scholarly journals Focality of the Induced E-Field Is a Contributing Factor in the Choice of TMS Parameters: Evidence from a 3D Computational Model of the Human Brain

2020 ◽  
Vol 10 (12) ◽  
pp. 1010
Author(s):  
Deepika Konakanchi ◽  
Amy L. de Jongh Curry ◽  
Robert S. Waters ◽  
Shalini Narayana

Transcranial magnetic stimulation (TMS) is a promising, non-invasive approach in the diagnosis and treatment of several neurological conditions. However, the specific results in the cortex of the magnitude and spatial distribution of the secondary electrical field (E-field) resulting from TMS at different stimulation sites/orientations and varied TMS parameters are not clearly understood. The objective of this study is to identify the impact of TMS stimulation site and coil orientation on the induced E-field, including spatial distribution and the volume of activation in the cortex across brain areas, and hence demonstrate the need for customized optimization, using a three-dimensional finite element model (FEM). A considerable difference was noted in E-field values and distribution at different brain areas. We observed that the volume of activated cortex varied from 3000 to 7000 mm3 between the selected nine clinically relevant coil locations. Coil orientation also changed the induced E-field by a maximum of 10%, and we noted the least optimal values at the standard coil orientation pointing to the nose. The volume of gray matter activated varied by 10% on average between stimulation sites in homologous brain areas in the two hemispheres of the brain. This FEM simulation model clearly demonstrates the importance of TMS parameters for optimal results in clinically relevant brain areas. The results show that TMS parameters cannot be interchangeably used between individuals, hemispheres, and brain areas. The focality of the TMS induced E-field along with its optimal magnitude should be considered as critical TMS parameters that should be individually optimized.

2012 ◽  
Vol 192 ◽  
pp. 29-36
Author(s):  
Yu Xin Wang ◽  
Qing Chun Wang ◽  
Jian Rong Fu ◽  
Hong Hai Qiao

Effect of hard point of the engine hood on the head injury during the vehicle-human collision was studied to improve the design of engine hood. Firstly, the current common model of the engine hood was established with three-dimensional finite element modeling software, and 20 areas were divided, also a standard head finite element model was imported, secondly, each area of the engine hood was clashed by the standard head model, then the impact on the head injure was analyzed and the hard point of the hood area was achieved, thirdly, the optimization of the inside and outside panel materials and the plate structure were carried out to reduce the head damage. The simulation results show that the engine hood after optimization gave less damage to the head, which means the research carried out here is of a good reference to the engine hood optimization design for human protection


2014 ◽  
Vol 1003 ◽  
pp. 78-84
Author(s):  
Xiao Ning Chen ◽  
Jin Long Zhao ◽  
Yun Sheng Zhang ◽  
Bin Zhang

Theoretical deducing, simulated lightning test and finite element simulation are used to research the mechanism and state of lightning damage of the aircraft composites sandwich panels. It provides the basis for the design of the aircraft lightning protection. The three-dimensional finite element model of the composites panel is constructed through the thermal electrical-mechanical multi-Physics coupling field. According to the structure and the role process, the lightning effect of the aircraft composites is analysed to study the damage mechanism and the possible state of the composites panel that is struck by lightning. The impact current generator is used to carry out the simulated lightning test to observe the lightning effect of the composites panel. By comparing the results of the test and the simulation, the effectiveness and the correctness of the simulation are verified.


Author(s):  
Omar Awad ◽  
Yahia M. Al-Smadi

Boxing or martial arts are games where players chests are subject to lateral impact, the impact loads travel through skin, ribs, mediastinum (i.e. a thoracic compartment) and then through the skeleton to the rest of the body. When thorax is subject to lateral force exceeding the elastic limit of thoracic compartment, players often go in shock demanding prompt resuscitation. This paper investigates the thorax response of boxer being subject to lateral impact followed by Cardiopulmonary resuscitation (CPR). Due to complexity of thorax structure and materials, three dimensional finite element model in ANSYS was created to perform the computational biomechanical analysis of two-stage loading (i.e. lateral impact load and CPR forces). Model input parameters such as material, loading and boundary conditions have been defined. Post processing values such as deformations and stresses have been presented.


Author(s):  
JY Shih ◽  
H Hemida ◽  
E Stewart ◽  
C Roberts

Train run-throughs on railway switches is a special issue, where a train passes through non-trailable railway switches in the wrong direction. This has the potential to cause severe damage and can lead to derailment. In order to understand the impact of train run-throughs on railway switches, a three-dimensional finite element model using explicit analysis has been developed. A detailed switch model has been developed that includes all key components: stretcher bars, supplementary drive and point operating equipment. The model was validated through a specifically designed experiment where switch run-throughs were emulated on a real switch; a good agreement was found between the experimental data and the model. The model has been used to make an assessment of the locking mechanisms. The forces in each component have been assessed and investigated, and the observations of failure location and component during run-through analysis are indicated. During a run-through, the supplementary drive rod and stretcher bar encounter a significant plastic deformation, and it is recommended that they should be redesigned in order to avoid plastic behaviour.


2007 ◽  
Vol 35 (3) ◽  
pp. 226-238 ◽  
Author(s):  
K. M. Jeong ◽  
K. W. Kim ◽  
H. G. Beom ◽  
J. U. Park

Abstract The effects of variations in stiffness and geometry on the nonuniformity of tires are investigated by using the finite element analysis. In order to evaluate tire uniformity, a three-dimensional finite element model of the tire with imperfections is developed. This paper considers how imperfections, such as variations in stiffness or geometry and run-out, contribute to detrimental effects on tire nonuniformity. It is found that the radial force variation of a tire with imperfections depends strongly on the geometrical variations of the tire.


2021 ◽  
Vol 11 (5) ◽  
pp. 2225
Author(s):  
Fu Wang ◽  
Guijun Shi ◽  
Wenbo Zhai ◽  
Bin Li ◽  
Chao Zhang ◽  
...  

The steel assembled support structure of a foundation pit can be assembled easily with high strength and recycling value. Steel’s performance is significantly affected by the surrounding temperature due to its temperature sensitivity. Here, a full-scale experiment was conducted to study the influence of temperature on the internal force and deformation of supporting structures, and a three-dimensional finite element model was established for comparative analysis. The test results showed that under the temperature effect, the deformation of the central retaining pile was composed of rigid rotation and flexural deformation, while the adjacent pile of central retaining pile only experienced flexural deformation. The stress on the retaining pile crown changed little, while more stress accumulated at the bottom. Compared with the crown beam and waist beam 2, the stress on waist beam 1 was significantly affected by the temperature and increased by about 0.70 MPa/°C. Meanwhile, the stress of the rigid panel was greatly affected by the temperature, increasing 78% and 82% when the temperature increased by 15 °C on rigid panel 1 and rigid panel 2, respectively. The comparative simulation results indicated that the bending moment and shear strength of pile 1 were markedly affected by the temperature, but pile 2 and pile 3 were basically stable. Lastly, as the temperature varied, waist beam 2 had the largest change in the deflection, followed by waist beam 1; the crown beam experienced the smallest change in the deflection.


2007 ◽  
Vol 129 (6) ◽  
pp. 1028-1034 ◽  
Author(s):  
Liang Wang ◽  
Sergio Felicelli

A three-dimensional finite element model was developed to predict the temperature distribution and phase transformation in deposited stainless steel 410 (SS410) during the Laser Engineered Net Shaping (LENS™) rapid fabrication process. The development of the model was carried out using the SYSWELD software package. The model calculates the evolution of temperature in the part during the fabrication of a SS410 plate. The metallurgical transformations are taken into account using the temperature-dependent material properties and the continuous cooling transformation diagram. The ferritic and martensitic transformation as well as austenitization and tempering of martensite are considered. The influence of processing parameters such as laser power and traverse speed on the phase transformation and the consequent hardness are analyzed. The potential presence of porosity due to lack of fusion is also discussed. The results show that the temperature distribution, the microstructure, and hardness in the final part depend significantly on the processing parameters.


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