Samskara is defined as a process of bringing about a desired modification or establishing a change of property in a drug or group of drugs. In the process of Aushadhi Nirmana, varied number of procedures (Samskaras) are adopted to inculcate the desired dosage form and efficacy to the medicine. Among all Samskaras, Kaala plays a vital role in Ayurvedic pharmaceutics. Kaala is a constant factor which follows incoherently in every step of Aushadhi Nirmana. Active principles of plants vary in every season and at different quarters of the day. After the collection of drugs for a pharmaceutical preparation, Kaala plays its role during Paka of various formulations. The definition of pharmaceutics does not end with mere production of a dosage form but also includes its safety and efficacy. Kaala has the potential to influence both these factors. Thus, our Acharyas have provided meticulous information on Ayurvedic pharmaceutics giving prime importance to a minute, yet very significant aspect called “Kaala”.
Indirect Colorimetric Estimation of Fluoride Ion in Water and Pharmaceutical Preparation Samples