scholarly journals Global Oral Health Policies and Guidelines: Using Silver Diamine Fluoride for Caries Control

2021 ◽  
Vol 2 ◽  
Author(s):  
Sherry Shiqian Gao ◽  
Gwendolyn Amarquaye ◽  
Peter Arrow ◽  
Kalpana Bansal ◽  
Raman Bedi ◽  
...  

Silver diamine fluoride (SDF) was developed in Japan in the 1960s. It is a clear solution containing silver and fluoride ions. Because of its anti-bacterial and remineralizing effect, silver diamine fluoride has been used in managing dental caries for decades worldwide. This paper aims to summarize and discuss the global policies, guidelines, and relevant information on utilizing SDF for caries management. SDF can be used for treating dental caries in most countries. However, it is not permitted to be used in mainland China. Several manufacturers, mainly in Australia, Brazil, India, Japan, and the United States, produce SDF at different concentrations that are commercially available around the world. The prices differ between contents and brands. Different government organizations and dental associations have developed guidelines for clinical use of SDF. Dental professionals can refer to the specific guidelines in their own countries or territories. Training for using SDF is part of undergraduate and/or postgraduate curriculums in almost all countries. However, real utilization of SDF of dentists, especially in the private sector, remains unclear in most places because little research has been conducted. There are at least two ongoing regional-wide large-scale oral health programs, using SDF as one of the components to manage dental caries in young children (one in Hong Kong and one in Mongolia). Because SDF treatment does not require caries removal, and it is simple, non-invasive, and inexpensive, SDF is a valuable strategy for caries management in young children, elderly people, and patients with special needs. In addition, to reduce the risk of bacteria or virus transmission in dental settings, using SDF as a non-aerosol producing procedure should be emphasized under the COVID-19 outbreak.

2017 ◽  
Author(s):  
Jeremy A Horst ◽  
Jong Seto

ABSTRACTThe current paradigm of treatment for dental caries (tooth decay) in primary teeth is dangerous, fails to reach many children, and suffers high recurrence. Acceptance of the paradigm arises from a misperception that untreated caries in primary teeth is a threat to life. We show a linear relationship between age and deaths in the United States from 1999 through 2015 caused by dental caries, pulpal / periapical abscess, or facial cellulitis. The intercept of 6 years coincides with emergence of the first permanent tooth: it appears that caries in primary teeth is not a threat to life. Thus, treatment goals should be to avoid pain, which is not possible with operative dentistry, as it causes pain. Medical management of caries is a distinct treatment philosophy which employs topical minimally invasive therapies that treat the disease, and is not merely prevention. Silver diamine fluoride (SDF) is a central agent to enable effective non-invasive treatment. The announcement of FDA Breakthrough Therapy designation suggests that SDF will become the first FDA approved drug for treating the disease dental caries. Since our last review, 4 clinical trials have been completed, which inform an update to the application protocol and frequency regimen. Suggestions from these studies are to skip the rinsing step due to demonstration of safety and concern of diminished effectiveness by dilution, and to start patients with an intensive regimen of multiple applications over the first few weeks. Breakthroughs in elucidating the impact of SDF on tooth structure and the plaque microbiome inform potential opportunities for bioengineering and understanding caries arrest, respectively. Dentists have been surprised by preference of this treatment over traditional invasive approaches. Renewed interest in this old material has delivered progress to optimize the judicious use of SDF, and enable a revolution in caries management – particularly for primary teeth.ONE SENTENCE SUMMARYAnesthesia is inappropriate for first-line treatment of early childhood caries now that safe topical treatments such as silver diamine fluoride are available.


2021 ◽  
Author(s):  
Ryan Richard Ruff ◽  
Rachel Whittemore ◽  
Martyna Grochecki ◽  
Jillian Bateson ◽  
Tamarinda Barry-Godin

Objectives: Silver diamine fluoride (SDF) is an effective non-surgical treatment for dental caries which may also impact oral health-related quality of life (OHRQoL). The objective of this study was to conduct a network meta-analysis of SDF versus other standard of care therapies on OHRQoL. Methods: Studies comparing SDF to an acceptable comparator and included a quantitatively-evaluated oral health-related quality of life measure were reviewed for eligibility and analyzed using network meta-analysis. Studies were also assessed for risk of bias and quality of evidence. Results: Following screening, ten studies were evaluated for full-text eligibility and five were retained for meta-analyses. Studies included in quantitative synthesis were classified as a high degree of evidence, suggesting estimated effects are similar to true effects. Direct and indirect estimates from network meta-analysis indicated that OHRQoL in children was not significantly different when treated with SDF versus atraumatic restorations (d = 0.02, 95% CI = -0.32, 0.36) or placebo (d = 0.03, 95% CI = -0.16, 0.22). Conclusions: Evidence from the literature consistently shows no discernible impact on OHRQoL across various non-surgical treatments for dental caries. Overall oral health-related quality of life may increase regardless of treatment protocol due to treatment of the underlying disease. Concerns over the staining of dental decay and oral mucosa resulting from treatment with silver diamine fluoride do not seem to affect OHRQoL.


2021 ◽  
Author(s):  
Ryan Richard Ruff ◽  
Tamarinda J Barry Godin ◽  
Topaz Murray Small ◽  
Richard Niederman

Objective: Silver diamine fluoride (SDF) is a non-surgical treatment for the arrest and prevention of dental caries that results in irreversible black staining of dental decay. The objective of this study was to evaluate the impact of SDF treatment on oral health-related quality of life (OHRQoL) relative to a standard package of glass ionomer sealants and atraumatic restorative treatment. Methods: CariedAway is a pragmatic, longitudinal, cluster-randomized non- inferiority trial of non-surgical interventions for caries. Secondary study outcomes included OHRQoL and academic performance. Oral health-related quality of life was measured at each study visit using the Child Oral Health Impact Profile. Change in OHRQoL was assessed using linear regression and non-inferiority was determined using t-tests. Results: Untreated decay at baseline was associated with signifcantly worse ORHQoL and treatment in both groups resulted in incremental improvement. Quality of life in children receiving silver diamine fluoride was non-inferior to those receiving sealants and ART at least six months post-treatment. Additionally, change in OHRQoL did not depend on the severity of baseline decay. Conclusions: ORHQoL is related to untreated dental caries, however no appreciable change was observed following SDF treatment relative to standard preventive therapies.


2011 ◽  
Vol 35 (2) ◽  
pp. 98
Author(s):  
Lendrawati Lendrawati

AbstrakKaries merupakan masalah kesehatan gigi yang banyak diderita oleh anak-anak seluruh dunia terutama negara berkembang termasuk Indonesia. Kerusakan gigi pada anak-anak terjadi lebih cepat dibandingkan orang dewasa karena gigi yang baru erupsi masih dalam proses maturasi dan proses mineralisasi belum sempurna. Tubuli dentin anak anak yang masih lebar menyebabkan pembentukan jaringan sklerotik tidak sempurna dan buffer saliva masih kurang sehingga aktivitas proteolitik menjadi lebih banyak di dalam mulut. Fluor merupakan zat mineral yang digunakan sebagai bahan yang efektif mencegah terjadinya karies gigi dapat membuat lapisan email tahan terhadap kerusakan yang disebabkan pelarutan email oleh zat asam. Strategi pencegahan karies lebih efektif sejak diperkenalkannya silver diamina fluoride (SDF) yang merupakan cairan tidak berwarna mengandung ion fluoride yang digunakan untuk memacu terjadinya proses remineralisasi hidoksiapatit mineral gigi. Penggunaan SDF ini merupakan metoda Arresting Caries Treatment (ACT). SDF menggabungkan efek penguatan gigi dari natrium fluoride (NaF) dan efek nitrat perak.Konsentrasi efektif solusi SDF 38% (44.800 ion fluoride ppm) digunakan untuk menghambat perkembangan karies pada gigi sulung anak-anak, terutama anak-anak yang sulit untuk dilakukan perawatan. SDF sederhana, mudah dalam mengaplikasikan dan biaya pemakaian lebih murah. SDF merupakan bahan yang tepat untuk digunakan untuk mengatasi masalah kesehatan gigi masyarakat terutama pada anak-anak.Kata Kunci : karies gigi, silver diamine fluoride, Arresting Caries Treatment, topikalAbstractDental caries is a health problem that affects many children all over the world, especially in developing countries, including Indonesia. Tooth decay in children occurs more rapidly than adults because the new tooth eruption is still in the process of maturation and mineralization process is not perfect. Dentin tubules of children is still wide lead sclerotic tissue formation was not perfect and still less saliva buffer so that a more proteolytic activity in the mouth. Fluor is a mineral substance that used as an ingredient that effectively prevent the occurrence of dental caries and can make enamel resistant to decay caused by acid dissolution email. TINJAUAN PUSTAKA99Strategy of caries prevention is more effective since the introduction of silver diamine fluoride (SDF) which is a colorless liquid containing fluoride ions are used to induce the process of remineralization mineral of tooth that is hidoksiapatit. SDF is a method of Arresting Caries Treatment (ACT). That combines the strengthening tooth effects of sodium fluoride (NaF) and the effect of nitrate perak. Used of 38% concentration of SDF solution (44,800 ppm fluoride ion) are effective to inhibit the development of caries in primary teeth of children, especially children who are difficult to be treated. SDF use is simple, easy to apply and use costs cheaper. SDF is a good material to be used in the public dental health problems, especially in children.Key word : dental caries, silver diamine fluoride, Arresting Caries Treatment, topical


2021 ◽  
Author(s):  
Ketian Wang ◽  
Gillian Hiu Man Lee ◽  
Pei Liu ◽  
Xiaoli Gao ◽  
Samuel Yeung Shan Wong ◽  
...  

Abstract Background: It has been recognized that oral health education for parents is critical for preventing early childhood caries (ECC). Few parents practiced caries prevention procedures for their children in daily life, though. A novel intervention scheme using mobile messages will be developed in this study under the framework of the Health Belief Model (HBM). The objective of the present randomized clinical trial (RCT) is to evaluate the effectiveness of the new scheme in promoting oral health of young children by reducing dental caries.Methods: This RCT will involve 26-36 child care centers or kindergartens with nursery classes (clusters) located in Hong Kong. A total of 518-628 child-parent dyads (child age: 18-30 months) will be recruited and randomly allocated at the cluster level into the test or control group with a 1:1 ratio. For parents in the test group, the intervention will consist of a set of HBM-based text messages sent regularly in 48 weeks. A standard text message will be sent to the parents in the control group in the first week. The primary outcome will be dental caries measured by dmft/dmfs of the children after 2 years (around 4 years of age). The secondary outcomes will be toothbtushing and sugar intakes. Discussion: HBM-based intervention via a low-cost text messaging vehicle may serves as a viable way to empower parents to establish proper oral health behaviors for their children and safeguard the oral health of children in Hong Kong.Trial registration: This study has been registered on ClinicalTrials.gov (ID: NCT04665219).


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Syed Saad B. Qasim ◽  
Dena Ali ◽  
Abdul Samad Khan ◽  
Shafiq Ur Rehman ◽  
Abid Iqbal ◽  
...  

Background. This bibliometric analysis is aimed at reviewing the research pattern on the use of silver diamine fluoride (SDF) in dentistry using various citation metrics. Methods. A well-curated search was conducted on Elsevier’s Scopus database for the relevant literature on SDF published between 1969 and 2021. Bibliographic information such as information related to citations, bibliographic data, abstracts, keywords, and other relevant information was extracted using different combinations of keywords (“silver diamine fluoride” OR “Silver Diamine Fluorides” OR “Diamine Fluoride” OR “Silver Fluoride”). Analysis and visualization of the selected documents and related data were performed using various tools and software including MS Excel, MS Access, Bibexcel, VOS viewer, Biblioshiny, and Gephi. VOS Viewer was utilized for the Graph Modeling Language (GML) to generate graphical representations of the data. Furthermore, network graphs were generated to assess the various associations between research themes, countries, organizations, authors, journals, and citations. Results. The initial search yielded 662 documents, of which 410 were chosen for analysis. 252 records were deemed irrelevant. The chosen records consisted of journal articles ( n = 351 ), conference papers ( n = 14 ), book chapters ( n = 1 ), and review articles ( n = 44 ). The results showed that there was an upward trend in the research on SDF, and a substantial increase was observed in the citation index after 2014. Researchers from the United States of America, Hong Kong, and Japan were the top contributors, with organizations and authors from the Faculty of Dentistry, University of Hong Kong, leading the way in citations and productivity. Conclusion. The bibliometric analysis provides valuable information regarding the total number of publications on SDF and their citation details. It also identifies the leading countries and organizations involved in the research on SDF and provides a comprehensive analysis of the research trends related to SDF.


2021 ◽  
pp. 155633162110013
Author(s):  
Joseph D. Lamplot ◽  
Ajay Premkumar ◽  
Evan W. James ◽  
Cort D. Lawton ◽  
Andrew D. Pearle

Introduction: Opioid misuse and overprescription have contributed to a national public health crisis in the United States. Postoperatively, patients are often left with unused opioids, which pose a risk for diversion if not appropriately disposed of. Patients are infrequently provided instructions on safe disposal methods of surplus opioids. Purpose: We sought to determine the current rates of disposal of unused opioids and the reported disposal mechanisms for unused opioids that were prescribed for acute postoperative pain control. Methods: A systematic review was performed of the PubMed, Cochrane, and Embase databases for relevant articles from their earliest entries through October 2, 2019. We used the search terms “opioid” or “narcotic” and “disposal” and “surgery.” Studies were considered for inclusion if they reported the rate of disposal of unused opioids following surgery. A screening strategy was used to identify relevant articles using Covidence. For studies meeting inclusion criteria, relevant information was extracted. Results: Sixteen studies met inclusion criteria. We found that surplus opioid disposal rates varied widely, from 4.9% to 87.0%. Among studies with no intervention (opioid disposal education or drug disposal kit/bag), rates of opioid disposal ranged from 4.9% to 46.5%. While 7 studies used opioid disposal education as an intervention, only 3 showed a significant increase in surplus opioid disposal compared with standard care. All 3 studies that used an opioid disposal kit or bag as an intervention demonstrated significant increases in opioid disposal. Conclusions: Baseline rates of surplus opioid disposal are relatively low in the postoperative setting. Our findings suggest that opioid disposal kits significantly increase rates of surplus opioid disposal postoperatively. Further research, including a large-scale cost-benefit analysis, will be necessary prior to recommending widespread implementation of drug disposal kits or bags.


2020 ◽  
Vol 99 (8) ◽  
pp. 891-897 ◽  
Author(s):  
A.M. Kranz ◽  
R.G. Rozier ◽  
B.D. Stein ◽  
A.W. Dick

In the United States, state Medicaid programs pay for medical and dental care for children from low-income families and support nondental primary care providers delivering preventive oral health services (POHS) to young children in medical offices (“medical POHS”). Despite the potential of these policies to expand access to care, there is concern that they may replace dental visits with medical POHS. Using Medicaid claims from 38 states from 2006 to 2014, we conducted a repeated cross-sectional study and used linear probability regression to estimate the association between the annual proportion of children in a county receiving medical POHS and the probability that a child received 1) dental POHS and 2) a dental visit in a given year. Models included county and year fixed effects and controlled for child- and county-level factors, and standard errors were clustered at the state level. In a weighted population of 45.1 million child-years (age, 6 mo to <6 y), we found no significant nor substantively important association between the proportion of children in a county receiving medical POHS and the probability that a child received dental POHS or a dental visit. Additionally, we found an almost zero probability (<0.001) that the reduction in dental POHS was at least as large as the expansion in medical POHS (full substitution) and a 0.50 probability that increased medical POHS was associated with an increase in dental POHS of at least 6.6% of the expansion of medical POHS. Results were similar when receipt of dental visits was examined. This study failed to find evidence that medical POHS replaced dental visits for young children enrolled in Medicaid and, in fact, offers evidence that increased medical POHS was associated with increased utilization of dental care. Given lower-than-desired rates of dental visits for this population, delivery of medical POHS should be expanded.


2018 ◽  
Vol 52 (5) ◽  
pp. 387-391 ◽  
Author(s):  
Vita Machiulskiene ◽  
Joana Christina Carvalho

Classifications employed to measure dental caries should first of all reflect the dynamics of the disease, in order to provide a solid basis for subsequent treatment decisions and for further monitoring of dental health of individual patients and populations. The contemporary philosophy of dental caries management implies that nonoperative treatment of caries lesions should be implemented whenever possible, limiting operative interventions to the severe and irreversible cases. The ORCA Saturday Afternoon Symposium 2016, held back-to-back to the 63rd ORCA Congress in Athens, Greece, was intended to provide an update on general requirements for clinical caries diagnosis and to overview caries diagnostic classifications including their rationale, validation, advantages, and limitations. Clinical caries diagnostic criteria and caries management outcomes are interrelated, and any diagnostic classification disregarding this concept is outdated, according to the current understanding of oral health care. Choosing clinical caries diagnostic classifications that assess the activity status of detected lesions should be a priority for dental professionals since these classifications favor the best clinical practice directed towards nonoperative interventions. The choice of clinical caries diagnostic classifications in research, in clinical practice, and in public health services should be guided by the best available scientific evidence. The clinical caries diagnostic classifications should be universally applicable in all these fields. Policy making in oral health care and the underlying policy analyses should follow the same standards. Any clinical caries diagnostic classification disregarding the universality of its use is of limited or no interest in the context of the clinical caries diagnosis of today.


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