Peri-Implantitis Regenerative Therapy: A Review

The surgical techniques available to clinicians to treat peri-implant diseases can be divided into resective and regenerative. Peri-implant diseases are inflammatory conditions affecting the soft and hard tissues around dental implants. Despite the large number of investigations aimed at identifying the best approach to treat these conditions, there is still no universally recognized protocol to solve these complications successfully and predictably. This review will focus on the regenerative treatment of peri-implant osseous defects in order to provide some evidence that can aid clinicians in the approach to peri-implant disease treatment.

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Titanium Wear of Dental Implants from Placement, under Loading and Maintenance Protocols

International Journal of Molecular Sciences ◽

10.3390/ijms22031067 ◽

2021 ◽

Vol 22 (3) ◽

pp. 1067

Author(s):

Georgios Romanos ◽

Gerard Fischer ◽

Rafael Delgado-Ruiz

Keyword(s):

Adverse Effects ◽

Inflammatory Response ◽

Dental Implants ◽

Soft Tissues ◽

Loading Conditions ◽

Material Change ◽

Implant Placement ◽

Implant Abutment ◽

Hard Tissues ◽

Titanium Nanoparticles

The objective of this review was to analyze the process of wear of implants leading to the shedding of titanium particles into the peri-implant hard and soft tissues. Titanium is considered highly biocompatible with low corrosion and toxicity, but recent studies indicate that this understanding may be misleading as the properties of the material change drastically when titanium nanoparticles (NPs) are shed from implant surfaces. These NPs are immunogenic and are associated with a macrophage-mediated inflammatory response by the host. The literature discussed in this review indicates that titanium NPs may be shed from implant surfaces at the time of implant placement, under loading conditions, and during implant maintenance procedures. We also discuss the significance of the micro-gap at the implant-abutment interface and the effect of size of the titanium particles on their toxicology. These findings are significant as the titanium particles can have adverse effects on local soft and hard tissues surrounding implants, implant health and prognosis, and even the health of systemic tissues and organs.

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Comparative radiographic and resonance frequency analyses of the peri-implant tissue after dental implants placement using flap and flapless techniques: An experimental study on domestic pigs

Vojnosanitetski pregled ◽

10.2298/vsp1306586v ◽

2013 ◽

Vol 70 (6) ◽

pp. 586-594 ◽

Cited By ~ 6

Author(s):

Zoran Vlahovic ◽

Branko Mihailovic ◽

Zoran Lazic ◽

Mileta Golubovic

Keyword(s):

Bone Resorption ◽

Resonance Frequency ◽

Dental Implants ◽

Dental Implant ◽

Surgical Techniques ◽

Primary Stability ◽

Implant Stability ◽

Domestic Pigs ◽

Flap Technique ◽

Implant Placement

Background/Aim. Flapless implant surgery has become very important issue during recent years, mostly thanks to computerization of dentistry and software planning of dental implants placements. The aim of this study was to compare flap and flapless surgical techniques for implant placement through radiographic and radiofrequency analyses. Methods. The experiment was made in five domestic pigs. Nine weeks following domestic pigs teeth extraction, implants were placed, on the right side using surgical technique flap, and flapless on the left side. Digital dental Xrays were applied to determine primary dental implant stability quality (ISQ). At certain intervals, not later than three months, the experimental animals were sacrificed, and just before it, control X-rays were applied to measure dental implants stability. Results. Radiographic analysis showed that peri-implant bone resorption in the first 4 weeks following placement implants with flap and flapless surgical techniques was negligible. After the 3 months, mean value of peri-implant bone resorption of the implants placed using flap technique was 1.86 mm, and of those placed using flapless technique was 1.13 mm. In relation to the primary dental implant stability in the first and second week there was an expected decrease in ISQ values, but it was less expressed in the dental implants placed using the flapless technique. In the third week the ISQ values were increased in the dental implants placed by using both techniques, but the increase in flapless implant placement was higher (7.4 ISQ) than in flap implant placement (1.5 ISQ). The upward trend continued in a 4- week period, and after 3 months the dental implant stability values in the implants placed using flap technique were higher than the primary stability for 7.1 ISQ, and in the implants placed using flapless technique were higher comparing to the primary stability for 10.1 ISQ units. Conclusion. Based on the results of radiographic and resonance frequency analyses it can be concluded that the flapless technique in surgical implants placemat, leads to better results.

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Vertical bone augmentation of posterior mandibular region: a description of two surgical techniques

RGO - Revista Gaúcha de Odontologia ◽

10.1590/1981-8637201600030000143128 ◽

2016 ◽

Vol 64 (3) ◽

pp. 333-336

Author(s):

Adalmir Gonzaga dos Santos QUEIROZ ◽

Yuri Slusarenko da SILVA ◽

Pedro Jorge Cavalcante COSTA ◽

Flávio Wellington da Silva FERRAZ ◽

Maria da Graça NACLÉRIO-HOMEM

Keyword(s):

Bone Loss ◽

Dental Implants ◽

Case Reports ◽

Surgical Techniques ◽

The Other ◽

Bone Maturation ◽

Oral Rehabilitation ◽

Autologous Graft ◽

Mandibular Region ◽

Graft Interposition

ABSTRACT Correction of severe vertical bone deficiency in the posterior region of mandibular alveolar ridge requires surgical management if implants are scheduled and cannot have primary stability. The aim of the present study is to report two cases; one treated with alveolar osteogenesis distraction and the other with segmental osteotomy with autologous graft interposition, by describing the surgical steps as well as show the results and experiences acquired with these techniques. We opted for these methods to reconstruct the posterior mandibular region after remarkable vertical bone loss based mainly by the height and thickness of the remaining bone. Alveolar osteogenic distraction is highly advisable when vertical deficiency is severe, and if these cases are treated with the segmental osteotomy and autologous graft interposition, complications as graft failure, necrosis and resorption are more prone to occur due to insufficient vascularization. After bone maturation and bone neoformation secondary to alveolar osteogenic osteogenic distraction and segmental osteotomy with autologous graft interposition, respectively, the two presented case reports were able to securely receive dental implants. In cases of vertical bone loss of the posterior mandibular region, both surgeries currently represent the best choice for bone gain prior dental implants placement for oral rehabilitation, without technical challenges, although biological evidence to assure the superiority of one technique over the other must be further investigated.

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Treatment of Severely Atrophic Edentulous Mandible Fractures: Load-Bearing or Load-Sharing?

Craniomaxillofacial Trauma & Reconstruction Open ◽

10.1055/s-0038-1667295 ◽

2018 ◽

Vol 2 (1) ◽

pp. s-0038-1667295

Author(s):

Celine A. Van der Kolk - Bender ◽

Maarten J. Koudstaal ◽

Eppo B. Wolvius

Keyword(s):

Dental Implants ◽

Surgical Techniques ◽

Fracture Repair ◽

Multiple Fracture ◽

Reconstruction Plate ◽

Oral Rehabilitation ◽

Load Bearing ◽

Edentulous Mandible ◽

Gunning Splint ◽

Mandible Fractures

Several nonsurgical and surgical techniques have been employed to treat fractures of the severely atrophic mandible. The aim of this study was to analyze the repair outcome of these fractures. From 2010 to 2016, patients with fractures of the severely atrophic mandible were included. All files were retrospectively studied. Twelve patients (mean age: 76 years; female, n = 8) with a single ( n = 6) or multiple fracture(s) of the atrophic edentulous mandible (mean height was 10.1 mm) were identified. Fracture occurred following trauma ( n = 9), explantation of dental implants ( n = 2), and placing an overdenture bar ( n = 1). In seven cases, consolidation was successful following open reduction and internal fixation (ORIF) using a load-bearing reconstruction plate. In five cases, the initial treatment was different: conservative treatment, using gunning splint, and performing ORIF using miniplates. In all five cases, additional ORIF using a load-bearing reconstruction plate was needed. In four cases, short dental implants were placed several months following fracture repair. In case of a severely atrophic mandibular fracture, the authors advise ORIF with a load-bearing reconstruction plate. In selected cases, secondary oral rehabilitation with short dental implants and implant-supported prosthesis is feasible.

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Diagnosis and treatment of sacroiliac joint region pain in horses

UK-Vet Equine ◽

10.12968/ukve.2021.5.4.150 ◽

2021 ◽

Vol 5 (4) ◽

pp. 150-157

Author(s):

John David Stack ◽

Jessica Harley

Keyword(s):

Diagnostic Imaging ◽

Diagnostic Test ◽

Sacroiliac Joint ◽

Joint Pain ◽

Surgical Techniques ◽

The Body ◽

Anecdotal Evidence ◽

Joint Region ◽

Disease Treatment ◽

Presumptive Diagnosis

The sacroiliac joint and pain deriving from this complex region remains poorly understood in horses, although our understanding grows as the body of literature grows. A deeper understanding can be derived from the richer body of literature in human sacroiliac joint pain as the disease processes and biomechanics appear similar in both species. A highly specific and sensitive diagnostic test for this condition does not exist, so equine clinicians have to make presumptive diagnosis based on presenting signs, findings of clinical examination, diagnostic imaging and the response to blocking of the sacroiliac joint region. Many horses with sacroiliac joint region pain have concurrent orthopaedic injury or disease. Treatment is largely based on fundamentals, anecdotal evidence and translation of non-surgical techniques used in humans. Treatment for other orthopaedic conditions can conflict with rehabilitation for sacroiliac joint region pain, necessitating compromise.

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The use of lyodura for bone augmentation of osseous defects around dental implants

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/s0901-5027(99)80733-4 ◽

1999 ◽

Vol 28 ◽

pp. 22

Author(s):

M. Peleg ◽

G. Chaushu ◽

S. Taicher

Keyword(s):

Dental Implants ◽

Bone Augmentation ◽

Osseous Defects

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Use of Lyodura for Bone Augmentation of Osseous Defects Around Dental Implants

Journal of Periodontology ◽

10.1902/jop.1999.70.8.853 ◽

1999 ◽

Vol 70 (8) ◽

pp. 853-860 ◽

Cited By ~ 5

Author(s):

Michael Peleg ◽

Gavriel Chaushu ◽

Daniella Blinder ◽

Shlomo Taicher

Keyword(s):

Dental Implants ◽

Bone Augmentation ◽

Osseous Defects

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Nonprocessed Adipose Tissue Graft in the Treatment of Peri-Implant Osseous Defects in the Rabbit's Tibiae: A Pilot Study

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-11-00149 ◽

2014 ◽

Vol 40 (1) ◽

pp. 60-66

Author(s):

Diogo Godoy Zanicotti ◽

Fernanda Brugin Matsubara ◽

João César Zielak ◽

Allan Fernando Giovanini ◽

Cícero de Andrade Urban ◽

...

Keyword(s):

Adipose Tissue ◽

Pilot Study ◽

Bone Formation ◽

Dental Implants ◽

New Technique ◽

Tissue Graft ◽

Bone To Implant Contact ◽

A New Technique ◽

Osseous Defect ◽

Osseous Defects

We hypothesized that a new technique using nonprocessed adipose tissue could regenerate bone around dental implants. Eighteen rabbits received 1 implant per tibia surrounded by a surgically created osseous defect. The defects were assigned for treatment into 3 groups: C, AT, and AB. The percentages of bone-to-implant contact were 17.64% ± 16.22% (AB), 3.54% ± 7.08% (AT), and 12.71% ± 10.11% (C) (ρ = 0.25). The use of adipose tissue around surgically created peri-implant osseous defects interferes with bone formation.

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