scholarly journals Rare Generalized Form of Fungal Dermatitis in a Horse: Case Report

Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 871
Author(s):  
Barbara Padalino ◽  
Jeanine Rhoda Sandy ◽  
Roberta Barrasso ◽  
Adriana Trotta ◽  
Giancarlo Bozzo ◽  
...  
Keyword(s):  
Diagnostic Procedures ◽  
Geotrichum Candidum ◽  
Skin Lesions ◽  
Blood Analysis ◽  
Appropriate Treatment ◽  
Allergic Skin ◽  
Mild Leucocytosis ◽  
Head Neck

A rare case of Geotrichum spp. dermatitis in a horse is presented. After unrelated, previous surgery and antibiotic treatment, a saddle horse showed well-circumscribed areas of non-pruritic alopecia. Suspecting allergic skin disease, the horse was treated with corticosteroids. The skin lesion spread, and a second veterinarian was consulted. At clinical examination, the horse was lethargic, pyretic and hair was shedding/easily epilated over the head, neck, shoulders, and legs and the hind legs were swollen. Blood analysis revealed mild leucocytosis and hyperglobulinemia. Hair, skin scraping, and skin biopsy ruled out parasites and bacteria; cytology identified yeast-like structures with hyphae or pseudohyphae. Geotrichum candidum was isolated on culture. Treatment consisted of stable disinfection, topical application of an antifungal solution, vitamins C and E supplementation and allowing the horse to graze in sunlight for at least 6 h/day. At 3-weeks follow-up, the horse had gained weight, alopecia was decreased, and all other clinical parameters were normal. Antifungal treatment was continued twice a week for three months. This study suggests Geotrichum candidum may cause skin lesions in horses after long-term use of corticosteroids or antibiotics. To avoid unnecessary and prolonged suffering in cases of dermatitis, veterinarians should be promptly consulted, appropriate diagnostic procedures conducted, so that a definitive diagnosis can be reached, and an appropriate treatment regimen implemented.

scholarly journals Juvenile Aggressive Trabecular Ossifying Fibroma of Mandible: A Rare Case Report

2016 ◽  
Vol 6 (1) ◽  
pp. 45-51
Author(s):  
Deepa Das Achath ◽  
Abhishek Sanjay Ghule ◽  
Preeti Kanchan-Talreja ◽  
Sunanda Bhatnagar
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histological Analysis ◽  
High Recurrence Rate ◽  
Ossifying Fibroma ◽  
Appropriate Treatment ◽  
Juvenile Ossifying Fibroma ◽  
Rare Case Report

ABSTRACT Fibroosseous lesions of the jaws, including juvenile ossifying fibroma (JOF), pose diagnostic and therapeutic difficulties due to their clinical, radiological, and histological variability. There are two histological varieties of it, one as psammomatoid type and second as trebacular type; here, we present a trebacular type, which is a rare variety. After the clinical examination, radiological and histological analysis, it was diagnosed as juvenile trebacular ossifying fibroma. Although JOF is an uncommon clinical entity, its aggressive local behavior and high recurrence rate means that it is important to make an early diagnosis, apply the appropriate treatment, and, especially, follow-up the patient over the long term. How to cite this article Ghule AS, Achath DD, Kanchan- Talreja P, Bhatnagar S. Juvenile Aggressive Trabecular Ossifying Fibroma of Mandible: A Rare Case Report. J Contemp Dent 2016;6(1):45-51.

Hip screening in newborns in the UK: what are the latest guidelines?

2021 ◽  
pp. 1-7
Author(s):  
Ayla C Newton ◽  
Marion Bohatschek ◽  
Andreas Rehm ◽  
Elizabeth Ashby
Keyword(s):  
Physical Examination ◽  
Congenital Abnormalities ◽  
Screening Programme ◽  
Developmental Dysplasia ◽  
Special Focus ◽  
Timely Manner ◽  
Appropriate Treatment ◽  
The Uk

The Newborn and Infant Physical Examination screening is a national screening programme which aims to identify infants with congenital abnormalities to minimise the risk of long-term complications. It involves a top to toe examination with special focus on the heart, eyes, testes and hips. The hip component of the Newborn and Infant Physical Examination screen aims to pick up infants with developmental dysplasia of the hips and refer them for appropriate treatment in a timely manner. Guidelines for the hip section of have recently changed. This article reviews these changes, the timings of the follow up and investigations, and the diagnosis and management of developmental dysplasia of the hips.

scholarly journals Therapeutic options for coarctation of the aorta

2021 ◽  
Vol 16 (2) ◽  
pp. 163-167
Author(s):  
Gabriela GANEA ◽  
◽  
Mihaela Adela IANCU ◽  
Dumitru MATEI ◽  
◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Defects ◽  
Coarctation Of The Aorta ◽  
Systemic Hypertension ◽  
Interventional Treatment ◽  
Appropriate Treatment ◽  
Long Term Follow Up ◽  
Long Term Prognosis

Coarctation of the aorta is a relatively frequent congenital heart disease. Depending on the severity of the coarctation and the possible existence of other congenital heart defects, the symptoms may vary. In the neonatal period, the patients may have signs of heart failure, hypoperfusion or even shock. Coarctation of the aorta can be diagnosed incidentally in adolescence or adulthood, usually presented with mild symptoms. The patient’s anatomy, size, age, and clinical course are taken into consideration when choosing the appropriate treatment. Although associated morbidity and mortality risks regarding surgical or interventional treatment are relatively low, it is neccesary to etabilsh a long term follow-up, given the possible post-surgical complications that may occur: recoarctation, aortic aneurysm, aortic dissection and hypertension. Long term prognosis of these patients mostly depends on the presence of systemic hypertension with its consequences leading to premature cardiovascular events. Another factor is the severity of associated defects: aortic stenosis, mitral valve abnormalities. The purpose of this review is to describe the main treatmet methods, indications for intervention and possible complications of the surgical and interventional treatment.

Localised laryngotracheal amyloidosis: a differential diagnosis not to forget

2021 ◽  
Vol 14 (2) ◽  
pp. e237954
Author(s):  
Catarina Mira ◽  
Pedro Montalvão ◽  
Isabel Fonseca ◽  
Alexandra Borges
Keyword(s):  
High Rate ◽  
Common Site ◽  
Long Latency ◽  
Laryngeal Amyloidosis ◽  
Laryngeal Tumours ◽  
Long Term Follow Up ◽  
High Degree ◽  
Head Neck

We present a case of multifocal laryngotracheal amyloidosis (LTA) in a 43-year-old man with persistent and progressive dysphonia and dyspnoea, and a first inconclusive histology. Although laryngeal amyloidosis accounts for fewer than 1% of all benign laryngeal tumours, it is in fact the most common site of amyloid deposition in the head, neck and respiratory tract. The clinical scenario is non-specific and diagnosis depends on a high degree of suspicion and on histology. Imaging is useful in mapping lesions, which are often more extensive than they appear during laryngoscopy. Despite being a benign entity, the prognosis is variable with a high-rate and long-latency recurrences, requiring long-term follow-up.

scholarly journals Long term assessment of intralipotherapy in Madelung’s disease

2014 ◽  
Vol 47 (03) ◽  
pp. 427-431 ◽  
Author(s):  
Silvia Scevola ◽  
Giovanni Nicoletti ◽  
Antonino Neri ◽  
Angela Faga
Keyword(s):  
Palliative Treatment ◽  
Surgical Excision ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Madelung's Disease ◽  
Madelung’S Disease ◽  
Average Size ◽  
Head Neck

ABSTRACTMadelung’s disease is characterised by multiple symmetric abnormal fat masses in the head, neck and upper limbs. Surgical excision or liposuction is the only realistic available option, although palliative in nature. The serial intralipotherapy with phosphatidylcholine/deoxycholate has been proposed as a non-invasive treatment of Madelung’s disease. The authors used serial intralipotherapy with phosphatidylcholine/deoxycholate in two patients affected by Madelung’s disease. Three injections per lesion per patient were performed with 1 month’s interval. Pre- and 6 months’ post-treatment dimensions were assessed with ultrasound scan and patients were observed along a 5 years’ clinical follow-up. A 42.5% average size reduction was reported in all treated lesions. About 33% recurrence rate was observed in the 5 years’ follow-up. We confirm the efficacy of intralipotherapy in the non-invasive palliative treatment of Madelung’s disease, as a valid option to reduce the volume and limit the growth of the pathological adipose masses.

scholarly journals Endodontic and Prosthetic Management of a Mid-Root and Crown Fracture of a Maxillary Central Incisor

2014 ◽  
Vol 18 (3) ◽  
pp. 144-149
Author(s):  
Vasiliki P. Koidou ◽  
Theodoros Lambrianidis
Keyword(s):  
Tissue Formation ◽  
Central Incisor ◽  
Term Survival ◽  
Maxillary Central Incisor ◽  
Gutta Percha ◽  
Appropriate Treatment ◽  
Root Fractures ◽  
Horizontal Root Fracture

SUMMARYRoot fractures are relatively uncommon among other dental traumas and mostly affect the anterior dentition. This case report presents the endodontic and prosthodontic management of a maxillary central incisor with a combined fracture in the middle third of the root and the crown, as well as the 7-year follow up of the case. The healing potential of a horizontal root fracture in the middle third of the root is highlighted when appropriate treatment is applied. MTA used for obturation of the coronal fragment, induced hard tissue formation apically and promoted healing in the area, while the 2mm MTA left as apical barrier at the second stage of re-treatment and obturation with gutta-percha prevented its extrusion. The multidisciplinary approach in the management of such cases ensures a long term survival.

scholarly journals Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population

2017 ◽  
Vol 49 (11) ◽  
pp. 838-846 ◽  
Author(s):  
Marianne Grytaas ◽  
Siri Strømsøy ◽  
Jarle Rørvik ◽  
Jarle Arnes ◽  
Anette Heie ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Clinical Characteristics ◽  
Diagnostic Procedures ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Confirmatory Testing ◽  
Female Sex ◽  
Norwegian Population

AbstractPrimary aldosteronism (PA) is the most common cause of secondary hypertension (HT). We describe here clinical characteristics, diagnostic procedures, and long-term outcomes in a Norwegian population. All suspected PA patients investigated at a tertiary centre from 1998–2012 were retrospectively evaluated. Inclusion criteria were verified PA after confirmatory testing or otherwise considered highly likely PA. Clinical, biochemical, radiological, and adrenal vein sampling (AVS) findings were analysed. Surgically removed adrenals were re-evaluated histopathologically and tested for somatic mutations. All patients still alive by August 2014 were invited to a follow-up visit. One-hundred and eight patients were included, of whom 85% had a history of hypokalaemia. PA was verified by confirmatory testing in 83 (77%), and AVS performed in 95 (88%) patients. The proportion with AVS-confirmed bilateral PA increased during the study period. Sixty-eight patients (63%) underwent adrenalectomy. KCNJ5 mutations were found in 30% of the surgical specimens and were associated with female sex and a florid PA phenotype. Follow-up visits were undertaken in 73/108 (68%), of whom 52 adrenalectomised. After adrenalectomy, 83% were biochemically cured of PA, but only 21% were cured for HT. Female sex, a verified adenoma, and KCNJ5 mutations were associated with cure of HT. In conclusion, the majority of our patients had unilateral PA and hypokalaemia, indicating that patients with bilateral and milder PA may still be underdiagnosed. Female sex, a histopathological adenoma, and the presence of KCNJ5 mutations predicted cure of HT after adrenalectomy, but the overall cure rate of HT was low.

Consultant Radiographer-led Ultrasound-guided Vacuum Assisted Excision Biopsy

Ultrasound ◽  
2008 ◽  
Vol 16 (4) ◽  
pp. 234-237 ◽  
Author(s):  
Sarah Lawson
Keyword(s):  
Current Evidence ◽  
Excision Biopsy ◽  
Evidence Based ◽  
Breast Lesions ◽  
Ultrasound Guided ◽  
Appropriate Treatment ◽  
Working Practices ◽  
Cost Efficient

The recent introduction of ultrasound-guided vacuum assisted biopsy (VAB) has led to an increase in the non-operative diagnosis of indeterminate breast lesions. Local working practices have evolved in line with current evidence-based research for ultrasound-guided vacuum assisted excision biopsy of a selected group of these indeterminate lesions. Due to service demands and role extension within the professions allied to health, opportunities have arisen to train radiographers with proven expert practice in breast ultrasound in interventional procedures. Departmental policy has been established to support such suitably experienced radiographers to train and undertake this procedure. Aims have been to provide an effective, acceptable, cost-efficient service which can be accessed as an alternative to surgery. This paper demonstrates how with audited training, competence can be established. Discussion of initial experience suggests that once long-term effective follow up is reported, excision VAB could become established as an appropriate treatment for some patients with initial B3 core biopsy histology.

scholarly journals Increased disease activity in early arthritis patients with anti-carbamylated protein antibodies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristina Regueiro ◽  
Laura Nuño ◽  
Ana Triguero-Martinez ◽  
Ana M. Ortiz ◽  
Alejandro Villalba ◽  
...  
Keyword(s):  
Disease Activity ◽  
Early Arthritis ◽  
Prognostic Biomarkers ◽  
Short Term ◽  
Initial Management ◽  
Appropriate Treatment ◽  
Patient Reported ◽  
Activity Measures

AbstractThe initial management of rheumatoid arthritis (RA) has a high impact on disease prognosis. Therefore, we need to select the most appropriate treatment as soon as possible. This goal requires biomarkers of disease severity and prognosis. One such biomarker may be the presence of anti-carbamylated protein antibodies (ACarPA) because it is associated with adverse long term outcomes as radiographic damage and mortality. Here, we have assessed the ACarPA as short-term prognostic biomarkers. The study was conducted in 978 prospective early arthritis (EA) patients that were followed for two years. Our results show the association of ACarPA with increased levels of all the disease activity measures in the first visit after arthritis onset. However, the associations were more significant with the high levels in local measures of inflammation and physician assessment than with the increases in systemic inflammation and patient-reported outcomes. More notably, disease activity was persistently increased in the ACarPA positive patients during the two years of follow-up. These differences were significant even after accounting for the presence of other RA autoantibodies. Therefore, the ACarPA could be considered short-term prognostic biomarkers of increased disease activity in the EA patients.

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