Orthodontic Treatment of a Patient with Dentin Dysplasia Type I and Bilateral Maxillary Canine Impaction: Case Presentation and a Family-Based Genetic Analysis

Dentin dysplasia is a rare hereditary disorder, transmitted by autosomal dominant mode, affecting both dentin and pulp. In Type I crown morphology is normal, but root dentin organization loss leads to shorter roots. Mutations in the SSUH2, VPS4B and SMOC2 genes have been reported as responsible for this condition. Orthodontic treatment was conducted on an 11-year-old female patient presenting the disorder along with bilaterally impacted permanent maxillary canines, in close proximity to the roots of the lateral and central incisors. Treatment plan included lateral incisors extraction, surgical exposure and traction of the impacted canines. Light forces were applied from a custom-made trans-palatal arch. Comprehensive orthodontic treatment was performed using edgewise appliances. After 3 years and 2 months, group function occlusion was achieved. The canines underwent composite resin restorations. At one year post-retention, the dentition remained stable. Family-based genetic analysis did not reveal any mutations in the aforementioned genes pointing to further genetic heterogeneity of this disorder. As dental medicine becomes more sophisticated and personalized, the association between mutation type/function and orthodontic treatment response may provide useful therapeutic insights. The positive treatment response of the presented case could be attributed to a more “benign” mutation awaiting to be identified.

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Useful design of custom-made mouthguard for athletes undergoing orthodontic treatment with brackets and wires

Journal of Dental Sciences ◽

10.1016/j.jds.2021.03.010 ◽

2021 ◽

Author(s):

Ruman Uddin Chowdhury ◽

Hiroshi Churei ◽

Gen Tanabe ◽

Yuriko Yoshida ◽

Kairi Hayashi ◽

...

Keyword(s):

Orthodontic Treatment ◽

Custom Made

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Acute Type A Aortic Dissection Treated Using a Tubular Stent-Graft in the Ascending Aorta and a Multibranched Stent-Graft in the Aortic Arch

Journal of Endovascular Therapy ◽

10.1177/1526602816680089 ◽

2016 ◽

Vol 24 (1) ◽

pp. 75-80 ◽

Cited By ~ 17

Author(s):

Tilo Kölbel ◽

Christian Detter ◽

Sebastian W. Carpenter ◽

Fiona Rohlffs ◽

Yskert von Kodolitsch ◽

...

Keyword(s):

Aortic Dissection ◽

Stent Graft ◽

Open Surgery ◽

Type A ◽

Ascending Aorta ◽

Type I ◽

Acute Type ◽

Stent Grafts ◽

Type A Aortic Dissection ◽

Custom Made

Purpose: To describe the combined use of a tubular stent-graft for the ascending aorta and an inner-branched arch stent-graft for patients with acute type A aortic dissection. Technique: The technique to deploy these modular, custom-made stent-grafts is demonstrated in 2 patients with acute DeBakey type I aortic dissections and significant comorbidities precluding open surgery. Both emergent procedures were made possible by the availability of suitable devices manufactured for elective repair in other patients. After preliminary carotid-subclavian bypass, a long Lunderquist guidewire was introduced from the right femoral artery to the left ventricle for delivery of the Zenith Ascend and Zenith Branched Arch Endovascular Grafts under inflow occlusion. Bridging stent-grafts were delivered to the innominate and left common carotid arteries to connect to the 2 inner branches; the left subclavian artery was occluded. Both cases were technically successful and resulted in exclusion of the false lumen in the ascending aorta. The operating and fluoroscopy times did not exceed those of comparable elective procedures. The patients were rapidly extubated shortly after the procedure and without serious immediate complications. One patient survived 11 months with a satisfactory repair; the other succumbed to complications of recurrent pneumonia after 23 days. Conclusion: Endovascular treatment of patients with acute type A aortic dissection using a combination of tubular and branched stent-grafts in the ascending aorta is feasible and offers an alternative strategy to open surgery.

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Clinical value of classification of venous malformations with contrast-enhanced MR Angiography

Phlebology The Journal of Venous Disease ◽

10.1177/0268355516682861 ◽

2016 ◽

Vol 32 (9) ◽

pp. 628-633 ◽

Cited By ~ 8

Author(s):

Ahmed Abdel Khalek Abdel Razek ◽

Germeen Ashmalla Albair ◽

Sieza Samir

Keyword(s):

Mr Angiography ◽

Treatment Plan ◽

Venous Malformation ◽

Observer Agreement ◽

Type I ◽

Venous Malformations ◽

Single Measure ◽

Intra Class Correlation ◽

Contrast Enhanced

Aim To classify venous malformations based on contrast-enhanced MR angiography that may serve as a basis for treatment plan. Patients and methods A retrospective analysis was performed in 58 patients with venous malformations who underwent contrast-enhanced MR angiography. Venous malformations were classified according to their venous drainage into: type I, isolated malformation without peripheral drainage; type II, malformation that drains into normal veins; type III, malformation that drains into dilated veins; and type IV, malformation that represents dysplastic venous ectasia. Image analysis was done by two reviewers. Intra and inter-observer agreement of both reviewers and intra-class correlation was done. Results The intra-observer agreement of contrast-enhanced MR angiography classification of venous malformations was excellent for the first reviewer ( k = 0.83, 95% CI = 0.724–0.951, P = 0.001) and substantial for the second reviewer ( K = 0.79, 95% CI = 0.656-0.931, P = 0.001). The inter-observer agreement of contrast-enhanced MR angiography classification of venous malformations was excellent for both reviewers at the first time ( K = 0.96, 95% CI = 0.933–1.000, P = 0.001) and second time ( k = 0.81, 95% CI = 0.678–0.942, P = 0.001). There was high intra-class correlation of both reviewers for single measure ( ICC = 0.85, 95% CI = 0.776–0.918, P = 0.001) and for average measures ( ICC = 0.96, 95% CI = 0.933–0.978, P = 0.001). Conclusion Contrast-enhanced MR angiography classification of venous malformations may be a useful, simple and reliable tool to accurately classify venous malformation and this topographic classification helps for better management strategy.

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Genetic Analysis and Molecular Phylogeny of Simian T-Cell Lymphotropic Virus Type I: Evidence for Independent Virus Evolution in Asia and Africa

Virology ◽

10.1006/viro.1994.1097 ◽

1994 ◽

Vol 199 (1) ◽

pp. 56-66 ◽

Cited By ~ 49

Author(s):

Ki-Joon Song ◽

Vivek R. Nerurkar ◽

Naruya Saitou ◽

Aristides Lazo ◽

James R. Blakeslee ◽

...

Keyword(s):

T Cell ◽

Molecular Phylogeny ◽

Genetic Analysis ◽

Virus Type ◽

Virus Evolution ◽

Type I

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Treatment of a type Ia endoleak following EVAR using a custom-made inner branch device.

Vascular ◽

10.1177/17085381211062743 ◽

2021 ◽

pp. 170853812110627

Author(s):

Gino Gemayel GG ◽

Michel Montessuit MM ◽

Anouche Gemayel GA

Keyword(s):

Abdominal Aortic Aneurysm ◽

Open Surgery ◽

Type I ◽

Novel Technology ◽

Abdominal Aortic ◽

Custom Made ◽

Type Ia ◽

Type I Endoleak ◽

Aortic Cuff

Objectives We represent two cases of late proximal type I endoleak following EVAR with aneurysm expansion that were treated with a custom-made graft with inner branches. Methods Two patients of 87 and 82 years old were operated by EVAR 6 and 8 years ago for abdominal aortic aneurysm. Both had proximal type I endoleak with aneurysm sac expansion. Open surgery had a high risk, and a proximal aortic extension with a simple aortic cuff was not possible neither because previous EVAR grafts were already at the level of the renal arteries. A custom-made endograft with inner branches was planned as a fenestrated graft was not technically possible. Results We successfully treated both patients using a custom-made graft with four inner branches from Jotec (Cryolife, Kennesaw, GA). Three months’ follow-up CT scan did not show any endoleaks. All target vessels were patent with good conformability of the bridging stents. Conclusion The treatment of proximal type I endoleak using inner branches’ endografts is feasible. This novel technology might broaden the indications for complex aortic repair in a group of patients where fenestrated endografts are not possible.

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Orthodontic Conundrums Part 3: Indications for the loss of a lower incisor

Orthodontic Update ◽

10.12968/ortu.2021.14.2.72 ◽

2021 ◽

Vol 14 (2) ◽

pp. 72-79

Author(s):

Naeem I Adam ◽

Minnie Lyons-Coleman ◽

Adam Jowett ◽

Trevor Hodge

Keyword(s):

Clinical Relevance ◽

Orthodontic Treatment ◽

Treatment Plan ◽

Clinical Scenario ◽

Lower Incisor ◽

Highly Effective ◽

Extraction Pattern ◽

Final Article ◽

Dental Professionals

The final article in our series on orthodontic conundrums considers the extraction of a single lower incisor as part of a wider orthodontic treatment plan. This is a relatively uncommon approach; however, when used in the appropriate clinical scenario, it can be highly effective. Extraction of a lower incisor may be required to provide space for alignment of the teeth and serve as a pragmatic way to facilitate treatment while preserving posterior units. This article explores some of the possible orthodontic indications and contraindications for extraction of a lower incisor. CPD/Clinical Relevance: In certain clinical situations, extraction of a lower incisor has significant advantages. Dental professionals should be aware of this extraction pattern and its limitations.

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First Genetic Analysis of Lattice Corneal Dystrophy Type I in a Family from Bulgaria

European Journal of Ophthalmology ◽

10.1177/112067210501500624 ◽

2005 ◽

Vol 15 (6) ◽

pp. 804-808 ◽

Cited By ~ 1

Author(s):

E. Capoluongo ◽

G. De benedetti ◽

P. Concolino ◽

M. Sepe ◽

R. Ambu ◽

...

Keyword(s):

Genetic Analysis ◽

Corneal Dystrophy ◽

Type I ◽

Lattice Corneal Dystrophy

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Relationship between Orthodontic Treatment Plan and Goslon Yardstick Assessment in Japanese Patients with Unilateral Cleft Lip and Palate: One-stage vs. Two-stage Palatoplasty

The Bulletin of Tokyo Dental College ◽

10.2209/tdcpublication.2016-0700 ◽

2016 ◽

Vol 57 (3) ◽

pp. 159-168

Author(s):

Takenobu Ishii ◽

Teruo Sakamoto ◽

Munetada Ishikawa ◽

Toshihiko Yasumura ◽

Haruyo Miyazaki ◽

...

Keyword(s):

Orthodontic Treatment ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Treatment Plan ◽

Japanese Patients ◽

Two Stage ◽

One Stage

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An Innovative Lingual Retainer Wire Stabilizer

The Journal of Indian Orthodontic Society ◽

10.1177/0301574220941492 ◽

2020 ◽

Vol 54 (4) ◽

pp. 382-383

Author(s):

Tivanani Venkata Durga Mahendra ◽

Vyshnavi Mulakala

Keyword(s):

Orthodontic Treatment ◽

Soft Tissues ◽

Critical Step ◽

Stable Position ◽

Custom Made ◽

Iatrogenic Damage ◽

Lingual Retainer

One of the means of maintaining the incisor alignment after orthodontic treatment is by fixed lingual retainer. Over the decade’s various techniques have been advocated for bonding a lingual retainer wire. The most critical step to the orthodontist is stabilization of retainer wire in its stable position to prevent relapse. The purpose of this study is to introduce a custom-made device which is easy to fabricate and stabilizes the retainer wire to the contours of the palatal surface of the teeth without causing any iatrogenic damage to the adjacent soft tissues while bonding.

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