scholarly journals Membrane Homeoviscous Adaptation in Sinorhizobium Submitted to a Stressful Thermal Cycle Contributes to the Maintenance of the Symbiotic Plant–Bacteria Interaction

2021 ◽  
Vol 12 ◽  
Author(s):  
Natalia Soledad Paulucci ◽  
Adriana Belén Cesari ◽  
María Alicia Biasutti ◽  
Marta Susana Dardanelli ◽  
María Angélica Perillo
Keyword(s):  
Lipid Bilayers ◽  
Sinorhizobium Meliloti ◽  
Symbiotic Interaction ◽  
Homeoviscous Adaptation ◽  
Temperature Changes ◽  
Thermal Changes ◽  
Cyclic Temperature ◽  
The One ◽  
Term Response

Here, we estimate fast changes in the fluidity of Sinorhizobium meliloti membranes submitted to cyclic temperature changes (10°C–40°C–10°C) by monitoring the fluorescence polarization (P) of DPH and TMA-DPH of the whole cell (WC) as well as in its outer (OM) and inner (IM) membranes. Additionally, the long-term response to thermal changes is demonstrated through the dynamics of the phospholipid and fatty acid composition in each membrane. This allowed membrane homeoviscous adaptation by the return to optimal fluidity levels as measured by the PDPH/TMA-DPH in WC, OM, IM, and multilamellar vesicles of lipids extracted from OM and IM. Due to probe-partitioning preferences and membranes’ compositional characteristics, DPH and TMA-DPH exhibit different behaviors in IM and OM. The rapid effect of cyclic temperature changes on the P was the opposite in both membranes with the IM being the one that exhibited the thermal behavior expected for lipid bilayers. Interestingly, only after the incubation at 40°C, cells were unable to recover the membrane preheating P levels when cooled up to 10°C. Solely in this condition, the formation of threads and nodular structures in Medicago sativa infected with S. meliloti were delayed, indicating that the symbiotic interaction was partially altered but not halted.

scholarly journals Energetic analysis of hard facing and weld cladding of an air powered drop hammer damaged ram

2010 ◽  
Vol 14 (suppl.) ◽  
pp. 269-284
Author(s):  
Vukic Lazic ◽  
Milorad Jovanovic ◽  
Aleksandar Sedmak ◽  
Srbislav Aleksandrovic ◽  
Dragan Milosavljevic ◽  
...  
Keyword(s):  
Thermal Fatigue ◽  
Complex Geometry ◽  
Impact Compression ◽  
Temperature Changes ◽  
Drop Hammer ◽  
Cyclic Temperature ◽  
Energetic Analysis ◽  
Weld Cladding ◽  
Variable Impact

This paper studies problems of hard facing of damaged and initially cracked mechanical engineering heavy parts of complex geometry such as large rams of air powered drop hammers. During long-term exploitation, these parts are subjected to thermal fatigue due to cyclic temperature changes and variable impact compression. Taking into consideration high ram costs and difficulties to purchase ram, the necessity of its reparation becomes obvious. The choices of the most suitable technologies of hard facing and welding of an initially cracked ram are also studied here. Besides the techno-economic analysis, an energetic analysis is performed as an additional criterion in assessment of the proposed technology.

scholarly journals The Impact of Selected Atmospheric Conditions on the Process of Abrasive Wear of CFRP

Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 3965 ◽  
Author(s):  
Aneta Krzyzak ◽  
Damian Racinowski ◽  
Robert Szczepaniak ◽  
Mateusz Mucha ◽  
Ewelina Kosicka
Keyword(s):  
Abrasive Wear ◽  
Atmospheric Conditions ◽  
Carbon Fabric ◽  
Temperature Changes ◽  
Cyclic Temperature ◽  
Research Findings ◽  
Long Term Impact ◽  
The Impact ◽  
Thermal Shocks

The aim of this study was to examine the impact of weathering and thermal shocks on the abrasive wear of epoxy resin composites reinforced with carbon fabric that are commonly used in aviation. The composite was exposed to degradation in an apparatus simulating weathering and thermal shocks and then subjected to an abrasion process, with and without the presence of water. The abrasive wear was controlled by checking the weight loss as well as by visual inspection. The research findings indicated a significant effect of the presence of water in the process of friction upon the deterioration of composite resistance to abrasion with regard to dry friction. The long-term impact of rapid cyclic temperature changes (temperature difference: from −56.5 °C to +60 °C) and a combined effect of UV-A (0.83 W/m2), along with condensation of vapor and an increased ambient temperature (above 50 °C), influenced an improvement in resistance to abrasive wear. The environment of thermal shocks diminished abrasive wear to a much smaller extent than after exploitation in an environment of weathering but both environments contributed to the degradation of the surface layer. Additionally, the environment with UV-A radiation resulted in exposure of the composite reinforcement already after four months of environmental impact.

Radioimmunotherapy for treatment of acute myeloid leukaemia and myelodysplastic syndrome

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Primary Tumour ◽  
The Other ◽  
Haematopoietic Stem Cell ◽  
Other Hand ◽  
Primary Reduction ◽  
The One ◽  
Acute Myeloid

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.

Hidden “holes” in the capital of banks and the supply of credit to the real sector of economy

2018 ◽  
pp. 49-68 ◽  
Author(s):  
M. E. Mamonov
Keyword(s):  
Credit Risk ◽  
The Other ◽  
Real Sector ◽  
Capital Management ◽  
Loan Loss ◽  
Short Term ◽  
The Real ◽  
Ex Post ◽  
The One

Our analysis documents that the existence of hidden “holes” in the capital of not yet failed banks - while creating intertemporal pressure on the actual level of capital - leads to changing of maturity of loans supplied rather than to contracting of their volume. Long-term loans decrease, whereas short-term loans rise - and, what is most remarkably, by approximately the same amounts. Standardly, the higher the maturity of loans the higher the credit risk and, thus, the more loan loss reserves (LLP) banks are forced to create, increasing the pressure on capital. Banks that already hide “holes” in the capital, but have not yet faced with license withdrawal, must possess strong incentives to shorten the maturity of supplied loans. On the one hand, it raises the turnovers of LLP and facilitates the flexibility of capital management; on the other hand, it allows increasing the speed of shifting of attracted deposits to loans to related parties in domestic or foreign jurisdictions. This enlarges the potential size of ex post revealed “hole” in the capital and, therefore, allows us to assume that not every loan might be viewed as a good for the economy: excessive short-term and insufficient long-term loans can produce the source for future losses.

Interrelationships between municipal spatial policy strategy and airport operation and development. Lodz Airport case study

2018 ◽  
Vol 59 (1) ◽  
pp. 65-79
Author(s):  
Katarzyna Nikorowicz-Zatorska
Keyword(s):  
Land Use ◽  
Urban Planning ◽  
Cultural Development ◽  
The Other ◽  
Local Authorities ◽  
Spatial Management ◽  
The One ◽  
Surrounding Areas

Abstract The present paper focuses on spatial management regulations in order to carry out investment in the field of airport facilities. The construction, upgrades, and maintenance of airports falls within the area of responsibility of local authorities. This task poses a great challenge in terms of organisation and finances. On the one hand, an active airport is a municipal landmark and drives local economic, social and cultural development, and on the other, the scale of investment often exceeds the capabilities of local authorities. The immediate environment of the airport determines its final use and prosperity. The objective of the paper is to review legislation that affects airports and the surrounding communities. The process of urban planning in Lodz and surrounding areas will be presented as a background to the problem of land use management in the vicinity of the airport. This paper seeks to address the following questions: if and how airports have affected urban planning in Lodz, does the land use around the airport prevent the development of Lodz Airport, and how has the situation changed over the time? It can be assumed that as a result of lack of experience, land resources and size of investments on one hand and legislative dissonance and peculiar practices on the other, aviation infrastructure in Lodz is designed to meet temporary needs and is characterised by achieving short-term goals. Cyclical problems are solved in an intermittent manner and involve all the municipal resources, so there’s little left to secure long-term investments.

Aspects of the Evolution of the Romanian Tourists’ Preferences Concerning the Domestic Tourist Destinations

2019 ◽  
Vol 10 (1) ◽  
pp. 21-28
Author(s):  
Aniela Bălăcescu ◽  
Radu Șerban Zaharia
Keyword(s):  
Logistic Model ◽  
Local Level ◽  
Medium Term ◽  
Tourist Destinations ◽  
Tourism Management ◽  
Production And Consumption ◽  
On Line ◽  
The One ◽  
Long Term Studies

Abstract Tourist services represent a category of services in which the inseparability of production and consumption, the inability to be storable, the immateriality, and last but not least non-durability, induces in tourism management a number of peculiarities and difficulties. Under these circumstances the development of medium-term strategies involves long-term studies regarding on the one hand the developments and characteristics of the demand, and on the other hand the tourist potential analysis at regional and local level. Although in the past 20 years there has been tremendous growth of on-line booking made by household users, the tour operators agencies as well as those with sales activity continue to offer the specific services for a large number of tourists, that number, in the case of domestic tourism, increased by 1.6 times in case of the tour operators and by 4.44 times in case of the agencies with sales activity. At the same time, there have been changes in the preferences of tourists regarding their holiday destinations in Romania. Started on these considerations, paper based on a logistic model, examines the evolution of the probabilities and scores corresponding to the way the Romanian tourists spend their holidays on the types of tourism agencies, actions and tourist areas in Romania.

When Political Transitions Work

2018 ◽  
Author(s):  
Fanie du Toit
Keyword(s):  
South African ◽  
Well Being ◽  
Transition To Democracy ◽  
Political Transitions ◽  
Political Reconciliation ◽  
Peace Processes ◽  
Theoretical Approaches ◽  
African Experience ◽  
The One

Reconciliation emphasizes relationships as a crucial ingredient of political transition; this book argues for the importance of such a relational focus in crafting sustainable political transitions. Section I focuses on South Africa’s transition to democracy—how Mandela and De Klerk persuaded skeptical constituencies to commit to political reconciliation, how this proposal gained momentum, and how well the transition resulted in the goal of an inclusive and fair society. In developing a coherent theory of reconciliation to address questions such as these, I explain political reconciliation from three angles and thereby build a concept of reconciliation that corresponds largely with the South African experience. In Section II, these questions lead the discussion beyond South Africa into some of the prominent theoretical approaches to reconciliation in recent times. I develop typologies for three different reconciliation theories: forgiveness, agonism, and social restoration. I conclude in Section III that relationships created through political reconciliation, between leaders as well as between ordinary citizens, are illuminated when understood as an expression of a comprehensive “interdependence” that precedes any formal peace processes between enemies. I argue that linking reconciliation with the acknowledgment of interdependence emphasizes that there is no real alternative to reconciliation if the motivation is the long-term well-being of one’s own community. Without ensuring the conditions in which an enemy can flourish, one’s own community is unlikely to prosper sustainably. This theoretical approach locates the deepest motivation for reconciliation in choosing mutual well-being above the one-sided fight for exclusive survival at the other’s cost.

Chilling Out

2018 ◽  
Author(s):  
Roy Livermore
Keyword(s):  
Plate Tectonics ◽  
Volcanic Eruptions ◽  
Atmospheric Temperature ◽  
Ocean Currents ◽  
Mountain Ranges ◽  
Continental Rifts ◽  
Earth’S Climate ◽  
The One ◽  
Tectonic Forces

The Earth’s climate changes naturally on all timescales. At the short end of the spectrum—hours or days—it is affected by sudden events such as volcanic eruptions, which raise the atmospheric temperature directly, and also indirectly, by the addition of greenhouse gases such as water vapour and carbon dioxide. Over years, centuries, and millennia, climate is influenced by changes in ocean currents that, ultimately, are controlled by the geography of ocean basins. On scales of thousands to hundreds of thousands of years, the Earth’s orbit around the Sun is the crucial influence, producing glaciations and interglacials, such as the one in which we live. Longer still, tectonic forces operate over millions of years to produce mountain ranges like the Himalayas and continental rifts such as that in East Africa, which profoundly affect atmospheric circulation, creating deserts and monsoons. Over tens to hundreds of millions of years, plate movements gradually rearrange the continents, creating new oceans and destroying old ones, making and breaking land and sea connections, assembling and disassembling supercontinents, resulting in fundamental changes in heat transport by ocean currents. Finally, over the very long term—billions of years—climate reflects slow changes in solar luminosity as the planet heads towards a fiery Armageddon. All but two of these controls are direct or indirect consequences of plate tectonics.

Preaching and Sermons

2017 ◽  
Author(s):  
Robert H. Ellison
Keyword(s):  
Eighteenth Century ◽  
North Atlantic ◽  
Religious Revival ◽  
Early Nineteenth Century ◽  
Denominational Identity ◽  
The North ◽  
The North Atlantic ◽  
The One ◽  
The Impact

Prompted by the convulsions of the late eighteenth century and inspired by the expansion of evangelicalism across the North Atlantic world, Protestant Dissenters from the 1790s eagerly subscribed to a millennial vision of a world transformed through missionary activism and religious revival. Voluntary societies proliferated in the early nineteenth century to spread the gospel and transform society at home and overseas. In doing so, they engaged many thousands of converts who felt the call to share their experience of personal conversion with others. Though social respectability and business methods became a notable feature of Victorian Nonconformity, the religious populism of the earlier period did not disappear and religious revival remained a key component of Dissenting experience. The impact of this revitalization was mixed. On the one hand, growth was not sustained in the long term and, to some extent, involvement in interdenominational activity undermined denominational identity; on the other hand, Nonconformists gained a social and political prominence they had not enjoyed since the middle of the seventeenth century and their efforts laid the basis for the twentieth-century explosion of evangelicalism in Africa, Asia, and South America.

Modeling of unforced demand response programs

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hassan Jalili ◽  
Pierluigi Siano
Keyword(s):  
Demand Response ◽  
Load Shifting ◽  
Response Models ◽  
Temperature Changes ◽  
Proposed Model ◽  
Equipment Failures ◽  
Demand Response Programs ◽  
Simultaneous Implementation ◽  
Long Term Studies

Abstract Demand response programs are useful options in reducing electricity price, congestion relief, load shifting, peak clipping, valley filling and resource adequacy from the system operator’s viewpoint. For this purpose, many models of these programs have been developed. However, the availability of these resources has not been properly modeled in demand response models making them not practical for long-term studies such as in the resource adequacy problem where considering the providers’ responding uncertainties is necessary for long-term studies. In this paper, a model considering providers’ unavailability for unforced demand response programs has been developed. Temperature changes, equipment failures, simultaneous implementation of demand side management resources, popular TV programs and family visits are the main reasons that may affect the availability of the demand response providers to fulfill their commitments. The effectiveness of the proposed model has been demonstrated by numerical simulation.

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