scholarly journals Histamine Intolerance: The Current State of the Art

Biomolecules ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1181 ◽  
Author(s):  
Oriol Comas-Basté ◽  
Sònia Sánchez-Pérez ◽  
Maria Teresa Veciana-Nogués ◽  
Mariluz Latorre-Moratalla ◽  
María del Carmen Vidal-Carou

Histamine intolerance, also referred to as enteral histaminosis or sensitivity to dietary histamine, is a disorder associated with an impaired ability to metabolize ingested histamine that was described at the beginning of the 21st century. Although interest in histamine intolerance has considerably grown in recent years, more scientific evidence is still required to help define, diagnose and clinically manage this condition. This article will provide an updated review on histamine intolerance, mainly focusing on its etiology and the existing diagnostic and treatment strategies. In this work, a glance on histamine intoxication will also be provided, as well as the analysis of some uncertainties historically associated to histamine intoxication outbreaks that may be better explained by the existence of interindividual susceptibility to ingested histamine.

Author(s):  
Marvin C. Gridley ◽  
Steven H. Walker

The focus of propulsion integration technology in the 21st century will be economy. USAF inlet and nozzle technology goals translate into 50% weight reduction and 25% acquisition cost reduction metrics for new aircraft system. Innovative technology to enable these reductions over current state-of-the-art systems in weight and cost is required. For inlet systems, compact diffusers that reduce system volume by 50% will demand fewer parts and improved aerodynamic performance. Exhaust systems will be fixed with fewer parts, requiring a technology like fluidics, for example, to provide area control and thrust vectoring capabilities. Cooperative programs for both inlet and nozzle systems are in place to insure that technologies required to meet weight and cost reduction goals are matured by the year 2000.


Author(s):  
Md. Mahmudul Amin

Diabetes is a major public health problem which has been increasing day by day throughout the world with an alarming rate. In recent years, several plant extracts have been examined for their anti-diabetic properties to identify alternative treatment strategies that pose less risk for diabetes. It has been shown that different parts of these plants are collected from diverse regions and administered in different pharmaceutical preparations. The aim of the present review is to provide an overview of the phytochemicals present in S. cumini plants and their potent anti-diabetic activity, toxicological and biological effects of these plant extracts, their current state, limitation and future prospects in developing countries that are not included in the European Pharmacopoeia. In addition, a prospective research result of synergistic use of this plant with other plant (Ficus racemosa) done presently in our laboratory has been included. Based on the available evidence, we highlight the ways in which their therapeutic potential can be properly harnessed and provide scientific evidence for the discovery of novel leads for herbal drug development.


2001 ◽  
Vol 1 ◽  
pp. 498-509 ◽  
Author(s):  
E. Roland Menzel

Photoluminescence detection of latent fingerprints has over the last quarter century brought about a new level of fingerprint detection sensitivity. The current state of the art is briefly reviewed to set the stage for upcoming new fingerprint processing strategies. These are designed for suppression of background fluorescence from articles holding latent prints, an often serious problem. The suppression of the background involves time-resolved imaging, which is dealt with from the perspective of instrumentation as well as the design of fingerprint treatment strategies. These focus on lanthanide chelates, nanocrystals, and nanocomposites functionalized to label fingerprints.


2013 ◽  
Vol 18 (5) ◽  
pp. 147-174 ◽  
Author(s):  
Roberto Carlos Bodart Brandão ◽  
Larissa Bustamente Capucho Brandão

OBJECTIVE: The objective of the present article is to describe procedures that can be performed to achieve excellence in orthodontic treatment finishing. The content is limited to microesthetics, which comprises the concept of ideal dental dimensions and proportions (white esthetics) and its correlation with the periodontium (pink esthetics). Standards of normality are described both in their real dimensions (dental height and width), and in those effectively perceived by the observer, the virtual dimensions. METHODS: The best scientific evidence was sought in the literature to support the clinical procedures that must guide the professional to obtain maximum esthetic quality on their treatments. Therefore, it is necessary to investigate what the other specialties in Dentistry expect from Orthodontics and, specially, what they have to offer. Clinical cases will be used to illustrate the dental movement that might maximize treatment outcome and to confront the ideal standards with the current state of the art. CONCLUSION: Treatment quality is directly related to the amount of procedures implemented by the orthodontist, associated with concepts and resources from Periodontics and Dental Prosthesis. Microesthetics cannot be seen in isolation, but rather as the key to establish a pleasant smile (miniesthetics) in addition to a harmonious face (macroesthetics) and a human being with high self-esteem (hyper-esthetics).


1994 ◽  
Vol 98 (974) ◽  
pp. 113-126 ◽  
Author(s):  
D.E.H. Balmford

This series of lectures recalls the achievements of that outstanding pioneer of rotary wing flight Juan de la Cierva. At around the age of 23, he began to develop the concept of improved safety in flying machines, and included in his studies the concept of the helicopter. Having carried out many tests of various possible configurations, he discarded the concept of true helicopter flight as not being achievable with the then current state-of-the-art. However, he became convinced that his basic objectives of short takeoff and landing, and safe low speed flight could be achieved by replacing the wing of a conventional aircraft with an autorotating rotor.


Author(s):  
Dongyu Zhang ◽  
Minghao Zhang ◽  
Ciyuan Peng ◽  
Jason Jung ◽  
Feng Xia

Metaphor is widely used in human communication. The cohort of scholars studying metaphor in various fields is continuously growing, but very few work has been done in bibliographical analysis of metaphor research. This paper examines the advancements in metaphor research from 2000 to 2017. Using data retrieved from Microsoft Academic Graph and Web of Science, this paper makes a macro analysis of metaphor re search, and expounds the underlying patterns of its development. Taking into consideration sub-fields of metaphor research, the internal analysis of metaphor research is carried out from a micro perspective to reveal the evolution of research topics and the inherent relationships among them. This paper provides novel insights into the current state of the art of metaphor research as well as future trends in this field, which may spark new research interests in metaphor from both linguistic and interdisciplinary perspectives.


1995 ◽  
Vol 38 (5) ◽  
pp. 1126-1142 ◽  
Author(s):  
Jeffrey W. Gilger

This paper is an introduction to behavioral genetics for researchers and practioners in language development and disorders. The specific aims are to illustrate some essential concepts and to show how behavioral genetic research can be applied to the language sciences. Past genetic research on language-related traits has tended to focus on simple etiology (i.e., the heritability or familiality of language skills). The current state of the art, however, suggests that great promise lies in addressing more complex questions through behavioral genetic paradigms. In terms of future goals it is suggested that: (a) more behavioral genetic work of all types should be done—including replications and expansions of preliminary studies already in print; (b) work should focus on fine-grained, theory-based phenotypes with research designs that can address complex questions in language development; and (c) work in this area should utilize a variety of samples and methods (e.g., twin and family samples, heritability and segregation analyses, linkage and association tests, etc.).


1976 ◽  
Vol 21 (7) ◽  
pp. 497-498
Author(s):  
STANLEY GRAND

10.37236/24 ◽  
2002 ◽  
Vol 1000 ◽  
Author(s):  
A. Di Bucchianico ◽  
D. Loeb

We survey the mathematical literature on umbral calculus (otherwise known as the calculus of finite differences) from its roots in the 19th century (and earlier) as a set of “magic rules” for lowering and raising indices, through its rebirth in the 1970’s as Rota’s school set it on a firm logical foundation using operator methods, to the current state of the art with numerous generalizations and applications. The survey itself is complemented by a fairly complete bibliography (over 500 references) which we expect to update regularly.


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