scholarly journals Hydrogel Nanofibers from Carboxymethyl Sago Pulp and Its Controlled Release Studies as a Methylene Blue Drug Carrier

Fibers ◽  
2019 ◽  
Vol 7 (6) ◽  
pp. 56 ◽  
Author(s):  
Nafeesa Mohd Kanafi ◽  
Norizah Abdul Rahman ◽  
Nurul Husna Rosdi ◽  
Hasliza Bahruji ◽  
Hasmerya Maarof
Keyword(s):  
Methylene Blue ◽  
Citric Acid ◽  
Controlled Release ◽  
Drug Carrier ◽  
Curing Temperature ◽  
Buffer Solution ◽  
Release Studies ◽  
Electrospinning Method ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

The potential use of carboxymethyl sago pulp (CMSP) extracted from sago waste for producing hydrogel nanofibers was investigated as a methylene blue drug carrier. Sago pulp was chemically modified via carboxymethylation reaction to form carboxymethyl sago pulp (CMSP) and subsequently used to produce nanofibers using the electrospinning method with the addition of poly(ethylene oxide) (PEO). The CMSP nanofibers were further treated with citric acid to form cross-linked hydrogel. Studies on the percentage of swelling following the variation of citric acid concentrations and curing temperature showed that 89.20 ± 0.42% of methylene blue (MB) was loaded onto CMSP hydrogel nanofibers with the percentage of swelling 4366 ± 975%. Meanwhile, methylene blue controlled release studies revealed that the diffusion of methylene blue was influenced by the pH of buffer solution with 19.44% of MB released at pH 7.34 within 48 h indicating the potential of CMSP hydrogel nanofibers to be used as a drug carrier for MB.

scholarly journals Degradable Poly(ethylene oxide)-Like Plasma Polymer Films Used for the Controlled Release of Nisin

Polymers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1263 ◽  
Author(s):  
Jaroslav Kousal ◽  
Jana Sedlaříková ◽  
Zuzana Kolářová-Rašková ◽  
Zdeněk Krtouš ◽  
Liliana Kučerová ◽  
...  
Keyword(s):  
Controlled Release ◽  
Ethylene Oxide ◽  
Biologically Active ◽  
Process Conditions ◽  
Plasma Power ◽  
Permeability Study ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Atr Spectroscopy ◽  
Permeation Properties

Poly(ethylene oxide) (PEO)-like thin films were successfully prepared by plasma-assisted vapor thermal deposition (PAVTD). PEO powders with a molar weight (Mw) between 1500 g/mol and 600,000 g/mol were used as bulk precursors. The effect of Mw on the structural and surface properties was analyzed for PEO films prepared at a lower plasma power. Fourier transform (FTIR-ATR) spectroscopy showed that the molecular structure was well preserved regardless of the Mw of the precursors. The stronger impact of the process conditions (the presence/absence of plasma) was proved. Molecular weight polydispersity, as well as wettability, increased in the samples prepared at 5 W. The influence of deposition plasma power (0–30 W) on solubility and permeation properties was evaluated for a bulk precursor of Mw 1500 g/mol. The rate of thickness loss after immersion in water was found to be tunable in this way, with the films prepared at the highest plasma power showing higher stability. The effect of plasma power deposition conditions was also shown during the permeability study. Prepared PEO films were used as a cover, and permeation layers for biologically active nisin molecule and a controlled release of this bacteriocin into water was achieved.

scholarly journals Fabrication of SnO2 Composite Nanofiber-Based Gas Sensor Using the Electrospinning Method for Tetrahydrocannabinol (THC) Detection

Micromachines ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 190 ◽  
Author(s):  
Pouria Mehrabi ◽  
Justin Hui ◽  
Sajjad Janfaza ◽  
Allen O’Brien ◽  
Nishat Tasnim ◽  
...  
Keyword(s):  
Tin Dioxide ◽  
High Sensitivity ◽  
Oxide Semiconductor ◽  
Calcination Temperatures ◽  
Electrospinning Method ◽  
Gold Doping ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene ◽  
Mos Sensor ◽  
Fabrication Parameters

This paper presents the development of a metal oxide semiconductor (MOS) sensor for the detection of volatile organic compounds (VOCs) which are of great importance in many applications involving either control of hazardous chemicals or noninvasive diagnosis. In this study, the sensor is fabricated based on tin dioxide (SnO2) and poly(ethylene oxide) (PEO) using electrospinning. The sensitivity of the proposed sensor is further improved by calcination and gold doping. The gold doping of composite nanofibers is achieved using sputtering, and the calcination is performed using a high-temperature oven. The performance of the sensor with different doping thicknesses and different calcination temperatures is investigated to identify the optimum fabrication parameters resulting in high sensitivity. The optimum calcination temperature and duration are found to be 350 °C and 4 h, respectively and the optimum thickness of the gold dopant is found to be 10 nm. The sensor with the optimum fabrication process is then embedded in a microchannel coated with several metallic and polymeric layers. The performance of the sensor is compared with that of a commercial sensor. The comparison is performed for methanol and a mixture of methanol and tetrahydrocannabinol (THC) which is the primary psychoactive constituent of cannabis. It is shown that the proposed sensor outperforms the commercial sensor when it is embedded inside the channel.

Sign in / Sign up

Export Citation Format

Share Document