy (NVC) assessment between two raters in a systemic sclerosis (SSc) cohort.MethodsTwo raters from different centres blindly assessed the NVC images of 71 consecutive patients with SSc qualitatively as belonging to the scleroderma spectrum (SDS) category (‘early’, ‘active’, ‘late’ scleroderma pattern or ‘scleroderma-like’ pattern) or to the ‘normal’ category and semiquantitatively by calculating the mean score for capillary loss, giant capillaries, microhaemorrhages and capillary ramifications. Inter-rater/intrarater agreement was assessed by calculation of the proportion of agreement and by κ coefficients. Rater agreement of mean score values of hallmark parameters was assessed by intraclass correlation coefficients.ResultsThe inter-rater/intrarater proportion of agreement to qualitatively assess an image as belonging to the SDS category or not was 90% and 96%, whereas the agreement to distinguish between only ‘early’, ‘active’ and ‘late’ scleroderma NVC patterns was 62% and 81%. The agreement of the semiquantitative scoring, as assessed by intraclass correlation coefficient, was 0.96 and 0.95 for capillary loss, 0.84 and 0.95 for giant capillaries, 0.90 and 0.95 for microhaemorrhages and 0.64 and 0.95 for capillary ramifications.ConclusionsThis is the first study to demonstrate reliability of the qualitative and semiquantitative NVC assessment in an SSc cohort between raters at different centres. Reliability of NVC assessment is essential for use of this tool in multicentre SSc trials.

scholarly journals Reliability of a rapid hematology stain for sputum cytology

2014 ◽  
Vol 40 (3) ◽  
pp. 250-258 ◽  
Author(s):  
Jéssica Gonçalves ◽  
Emilio Pizzichini ◽  
Marcia Margaret Menezes Pizzichini ◽  
Leila John Marques Steidle ◽  
Cristiane Cinara Rocha ◽  
...  
Keyword(s):  
Interobserver Agreement ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Standard Technique ◽  
Cross Sectional Study ◽  
Induced Sputum ◽  
Cell Counting ◽  
Kappa Statistics ◽  
Cross Sectional ◽  
Intraclass Correlation Coefficients

Objective: To determine the reliability of a rapid hematology stain for the cytological analysis of induced sputum samples. Methods: This was a cross-sectional study comparing the standard technique (May-Grünwald-Giemsa stain) with a rapid hematology stain (Diff-Quik). Of the 50 subjects included in the study, 21 had asthma, 19 had COPD, and 10 were healthy (controls). From the induced sputum samples collected, we prepared four slides: two were stained with May-Grünwald-Giemsa, and two were stained with Diff-Quik. The slides were read independently by two trained researchers blinded to the identification of the slides. The reliability for cell counting using the two techniques was evaluated by determining the intraclass correlation coefficients (ICCs) for intraobserver and interobserver agreement. Agreement in the identification of neutrophilic and eosinophilic sputum between the observers and between the stains was evaluated with kappa statistics. Results: In our comparison of the two staining techniques, the ICCs indicated almost perfect interobserver agreement for neutrophil, eosinophil, and macrophage counts (ICC: 0.98-1.00), as well as substantial agreement for lymphocyte counts (ICC: 0.76-0.83). Intraobserver agreement was almost perfect for neutrophil, eosinophil, and macrophage counts (ICC: 0.96-0.99), whereas it was moderate to substantial for lymphocyte counts (ICC = 0.65 and 0.75 for the two observers, respectively). Interobserver agreement for the identification of eosinophilic and neutrophilic sputum using the two techniques ranged from substantial to almost perfect (kappa range: 0.91-1.00). Conclusions: The use of Diff-Quik can be considered a reliable alternative for the processing of sputum samples.

Automated refraction after trifocal and trifocal toric intraocular lens implantation

2020 ◽  
pp. 112067212091484
Author(s):  
Laureano A Rementería-Capelo ◽  
Jorge L García-Pérez ◽  
Inés Contreras ◽  
Vanesa Blázquez ◽  
Javier Ruiz-Alcocer
Keyword(s):  
Intraocular Lens ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Intraocular Lenses ◽  
Toric Intraocular Lens ◽  
Cross Sectional ◽  
Intraclass Correlation Coefficients ◽  
Starting Point ◽  
Manifest Refraction

Background: To analyze the correlation between automated refraction and manifest refraction after implantation of a trifocal intraocular lens or its toric version. Methods: This cross-sectional study involved 105 eyes of 105 patients. Subjects were divided in two groups: 62 with trifocal (AcrySof PanOptix) and 43 with trifocal toric (AcrySof PanOptix Toric) intraocular lenses. Automated refraction was employed as starting point for obtaining the manifest refraction. Automated refraction and manifest refraction measurements were analyzed and compared using the vector analysis 3 months after the surgery. Results: In both groups, the higher differences between automated refraction and manifest refraction measurements were found for the cylinder and the spherical equivalent (M). Cylinder values for PanOptix were: −0.60 ± 0.36 D with automated refraction and −0.17 ± 38 D with manifest refraction ( p < 0.001); for PanOptix Toric, the values were: −0.49 ± 0.31 D with automated refraction and −0.05 ± 0.21 D with manifest refraction ( p < 0.001). M values for PanOptix were: −0.23 ± 0.31 D with automated refraction and −0.03 ± 0.16 D with manifest refraction ( p < 0.001); for PanOptix Toric, the values were: −0.13 ± 0.40 D with automated refraction and 0.01 ± 0.12 D with manifest refraction ( p < 0.001). For the PanOptix group, intraclass correlation coefficients were: 0.51 (sphere), 0.64 (cylinder), 0.42 (M), 0.62 (J0), and 0.37 (J45). For the PanOptix Toric group, the intraclass correlation coefficients were: 0.39 (sphere), 0.61 (cylinder), 0.39 (M), 0.53 (J0), and 0.09 (J45). Conclusion: The results of this study suggest that patients implanted with the trifocal and the trifocal toric intraocular lens under study showed similar automated refraction results between them, with a slight trend to more negative amounts of cylinder and M. Nevertheless, clinicians should carefully confirm all parameters of the refraction with manifest refraction.

scholarly journals Repeatability, Reproducibility, and Comparability of Subjective and Objective Measurements of Intraocular Forward Scattering in Healthy Subjects

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Ayaka Iijima ◽  
Kimiya Shimizu ◽  
Hidenaga Kobashi ◽  
Aya Saito ◽  
Kazutaka Kamiya
Keyword(s):  
Healthy Subjects ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Forward Scattering ◽  
Intraclass Correlation Coefficients ◽  
Spread Function ◽  
Good Repeatability ◽  
Repeatability And Reproducibility ◽  
The Mean ◽  
Scattering Index

Purpose. To assess the repeatability, reproducibility, and comparability of measurements of subjective and objective forward scattering in healthy subjects.Methods. We prospectively examined twenty eyes of 20 healthy volunteers (7 men and 13 women; ages, 28.4 ± 4.1 years). The logarithmic straylight value (log(s)) and the objective scattering index (OSI) were measured with a straylight meter (C-Quant) and a point-spread function meter (OQAS), respectively.Results. The 95% limits of agreement (LoA) between first and second measurements ranged from −0.211 to 0.207 for the C-Quant and from −0.302 to 0.477 for the OQAS. The intraclass correlation coefficients for the repeatability of the log(s) and OSI measurements were 0.815 and 0.926, respectively. The mean difference between examiners was −0.051 ± 0.133 (95% LoA; −0.311 to 0.209) for the C-Quant and 0.080 ± 0.307 (−0.522 to 0.682) for the OQAS. There was a modest, but significant, correlation between the log(s) and the OSI (Spearman correlation coefficientr=0.498,p=0.026).Conclusions. The C-Quant and the OQAS provide good repeatability and reproducibility, although the OQAS measurement provides a slightly higher ICC than the C-Quant measurement. The subjective forward scattering may be to some extent expressed in the objective forward scattering in healthy subjects.

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