scholarly journals On the Impacts of Ions of Ionospheric Origin and Their Composition on Magnetospheric EMIC Waves

2021 ◽  
Vol 8 ◽  
Author(s):  
Justin H. Lee ◽  
Lauren W. Blum ◽  
Lunjin Chen
Keyword(s):  
Wave Generation ◽  
Magnetospheric Plasma ◽  
Large Numbers ◽  
Emic Wave ◽  
Direct Measurements ◽  
Ion Cyclotron ◽  
Earth's Magnetosphere ◽  
Ion Species ◽  
Emic Waves

Large numbers of theory and observation studies have been conducted on electromagnetic ion cyclotron (EMIC) waves occurring in Earth’s magnetosphere. Numerous studies have shown that accurately specifying the ions of ionospheric origin and their composition can greatly improve understanding of magnetospheric EMIC waves, specifically their generation, their properties, and their effects on the magnetospheric plasma populations. With the launch and operations of multiple recent missions carrying plasma instrumentation capable of acquiring direct measurements of multiple ion species, we use this opportunity to review recent magnetospheric EMIC wave efforts utilizing these new assets, with particular focus on the role of ions of ionospheric origin in wave generation, propagation, and interaction with particles. The review of progress leads us to a discussion of the unresolved questions to be investigated using future modeling capabilities or when new missions or instrumentation capabilities are developed.

Direct measurements of cold and hot plasma composition and EMIC waves in the outer magnetosphere: Implications for inner magnetosphere wave-particle interactions

2021 ◽  
Author(s):  
Justin Lee ◽  
Drew Turner ◽  
Sarah Vines ◽  
Robert Allen ◽  
Sergio Toledo-Redondo
Keyword(s):  
Unstable Wave ◽  
Linear Wave ◽  
Plasma Composition ◽  
Inner Magnetosphere ◽  
Hot Plasma ◽  
Emic Wave ◽  
Direct Measurements ◽  
Wave Numbers ◽  
Emic Waves

<p>Although thorough characterization of magnetospheric ion composition is rare for EMIC wave studies, convective processes that occur more frequently in Earth’s outer magnetosphere have allowed the Magnetospheric Multiscale (MMS) satellites to make direct measurements of the cold and hot plasma composition during EMIC wave activity. We will present an observation and linear wave modeling case study conducted on EMIC waves observed during a perturbed activity period in the outer dusk-side magnetosphere. During the two intervals investigated for the case study, the MMS satellites made direct measurements of cold plasmaspheric plasma in addition to multiple hot ion components at the same time as EMIC wave emissions were observed. Applying the in-situ plasma composition data to wave modeling, we find that wave growth rate is impacted by the complex interactions between the cold as well as the hot ion components and ambient plasma conditions. In addition, we observe that linear wave properties (unstable wave numbers and band structure) can significantly evolve with changes in cold and hot ion composition. Although the modeling showed the presence of dense cold ions can broaden the range of unstable wave numbers, consistent with previous work, the hot heavy ions that were more abundant nearer storm main phase could limit the growth of EMIC waves to smaller wave numbers. In the inner magnetosphere, where higher cold ion density is expected, the ring current heavy ions could also be more intense near storm-time, possibly resulting in conditions that limit the interactions of EMIC waves with trapped radiation belt electrons to multi-MeV energies. Additional investigation when direct measurements of cold and hot plasma composition are available could improve understanding of EMIC waves and their interactions with trapped energetic particles in the inner magnetosphere.</p>

Modulation of Ion Pitch Angle in the Presence of Large-amplitude, Electromagnetic Ion Cyclotron (EMIC) Waves: 1-D Hybrid Simulation

2021 ◽  
Author(s):  
Shuo Ti ◽  
Tao Chen ◽  
Jiansheng Yao
Keyword(s):  
Large Amplitude ◽  
Pitch Angle ◽  
Hybrid Simulation ◽  
Bulk Velocity ◽  
Ion Energy ◽  
Ion Cyclotron ◽  
Angle Modulation ◽  
Wave Normal ◽  
Ion Species ◽  
Emic Waves

<p>Large-amplitude electromagnetic ion cyclotron (EMIC) waves induce unique dynamics of charged particle movement in the magnetosphere. In a recent study, modulation of the ion pitch angle in the presence of large-amplitude EMIC waves is observed, and there lacks a good explanation for this phenomenon. We investigate this modulation primarily via a 1-D hybrid simulation model and find that the modulation is caused by the bulk velocity triggered by large-amplitude EMIC waves. Affected by the bulk velocity, the number density of ions will enhance around pitch angle . Beyond that, the ion pitch angle is also modulated by the EMIC waves, and the modulation period is half of the EMIC waves' period. In addition, parameters that affect ion pitch angle modulation, including the wave amplitude, ion energy, ion species, and wave normal angle, are studied in our work.</p>

scholarly journals Nonlinear compressional electromagnetic ion-cyclotron wavepackets in space plasmas

2005 ◽  
Vol 12 (4) ◽  
pp. 441-450 ◽  
Author(s):  
I. Kourakis ◽  
P. K. Shukla
Keyword(s):  
Space Plasmas ◽  
Circularly Polarized ◽  
Envelope Solitons ◽  
Emic Wave ◽  
Ion Acoustic ◽  
Ion Cyclotron ◽  
Density Perturbations ◽  
Parametric Coupling ◽  
Cubic Nonlinear Schrödinger Equation ◽  
Emic Waves

Abstract. The parametric coupling between large amplitude magnetic field-aligned circularly polarized electromagnetic ion-cyclotron (EMIC) waves and ponderomotively driven ion-acoustic perturbations in magnetized space plasmas is considered. A cubic nonlinear Schrödinger equation for the modulated EMIC wave envelope is derived, and then solved analytically. The modulated EMIC waves are found to be stable (unstable) against ion-acoustic density perturbations, in the subsonic (supersonic, respectively) case, and they may propagate as "supersonic bright" (`"subsonic dark", i.e. "black" or "grey")type envelope solitons, i.e. electric field pulses (holes, voids),associated with (co-propagating) density humps. Explicit bright and dark (black/grey) envelope excitation profiles are presented, and the relevance of our investigation to space plasmas is discussed.

Localization of Intracisternal a Particle Antigens in Neoplastic Cells and Preimplantation Mouse Embryos

1980 ◽  
Vol 38 ◽  
pp. 696-697
Author(s):  
Thomas T.F. Huang ◽  
Patricia G. Calarco
Keyword(s):  
Endoplasmic Reticulum ◽  
Normal Development ◽  
Mouse Embryos ◽  
Neoplastic Cells ◽  
Large Numbers ◽  
Preimplantation Mouse Embryos ◽  
Preimplantation Mouse ◽  
Intracisternal A Particle ◽  
Normal Feature

The stage specific appearance of a retravirus, termed the Intracisternal A particle (IAP) is a normal feature of early preimplantation development. To date, all feral and laboratory strains of Mus musculus and even Asian species such as Mus cervicolor and Mus pahari express the particles during the 2-8 cell stages. IAP form by budding into the endoplasmic reticulum and appear singly or as groups of donut-shaped particles within the cisternae (fig. 1). IAP are also produced in large numbers in several neoplastic cells such as certain plasmacytomas and rhabdomyosarcomas. The role of IAP, either in normal development or in neoplastic behavior, is unknown.

scholarly journals Characterizing Highly Benefited Patients in Randomized Clinical Trials

2017 ◽  
Vol 13 (1) ◽  
Author(s):  
Vivek Charu ◽  
Paul B. Rosenberg ◽  
Lon S. Schneider ◽  
Lea T. Drye ◽  
Lisa Rein ◽  
...  
Keyword(s):  
Randomized Clinical Trials ◽  
Controlled Trial ◽  
New Method ◽  
Usual Model ◽  
Randomized Controlled ◽  
Working Model ◽  
Large Numbers ◽  
High Benefit ◽  
Two Stages

AbstractPhysicians and patients may choose a certain treatment only if it is predicted to have a large effect for the profile of that patient. We consider randomized controlled trials in which the clinical goal is to identify as many patients as possible that can highly benefit from the treatment. This is challenging with large numbers of covariate profiles, first, because the theoretical, exact method is not feasible, and, second, because usual model-based methods typically give incorrect results. Better, more recent methods use a two-stage approach, where a first stage estimates a working model to produce a scalar predictor of the treatment effect for each covariate profile; and a second stage estimates empirically a high-benefit group based on the first-stage predictor. The problem with these methods is that each of the two stages is usually agnostic about the role of the other one in addressing the clinical goal. We propose a method that characterizes highly benefited patients by linking model estimation directly to the particular clinical goal. It is shown that the new method has the following two key properties in comparison with existing approaches: first, the meaning of the solution with regard to the clinical goal is the same, and second, the value of the solution is the best that can be achieved when using the working model as a predictor, even if that model is incorrect. In the Citalopram for Agitation in Alzheimer’s Disease (CitAD) randomized controlled trial, the new method identifies substantially larger groups of highly benefited patients, many of whom are missed by the standard method.

Beta-Blocker Attenuates Cardiotoxicity Related Anthracycline Usage

2021 ◽  
Vol 104 (8) ◽  
pp. 1389-1392
Keyword(s):  
Side Effects ◽  
Cancer Therapy ◽  
Mortality Rate ◽  
Cancer Patients ◽  
Beta Blocker ◽  
The Other ◽  
Large Numbers ◽  
Therapy Effectiveness ◽  
Chemotherapy Agents

To summarize the recent trials and studies of the role of beta-blocker on the treatment for cancer patients treated with anthracycline to decrease morbidity and mortality rate. Good management of cancer will result in large numbers of cancer survivors. On the other hand, cancer therapy also has side effects, one of which is cardiotoxicity. Cardiotoxicity could reduce therapy effectiveness, hence, increase disease progression and mortality rate. Anthracyclines is one of the chemotherapy agents with cardiotoxicity as a side effect. Beta-blocker has the ability to reduce cardiotoxicity due to anthracyclines usage. Keywords: Beta-blocker; Cardiotoxicity; Anthracyclines

scholarly journals Three-dimensional multispecies hybrid simulation of Titan's highly variable plasma environment

2007 ◽  
Vol 25 (1) ◽  
pp. 117-144 ◽  
Author(s):  
S. Simon ◽  
A. Boesswetter ◽  
T. Bagdonat ◽  
U. Motschmann ◽  
J. Schuele
Keyword(s):  
Plasma Flow ◽  
Flow Direction ◽  
Three Dimensional ◽  
Hybrid Simulation ◽  
Slight Modification ◽  
Magnetospheric Plasma ◽  
Particle Model ◽  
Tail Region ◽  
Simulation Code ◽  
Ion Species

Abstract. The interaction between Titan's ionosphere and the Saturnian magnetospheric plasma flow has been studied by means of a three-dimensional (3-D) hybrid simulation code. In the hybrid model, the electrons form a mass-less, charge-neutralizing fluid, whereas a completely kinetic approach is retained to describe ion dynamics. The model includes up to three ionospheric and two magnetospheric ion species. The interaction gives rise to a pronounced magnetic draping pattern and an ionospheric tail that is highly asymmetric with respect to the direction of the convective electric field. Due to the dependence of the ion gyroradii on the ion mass, ions of different masses become spatially dispersed in the tail region. Therefore, Titan's ionospheric tail may be considered a mass-spectrometer, allowing to distinguish between ion species of different masses. The kinetic nature of this effect is emphasized by comparing the simulation with the results obtained from a simple analytical test-particle model of the pick-up process. Besides, the results clearly illustrate the necessity of taking into account the multi-species nature of the magnetospheric plasma flow in the vicinity of Titan. On the one hand, heavy magnetospheric particles, such as atomic Nitrogen or Oxygen, experience only a slight modification of their flow pattern. On the other hand, light ionospheric ions, e.g. atomic Hydrogen, are clearly deflected around the obstacle, yielding a widening of the magnetic draping pattern perpendicular to the flow direction. The simulation results clearly indicate that the nature of this interaction process, especially the formation of sharply pronounced plasma boundaries in the vicinity of Titan, is extremely sensitive to both the temperature of the magnetospheric ions and the orientation of Titan's dayside ionosphere with respect to the corotating magnetospheric plasma flow.

The Role of Fluid Flow Phenomena in the Czochralski Growth of Oxides.

1981 ◽  
Vol 9 ◽  
Author(s):  
D.C. Miller
Keyword(s):  
Fluid Flow ◽  
Defect Density ◽  
Major Effect ◽  
Czochralski Growth ◽  
Simulation Experiments ◽  
Direct Measurements ◽  
Flow Geometry ◽  
Flow Phenomena

ABSTRACTIn the Czochralski growth of single crystals from large melts, fluid flow phenomena have a major effect on interface shape, growth striations, defect density and the length of crystals which can be grown from a melt of given volume and thermal geometry. Because of the technical difficulties encountered in making direct measurements in molten oxides, simulation experiments have been extensively utilized to gain insight into melt behavior.Both temperature profile and flow geometry results from simulation experiments are discussed. This data is supported by direct melt observations and results from the characterization of grown crystals. When reviewed together, this information offers new insights into the complex behavior of Czochralski growth processes, including the role of thermal gradients, crystal rotation, and surface tension driven (Marangoni) convection.

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