scholarly journals Aestivation Induces Changes in the mRNA Expression Levels and Protein Abundance of Two Isoforms of Urea Transporters in the Gills of the African Lungfish, Protopterus annectens

2017 ◽  
Vol 8 ◽  
Author(s):  
You R. Chng ◽  
Jasmine L. Y. Ong ◽  
Biyun Ching ◽  
Xiu L. Chen ◽  
Kum C. Hiong ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Protein Abundance ◽  
Expression Levels ◽  
Protopterus Annectens ◽  
African Lungfish ◽  
Mrna Expression Levels

Comparing mRNA expression levels to protein abundance inMagnolia denudatapollen following cryopreservation

2019 ◽  
pp. 113-118
Author(s):  
J. Xu ◽  
Y. Liu ◽  
B.L. Li ◽  
Q. Liu ◽  
Y. Shi ◽  
...  
Keyword(s):  
Mrna Expression ◽  
Protein Abundance ◽  
Expression Levels ◽  
Mrna Expression Levels

scholarly journals The role of CXCR3 and its ligands expression in Brucellar spondylitis

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Xin Hu ◽  
Xiaoqian Shang ◽  
Liang Wang ◽  
Jiahui Fan ◽  
Yue Wang ◽  
...  
Keyword(s):  
Protein Expression ◽  
Mrna Expression ◽  
Mononuclear Cells ◽  
Healthy Controls ◽  
Inflammatory Infiltration ◽  
Peripheral Blood Mononuclear ◽  
Expression Levels ◽  
Inflammatory Damage ◽  
Ifn Γ ◽  
Mrna Expression Levels

Abstract Aim Brucellar spondylitis (BS) is one of the most serious complications of brucellosis. CXCR3 is closely related to the severity of disease infection. This research aimed to study the degree of BS inflammatory damage through analyzing the expression levels of CXCR3 and its ligands (CXCL9 and CXCL10) in patients with BS. Methods A total of 29 BS patients and 15 healthy controls were enrolled. Real-Time PCR was used to detect the mRNA expression levels of IFN-γ, CXCR3, CXCL9 and CXCL10 in peripheral blood mononuclear cells (PBMCs) of BS patients and healthy controls. Hematoxylin-Eosin staining was used to show the pathological changes in BS lesion tissues. Immunohistochemistry staining was used to show the protein expression levels of Brucella-Ab, IFN-γ, CXCR3, CXCL9 and CXCL10 in BS lesion tissues. At the same time, ELISA was used to detect the serum levels of IFN-γ, CXCL9 CXCL10 and autoantibodies against CXCR3 in patients with BS. Results In lesion tissue of BS patients, it showed necrosis of cartilage, acute or chronic inflammatory infiltration. Brucella-Ab protein was abundantly expressed in close lesion tissue. And the protein expression levels of IFN-γ, CXCR3 and CXCL10 were highly expressed in close lesion tissue and serum of BS patients. At the same time, the mRNA expression levels of IFN-γ, CXCR3 and CXCL10 in PBMCs of BS patients were significantly higher than those in controls. Conclusion In our research, the expression levels of IFN-γ, CXCR3 and its ligands were significantly higher than those in controls. It suggested that high expression levels of IFN-γ, CXCR3 and its ligands indicated a serious inflammatory damage in patients with BS.

scholarly journals Altered mRNA expression levels of autophagy- and apoptosis-related genes in the FOXO pathway in schizophrenia patients treated with olanzapine

2021 ◽  
Vol 746 ◽  
pp. 135669
Author(s):  
Shuguang Gu ◽  
Fengwei Cui ◽  
Jiajun Yin ◽  
Chunxia Fang ◽  
Liang Liu
Keyword(s):  
Mrna Expression ◽  
Expression Levels ◽  
Mrna Expression Levels
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