scholarly journals Dietary Risk-Related Colorectal Cancer Burden: Estimates From 1990 to 2019

2021 ◽  
Vol 8 ◽  
Author(s):  
Yujiao Deng ◽  
Bajin Wei ◽  
Zhen Zhai ◽  
Yi Zheng ◽  
Jia Yao ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Dietary Factors ◽  
Cancer Death ◽  
Dietary Factor ◽  
Cancer Burden ◽  
Targeted Interventions ◽  
Dietary Risk Factors ◽  
Dietary Risk ◽  
Life Years

Background: Colorectal cancer remains a public health problem worldwide. Dietary risk factors play a key role in the carcinogenesis and progression of colorectal cancer. This study aimed to explore the geographical and temporal trends in various dietary factor-related colorectal cancers.Methods: Data were extracted from the Global Burden of Disease (GBD) 2019 study, including the deaths, disability-adjusted life-years (DALYs), age-standardized rate (ASR), and summary exposure value (SEV) among 4 world regions, 11 age groups, 21 regions, and 204 countries and territories between 1990 and 2019. The estimated annual percentage changes (EAPCs) were calculated to evaluate the variation trend of ASR.Results: Dietary factors were the leading cause of colorectal cancer death and DALY rate, regardless of age. Dietary factor-related deaths and DALYs accounted for 32 and 34% of global colorectal cancer, respectively. Further analysis showed that low whole grain intake remained the leading cause of cancer death and DALY rate, followed by milk and calcium. Diets that were low in whole grains, milk, and calcium accounted for 81.61% of deaths and 81.64% of DALYs. Deaths and DALYs of dietary factors related to colorectal cancer grew by half from 1990 to 2019. All ASRs remained higher for men than women. Asia carried the highest colorectal cancer burden attributed to dietary risks, especially for East Asia [age-standardized death rate (ASDR): EAPC = 1.15, 95% CI:0.88–1.42; DALY: EAPC = 1.08, 95% CI:0.82–1.34]. The heavy burden also existed in high-middle and middle socio-demographic index (SDI) quintiles. China has always had the highest deaths and DALYs of colorectal cancer attributable to dietary risks, followed by the USA, India, and Japan.Conclusions: Large variations existed in the dietary risk-related colorectal cancer burdens among sexes, regions, and countries. More targeted interventions to address modifiable dietary risk factors would save 32% of deaths and 34% of DALYs for colorectal cancer.

Abstract P060: Major Dietary Risk Factors for Chronic Diseases: A Systematic Review of the Current Evidence for Causal Effects and Effect Sizes

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Shahab Khatibzadeh ◽  
Renata Micha ◽  
Ashkan Afshin ◽  
Mayuree Rao ◽  
Mohammad Y Yakoob ◽  
...  
Keyword(s):  
Risk Factors ◽  
Dose Response ◽  
Convincing Evidence ◽  
Dietary Factors ◽  
Causal Effects ◽  
Effect Sizes ◽  
Current Evidence ◽  
Dietary Risk Factors ◽  
Dietary Risk ◽  
Meta Analyses

Background: Diet habits contribute to development of CVD and diabetes. Estimating the impact of diet on these diseases requires identification and quantification of causal effects of dietary factors. Objectives: To assess major dietary risk factors for CVD and diabetes, evaluate current evidence for causal effects, and identify the best unbiased effect estimates on risk. Methods: For multiple dietary risk factors, we evaluated WHO and similar criteria as part of the Global Burden of Diseases (GBD) study to assess probable or convincing evidence for causal effects, including consistency, dose-response, plausibility, and temporality. We performed systematic searches of online databases from 2008 to 2011, including hand-searches of references and author contacts, to identify systematic reviews and meta-analyses of well-designed observational or interventional studies. Meta-analyses were evaluated based on number of studies, design, definition of diet factors and outcomes, sample size, number of events, length of follow-up, statistical methods, evidence of bias, and control for confounders. Meta-analyses with largest numbers of studies and events and least evidence for bias were identified. Effect sizes and uncertainty were quantified per defined units of exposure, including pooling of categorical dose-response estimates using fixed-effects generalized least squares for trend estimation (GLST). Results: We identified 15 dietary risk factors having probable or convincing evidence of causal effects on CVD or diabetes. For 13, data were identified to provide the best pooled unbiased effect size on disease (Table). Conclusions: This systematic evaluation provides the best evidence-based quantitative estimates of the effects of major dietary factors on CVD and diabetes. These findings enable estimation of quantitative impacts on diseases burdens of suboptimal intakes of these factors in specific populations, and also highlight gaps in knowledge related to causality or effect sizes of other dietary factors.

scholarly journals Contribution of specific dietary factors to CHD in US females

2009 ◽  
Vol 13 (2) ◽  
pp. 154-162 ◽  
Author(s):  
Nga Tran ◽  
Leila Barraj
Keyword(s):  
Risk Factors ◽  
Risk Reduction ◽  
Dietary Cholesterol ◽  
Dietary Factors ◽  
Health Study ◽  
Relative Risks ◽  
Dietary Risk Factors ◽  
Dietary Risk ◽  
Chd Risk ◽  
Chd Risk Factors

AbstractObjectiveTo estimate dietary cholesterol contribution to CHD risk among US females, relative to other dietary risk factors.DesignA risk apportionment model was applied to apportion CHD risk shares among the lifestyle and dietary risk factors.SettingThe model was implemented using relative risks from the Nurses’ Health Study and data on CHD risk factors and consumption from the National Health and Nutrition Examination Survey 1999–2002.SubjectsUS females aged 25 years or older.ResultsOn average, poor diet contributes 20 % of the CHD risk relative to obesity, inactivity and smoking, of which trans fat intake contributes 2·9 %, dietary cholesterol 1·5 % and 16 % is due to low consumption of nutrients, i.e. MUFA (1·5 %), PUFA (1·7 %), marine n-3 fatty acids (2·7 %), α-linolenic acid (1·1 %), dietary fibre (2·4 %), vitamin B6 (4·1 %), vitamin C (0·5 %) and folate (1·8 %).ConclusionsReducing trans fat and dietary cholesterol intakes could lead to CHD reduction, but greater risk reduction may be achieved by improving intakes of heart-healthy nutrients currently deficient in US females’ diets. Total diet consideration is essential in any CHD risk reduction strategy.

scholarly journals 303. Dietary risk factors of colorectal cancer from ayurvedic perspective

2018 ◽  
Vol 9 (2) ◽  
pp. S29
Author(s):  
Vineeta Awalkanthe ◽  
Sadanand Sardeshmukh ◽  
Vineeta Deshmukh ◽  
Vasanti Godse ◽  
Arvind Kulkarni ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Dietary Risk Factors ◽  
Dietary Risk

Fiber, Fat, and Colorectal Cancer: New Insight into Modifiable Dietary Risk Factors

2019 ◽  
Vol 21 (11) ◽  
Author(s):  
Soeren Ocvirk ◽  
Annette S. Wilson ◽  
Corynn N. Appolonia ◽  
Timothy K. Thomas ◽  
Stephen J. D. O’Keefe
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Dietary Risk Factors ◽  
Dietary Risk ◽  
Insight Into

scholarly journals Dietary risk factors for colorectal cancer in Brazil: a case control study

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Sandro Nunes Angelo ◽  
Gustavo J. Lourenço ◽  
Daniéla O. Magro ◽  
Helvia Nascimento ◽  
Rogério A. Oliveira ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Dietary Risk Factors ◽  
Dietary Risk ◽  
Control Study

scholarly journals Knowledge and Awareness of Colorectal Cancer among University Students in Oman

2021 ◽  
Author(s):  
Rajani Ranganath ◽  
Lujaina Salim Saud Al-maamari ◽  
Amnia Ali Rashid Al Saidi ◽  
Ali Haider Baquer Al Dujaili ◽  
Mohammed Al-Fatih Mahmood
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Prognostic Factors ◽  
Public Awareness ◽  
Signs And Symptoms ◽  
Factual Knowledge ◽  
Screening Methods ◽  
Undergraduate Medical Students ◽  
Dietary Risk Factors ◽  
Dietary Risk

Objective: Colorectal cancer (CRC) is one of the top ranked cancers in Oman and the incidences of CRC have been dramatically increasing in recent times. The aim of the study was to assess the level of knowledge of CRC and to understand the level of awareness on CRC screening methods among undergraduate medical students.Material and Methods: This was a cross-sectional study conducted in College of Medicine and Health Sciences, Oman among the undergraduate medical students. The study was a survey based on a questionnaire consisting of 27 items that addressed general risk factors, dietary risk factors, signs and symptoms, screening, and prognostic factors of CRC. Statistical analysis was done using SPSS version 22.Results: A total of three hundred and eighty-two (n=382) students from the premedical (45, 11.8%), preclinical (249, 65.2%) and clinical (88, 23.0%) years participated in the survey. In all the five categories, general risk factors, dietary risk factors, signs and symptoms, screening and prognostic factors, the clinical students had better knowledge and awareness compared to the lower academic year students. Conclusion: There was low level of awareness among the premedical students, and had shown increased level of awareness in subsequent academic years. Undergraduate teachings should focus more on factual knowledge, skills, and screening for colon cancer. Students need to actively participate in public awareness about CRC through community programs in order to boost their knowledge. These initiatives by students can bring about changes in society as well.

Sign in / Sign up

Export Citation Format

Share Document