scholarly journals 3D Kinematics and Decision Trees to Predict the Impact of a Physical Exercise Program on Knee Osteoarthritis Patients

2021 ◽  
Vol 11 (2) ◽  
pp. 834
Author(s):  
Marwa Mezghani ◽  
Nicola Hagemeister ◽  
Youssef Ouakrim ◽  
Alix Cagnin ◽  
Alexandre Fuentes ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Decision Trees ◽  
Exercise Program ◽  
Patient Specific ◽  
Pain Level ◽  
Knee Kinematic ◽  
Kinematic Data ◽  
3D Kinematics ◽  
The Impact

Measuring knee biomechanics provides valuable clinical information for defining patient-specific treatment options, including patient-oriented physical exercise programs. It can be done by a knee kinesiography test measuring the three-dimensional rotation angles (3D kinematics) during walking, thus providing objective knowledge about knee function in dynamic and weight-bearing conditions. The purpose of this study was to assess whether 3D kinematics can be efficiently used to predict the impact of a physical exercise program on the condition of knee osteoarthritis (OA) patients. The prediction was based on 3D knee kinematic data, namely flexion/extension, adduction/abduction and external/internal rotation angles collected during a treadmill walking session at baseline. These measurements are quantifiable information suitable to develop automatic and objective methods for personalized computer-aided treatment systems. The dataset included 221 patients who followed a personalized therapeutic physical exercise program for 6 months and were then assigned to one of two classes, Improved condition (I) and not-Improved condition (nI). A 10% improvement in pain was needed at the 6-month follow-up compared to baseline to be in the improved group. The developed model was able to predict I and nI with 84.4% accuracy for men and 75.5% for women using a decision tree classifier trained with 3D knee kinematic data taken at baseline and a 10-fold validation procedure. The models showed that men with an impaired control of their varus thrust and a higher pain level at baseline, and women with a greater amplitude of internal tibia rotation were more likely to report improvements in their pain level after 6 months of exercises. Results support the effectiveness of decision trees and the relevance of 3D kinematic data to objectively predict knee OA patients’ response to a treatment consisting of a physical exercise program.

Photobiomodulation via a cluster device associated with a physical exercise program in the level of pain and muscle strength in middle-aged and older women with knee osteoarthritis: a randomized placebo-controlled trial

2019 ◽  
Vol 35 (1) ◽  
pp. 139-148 ◽  
Author(s):  
Patricia Gabrielli Vassão ◽  
Mayra Cavenague de Souza ◽  
Bruna Arcaim Silva ◽  
Rheguel Grillo Junqueira ◽  
Marcela Regina de Camargo ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Older Women ◽  
Controlled Trial ◽  
Exercise Program ◽  
Middle Aged

scholarly journals The Impact of Moderate Physical Exercise on the Rheological and Biochemical Properties of Blood in Osteoarthritis Patients Who Are Regular Winter Swimmers

2021 ◽  
Vol 69 (1) ◽  
pp. 31-37
Author(s):  
Małgorzata Strzelczyk ◽  
Aneta Teległów ◽  
Jakub Marchewka ◽  
Bartłomiej Ptaszek ◽  
Anna Marchewka
Keyword(s):  
Physical Exercise ◽  
Cold Water ◽  
Water Immersion ◽  
Venous Blood ◽  
Exercise Program ◽  
Blood Parameters ◽  
Cold Water Immersion ◽  
Biochemical Properties ◽  
Rheological Parameters ◽  
The Impact

The aim of this study was to assess the influence of moderate physical exercise on selected blood parameters in regular winter swimmers who suffer from osteoarthritis. The study covered a period of 6 months, from November to April, and was carried out on 17 women and 22 men. The participants were divided into 4 groups: Female CWI – women who only immersed themselves in cold water, Female CWI + PE – women who exercised in addition to water immersion, Male CWI – men who only immersed themselves in cold water, and Male CWI + PE – men, who exercised in addition to water immersion. Venous blood was collected twice, before and after the exercise program. A statistically significant decrease in fibrinogen, plasma viscosity, T ½ , and AMP was observed in the blood of people who did not take part in the physical exercise program while a significant decrease in cortisol levels was observed in the people who participated in the exercise program in addition to cold water immersion. In terms of rheological parameters, a significant increase in the elongation index (EI) of erythrocytes from shear stress 2.19 Pa in all groups was observed. There were no statistically significant changes in AI in all groups. Physical activity has an influence on the blood parameters of elderly winter swimmers suffering from osteoarthritis.

scholarly journals Efficacy of physical exercise program in patients with work-related knee osteoarthritis

2018 ◽  
Vol 69 (1) ◽  
pp. 37-42
Author(s):  
Iulia-Rahela Marcu ◽  
Ion Toma ◽  
Adrian Costin Bighea
Keyword(s):  
Quality Of Life ◽  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Functional Status ◽  
Muscular Strength ◽  
Exercise Program ◽  
Knee Oa ◽  
Work Related ◽  
Sf 36

Abstract Quality of life studies in patients with knee osteoarthritis (OA) attest to the significant impact of the disease on day-to-day activities and social interactions. The aim of this study was to assess the efficacy of a physical exercise program on functional status and quality of life in patients with work-related knee osteoarthritis. The present study included 144 participants with knee osteoarthritis, 72% women, mean age (SD) 47.2 (11.1) years. The patients were randomly assigned in two lots based on the type of kinetic treatment: lot A-with knee OA and medication (72 patients) and lot B- with knee OA, medication and exercise program (72 patients). They followed for 12 days ambulatory exercise programs based on increasing knee flexion, muscular strength and endurance, improving balance, coordination, and respiratory exercises. The patients in the control group continued their daily living activities. The evaluation was made at the beginning of the study (T0), after 2 weeks (T1) and 8 weeks after the 12 days of exercise program (T2) and was based on the following parameters: knee mobility (knee flexion), muscular strength, pain assessment on a Visual Analogue Scale (VAS), functional status (Western Ontario &McMaster Universities Osteoarthritis Index - WOMAC) and quality of life evaluation using SF-36 Questionnaire (36-Item Short Form Survey). Out of 144 participants who completed the initial evaluation, 138 also completed the 2 weeks and the 8 weeks follow-up assessments: 70 patients from the control lot and 68 patients from the exercise lot. The benefits of the kinetic programs were shown by a significant improvement in knee mobility and muscular strength for knee extensors (quadriceps muscle) and knee flexor muscles. Testing the linear correlations between the SF-36 score and the VAS (r=0.71, p<0.05) and WOMAC (r=0.83, p<0.05) indicators demonstrates a highly positive relationship between the quality of life expression, the pain assessment score and the functional status score in patients with knee OA. The physical exercise program improves both functional status and quality of life in patients with work-related knee osteoarthritis by increasing the range of motion and muscular strength and by reducing pain.

scholarly journals Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study

2020 ◽  
Vol 5 (1) ◽  
pp. 10 ◽  
Author(s):  
Goffredo Orlandi ◽  
Francesco Sofi ◽  
Luciano Moscarelli ◽  
Lino Cirami ◽  
Sabrina Mancini ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Physical Exercise ◽  
Mediterranean Diet ◽  
Myocardial Function ◽  
Exercise Program ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Home Based ◽  
The Mediterranean ◽  
The Impact

Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary lifestyle prior to transplantation. This study aimed to evaluate the impact of unsupervised intervention in a tailored home-based aerobic resistance exercise program, based on the anthropometric and cardiovascular parameters in a group of renal transplant recipients (RTRs) followed for 12 months. Methods: a group of 21 RTRs (mean age: 46.8 ± 12 years) were enrolled in a combined aerobic and step count unsupervised prescription program. Body composition (BMI, waist circumferences, skin-folds); water distribution (TBW: Total body water; ECW: Extra cellular water; and ICW: Intracellular water) and myocardial function were measured every 6 months for 1 year. The MEDI-LITE score was used to estimate adherence to the Mediterranean diet. Results: Significant reductions in waist circumference (Waist Cir: 89.12 ± 12.8 cm T0; 89.1 ± 12.5 cm T6 (95% CI: 6.3, 5.7); 88.6 ± 11.4 cm T12; (95% CI: 6.7, 4.7) p < 0.01), weight:71.8 ± 14.8 kg T0; 70.6 ± 14.7 kg T6(95% CI:−8, 6); 70.6 ± 14.7 kg T12(95% CI: 6.6, 7) p < 0.05), as well as an improvement of myocardial function, as shown by the significant increase of contractility and change in the GLS % value (−18.3 ± 3.8% at T0 (95% CI:−16.57, 20.0.2)−20.4 ± 3.0% at T6(95% CI:−4, 0.2);−22.9 ± 3.1%T12(95% CI:−3, 4, −1, 6) p < 0.02), were observed. Adherence to the Mediterranean diet was in the normal range. Conclusions: Despite unsupervised intervention, combined moderate physical exercise appears to have a positive effect on the main parameters related to cardiovascular risk factors. The long-term efficacy of this program requires further investigation, particularly for evaluating constant adherence to the home-based physical exercise program.

scholarly journals Effectiveness of Combined Treatment Using Physical Exercise and Ultrasound-Guided Radiofrequency Ablation of Genicular Nerves in Patients with Knee Osteoarthritis

2021 ◽  
Vol 11 (10) ◽  
pp. 4338
Author(s):  
Alessandro de Sire ◽  
Lorenzo Lippi ◽  
Claudio Curci ◽  
Dario Calafiore ◽  
Carlo Cisari ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Rating Scale ◽  
Combined Treatment ◽  
Exercise Program ◽  
Exercise Adherence ◽  
Reduction Of Pain ◽  
Chronic Pain Conditions ◽  
Combined Intervention

Radiofrequency (RF) is a mini-invasive neuromodulation intervention that is commonly used in chronic pain conditions including general musculoskeletal pain related to several diseases, including knee osteoarthritis (KOA). However, to date, few studies investigated synergistic therapeutic approaches combining RF with rehabilitative physical exercise protocols in KOA patients. This prospective cohort study aimed at assessing the short-term effects on pain in KOA patients of a multimodal intervention consisting of ultrasound (US)-guided RF geniculate ablation and concomitant rehabilitative physical exercise. We included grade III KOA patients with knee pain (Numerical Pain Rating Scale, NPRS >4) not responsive to conventional treatments. They underwent a combined intervention including US-guided RF geniculate ablation and a 2-week physical exercise program. At the baseline (T0) and 1 month after (T1) we assessed: NPRS, Knee Injury and Osteoarthritis Outcome Scale (KOOS), quality of life, exercise adherence, and safety. All the 47 KOA patients enrolled (68.8 ± 13.7 years old) showed a reduction of pain (NPRS: 7.48 ± 1.74; 3.63 ± 1.68; p < 0.001). In addition, there was a significant improvement (p < 0.05) also in the other functioning and HRQoL outcomes. Adherence to the exercise program was over 80% in more than half (28) of the patients. No major adverse events were reported. These findings suggested that US-guided RF ablation of genicular nerves combined with rehabilitative exercise therapy might be considered a safe and effective approach in the complex management of KOA patients.

scholarly journals Cardiovascular benefits of a home-based exercise program in patients with sickle cell disease

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0250128
Author(s):  
Jonas Alves de Araujo Junior ◽  
Daniele Andreza Antonelli Rossi ◽  
Taina Fabri Carneiro Valadão ◽  
Juliana Cristina Milan-Mattos ◽  
Aparecida Maria Catai ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Physical Exercise ◽  
Sickle Cell ◽  
Exercise Program ◽  
Cardiovascular Function ◽  
Exercise Group ◽  
Cell Disease ◽  
Home Based ◽  
Cardiovascular Tests ◽  
The Impact

Background Physical inactivity is an important risk factor for cardiovascular disease. The benefits of exercise in patients with chronic diseases, including cardiovascular diseases, are well established. For patients with sickle cell disease, medical recommendation was to avoid physical exercise for fear of triggering painful crises or increasing the impairment of the cardiopulmonary function. Only recently, studies have shown safety in exercise programs for this population. Despite that, there is no report that assess the effects of physical exercise on cardiac parameters in patients with sickle cell disease. Objective This study aimed to evaluate the impact of regular physical exercise (a home-based program) on cardiovascular function in patients with sickle cell disease. Design A quasi-randomized prospective controlled trial. Setting During the years 2015 and 2016, we started recruiting among adult patients treated at a Brazilian Center for Patients with Sickle Cell Disease to participate in a study involving a home exercise program. The experimental (exercise) and control groups were submitted to clinical evaluation and cardiovascular tests before and after the intervention. Analysis of variance was applied to compare groups, considering time and group factors. Participants Twenty-seven adult outpatients with a sickle cell disease diagnosis. Interventions Exercise group (N = 14): a regular home-based aerobic exercise program, three to five times per week not exceeding give times per week, for eight weeks; no prescription for the control group (N = 13). Main outcome measures Echocardiographic and treadmill test parameters. Results The exercise group showed significant improvement in cardiovascular tests, demonstrated by increased distance traveled on a treadmill (p<0.01), increased ejection fraction (p < 0.01) and improvement of diastolic function assessed by mitral tissue Doppler E’ wave on echocardiography (p = 0.04). None of the patients presented a sickle cell crisis or worsening of symptoms during the exercise program. Conclusion The selected home-based exercise program is safe, feasible, and promotes a favorable impact on functional capacity and cardiovascular function in sickle cell disease patients.

scholarly journals Effects of photobiomodulation and a physical exercise program on the expression of inflammatory and cartilage degradation biomarkers and functional capacity in women with knee osteoarthritis: a randomized blinded study

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Patricia Gabrielli Vassão ◽  
Ana Carolina Flygare de Souza ◽  
Raquel Munhoz da Silveira Campos ◽  
Livia Assis Garcia ◽  
Helga Tatiana Tucci ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Functional Capacity ◽  
Exercise Program ◽  
Cartilage Degradation ◽  
Post Treatment ◽  
Joint Disease ◽  
Control Group ◽  
Knee Oa ◽  
And Cartilage

Abstract Background The knee osteoarthritis (OA) is a joint disease characterized by degradation of articular cartilage that leads to chronic inflammation. Exercise programs and photobiomodulation (PBM) are capable of modulating the inflammatory process of minimizing functional disability related to knee OA. However, their association on the concentration of biomarkers related to OA development has not been studied yet. The aim of the present study is to investigate the effects of PBM (via cluster) with a physical exercise program in functional capacity, serum inflammatory and cartilage degradation biomarkers in patients with knee OA. Methods Forty-two patients were randomly allocated in 3 groups: ESP: exercise + sham PBM; EAP: exercise + PBM and CG: control group. Six patients were excluded before finished the experimental period. The analyzed outcomes in baseline and 8-week were: the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) and the evaluation of serum biomarkers concentration (IL-1β, IL-6, IL-8, IL-10 e TNF-α, and CTX-II). Results An increase in the functional capacity was observed in the WOMAC total score for both treated groups (p < 0.001) and ESP presents a lower value compared to CG (p < 0.05) the 8-week post-treatment. In addition, there was a significant increase in IL-10 concentration of EAP (p < 0.05) and higher value compared to CG (p < 0.001) the 8-week post-treatment. Moreover, an increase in IL-1β concentration was observed for CG (p < 0.05). No other difference was observed comparing the other groups. Conclusion Our data suggest that the physical exercise therapy could be a strategy for increasing functional capacity and in association with PBM for increasing IL-10 levels in OA knee individuals. Trial registration: ReBEC (RBR-7t6nzr).

scholarly journals An analysis of 3D knee kinematic data complexity in knee osteoarthritis and asymptomatic controls

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0202348 ◽  
Author(s):  
Neila Mezghani ◽  
Imene Mechmeche ◽  
Amar Mitiche ◽  
Youssef Ouakrim ◽  
Jacques A. de Guise
Keyword(s):  
Knee Osteoarthritis ◽  
Data Complexity ◽  
Knee Kinematic ◽  
Kinematic Data
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