Surface Modification of Biomedical Titanium Alloy: Micromorphology, Microstructure Evolution and Biomedical Applications

With the increasing demand for bone implant therapy, titanium alloy has been widely used in the biomedical field. However, various potential applications of titanium alloy implants are easily hampered by their biological inertia. In fact, the interaction of the implant with tissue is critical to the success of the implant. Thus, the implant surface is modified before implantation frequently, which can not only improve the mechanical properties of the implant, but also polish up bioactivity and osseoconductivity on a cellular level. This paper aims at reviewing titanium surface modification techniques for biomedical applications. Additionally, several other significant aspects are described in detail in this article, for example, micromorphology, microstructure evolution that determines mechanical properties, as well as a number of issues concerning about practical application of biomedical implants.

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Bioactive Surface Modification of Newly Developed β-Type Titanium Alloy for Biomedical Applications by Electrochemical Treatment

Journal of the Japan Institute of Metals and Materials ◽

10.2320/jinstmet.70.304 ◽

2006 ◽

Vol 70 (4) ◽

pp. 304-313

Author(s):

Mitsuo Niinomi ◽

Toshikazu Akahori ◽

Hiroyuki Toda ◽

Daisuke Iizuka ◽

Hisao Fukui ◽

...

Keyword(s):

Titanium Alloy ◽

Surface Modification ◽

Biomedical Applications ◽

Electrochemical Treatment ◽

Bioactive Surface Modification

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Deformation-induced variations in microstructure evolution and mechanical properties of bi-modal Ti-55511 titanium alloy

Journal of Alloys and Compounds ◽

10.1016/j.jallcom.2018.12.262 ◽

2019 ◽

Vol 783 ◽

pp. 709-717 ◽

Cited By ~ 21

Author(s):

Wei Chen ◽

Chao Li ◽

Xiaoyong Zhang ◽

Chao Chen ◽

Y.C. Lin ◽

...

Keyword(s):

Mechanical Properties ◽

Titanium Alloy ◽

Microstructure Evolution

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Surface Modification of Bacterial Cellulose for Biomedical Applications

International Journal of Molecular Sciences ◽

10.3390/ijms23020610 ◽

2022 ◽

Vol 23 (2) ◽

pp. 610

Author(s):

Teresa Aditya ◽

Jean Paul Allain ◽

Camilo Jaramillo ◽

Andrea Mesa Restrepo

Keyword(s):

Mechanical Properties ◽

Drug Delivery ◽

Tissue Engineering ◽

Surface Modification ◽

Bacterial Cellulose ◽

Biomedical Applications ◽

Human Tissues ◽

Naturally Occurring ◽

Microstructure And Mechanical Properties

Bacterial cellulose is a naturally occurring polysaccharide with numerous biomedical applications that range from drug delivery platforms to tissue engineering strategies. BC possesses remarkable biocompatibility, microstructure, and mechanical properties that resemble native human tissues, making it suitable for the replacement of damaged or injured tissues. In this review, we will discuss the structure and mechanical properties of the BC and summarize the techniques used to characterize these properties. We will also discuss the functionalization of BC to yield nanocomposites and the surface modification of BC by plasma and irradiation-based methods to fabricate materials with improved functionalities such as bactericidal capabilities.

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Electrophoretic Deposition of Carbon Nanotubes over TiO2Nanotubes: Evaluation of Surface Properties and Biocompatibility

Bioinorganic Chemistry and Applications ◽

10.1155/2014/236521 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 7

Author(s):

Jung Eun Park ◽

Il Song Park ◽

Tae Sung Bae ◽

Min Ho Lee

Keyword(s):

Mechanical Properties ◽

Carbon Nanotubes ◽

Corrosion Resistance ◽

Surface Modification ◽

Electrophoretic Deposition ◽

Biomedical Applications ◽

Controlled Drug Delivery ◽

Chemical Durability ◽

Surface Modified ◽

Excellent Chemical

Titanium (Ti) is often used as an orthopedic and dental implant material due to its better mechanical properties, corrosion resistance, and excellent biocompatibility. Formation of TiO2nanotubes (TiO2NTs) on titanium is an interesting surface modification to achieve controlled drug delivery and to promote cell growth. Carbon nanotubes (CNTs) possess excellent chemical durability and mechanical strength. The use of CNTs in biomedical applications such as scaffolds has received considerable attention in recent years. The present study aims to modify the surface of titanium by anodizing to form TiO2NTs and subsequently deposit CNTs over it by electrophoretic deposition (EPD). Characteristic, biocompatibility, and apatite forming ability of the surface modified samples were evaluated. The results of the study reveal that CNTs coating on TiO2nanotubes help improve the biological activity and this type of surface modification is highly suitable for biomedical applications.

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