scholarly journals Non-Enzymatic Amperometric Glucose Screen-Printed Sensors Based on Copper and Copper Oxide Particles

2021 ◽  
Vol 11 (22) ◽  
pp. 10830
Author(s):  
Carlota Guati ◽  
Lucía Gomez-Coma ◽  
Marcos Fallanza ◽  
Inmaculada Ortiz

Non-enzymatic amperometric glucose sensors have gained much attention in the past decade because of the better chemical and thermal stability and biocompatibility compared to conventional sensors based on the use of biomolecules. This study focuses on a novel copper and copper oxide-based glucose sensor synthesized by an electrodeposition technique through a rigorous protocol which reports an excellent analytical performance due to its structure and its increased active area. In addition, the linear response range, detection limit and sensitivity were 0.5–5.0 mmol L−1, 0.002 mmol L−1, 904 μA mmol−1 L−1 cm−2, respectively. Results show a reliable electrode as it is chemically stable, exhibits rapid and excellent sensitivity, and it is not significantly affected by coexisting species present in the blood samples; furthermore, it reports a maximum relative standard deviation error (RSD) of 6%, and showed long operating life as the electrode was used for thousand measurements of 4.0 mmol L−1 glucose solution during three days.

RSC Advances ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 6613-6619 ◽  
Author(s):  
Mengzhu Liu ◽  
Yongpeng Wang ◽  
Haibo Zhang ◽  
Zhenhua Jiang

3-D network films of rope-like CuO-MNFs with high surface-to-volume ratio were prepared. The product is a promising electrode material for fabrication of amperometric enzymeless glucose sensors.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Xiaoxu Ji ◽  
Aihua Wang ◽  
Qinghuai Zhao

Copper oxide (CuO) films directly grown on Ti substrate have been successfully prepared via a hydrothermal method and used to construct an amperometric nonenzymatic glucose sensor. XRD and SEM were used to characterize the samples. The electrochemical performances of the electrode for detection of glucose were investigated by cyclic voltammetry and chronoamperometry. The CuO films based glucose sensors exhibit enhanced electrocatalytic properties which show very high sensitivity (726.9 μA mM−1 cm−2), low detection limit (2 μM), and fast response (2 s). In addition, reproducibility and long-term stability have been observed. Low cost, convenience, and biocompatibility make the CuO films directly grown on Ti substrate electrodes a promising platform for amperometric nonenzymatic glucose sensor.


2015 ◽  
Vol 29 (06n07) ◽  
pp. 1540045 ◽  
Author(s):  
Pankaj Koinkar ◽  
Sumedh Gaikwad ◽  
Gajanan Bodkhe ◽  
Megha Deshmukh ◽  
Harshada Patil ◽  
...  

In the present investigation, a glucose sensor based on conducting polyaniline nanowire electrode junction (CPNEJ) has been reported. The CPNEJ platform was modified by glucose oxidase by cross-linking in the presence of glutaraldehyde. The signal transduction mechanism of the sensor is based on the change in micro electrode junction conductance as a result of glucose oxidation induced change in the polymer redox state. Small size of CPNEJ sensor causes to regenerate enzyme naturally without need of redox mediators, as a result it consumes minimum amount of oxygen and also gives very fast response. This sensor exhibited good linear response range from 1 mM to 20 mM of glucose concentration with excellent sensitivity of 12 μA/mM.


Author(s):  
Lorna K. Mayo ◽  
Kenneth C. Moore ◽  
Mark A. Arnold

An implantable artificial endocrine pancreas consisting of a glucose sensor and a closed-loop insulin delivery system could potentially replace the need for glucose self-monitoring and regulation among insulin dependent diabetics. Achieving such a break through largely depends on the development of an appropriate, biocompatible membrane for the sensor. Biocompatibility is crucial since changes in the glucose sensors membrane resulting from attack by orinter action with living tissues can interfere with sensor reliability and accuracy. If such interactions can be understood, however, compensations can be made for their effects. Current polymer technology offers several possible membranes that meet the unique chemical dynamics required of a glucose sensor. Two of the most promising polymer membranes are polytetrafluoroethylene (PTFE) and silicone (Si). Low-voltage scanning electron microscopy, which is an excellent technique for characterizing a variety of polymeric and non-conducting materials, 27 was applied to the examination of experimental sensor membranes.


2020 ◽  
Vol 12 (49) ◽  
pp. 55362-55371
Author(s):  
Tingting Zhao ◽  
Li Yuan ◽  
Tongkuai Li ◽  
Longlong Chen ◽  
Xifeng Li ◽  
...  

2021 ◽  
Vol 875 ◽  
pp. 160063
Author(s):  
Veeramani Vediyappan ◽  
Mani Sivakumar ◽  
Shen-Ming Chen ◽  
Qiwen Lai ◽  
Rajesh Madhu

2021 ◽  
Author(s):  
R. L. Kalyani ◽  
Sarath Chandra Veerla ◽  
Venkata Ramana Murthy Kolapalli ◽  
Vijay Kumar P.P.N. ◽  
V. Swamy P. ◽  
...  

In the present study, Annona squamosa leaf extract was used as a reducing and capping agent for the facile green synthesis of nano-copper oxide particles. The optical, structural and morphological...


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Kristina Gudun ◽  
Zarina Elemessova ◽  
Laura Khamkhash ◽  
Ekaterina Ralchenko ◽  
Rostislav Bukasov

We introduce low-cost, tunable, hybrid SERS substrate of commercial gold nanoparticles on untreated aluminum foil (AuNPs@AlF). Two or three AuNP centrifugation/resuspension cycles are proven to be critical in the assay preparation. The limits of detection (LODs) for 4-nitrobenzenethiol (NBT) and crystal violet (CV) on this substrate are about 0.12 nM and 0.19 nM, respectively, while maximum analytical SERS enhancement factors (AEFs) are about 107. In comparative assays LODs for CV measured on AuNPs@Au film and AuNPs@glass are about 0.35 nM and 2 nM, respectively. The LOD for melamine detected on AuNPs@ Al foil is 27 ppb with 3 orders of magnitude for linear response range. Overall, AuNPs@AlF demonstrated competitive performance in comparison with AuNPs@ Au film substrate in SERS detection of CV, NBT, and melamine. To check the versatility of the AuNPs@AlF substrate we also detected KNO3 with LODs of 0.7 mM and SERS EF around 2 × 103, which is on the same order with SERS EF reported for this compound in the literature.


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