scholarly journals A Mini Review of Antibacterial Properties of ZnO Nanoparticles

2021 ◽  
Vol 9 ◽  
Author(s):  
Sergey V. Gudkov ◽  
Dmitriy E. Burmistrov ◽  
Dmitriy A. Serov ◽  
Maxim B. Rebezov ◽  
Anastasia A. Semenova ◽  
...  

The development of antibiotic resistance of bacteria is one of the most pressing problems in world health care. One of the promising ways to overcome microbial resistance to antibiotics is the use of metal nanoparticles and their oxides. In particular, numerous studies have shown the high antibacterial potential of zinc oxide nanoparticles (ZnO-NP) in relation to gram-positive and gram-negative bacteria. This mini-review includes an analysis of the results of studies in recent years aimed at studying the antibacterial activity of nanoparticles based on zinc oxide. The dependence of the antibacterial effect on the size of the applied nanoparticles in relation to E. coli and S. aureus is given. The influence of various ways of synthesis of zinc oxide nanoparticles and the main types of modifications of NP-ZnO to increase the antibacterial efficiency are also considered.

2022 ◽  
Vol 12 (2) ◽  
pp. 710
Author(s):  
Fohad Mabood Husain ◽  
Faizan Abul Qais ◽  
Iqbal Ahmad ◽  
Mohammed Jamal Hakeem ◽  
Mohammad Hassan Baig ◽  
...  

Global emergence and persistence of the multidrug-resistant microbes have created a new problem for management of diseases associated with infections. The development of antimicrobial resistance is mainly due to the sub-judicious and unprescribed used of antimicrobials both in healthcare and the environment. Biofilms are important due to their role in microbial infections and hence are considered a novel target in discovery of new antibacterial or antibiofilm agents. In this article, zinc oxide nanoparticles (ZnO-NPs) were prepared using extract of Plumbago zeylanica. ZnO-NPs were characterized and then their antibiofilm activity was tested against Gram-positive and Gram-negative bacteria. The ZnO-NPs were polydispersed, and the average size was obtained as 24.62 nm. The presence of many functional groups indicated that phytocompounds of P. zeylanica were responsible for the synthesis, capping, and stabilization of ZnO-NPs. Synthesized NPs inhibited the biofilm formation of E. coli, S. aureus, and P. aeruginosa by 62.80%, 71.57%, and 77.69%, respectively. Likewise, concentration-dependent inhibition of the EPS production was recorded in all test bacteria. Microscopic examination of the biofilms revealed that ZnO-NPs reduced the bacterial colonization on solid support and altered the architecture of the biofilms. ZnO-NPs also remarkably eradicated the preformed biofilms of the test bacteria up to 52.69%, 59.79%, and 67.22% recorded for E. coli, S. aureus, P. aeruginosa, respectively. The findings reveal the ability of green synthesized zinc oxide nanoparticles to inhibit, as well as eradicate, the biofilms of Gram-positive and Gram-negative bacteria.


2020 ◽  
Vol 32 (10) ◽  
pp. 2589-2593
Author(s):  
Juhi Aggarwal ◽  
Tanveer Alam

Present paper deals with the synthesis of zinc oxide nanoparticles (ZnONPs) using leaf extract of Aristolochia elegans and study of antibacterial property for some human bacterial pathogens. The ZnONPs synthesized were characterized using UV-Vis, FT-IR, XRD, EDX, TEM and SEM techniques. The synthesized ZnONP having a crystallite size of 20.1 nm exhibited a distinct absorption peak maxima at 358 nm. The ZnONPs synthesized using the extract of A. elegans have shown antibacterial activity against M. luteus, S. aureus (Gram-positive), E. coli and P. aeruginosa (Gram-negative).


2021 ◽  
Author(s):  
Fereshteh Shahbazi ◽  
Reza Ahmadi ◽  
Mohammad Noghani ◽  
Gholamreza Karimi

Abstract With the increase in diseases caused by bacterial and viral infections, the need for antibiotics has increased. On the other hand, by creating drug resistance to organicmoietiesbased antibiotics, novel antibiotics have attracted the attention of researchers.Nano-scale metal oxides are increasingly being considered for medical applications, especially as antibacterial agents.In this study, iron oxide nanoparticles (IONPs) and zinc oxide nanoparticles (ZONPs) were prepared via electrical discharge method in liquid medium by changing parameters such as wire diameter and electric current intensity. Synthesized NPs were evaluated by XRD, UV_Visible, FE_SEM, EDS, HR_TEM and TEM analyzes. Also, the antibacterial properties of these nanoparticles were evaluated in different ways against gram-positive and gram-negative bacteria.


2013 ◽  
Vol 52 (25-27) ◽  
pp. 4969-4976 ◽  
Author(s):  
Edris Hoseinzadeh ◽  
Mohammad-Yosef Alikhani ◽  
Mohammad-Reza Samarghandi ◽  
Mehdi Shirzad-Siboni

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6281
Author(s):  
Denis N. Chausov ◽  
Dmitriy E. Burmistrov ◽  
Alexander D. Kurilov ◽  
Nikolay F. Bunkin ◽  
Maxim E. Astashev ◽  
...  

The present study a comprehensive analysis of the antibacterial properties of a composite material based on borosiloxane and zinc oxide nanoparticles (ZnO NPs). The effect of the polymer matrix and ZnO NPs on the generation of reactive oxygen species, hydroxyl radicals, and long-lived oxidized forms of biomolecules has been studied. All variants of the composites significantly inhibited the division of E. coli bacteria and caused them to detach from the substrate. It was revealed that the surfaces of a composite material based on borosiloxane and ZnO NPs do not inhibit the growth and division of mammalians cells. It is shown in the work that the positive effect of the incorporation of ZnO NPs into borosiloxane can reach 100% or more, provided that the viscoelastic properties of borosiloxane with nanoparticles are retained.


2018 ◽  
Vol 121 ◽  
pp. 224-231 ◽  
Author(s):  
Muthuchamy Maruthupandy ◽  
Govindan Rajivgandhi ◽  
Thillaichidambaram Muneeswaran ◽  
Ji-Ming Song ◽  
Natesan Manoharan

RSC Advances ◽  
2015 ◽  
Vol 5 (12) ◽  
pp. 8806-8813 ◽  
Author(s):  
Ekrem Ozkan ◽  
Feyza Tunali Ozkan ◽  
Elaine Allan ◽  
Ivan P. Parkin

Crystal violet–ZnO mixtures were incorporated into PDMS by a simple two step method. The modified polymer demonstrated significant antibacterial activity againstE. coliandS. aureus, showing possibly the most potent light-induced antibacterial polymer reported to date.


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