scholarly journals Evaluation of Deep Convolutional Generative Adversarial Networks for Data Augmentation of Chest X-ray Images

2020 ◽  
Vol 13 (1) ◽  
pp. 8
Author(s):  
Sagar Kora Venu ◽  
Sridhar Ravula

Medical image datasets are usually imbalanced due to the high costs of obtaining the data and time-consuming annotations. Training a deep neural network model on such datasets to accurately classify the medical condition does not yield the desired results as they often over-fit the majority class samples’ data. Data augmentation is often performed on the training data to address the issue by position augmentation techniques such as scaling, cropping, flipping, padding, rotation, translation, affine transformation, and color augmentation techniques such as brightness, contrast, saturation, and hue to increase the dataset sizes. Radiologists generally use chest X-rays for the diagnosis of pneumonia. Due to patient privacy concerns, access to such data is often protected. In this study, we performed data augmentation on the Chest X-ray dataset to generate artificial chest X-ray images of the under-represented class through generative modeling techniques such as the Deep Convolutional Generative Adversarial Network (DCGAN). With just 1341 chest X-ray images labeled as Normal, artificial samples were created by retaining similar characteristics to the original data with this technique. Evaluating the model resulted in a Fréchet Distance of Inception (FID) score of 1.289. We further show the superior performance of a CNN classifier trained on the DCGAN augmented dataset.

2021 ◽  
Author(s):  
Saman Motamed ◽  
Patrik Rogalla ◽  
Farzad Khalvati

Abstract Successful training of convolutional neural networks (CNNs) requires a substantial amount of data. With small datasets networks generalize poorly. Data Augmentation techniques improve the generalizability of neural networks by using existing training data more effectively. Standard data augmentation methods, however, produce limited plausible alternative data. Generative Adversarial Networks (GANs) have been utilized to generate new data and improve the performance of CNNs. Nevertheless, data augmentation techniques for training GANs are under-explored compared to CNNs. In this work, we propose a new GAN architecture for augmentation of chest X-rays for semi-supervised detection of pneumonia and COVID-19 using generative models. We show that the proposed GAN can be used to effectively augment data and improve classification accuracy of disease in chest X-rays for pneumonia and COVID-19. We compare our augmentation GAN model with Deep Convolutional GAN and traditional augmentation methods (rotate, zoom, etc) on two different X-ray datasets and show our GAN-based augmentation method surpasses other augmentation methods for training a GAN in detecting anomalies in X-ray images.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Saman Motamed ◽  
Patrik Rogalla ◽  
Farzad Khalvati

AbstractCOVID-19 spread across the globe at an immense rate and has left healthcare systems incapacitated to diagnose and test patients at the needed rate. Studies have shown promising results for detection of COVID-19 from viral bacterial pneumonia in chest X-rays. Automation of COVID-19 testing using medical images can speed up the testing process of patients where health care systems lack sufficient numbers of the reverse-transcription polymerase chain reaction tests. Supervised deep learning models such as convolutional neural networks need enough labeled data for all classes to correctly learn the task of detection. Gathering labeled data is a cumbersome task and requires time and resources which could further strain health care systems and radiologists at the early stages of a pandemic such as COVID-19. In this study, we propose a randomized generative adversarial network (RANDGAN) that detects images of an unknown class (COVID-19) from known and labelled classes (Normal and Viral Pneumonia) without the need for labels and training data from the unknown class of images (COVID-19). We used the largest publicly available COVID-19 chest X-ray dataset, COVIDx, which is comprised of Normal, Pneumonia, and COVID-19 images from multiple public databases. In this work, we use transfer learning to segment the lungs in the COVIDx dataset. Next, we show why segmentation of the region of interest (lungs) is vital to correctly learn the task of classification, specifically in datasets that contain images from different resources as it is the case for the COVIDx dataset. Finally, we show improved results in detection of COVID-19 cases using our generative model (RANDGAN) compared to conventional generative adversarial networks for anomaly detection in medical images, improving the area under the ROC curve from 0.71 to 0.77.


2021 ◽  
Author(s):  
Debmitra Ghosh

Abstract SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2 is considered to be the cause of Coronavirus (COVID-19) which is a viral disease. The rapid spread of COVID-19 is having a detrimental effect on the global economy and health. A chest X-ray of infected patients can be considered as a crucial step in the battle against COVID-19. On retrospections, it is found that abnormalities exist in chest X-rays of patients suggestive of COVID-19. This sparked the introduction of a variety of deep learning systems and studies which have shown that the accuracy of COVID-19 patient detection through the use of chest X-rays is strongly optimistic. Although there are certain shortcomings like deep learning networks like convolutional neural networks (CNNs) need a substantial amount of training data but the outbreak is recent, so it is large datasets of radiographic images of the COVID-19 infected patients are not available in such a short time. Here, in this research, we present a method to generate synthetic chest X-ray (CXR) images by developing a Deep Convolution Generative Adversarial Network-based model. In addition, we demonstrate that the synthetic images produced from DCGAN can be utilized to enhance the performance of CNN for COVID-19 detection. Classification using CNN alone yielded 85% accuracy. Although there are several models available, we chose MobileNet as it is a lightweight deep neural network, with fewer parameters and higher classification accuracy. Here we are using a deep neural network-based model to diagnose COVID-19 infected patients through radiological imaging of 5,859 Chest X-Ray images. We are using a Deep Convolutional Neural Network and a pre-trained model “DenseNet 121” for two new label classes (COVID-19 and Normal). To improve the classification accuracy, in our work we have further reduced the number of network parameters by introducing dense blocks that are proposed in DenseNets into MobileNet. By adding synthetic images produced by DCGAN, the accuracy increased to 97%. Our goal is to use this method to speed up COVID-19 detection and lead to more robust systems of radiology.


2021 ◽  
Vol 38 (3) ◽  
pp. 619-627
Author(s):  
Kazim Firildak ◽  
Muhammed Fatih Talu

Pneumonia, featured by inflammation of the air sacs in one or both lungs, is usually detected by examining chest X-ray images. This paper probes into the classification models that can distinguish between normal and pneumonia images. As is known, trained networks like AlexNet and GoogleNet are deep network architectures, which are widely adopted to solve many classification problems. They have been adapted to the target datasets, and employed to classify new data generated through transfer learning. However, the classical architectures are not accurate enough for the diagnosis of pneumonia. Therefore, this paper designs a capsule network with high discrimination capability, and trains the network on Kaggle’s online pneumonia dataset, which contains chest X-ray images of many adults and children. The original dataset consists of 1,583 normal images, and 4,273 pneumonia images. Then, two data augmentation approaches were applied to the dataset, and their effects on classification accuracy were compared in details. The model parameters were optimized through five different experiments. The results show that the highest classification accuracy (93.91% even on small images) was achieved by the capsule network, coupled with data augmentation by generative adversarial network (GAN), using optimized parameters. This network outperformed the classical strategies.


Author(s):  
Sivaramakrishnan Rajaraman ◽  
Sameer Antani

AbstractThe novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused a pandemic resulting in over 2.7 million infected individuals and over 190,000 deaths and growing. Respiratory disorders in COVID-19 caused by the virus commonly present as viral pneumonia-like opacities in chest X-ray images which are used as an adjunct to the reverse transcription-polymerase chain reaction test for confirmation and evaluating disease progression. The surge places high demand on medical services including radiology expertise. However, there is a dearth of sufficient training data for developing image-based automated decision support tools to alleviate radiological burden. We address this insufficiency by expanding training data distribution through use of weakly-labeled images pooled from publicly available CXR collections showing pneumonia-related opacities. We use the images in a stage-wise, strategic approach and train convolutional neural network-based algorithms to detect COVID-19 infections in CXRs. It is observed that weakly-labeled data augmentation improves performance with the baseline test data compared to non-augmented training by expanding the learned feature space to encompass variability in the unseen test distribution to enhance inter-class discrimination, reduce intra-class similarity and generalization error. Augmentation with COVID-19 CXRs from individual collections significantly improves performance compared to baseline non-augmented training and weakly-labeled augmentation toward detecting COVID-19 like viral pneumonia in the publicly available COVID-19 CXR collections. This underscores the fact that COVID-19 CXRs have a distinct pattern and hence distribution, unlike non-COVID-19 viral pneumonia and other infectious agents.


Author(s):  
Lakshmisetty Ruthvik Raj ◽  
◽  
Bitra Harsha Vardhan ◽  
Mullapudi Raghu Vamsi ◽  
Keerthikeshwar Reddy Mamilla ◽  
...  

COVID-19 is a severe and potentially fatal respiratory infection called coronavirus 2 disease (SARS-Co-2). COVID-19 is easily detectable on an abnormal chest x-ray. Numerous extensive studies have been conducted due to the findings, demonstrating how precise the detection of coronas using X-rays within the chest is. To train a deep learning network, such as a convolutional neural network, a large amount of data is required. Due to the recent end of the pandemic, it is difficult to collect many Covid x-ray images in a short period. The purpose of this study is to demonstrate how X-ray imaging (CXR) is created using the Covid CNN model-based convolutional network. Additionally, we demonstrate that the performance of CNNs and various COVID-19 acquisition algorithms can be used to generate synthetic images from data extensions. Alone, with CNN distribution, an accuracy of 85 percent was achieved. The accuracy has been increased to 95% by adding artificial images generated from data. We anticipate that this approach will expedite the discovery of COVID-19 and result in radiological solid programs. We leverage transfer learning in this paper to reduce time complexity and achieve the highest accuracy.


Author(s):  
V. N. Manjunath Aradhya ◽  
Mufti Mahmud ◽  
D. S. Guru ◽  
Basant Agarwal ◽  
M. Shamim Kaiser

AbstractCoronavirus disease (COVID-19) has infected over more than 28.3 million people around the globe and killed 913K people worldwide as on 11 September 2020. With this pandemic, to combat the spreading of COVID-19, effective testing methodologies and immediate medical treatments are much required. Chest X-rays are the widely available modalities for immediate diagnosis of COVID-19. Hence, automation of detection of COVID-19 from chest X-ray images using machine learning approaches is of greater demand. A model for detecting COVID-19 from chest X-ray images is proposed in this paper. A novel concept of cluster-based one-shot learning is introduced in this work. The introduced concept has an advantage of learning from a few samples against learning from many samples in case of deep leaning architectures. The proposed model is a multi-class classification model as it classifies images of four classes, viz., pneumonia bacterial, pneumonia virus, normal, and COVID-19. The proposed model is based on ensemble of Generalized Regression Neural Network (GRNN) and Probabilistic Neural Network (PNN) classifiers at decision level. The effectiveness of the proposed model has been demonstrated through extensive experimentation on a publicly available dataset consisting of 306 images. The proposed cluster-based one-shot learning has been found to be more effective on GRNN and PNN ensembled model to distinguish COVID-19 images from that of the other three classes. It has also been experimentally observed that the model has a superior performance over contemporary deep learning architectures. The concept of one-shot cluster-based learning is being first of its kind in literature, expected to open up several new dimensions in the field of machine learning which require further researching for various applications.


Mathematics ◽  
2021 ◽  
Vol 9 (22) ◽  
pp. 2896
Author(s):  
Giorgio Ciano ◽  
Paolo Andreini ◽  
Tommaso Mazzierli ◽  
Monica Bianchini ◽  
Franco Scarselli

Multi-organ segmentation of X-ray images is of fundamental importance for computer aided diagnosis systems. However, the most advanced semantic segmentation methods rely on deep learning and require a huge amount of labeled images, which are rarely available due to both the high cost of human resources and the time required for labeling. In this paper, we present a novel multi-stage generation algorithm based on Generative Adversarial Networks (GANs) that can produce synthetic images along with their semantic labels and can be used for data augmentation. The main feature of the method is that, unlike other approaches, generation occurs in several stages, which simplifies the procedure and allows it to be used on very small datasets. The method was evaluated on the segmentation of chest radiographic images, showing promising results. The multi-stage approach achieves state-of-the-art and, when very few images are used to train the GANs, outperforms the corresponding single-stage approach.


2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Khaled Almezhghwi ◽  
Sertan Serte

White blood cells (leukocytes) are a very important component of the blood that forms the immune system, which is responsible for fighting foreign elements. The five types of white blood cells include neutrophils, eosinophils, lymphocytes, monocytes, and basophils, where each type constitutes a different proportion and performs specific functions. Being able to classify and, therefore, count these different constituents is critical for assessing the health of patients and infection risks. Generally, laboratory experiments are used for determining the type of a white blood cell. The staining process and manual evaluation of acquired images under the microscope are tedious and subject to human errors. Moreover, a major challenge is the unavailability of training data that cover the morphological variations of white blood cells so that trained classifiers can generalize well. As such, this paper investigates image transformation operations and generative adversarial networks (GAN) for data augmentation and state-of-the-art deep neural networks (i.e., VGG-16, ResNet, and DenseNet) for the classification of white blood cells into the five types. Furthermore, we explore initializing the DNNs’ weights randomly or using weights pretrained on the CIFAR-100 dataset. In contrast to other works that require advanced image preprocessing and manual feature extraction before classification, our method works directly with the acquired images. The results of extensive experiments show that the proposed method can successfully classify white blood cells. The best DNN model, DenseNet-169, yields a validation accuracy of 98.8%. Particularly, we find that the proposed approach outperforms other methods that rely on sophisticated image processing and manual feature engineering.


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