scholarly journals Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype/Presentation: Research Progress and Translational Studies

2020 ◽  
Vol 10 (5) ◽  
pp. 292 ◽  
Author(s):  
Ike C. de la Peña ◽  
Michael C. Pan ◽  
Chau Giang Thai ◽  
Tamara Alisso
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Temporal Stability ◽  
Research Progress ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
High Prevalence ◽  
Translational Studies ◽  
Wistar Kyoto ◽  
Adhd Medications

Research on the predominantly inattentive attention-deficit/hyperactivity disorder (ADHD-PI) subtype/presentation is important given its high prevalence, but paradoxically it is under-recognized and undertreated. The temporal stability of the inattention symptom could impact the high worldwide prevalence of ADHD-PI. Some evidence suggests differences in the nature of attentional deficit in ADHD-PI vs. that in other subtypes. Impairments in neuropsychological, neurocognitive, and social functioning are also evident in ADHD-PI, which could be specific to the subtype (e.g., processing speed, social perception, and skills), or differ from others in severity. Neuroimaging studies have also revealed ADHD-PI-specific neuropathological abnormalities and those that are shared with other subtypes. ADHD-PI is highly comorbid with learning and internalizing (e.g., anxiety and depression) disorders. There is no solid evidence for ADHD-PI-specific genetic etiologies and differential responses of subtypes to ADHD medications. Translational studies have used the Wistar Kyoto/NCrl substrain which requires further characterizations as an ADHD-PI model. Overall, ADHD-PI research has been conducted in the context of the Diagnostic and Statistical Manual, which arguably does not conform to the widely recognized “dimensional” view of ADHD. The Research Domain Criteria has been proposed to provide a novel framework for understanding the nature of neuropsychiatric illnesses and ultimately improve their diagnosis and treatment.

Attention Deficit Hyperactivity Disorder

2021 ◽  
pp. 134-147
Author(s):  
Kirstin Painter ◽  
Maria Scannapieco
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Brain Research ◽  
Real Life ◽  
Assessment Tools ◽  
Class Discussion ◽  
Statistical Manual ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Prevalence Estimates

Chapter 9 begins with prevalence estimates for attention deficit hyperactivity disorder (ADHD). The symptoms of inattention, hyperactivity-impulsivity, and impulsivity are addressed, followed by descriptions of how these symptoms present in children and adolescents. An overview of the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for diagnosing ADHD is presented. The chapter includes a discussion of the causes of ADHD and current research, with a focus on possible linkages between ADHD and biological, genetic, environmental, and nutritional causes and current brain research. Diagnosing youth using DSM criteria along with differentiating ADHD and other disorders is discussed. Common assessment tools used to screen for symptoms of ADHD are presented. Chapter 9 ends with two real-life case studies and questions for class discussion.

High prevalence of attention‐deficit/hyperactivity disorder in adolescents with severe obesity seeking bariatric surgery

2019 ◽  
Vol 109 (3) ◽  
pp. 581-586 ◽  
Author(s):  
Shiran Leib ◽  
Tal Gilon Mann ◽  
Daniel Stein ◽  
Irena Vusiker ◽  
Itay Tokatly Latzer ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Severe Obesity ◽  
Hyperactivity Disorder ◽  
High Prevalence

Holly's Story: Illustration of an Attention Deficit Hyperactivity Disorder Case

2008 ◽  
Vol 21 (4) ◽  
pp. 1049-1051
Author(s):  
A. Aureli ◽  
D. Piancatelli ◽  
T. Del Beato ◽  
P. Sebastiani ◽  
V. Melillo ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Neuropsychological Tests ◽  
Hla Class I ◽  
Statistical Manual ◽  
Adhd Diagnosis ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Allele Drb1

During the last 10 years a significant increase of childhood neuropsychiatric disorders, such as attention deficit hyperactivity disorder (ADHD), has been reported. ADHD is believed to have a multifactorial etiology including multiple genetic and prenatal environmental factors. For this reason, there has been a recent revival regarding the role of autoimmunity in this pathology. An ADHD combined-type patient born from a drug-addicted mother was studied. Neuropsychological tests according to the criteria of the 4th edition of the Diagnostic and Statistical Manual (DSM4) permitted us to make the ADHD-diagnosis. The HLA-A, -B, and -DRB1 alleles of the child were determined by sequence-based typing (SBT) after DNA extraction. Although no autistic behavioral features were observed in the patient, a double genetic association between ADHD and autism was reported. In fact, HLA class I alleles (A*02 and B*44) associated to autism and the HLA class II allele (DRB1*04) associated both to autism and ADHD were identified.

Attention Deficit/Hyperactivity Disorder: Diagnosis and Stereotypy

2015 ◽  
Vol 17 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Stewart Justman
Keyword(s):  
United States ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Attention Deficit Disorder ◽  
Sense Of Self ◽  
The United States ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Relative Rarity ◽  
Under Construction

The official symptoms of attention deficit disorder and attention deficit/hyperactivity disorder (ADHD) as first codified in the 3rd edition of the Diagnostic and Statistical Manual of Mental Disorders bear an uneasy resemblance to potent caricatures of Blacks that had long been in circulation in the United States. In effect, traits such as laziness and troublesomeness persistently associated with Blacks became symptoms that could be had by anyone, Black, White, or other. But just as racial imagery plays on stereotypes, the ADHD diagnosis itself has become a stereotype. Only stereotyped figures have the telltale marks of identity that children with ADHD are said to have. As we have known at least since the time of the prejudice studies cited by the United States Supreme Court in 1954, stereotypes can be highly injurious, especially if they are internalized by their objects. Children who grow with the diagnosis of ADHD, incorporating it into their sense of self even while it is under construction, may well internalize its messages. That in turn may have something to do with the dismal long-term outcomes of ADHD despite the relative rarity of severe cases.

scholarly journals Natural Product-Derived Treatments for Attention-Deficit/Hyperactivity Disorder: Safety, Efficacy, and Therapeutic Potential of Combination Therapy

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
James Ahn ◽  
Hyung Seok Ahn ◽  
Jae Hoon Cheong ◽  
Ike dela Peña
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Natural Product ◽  
Attention Deficit ◽  
Clinical Studies ◽  
Therapeutic Potential ◽  
Nutritional Supplements ◽  
Adjunct Treatment ◽  
Hyperactivity Disorder ◽  
Typical Treatment ◽  
Adhd Medications

Typical treatment plans for attention-deficit/hyperactivity disorder (ADHD) utilize nonpharmacological (behavioral/psychosocial) and/or pharmacological interventions. Limited accessibility to behavioral therapies and concerns over adverse effects of pharmacological treatments prompted research for alternative ADHD therapies such as natural product-derived treatments and nutritional supplements. In this study, we reviewed the herbal preparations and nutritional supplements evaluated in clinical studies as potential ADHD treatments and discussed their performance with regard to safety and efficacy in clinical trials. We also discussed some evidence suggesting that adjunct treatment of these agents (with another botanical agent or pharmacological ADHD treatments) may be a promising approach to treat ADHD. The analysis indicated mixed findings with regard to efficacy of natural product-derived ADHD interventions. Nevertheless, these treatments were considered as a “safer” approach than conventional ADHD medications. More comprehensive and appropriately controlled clinical studies are required to fully ascertain efficacy and safety of natural product-derived ADHD treatments. Studies that replicate encouraging findings on the efficacy of combining botanical agents and nutritional supplements with other natural product-derived therapies and widely used ADHD medications are also warranted. In conclusion, the risk-benefit balance of natural product-derived ADHD treatments should be carefully monitored when used as standalone treatment or when combined with other conventional ADHD treatments.

Z-Score LORETA Neurofeedback as a Potential Therapy for ADHD

Biofeedback ◽  
2014 ◽  
Vol 42 (2) ◽  
pp. 74-81 ◽  
Author(s):  
J. Lucas Koberda ◽  
Paula Koberda ◽  
Andrew Moses ◽  
Jessica Winslow ◽  
Andrew Bienkiewicz ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Work Performance ◽  
Therapeutic Modality ◽  
Cingulate Gyrus ◽  
Z Score ◽  
Hyperactivity Disorder ◽  
High Prevalence ◽  
The Brain ◽  
Poor School

Attention deficit hyperactivity disorder (ADHD) is a disorder of relatively high prevalence and frequently contributes to poor school and work performance. Neurofeedback (NFB) has proven to be an effective therapeutic modality in the treatment of ADHD. Recently introduced z-score LORETA neurofeedback offers promise as a tool, and appears to provide a more efficient therapy than standard two-channel neurofeedback. This advantage is based on the ability to train 19 channels simultaneously, and the ability to directly target an electrically dysregulated area of the brain, which may be more difficult to access with standard neurofeedback therapy (areas addressed with LORETA neurofeedback include the cingulate gyrus and hippocampal structures). This paper presents our experience with Z-score LORETA neurofeedback in the treatment of ADHD.

scholarly journals Sleep Microstructure Is Not Altered in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)

2012 ◽  
pp. 125-133 ◽  
Author(s):  
I. PŘÍHODOVÁ ◽  
I. PACLT ◽  
D. KEMLINK ◽  
S. NEVŠÍMALOVÁ
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Sleep Disturbances ◽  
High Rate ◽  
Adhd Group ◽  
Statistical Manual ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv ◽  
Sleep Microstructure

The high rate of occurrence of sleep disturbances in children with attention-deficit/hyperactivity disorder (ADHD) prompted the idea that structural and neurotransmitter changes might give rise to specific sleep pattern abnormalities. The aim of this study was to evaluate the microstructure of sleep in children with ADHD who had no polysomnographically diagnosed sleep disorder, had never been treated for ADHD, and were free from any psychiatric comorbidity. Participants were 14 patients with ADHD (12 boys and 2 girls aged 7-12 years, mean age 9.6±1.6). ADHD was diagnosed according to DSM-IV criteria (Diagnostic and statistical manual of mental disorders). Psychiatric comorbidities were ruled out by detailed psychiatric examination. The patients underwent two consecutive overnight video-polysomnographic (PSG) recordings, with the sleep microstructure (cyclic alternating pattern – CAP) scoring during the second night. The data were compared with age- and sex-matched controls. Sleep microstructure analysis using CAP revealed no significant differences between the ADHD group and the controls in any of the parameters under study. In conclusions, no ADHD-specific alterations were found in the sleep microstructure.

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