scholarly journals Prediction of Colon Cancer Stages and Survival Period with Machine Learning Approach

Cancers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2007 ◽  
Author(s):  
Pushpanjali Gupta ◽  
Sum-Fu Chiang ◽  
Prasan Kumar Sahoo ◽  
Suvendu Kumar Mohapatra ◽  
Jeng-Fu You ◽  
...  
Keyword(s):  
Machine Learning ◽  
Colon Cancer ◽  
Random Forest ◽  
Area Under The Curve ◽  
Disease Free Survival ◽  
Tumor Stage ◽  
Tnm Staging ◽  
Chang Gung Memorial Hospital ◽  
Aggression Score ◽  
Machine Learning Approach

The prediction of tumor in the TNM staging (tumor, node, and metastasis) stage of colon cancer using the most influential histopathology parameters and to predict the five years disease-free survival (DFS) period using machine learning (ML) in clinical research have been studied here. From the colorectal cancer (CRC) registry of Chang Gung Memorial Hospital, Linkou, Taiwan, 4021 patients were selected for the analysis. Various ML algorithms were applied for the tumor stage prediction of the colon cancer by considering the Tumor Aggression Score (TAS) as a prognostic factor. Performances of different ML algorithms were evaluated using five-fold cross-validation, which is an effective way of the model validation. The accuracy achieved by the algorithms taking both cases of standard TNM staging and TNM staging with the Tumor Aggression Score was determined. It was observed that the Random Forest model achieved an F-measure of 0.89, when the Tumor Aggression Score was considered as an attribute along with the standard attributes normally used for the TNM stage prediction. We also found that the Random Forest algorithm outperformed all other algorithms, with an accuracy of approximately 84% and an area under the curve (AUC) of 0.82 ± 0.10 for predicting the five years DFS.

scholarly journals Machine-learning and statistical methods for DDoS attack detection and defense system in software defined networks

2021 ◽  
Author(s):  
Merlin James Rukshan Dennis
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Statistical Approach ◽  
Denial Of Service ◽  
Attack Detection ◽  
Learning Approach ◽  
Ddos Attack ◽  
Machine Learning Approach ◽  
Ddos Detection ◽  
Ddos Attack Detection

Distributed Denial of Service (DDoS) attack is a serious threat on today’s Internet. As the traffic across the Internet increases day by day, it is a challenge to distinguish between legitimate and malicious traffic. This thesis proposes two different approaches to build an efficient DDoS attack detection system in the Software Defined Networking environment. SDN is the latest networking approach which implements centralized controller, which is programmable. The central control and the programming capability of the controller are used in this thesis to implement the detection and mitigation mechanisms. In this thesis, two designed approaches, statistical approach and machine-learning approach, are proposed for the DDoS detection. The statistical approach implements entropy computation and flow statistics analysis. It uses the mean and standard deviation of destination entropy, new flow arrival rate, packets per flow and flow duration to compute various thresholds. These thresholds are then used to distinguish normal and attack traffic. The machine learning approach uses Random Forest classifier to detect the DDoS attack. We fine-tune the Random Forest algorithm to make it more accurate in DDoS detection. In particular, we introduce the weighted voting instead of the standard majority voting to improve the accuracy. Our result shows that the proposed machine-learning approach outperforms the statistical approach. Furthermore, it also outperforms other machine-learning approach found in the literature.

scholarly journals Modeling of apartment prices in a Colombian context from a machine learning approach with stable-important attributes

DYNA ◽  
2020 ◽  
Vol 87 (212) ◽  
pp. 63-72
Author(s):  
Jorge Iván Pérez Rave ◽  
Favián González Echavarría ◽  
Juan Carlos Correa Morales
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Learning Approach ◽  
Predictive Capability ◽  
Predictive Capacity ◽  
Machine Learning Model ◽  
Machine Learning Approach ◽  
Property Price ◽  
Object Of Study ◽  
Online Pricing

The objective of this work is to develop a machine learning model for online pricing of apartments in a Colombian context. This article addresses three aspects: i) it compares the predictive capacity of linear regression, regression trees, random forest and bagging; ii) it studies the effect of a group of text attributes on the predictive capability of the models; and iii) it identifies the more stable-important attributes and interprets them from an inferential perspective to better understand the object of study. The sample consists of 15,177 observations of real estate. The methods of assembly (random forest and bagging) show predictive superiority with respect to others. The attributes derived from the text had a significant relationship with the property price (on a log scale). However, their contribution to the predictive capacity was almost nil, since four different attributes achieved highly accurate predictions and remained stable when the sample change.

scholarly journals Metabolomic Approach for Discrimination of Cultivation Age and Ripening Stage in Ginseng Berry Using Gas Chromatography-Mass Spectrometry

Molecules ◽  
2019 ◽  
Vol 24 (21) ◽  
pp. 3837 ◽  
Author(s):  
Seong-Eun Park ◽  
Seung-Ho Seo ◽  
Eun-Ju Kim ◽  
Dae-Hun Park ◽  
Kyung-Mok Park ◽  
...  
Keyword(s):  
Machine Learning ◽  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Random Forest ◽  
Gas Chromatography Mass Spectrometry ◽  
Learning Approach ◽  
Ripening Stage ◽  
Ripening Stages ◽  
Machine Learning Approach ◽  
Metabolomic Approach

The purpose of this study was to analyze metabolic differences of ginseng berries according to cultivation age and ripening stage using gas chromatography-mass spectrometry (GC-MS)-based metabolomics method. Ginseng berries were harvested every week during five different ripening stages of three-year-old and four-year-old ginseng. Using identified metabolites, a random forest machine learning approach was applied to obtain predictive models for the classification of cultivation age or ripening stage. Principal component analysis (PCA) score plot showed a clear separation by ripening stage, indicating that continuous metabolic changes occurred until the fifth ripening stage. Three-year-old ginseng berries had higher levels of valine, glutamic acid, and tryptophan, but lower levels of lactic acid and galactose than four-year-old ginseng berries at fully ripened stage. Metabolic pathways affected by different cultivation age were involved in amino acid metabolism pathways. A random forest machine learning approach extracted some important metabolites for predicting cultivation age or ripening stage with low error rate. This study demonstrates that different cultivation ages or ripening stages of ginseng berry can be successfully discriminated using a GC-MS-based metabolomic approach together with random forest analysis.

scholarly journals Cholera Risk: A Machine Learning Approach Applied to Essential Climate Variables

2020 ◽  
Vol 17 (24) ◽  
pp. 9378
Author(s):  
Amy Marie Campbell ◽  
Marie-Fanny Racault ◽  
Stephen Goult ◽  
Angus Laurenson
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Land Surface ◽  
Environmental Changes ◽  
Random Forest Classifier ◽  
Sea Surface Salinity ◽  
Learning Approach ◽  
Climate Variables ◽  
Surface Salinity ◽  
Machine Learning Approach

Oceanic and coastal ecosystems have undergone complex environmental changes in recent years, amid a context of climate change. These changes are also reflected in the dynamics of water-borne diseases as some of the causative agents of these illnesses are ubiquitous in the aquatic environment and their survival rates are impacted by changes in climatic conditions. Previous studies have established strong relationships between essential climate variables and the coastal distribution and seasonal dynamics of the bacteria Vibrio cholerae, pathogenic types of which are responsible for human cholera disease. In this study we provide a novel exploration of the potential of a machine learning approach to forecast environmental cholera risk in coastal India, home to more than 200 million inhabitants, utilising atmospheric, terrestrial and oceanic satellite-derived essential climate variables. A Random Forest classifier model is developed, trained and tested on a cholera outbreak dataset over the period 2010–2018 for districts along coastal India. The random forest classifier model has an Accuracy of 0.99, an F1 Score of 0.942 and a Sensitivity score of 0.895, meaning that 89.5% of outbreaks are correctly identified. Spatio-temporal patterns emerged in terms of the model’s performance based on seasons and coastal locations. Further analysis of the specific contribution of each Essential Climate Variable to the model outputs shows that chlorophyll-a concentration, sea surface salinity and land surface temperature are the strongest predictors of the cholera outbreaks in the dataset used. The study reveals promising potential of the use of random forest classifiers and remotely-sensed essential climate variables for the development of environmental cholera-risk applications. Further exploration of the present random forest model and associated essential climate variables is encouraged on cholera surveillance datasets in other coastal areas affected by the disease to determine the model’s transferability potential and applicative value for cholera forecasting systems.

scholarly journals Predicting mortality in hemodialysis patients using machine learning analysis

2020 ◽  
Author(s):  
Victoria Garcia-Montemayor ◽  
Alejandro Martin-Malo ◽  
Carlo Barbieri ◽  
Francesco Bellocchio ◽  
Sagrario Soriano ◽  
...  
Keyword(s):  
Machine Learning ◽  
Logistic Regression ◽  
Random Forest ◽  
Prediction Models ◽  
Initial Period ◽  
Area Under The Curve ◽  
Mortality Prediction ◽  
Machine Learning Techniques ◽  
Prediction Of Mortality ◽  
Mortality Prediction Models

Abstract Background Besides the classic logistic regression analysis, non-parametric methods based on machine learning techniques such as random forest are presently used to generate predictive models. The aim of this study was to evaluate random forest mortality prediction models in haemodialysis patients. Methods Data were acquired from incident haemodialysis patients between 1995 and 2015. Prediction of mortality at 6 months, 1 year and 2 years of haemodialysis was calculated using random forest and the accuracy was compared with logistic regression. Baseline data were constructed with the information obtained during the initial period of regular haemodialysis. Aiming to increase accuracy concerning baseline information of each patient, the period of time used to collect data was set at 30, 60 and 90 days after the first haemodialysis session. Results There were 1571 incident haemodialysis patients included. The mean age was 62.3 years and the average Charlson comorbidity index was 5.99. The mortality prediction models obtained by random forest appear to be adequate in terms of accuracy [area under the curve (AUC) 0.68–0.73] and superior to logistic regression models (ΔAUC 0.007–0.046). Results indicate that both random forest and logistic regression develop mortality prediction models using different variables. Conclusions Random forest is an adequate method, and superior to logistic regression, to generate mortality prediction models in haemodialysis patients.

scholarly journals Which PHQ-9 Items Can Effectively Screen for Suicide? Machine Learning Approaches

2021 ◽  
Vol 18 (7) ◽  
pp. 3339
Author(s):  
Sunhae Kim ◽  
Hye-Kyung Lee ◽  
Kounseok Lee
Keyword(s):  
Machine Learning ◽  
Primary Care ◽  
Suicidal Ideation ◽  
Random Forest ◽  
Suicide Ideation ◽  
Area Under The Curve ◽  
Learning Approaches ◽  
K Nearest Neighbors ◽  
Predictive Values ◽  
Linear Discriminant

(1) Background: The Patient Health Questionnaire-9 (PHQ-9) is a tool that screens patients for depression in primary care settings. In this study, we evaluated the efficacy of PHQ-9 in evaluating suicidal ideation (2) Methods: A total of 8760 completed questionnaires collected from college students were analyzed. The PHQ-9 was scored in combination with and evaluated against four categories (PHQ-2, PHQ-8, PHQ-9, and PHQ-10). Suicidal ideations were evaluated using the Mini-International Neuropsychiatric Interview suicidality module. Analyses used suicide ideation as the dependent variable, and machine learning (ML) algorithms, k-nearest neighbors, linear discriminant analysis (LDA), and random forest. (3) Results: Random forest application using the nine items of the PHQ-9 revealed an excellent area under the curve with a value of 0.841, with 94.3% accuracy. The positive and negative predictive values were 84.95% (95% CI = 76.03–91.52) and 95.54% (95% CI = 94.42–96.48), respectively. (4) Conclusion: This study confirmed that ML algorithms using PHQ-9 in the primary care field are reliably accurate in screening individuals with suicidal ideation.

scholarly journals An Analytical Model for Prediction of Heart Disease using Machine Learning Classifiers

2021 ◽  
Author(s):  
Diti Roy ◽  
Md. Ashiq Mahmood ◽  
Tamal Joyti Roy
Keyword(s):  
Machine Learning ◽  
Heart Disease ◽  
Random Forest ◽  
Learning Algorithm ◽  
Modern Technology ◽  
Learning Approach ◽  
Data Sets ◽  
Machine Learning Classifiers ◽  
Machine Learning Approach ◽  
Day By Day

<p>Heart Disease is the most dominating disease which is taking a large number of deaths every year. A report from WHO in 2016 portrayed that every year at least 17 million people die of heart disease. This number is gradually increasing day by day and WHO estimated that this death toll will reach the summit of 75 million by 2030. Despite having modern technology and health care system predicting heart disease is still beyond limitations. As the Machine Learning algorithm is a vital source predicting data from available data sets we have used a machine learning approach to predict heart disease. We have collected data from the UCI repository. In our study, we have used Random Forest, Zero R, Voted Perceptron, K star classifier. We have got the best result through the Random Forest classifier with an accuracy of 97.69.<i><b></b></i></p> <p><b> </b></p>

scholarly journals The Prediction of Essential Medicines Demand: A Machine Learning Approach Using Consumption Data in Rwanda

Processes ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 26
Author(s):  
Francois Mbonyinshuti ◽  
Joseph Nkurunziza ◽  
Japhet Niyobuhungiro ◽  
Egide Kayitare
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Predictive Modeling ◽  
Essential Medicines ◽  
Complex Data ◽  
Global Business ◽  
Oral Rehydration ◽  
Consumption Data ◽  
Machine Learning Approach ◽  
And Performance

Today’s global business trends are causing a significant and complex data revolution in the healthcare industry, culminating in the use of artificial intelligence and predictive modeling to improve health outcomes and performance. The dataset, which was referred to is based on consumption data from 2015 to 2019, included approximately 500 goods. Based on a series of data pre-processing activities, the top ten (10) essential medicines most used were chosen, namely cotrimoxazole 480 mg, amoxicillin 250 mg, paracetamol 500 mg, oral rehydration salts (O.R.S) sachet 20.5 g, chlorpheniramine 4 mg, nevirapine 200 mg, aminophylline 100 mg, artemether 20 mg + lumefantrine (AL) 120 mg, Cromoglycate ophthalmic. Our study concentrated on the application of machine learning (ML) to forecast future trends in the demand for essential drugs in Rwanda. The following models were created and applied: linear regression, artificial neural network, and random forest. The random forest was able to predict 10 selected medicines with an accuracy of 88 percent with the train set and 76 percent with the test set, and it can thus be used to forecast future demand based on past consumption data by inputting a month, year, district, and medicine name. According to our findings, the random Forest model performed well as a forecasting model for the demand for essential medicines. Finally, data-driven predictive modeling with machine learning (ML) could become the cornerstone of health supply chain planning and operational management.

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