scholarly journals Protein-Based 3D Biofabrication of Biomaterials

2021 ◽  
Vol 8 (4) ◽  
pp. 48
Author(s):  
Mahta Mirzaei ◽  
Oseweuba Valentine Okoro ◽  
Lei Nie ◽  
Denise Freitas Siqueira Petri ◽  
Amin Shavandi
Keyword(s):  
3D Printing ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Native Structure ◽  
Cross Link ◽  
Primary Mechanism ◽  
Protein Gelation ◽  
Physical Gelation ◽  
Printing Processes ◽  
Gel Network

Protein/peptide-based hydrogel biomaterial inks with the ability to incorporate various cells and mimic the extracellular matrix’s function are promising candidates for 3D printing and biomaterials engineering. This is because proteins contain multiple functional groups as reactive sites for enzymatic, chemical modification or physical gelation or cross-linking, which is essential for the filament formation and printing processes in general. The primary mechanism in the protein gelation process is the unfolding of its native structure and its aggregation into a gel network. This network is then stabilized through both noncovalent and covalent cross-link. Diverse proteins and polypeptides can be obtained from humans, animals, or plants or can be synthetically engineered. In this review, we describe the major proteins that have been used for 3D printing, highlight their physicochemical properties in relation to 3D printing and their various tissue engineering application are discussed.

scholarly journals 3D-Printed Biopolymers for Tissue Engineering Application

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Xiaoming Li ◽  
Rongrong Cui ◽  
Lianwen Sun ◽  
Katerina E. Aifantis ◽  
Yubo Fan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Three Dimensional ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Potential Applications ◽  
3D Printed ◽  
Dimensional Object

3D printing technology has recently gained substantial interest for potential applications in tissue engineering due to the ability of making a three-dimensional object of virtually any shape from a digital model. 3D-printed biopolymers, which combine the 3D printing technology and biopolymers, have shown great potential in tissue engineering applications and are receiving significant attention, which has resulted in the development of numerous research programs regarding the material systems which are available for 3D printing. This review focuses on recent advances in the development of biopolymer materials, including natural biopolymer-based materials and synthetic biopolymer-based materials prepared using 3D printing technology, and some future challenges and applications of this technology are discussed.

scholarly journals Cartilage Repair and Subchondral Bone Migration Using 3D Printing Osteochondral Composites: A One-Year-Period Study in Rabbit Trochlea

2014 ◽  
Vol 2014 ◽  
pp. 1-16 ◽  
Author(s):  
Weijie Zhang ◽  
Qin Lian ◽  
Dichen Li ◽  
Kunzheng Wang ◽  
Dingjun Hao ◽  
...  
Keyword(s):  
3D Printing ◽  
Cartilage Repair ◽  
Subchondral Bone ◽  
Critical Size ◽  
Cartilage Damage ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Defect Center ◽  
Osteochondral Repair ◽  
And Migration

Increasing evidences show that subchondral bone may play a significant role in the repair or progression of cartilage damagein situ. However, the exact change of subchondral bone during osteochondral repair is still poorly understood. In this paper, biphasic osteochondral composite scaffolds were fabricated by 3D printing technology using PEG hydrogel andβ-TCP ceramic and then implanted in rabbit trochlea within a critical size defect model. Animals were euthanized at 1, 2, 4, 8, 16, 24, and 52 weeks after implantation. Histological results showed that hyaline-like cartilage formed along with white smooth surface and invisible margin at 24 weeks postoperatively, typical tidemark formation at 52 weeks. The repaired subchondral bone formed from 16 to 52 weeks in a “flow like” manner from surrounding bone to the defect center gradually. Statistical analysis illustrated that both subchondral bone volume and migration area percentage were highly correlated with the gross appearance Wayne score of repaired cartilage. Therefore, subchondral bone migration is related to cartilage repair for critical size osteochondral defects. Furthermore, the subchondral bone remodeling proceeds in a “flow like” manner and repaired cartilage with tidemark implies that the biphasic PEG/β-TCP composites fabricated by 3D printing provides a feasible strategy for osteochondral tissue engineering application.

Preparation and Characterization of PLA Film/3D Printing Composite Scaffold for Tissue Engineering Application

2020 ◽  
Vol 21 (4) ◽  
pp. 709-716
Author(s):  
Chenjie Meng ◽  
Jiaming Zhao ◽  
Yuxiang Yin ◽  
Jun Luo ◽  
Lianying Zhao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Composite Scaffold ◽  
Engineering Application ◽  
Tissue Engineering Application

A review on biocompatibility nature of hydrogels with 3D printing techniques, tissue engineering application and its future prospective

2018 ◽  
Vol 1 (4) ◽  
pp. 265-279 ◽  
Author(s):  
Jabran Saroia ◽  
Wang Yanen ◽  
Qinghua Wei ◽  
Kun Zhang ◽  
Tingli Lu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Printing Techniques

scholarly journals Synthesis of a photocurable acrylated poly(ethylene glycol)-co-poly(xylitol sebacate) copolymers hydrogel 3D printing ink for tissue engineering

RSC Advances ◽  
2019 ◽  
Vol 9 (32) ◽  
pp. 18394-18405 ◽  
Author(s):  
Yicai Wang ◽  
Yuan Li ◽  
Xiaoling Yu ◽  
Qizhi Long ◽  
Tian Zhang
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Ethylene Glycol ◽  
Engineering Application ◽  
Cell Encapsulation ◽  
Tissue Engineering Application ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Printing Ink

A novel acrylated poly(ethylene glycol)-co-poly(xylitol sebacate) (PEXS-A) hydrogel for 3D printing ink and cell encapsulation for tissue engineering application.

Influence of Constructive and Technological Parameters at Generated Spiral Parts with DLP 3D Printing Process

2019 ◽  
Vol 56 (4) ◽  
pp. 801-811
Author(s):  
Mircea Dorin Vasilescu
Keyword(s):  
3D Printing ◽  
Great Influence ◽  
Polymerization Process ◽  
Generation Process ◽  
Technological Parameters ◽  
Printing Process ◽  
The Third ◽  
Solid Models ◽  
Specific Factors ◽  
Printing Processes

This work are made for determine the possibility of generating the specific parts of a threaded assembly. If aspects of CAD generating specific elements was analysed over time in several works, the technological aspects of making components by printing processes 3D through optical polymerization process is less studied. Generating the threaded appeared as a necessity for the reconditioning technology or made components of the processing machines. To determine the technological aspects of 3D printing are arranged to achieve specific factors of the technological process, but also from the specific elements of a trapezoidal thread or spiral for translate granular material in supply process are determined experimentally. In the first part analyses the constructive generation process of a spiral element. In the second part are identified the specific aspects that can generation influence on the process of realization by 3D DLP printing of the two studied elements. The third part is affected to printing and determining the dimensions of the analysed components. We will determine the specific value that can influence the process of making them in rapport with printing process. The last part is affected by the conclusions. It can be noticed that both the orientation and the precision of generating solid models have a great influence on the made parts.

Coating of Laponite on PLA Nanofibrous for Bone Tissue Engineering Application

2021 ◽  
Vol 29 (3) ◽  
pp. 191-198
Author(s):  
Zahra Orafa ◽  
Shiva Irani ◽  
Ali Zamanian ◽  
Hadi Bakhshi ◽  
Habib Nikukar ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Engineering Application ◽  
Tissue Engineering Application ◽  
Bone Tissue Engineering Application

scholarly journals Development of a Decision Support System for 3D Printing Processes based on Cyber Physical Production Systems

Procedia CIRP ◽  
2021 ◽  
Vol 98 ◽  
pp. 348-353
Author(s):  
Rishi Kumar ◽  
Christopher Rogall ◽  
Sebastian Thiede ◽  
Christoph Herrmann ◽  
Kuldip Singh Sangwan
Keyword(s):  
Decision Support ◽  
3D Printing ◽  
Decision Support System ◽  
Support System ◽  
Production Systems ◽  
Cyber Physical Production Systems ◽  
Printing Processes
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