scholarly journals Safety and Design Aspects of Powered Toothbrush—A Narrative Review

2020 ◽  
Vol 8 (1) ◽  
pp. 15
Author(s):  
Clarence Ng ◽  
James Kit Hon Tsoi ◽  
Edward C. M. Lo ◽  
Jukka P. Matinlinna
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Narrative Review ◽  
Metal Parts ◽  
Retention Force ◽  
Powered Toothbrush

The powered toothbrush has become a modern dental tool that is available in the supermarket. Indeed, the design of the powered toothbrush, e.g., mechanical and electrical, would affect not only the efficacy but also the safety of the products. This narrative review attempted to view the powered toothbrush from design, safety, and application points with respect to tufts, filaments, handles, mechanics, motions, and materials interactions from various available sources. Different brands and models of powered toothbrushes have their own designs that might affect the clinical outcome. The rotational design was advocated to be clinically more effective than the manual one, some modern models might be designed with vibrational or oscillation (or mixed) tufts head that might be useful in patients with specific needs, such as having xerostomia or for the elderly. To conclude, tuft retention design is important in the powered toothbrush as it contributes significantly to safety as the fallen off tufts, filaments and metal parts might cause injury. Tests revealing the retention force of brush head plates and brush head bristles will be significant references for consumers to determine which design of powered toothbrushes is relatively safer.

Clinical outcome and long-term survival following radical esophagectomy in the elderly

2001 ◽  
Vol 120 (5) ◽  
pp. A747-A748
Author(s):  
S DRESNER ◽  
A IMMMANUEL ◽  
P LAMB ◽  
S GRIFFIN
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Radical Esophagectomy ◽  
Term Survival ◽  
Long Term Survival

scholarly journals A Narrative Review on Sarcopenia in Type 2 Diabetes Mellitus: Prevalence and Associated Factors

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 183
Author(s):  
Anna Izzo ◽  
Elena Massimino ◽  
Gabriele Riccardi ◽  
Giuseppe Della Pepa
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Population ◽  
The Elderly ◽  
Narrative Review ◽  
Macrovascular Complications ◽  
Diabetic Patients ◽  
Age Related

Type 2 diabetes mellitus (T2DM) represents a major health burden for the elderly population, affecting approximately 25% of people over the age of 65 years. This percentage is expected to increase dramatically in the next decades in relation to the increased longevity of the population observed in recent years. Beyond microvascular and macrovascular complications, sarcopenia has been described as a new diabetes complication in the elderly population. Increasing attention has been paid by researchers and clinicians to this age-related condition—characterized by loss of skeletal muscle mass together with the loss of muscle power and function—in individuals with T2DM; this is due to the heavy impact that sarcopenia may have on physical and psychosocial health of diabetic patients, thus affecting their quality of life. The aim of this narrative review is to provide an update on: (1) the risk of sarcopenia in individuals with T2DM, and (2) its association with relevant features of patients with T2DM such as age, gender, body mass index, disease duration, glycemic control, presence of microvascular or macrovascular complications, nutritional status, and glucose-lowering drugs. From a clinical point of view, it is necessary to improve the ability of physicians and dietitians to recognize early sarcopenia and its risk factors in patients with T2DM in order to make appropriate therapeutic approaches able to prevent and treat this condition.

scholarly journals Single fraction of accelerated partial breast irradiation in the elderly: early clinical outcome

2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Rémy Kinj ◽  
Marie-Eve Chand ◽  
Jocelyn Gal ◽  
Mathieu Gautier ◽  
Lucile Montagné ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
Breast Irradiation ◽  
Single Fraction

scholarly journals Five-year oncological outcome after a single fraction of accelerated partial breast irradiation in the elderly

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Rémy Kinj ◽  
Marie-Eve Chand ◽  
Jocelyn Gal ◽  
Mathieu Gautier ◽  
Daniel Lam Cham Kee ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Late Toxicity ◽  
The Elderly ◽  
Local Relapse ◽  
Accelerated Partial Breast Irradiation ◽  
Partial Breast Irradiation ◽  
High Dose ◽  
Axillary Lymph ◽  
Breast Irradiation ◽  
Single Fraction

Abstract Background To update the clinical outcome of an elderly women cohort with early breast cancer who underwent accelerated partial breast irradiation (APBI) based on a post-operative single fraction of multicatheter interstitial high dose–rate brachytherapy (MIB). Material and methods A single institution retrospective cohort study was performed focusing on elderly patients (≥ 65 years old) presenting a low-risk breast carcinoma treated by lumpectomy plus axillary evaluation followed by MIB APBI. A single fraction of 16 Gy was prescribed on the 100% isodose. Clinical outcome at 5 years was reported based on local relapse free survival (LRFS), specific survival (SS) and overall survival (OS). Late toxicity was evaluated. Cosmetic results were evaluated clinically by the physician. Results Between January 2012 and August 2015, 48 women (51 lesions) were treated. Median age was 77.7 years (range: 65–92) with a median tumor size of 12 mm (range: 3–32). Five patients (pts) presented an axillary lymph node involvement (4 Nmic, 1 N1). Invasive ductal carcinoma was the most frequent histology type (86.3%). With a median follow–up of 64 months (range: 56–71), no local relapse occurred while 1 pt. developed an axillary relapse (2.1%). No Grade 3 or higher late toxicity was observed while 16 late toxicities occurred (G1: 14 events [87.5%) mainly G1 breast fibrosis). The rate of excellent cosmetic outcome was 76.4%. Conclusion We confirmed the safety of the process and remained encouraging clinical outcome of a post-operative single fraction of MIB ABPI in the elderly. This approach leads to consider a very APBI as an attractive alternative to intra-operative radiation therapy while all the patients will be good candidates for APBI in regards to the post-operative pathological report.

scholarly journals Deleterious effects of prolonged bed rest on the body systems of the elderly - a review

2018 ◽  
Vol 21 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Luana Petruccio Cabral Monteiro Guedes ◽  
Maria Liz Cunha de Oliveira ◽  
Gustavo de Azevedo Carvalho
Keyword(s):  
Research Question ◽  
Primary Source ◽  
Bed Rest ◽  
The Elderly ◽  
The Body ◽  
Narrative Review ◽  
Boolean Operator

Abstract Objective: to describe the deleterious effects of prolonged bed rest on the body systems of the elderly. Method: an integrative-narrative review was carried out, with the following research question: What are the effects of prolonged bed rest on the body systems of the elderly? The PubMed and Virtual Health Library databases were searched with the following terms: "bed rest” and "elderly" with the Boolean operator “and”. Results: a total of 1,639 articles were found. After application of the established criteria, nine articles remained, and 20 were added to maintain the citation of the primary source, giving a total of 29 articles. Conclusion: the immobility associated with prolonged bed rest is detrimental to the health of the elderly, as it affects several systems, such as the cardiovascular, pulmonary, gastrointestinal, musculoskeletal and urinary systems, which may lead to the onset of diseases in addition to those that led to bed rest.

Metastatic melanoma in the elderly: Case series of clinical outcome and immune characteristics

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20018-e20018
Author(s):  
U. P. Hegde ◽  
N. Chakraborty ◽  
A. Chhabra ◽  
S. Ray
Keyword(s):  
Immune System ◽  
Clinical Outcome ◽  
Elderly Patients ◽  
Metastatic Melanoma ◽  
Cutaneous Melanoma ◽  
Proliferative Activity ◽  
The Elderly ◽  
High Dose ◽  
The Impact

e20018 Background: Cutaneous melanoma incidence is rapidly rising in the elderly population. Imbalances of the immune system are described due to aging associated changes between CD4+, CD8+, T helper (Th) 1, Th 2 and T regulatory and T effector lymphocytes (lym). We describe clinical outcome in 10 elderly patients (pts) with cutaneous metastatic melanoma (CMM) and results of the immune studies done in a subgroup. Methods: Between October 2002 and October 2008, 10 elderly pts with treatment naïve CMM, 6 males and 4 female, median ages 76, range 57–84 years were treated at the University of Connecticut Health Center. Metastatic sites included soft tissue in 2 patients (pts), lung and/or liver with lymph node (LN) involvement (6 pts) and distant LN metastasis (2pts). Eight pts opted for treatment and received single or combination chemotherapy (5pts), high dose Interleukin 2 (2 pts), complete tumor resection followed by tumor derived heat shock protein vaccine (1 pt on clinical trial) and bio chemotherapy (1pt). One patient declined treatment (included in follow up). In vitro immune characteristics were studied in HLA-A2 positive subgroup (5pts) and included cytotoxic T lym (CTL) generation against self and non self peptides (Mart-1 27–35 and influenza MP derived peptide flu 58–66), proliferative activity of CD4+ lym in response to anti CD3 antibody under Th1 and Th2 conditions and regulatory T lym activity of CD4+CD25+ lym against CTL. Results: All patients tolerated treatments well resulting in 1 complete response, 4 partial responses, and 4 stable diseases. During 6 year follow up period, 6 patients died while 4 patients are living (one with disease). The median survival of all patients is 28.1 month (mo) while in those surviving (4pts) is 72 mo. Immune studies revealed preserved proliferative activity of CD4+ lym with stronger Th1 induction than Th2. The CTL responses to self and non self antigens were preserved while regulatory T lym showed weak activity against CTL. Conclusions: Some elderly patients with metastatic melanoma demonstrate improved outcomes and favorable immune characteristics. Further studies are needed to understand the impact of aging immune system on cutaneous melanoma. No significant financial relationships to disclose.

The Clinical Outcome of Asthma in the Elderly: a 7-Year Follow-Up Study

1991 ◽  
Vol 629 (1 Advances in t) ◽  
pp. 449-450 ◽  
Author(s):  
SIDNEY S. BRAMAN ◽  
WILLIAM M. CORRAO ◽  
JOHN T. KAEMMERLEN
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Follow Up Study
Sign in / Sign up

Export Citation Format

Share Document