scholarly journals Which PHQ-9 Items Can Effectively Screen for Suicide? Machine Learning Approaches

Author(s):  
Sunhae Kim ◽  
Hye-Kyung Lee ◽  
Kounseok Lee

(1) Background: The Patient Health Questionnaire-9 (PHQ-9) is a tool that screens patients for depression in primary care settings. In this study, we evaluated the efficacy of PHQ-9 in evaluating suicidal ideation (2) Methods: A total of 8760 completed questionnaires collected from college students were analyzed. The PHQ-9 was scored in combination with and evaluated against four categories (PHQ-2, PHQ-8, PHQ-9, and PHQ-10). Suicidal ideations were evaluated using the Mini-International Neuropsychiatric Interview suicidality module. Analyses used suicide ideation as the dependent variable, and machine learning (ML) algorithms, k-nearest neighbors, linear discriminant analysis (LDA), and random forest. (3) Results: Random forest application using the nine items of the PHQ-9 revealed an excellent area under the curve with a value of 0.841, with 94.3% accuracy. The positive and negative predictive values were 84.95% (95% CI = 76.03–91.52) and 95.54% (95% CI = 94.42–96.48), respectively. (4) Conclusion: This study confirmed that ML algorithms using PHQ-9 in the primary care field are reliably accurate in screening individuals with suicidal ideation.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sunhae Kim ◽  
Hye-Kyung Lee ◽  
Kounseok Lee

AbstractMinnesota Multiphasic Personality Inventory-2 (MMPI-2) is a widely used tool for early detection of psychological maladjustment and assessing the level of adaptation for a large group in clinical settings, schools, and corporations. This study aims to evaluate the utility of MMPI-2 in assessing suicidal risk using the results of MMPI-2 and suicidal risk evaluation. A total of 7,824 datasets collected from college students were analyzed. The MMPI-2-Resturcutred Clinical Scales (MMPI-2-RF) and the response results for each question of the Mini International Neuropsychiatric Interview (MINI) suicidality module were used. For statistical analysis, random forest and K-Nearest Neighbors (KNN) techniques were used with suicidal ideation and suicide attempt as dependent variables and 50 MMPI-2 scale scores as predictors. On applying the random forest method to suicidal ideation and suicidal attempts, the accuracy was 92.9% and 95%, respectively, and the Area Under the Curves (AUCs) were 0.844 and 0.851, respectively. When the KNN method was applied, the accuracy was 91.6% and 94.7%, respectively, and the AUCs were 0.722 and 0.639, respectively. The study confirmed that machine learning using MMPI-2 for a large group provides reliable accuracy in classifying and predicting the subject's suicidal ideation and past suicidal attempts.


2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.


Author(s):  
Chaudhari Shraddha

Activity recognition in humans is one of the active challenges that find its application in numerous fields such as, medical health care, military, manufacturing, assistive techniques and gaming. Due to the advancements in technologies the usage of smartphones in human lives has become inevitable. The sensors in the smartphones help us to measure the essential vital parameters. These measured parameters enable us to monitor the activities of humans, which we call as human activity recognition. We have applied machine learning techniques on a publicly available dataset. K-Nearest Neighbors and Random Forest classification algorithms are applied. In this paper, we have designed and implemented an automatic human activity recognition system that independently recognizes the actions of the humans. This system is able to recognize the activities such as Laying, Sitting, Standing, Walking, Walking downstairs and Walking upstairs. The results obtained show that, the KNN and Random Forest Algorithms gives 90.22% and 92.70% respectively of overall accuracy in detecting the activities.


Author(s):  
Sheela Rani P ◽  
Dhivya S ◽  
Dharshini Priya M ◽  
Dharmila Chowdary A

Machine learning is a new analysis discipline that uses knowledge to boost learning, optimizing the training method and developing the atmosphere within which learning happens. There square measure 2 sorts of machine learning approaches like supervised and unsupervised approach that square measure accustomed extract the knowledge that helps the decision-makers in future to require correct intervention. This paper introduces an issue that influences students' tutorial performance prediction model that uses a supervised variety of machine learning algorithms like support vector machine , KNN(k-nearest neighbors), Naïve Bayes and supplying regression and logistic regression. The results supported by various algorithms are compared and it is shown that the support vector machine and Naïve Bayes performs well by achieving improved accuracy as compared to other algorithms. The final prediction model during this paper may have fairly high prediction accuracy .The objective is not just to predict future performance of students but also provide the best technique for finding the most impactful features that influence student’s while studying.


2020 ◽  
Vol 14 ◽  

Breast Cancer (BC) is amongst the most common and leading causes of deaths in women throughout the world. Recently, classification and data analysis tools are being widely used in the medical field for diagnosis, prognosis and decision making to help lower down the risks of people dying or suffering from diseases. Advanced machine learning methods have proven to give hope for patients as this has helped the doctors in early detection of diseases like Breast Cancer that can be fatal, in support with providing accurate outcomes. However, the results highly depend on the techniques used for feature selection and classification which will produce a strong machine learning model. In this paper, a performance comparison is conducted using four classifiers which are Multilayer Perceptron (MLP), Support Vector Machine (SVM), K-Nearest Neighbors (KNN) and Random Forest on the Wisconsin Breast Cancer dataset to spot the most effective predictors. The main goal is to apply best machine learning classification methods to predict the Breast Cancer as benign or malignant using terms such as accuracy, f-measure, precision and recall. Experimental results show that Random forest is proven to achieve the highest accuracy of 99.26% on this dataset and features, while SVM and KNN show 97.78% and 97.04% accuracy respectively. MLP shows the least accuracy of 94.07%. All the experiments are conducted using RStudio as the data mining tool platform.


2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 264-265
Author(s):  
Duy Ngoc Do ◽  
Guoyu Hu ◽  
Younes Miar

Abstract American mink (Neovison vison) is the major source of fur for the fur industries worldwide and Aleutian disease (AD) is causing severe financial losses to the mink industry. Different methods have been used to diagnose the AD in mink, but the combination of several methods can be the most appropriate approach for the selection of AD resilient mink. Iodine agglutination test (IAT) and counterimmunoelectrophoresis (CIEP) methods are commonly employed in test-and-remove strategy; meanwhile, enzyme-linked immunosorbent assay (ELISA) and packed-cell volume (PCV) methods are complementary. However, using multiple methods are expensive; and therefore, hindering the corrected use of AD tests in selection. This research presented the assessments of the AD classification based on machine learning algorithms. The Aleutian disease was tested on 1,830 individuals using these tests in an AD positive mink farm (Canadian Centre for Fur Animal Research, NS, Canada). The accuracy of classification for CIEP was evaluated based on the sex information, and IAT, ELISA and PCV test results implemented in seven machine learning classification algorithms (Random Forest, Artificial Neural Networks, C50Tree, Naive Bayes, Generalized Linear Models, Boost, and Linear Discriminant Analysis) using the Caret package in R. The accuracy of prediction varied among the methods. Overall, the Random Forest was the best-performing algorithm for the current dataset with an accuracy of 0.89 in the training data and 0.94 in the testing data. Our work demonstrated the utility and relative ease of using machine learning algorithms to assess the CIEP information, and consequently reducing the cost of AD tests. However, further works require the inclusion of production and reproduction information in the models and extension of phenotypic collection to increase the accuracy of current methods.


2021 ◽  
Vol 16 (2) ◽  
pp. 35-49
Author(s):  
Adamaria Perrotta ◽  
◽  
Georgios Bliatsios ◽  

Peer-to-Peer (P2P) lending is an online lending process allowing individuals to obtain or concede loans without the interference of traditional financial intermediaries. It has grown quickly the last years, with some platforms reaching billions of dollars of loans in principal in a short amount of time. Since each loan is associated with the probability of loss due to a borrower's failure, this paper addresses the borrower's default prediction problem in the P2P financial ecosystem. The main assumption, which makes this study different from the available literature, is that borrowers sharing the same homeownership status display similar risk profile, thus a model per segment should be developed. We estimate the Probability of Default (PD) of a borrower by using Logistic Regression (LR) coupled with Weight of Evidence encoding. The features set is identified via the Sequential Feature Selection (SFS). We compare the forward against the backward SFS, in terms of the Area Under the Curve (AUC), and we choose the one that maximizes this statistic. Finally, we compare the results of the chosen LR approach against two other popular Machine Learning (ML) techniques: the k Nearest Neighbors (k-NN) and the Random Forest (RF).


2019 ◽  
Vol 26 (3) ◽  
pp. 1810-1826 ◽  
Author(s):  
Behnaz Raef ◽  
Masoud Maleki ◽  
Reza Ferdousi

The aim of this study is to develop a computational prediction model for implantation outcome after an embryo transfer cycle. In this study, information of 500 patients and 1360 transferred embryos, including cleavage and blastocyst stages and fresh or frozen embryos, from April 2016 to February 2018, were collected. The dataset containing 82 attributes and a target label (indicating positive and negative implantation outcomes) was constructed. Six dominant machine learning approaches were examined based on their performance to predict embryo transfer outcomes. Also, feature selection procedures were used to identify effective predictive factors and recruited to determine the optimum number of features based on classifiers performance. The results revealed that random forest was the best classifier (accuracy = 90.40% and area under the curve = 93.74%) with optimum features based on a 10-fold cross-validation test. According to the Support Vector Machine-Feature Selection algorithm, the ideal numbers of features are 78. Follicle stimulating hormone/human menopausal gonadotropin dosage for ovarian stimulation was the most important predictive factor across all examined embryo transfer features. The proposed machine learning-based prediction model could predict embryo transfer outcome and implantation of embryos with high accuracy, before the start of an embryo transfer cycle.


2019 ◽  
Vol 11 (10) ◽  
pp. 1195 ◽  
Author(s):  
Minsang Kim ◽  
Myung-Sook Park ◽  
Jungho Im ◽  
Seonyoung Park ◽  
Myong-In Lee

This study compared detection skill for tropical cyclone (TC) formation using models based on three different machine learning (ML) algorithms-decision trees (DT), random forest (RF), and support vector machines (SVM)-and a model based on Linear Discriminant Analysis (LDA). Eight predictors were derived from WindSat satellite measurements of ocean surface wind and precipitation over the western North Pacific for 2005–2009. All of the ML approaches performed better with significantly higher hit rates ranging from 94 to 96% compared with LDA performance (~77%), although false alarm rate by MLs is slightly higher (21–28%) than that by LDA (~13%). Besides, MLs could detect TC formation at the time as early as 26–30 h before the first time diagnosed as tropical depression by the JTWC best track, which was also 5 to 9 h earlier than that by LDA. The skill differences across MLs were relatively smaller than difference between MLs and LDA. Large yearly variation in forecast lead time was common in all models due to the limitation in sampling from orbiting satellite. This study highlights that ML approaches provide an improved skill for detecting TC formation compared with conventional linear approaches.


Reports ◽  
2019 ◽  
Vol 2 (4) ◽  
pp. 26 ◽  
Author(s):  
Govind Chada

Increasing radiologist workloads and increasing primary care radiology services make it relevant to explore the use of artificial intelligence (AI) and particularly deep learning to provide diagnostic assistance to radiologists and primary care physicians in improving the quality of patient care. This study investigates new model architectures and deep transfer learning to improve the performance in detecting abnormalities of upper extremities while training with limited data. DenseNet-169, DenseNet-201, and InceptionResNetV2 deep learning models were implemented and evaluated on the humerus and finger radiographs from MURA, a large public dataset of musculoskeletal radiographs. These architectures were selected because of their high recognition accuracy in a benchmark study. The DenseNet-201 and InceptionResNetV2 models, employing deep transfer learning to optimize training on limited data, detected abnormalities in the humerus radiographs with 95% CI accuracies of 83–92% and high sensitivities greater than 0.9, allowing for these models to serve as useful initial screening tools to prioritize studies for expedited review. The performance in the case of finger radiographs was not as promising, possibly due to the limitations of large inter-radiologist variation. It is suggested that the causes of this variation be further explored using machine learning approaches, which may lead to appropriate remediation.


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